Silence Therapeutics (SLN) Aktievy
Silence Therapeutics plc, ett bioteknikföretag, bedriver forskning och utveckling av nya molekyler som innehåller kort interfererande ribonukleinsyra (siRNA) för att hämma uttrycket av specifika målgener inom hematologi, kardiovaskulära och sällsynta sjukdomar. Mer information
| Snöflinga Score | |
|---|---|
| Värdering | 0/6 |
| Framtida tillväxt | 2/6 |
| Tidigare resultat | 0/6 |
| Finansiell hälsa | 6/6 |
| Utdelningar | 0/6 |
Belöningar
Riskanalys
SLN Community Fair Values
Create NarrativeSee what 17 others think this stock is worth. Follow their fair value or set your own to get alerts.
Analyst Price Targets
Silence Therapeutics plc Konkurrenter
Prishistorik och prestanda
| Historiska aktiekurser | |
|---|---|
| Aktuell aktiekurs | US$11.55 |
| 52 veckors högsta | US$12.19 |
| 52 veckors lägsta | US$4.19 |
| Beta | 1.38 |
| 1 månads förändring | 13.91% |
| 3 månaders förändring | 62.45% |
| 1 års förändring | 86.29% |
| 3 års förändring | 122.12% |
| 5 års förändring | -54.88% |
| Förändring sedan börsintroduktionen | -40.77% |
Senaste nyheter och uppdateringar
Seeking Alpha • Jul 12
Silence Therapeutics: PV Data Could Wake The Stock (Initiating Buy)
Summary I initiate Silence Therapeutics at a speculative Buy, driven by near-term divesiran/SLN124 catalysts in polycythemia vera (PV). SLN’s mRNAi GOLD GalNAc-siRNA platform enables infrequent dosing and strong target knockdown, potentially differentiating divesiran from weekly competitors like Rusfertide. Phase 1 SANRECO data show promising phlebotomy reduction and symptom improvement, but safety and efficacy require confirmation in the pivotal Phase 2 readout (August 2026). SLN faces high clinical, financial, and competitive risks, but discounted valuation and Lp(a) optionality create a compelling risk-reward ahead of the binary Phase 2 catalyst. Read the full article on Seeking Alpha
Uppdatering av berättelse • Jun 15
SLN: Upcoming Phase 2 Data And ATM Program Will Shape Upside Potential
Analysts have kept their $31.20 price target for Silence Therapeutics unchanged, with only minor tweaks to inputs such as discount rate, profit margin and forward P/E assumptions informing the latest update. What's in the News Silence Therapeutics presented follow-up and quality-of-life data from the Phase 1 SANRECO study of divesiran in 21 phlebotomy-dependent polycythemia vera patients at the European Hematology Association 2026 Annual Congress, showing fewer required phlebotomies during and after treatment and reported improvements in PV-related symptoms and overall quality of life.Recent updates
Seeking Alpha • Jul 12
Silence Therapeutics: PV Data Could Wake The Stock (Initiating Buy)
Summary I initiate Silence Therapeutics at a speculative Buy, driven by near-term divesiran/SLN124 catalysts in polycythemia vera (PV). SLN’s mRNAi GOLD GalNAc-siRNA platform enables infrequent dosing and strong target knockdown, potentially differentiating divesiran from weekly competitors like Rusfertide. Phase 1 SANRECO data show promising phlebotomy reduction and symptom improvement, but safety and efficacy require confirmation in the pivotal Phase 2 readout (August 2026). SLN faces high clinical, financial, and competitive risks, but discounted valuation and Lp(a) optionality create a compelling risk-reward ahead of the binary Phase 2 catalyst. Read the full article on Seeking AlphaUppdatering av berättelse • Jun 15
SLN: Upcoming Phase 2 Data And ATM Program Will Shape Upside Potential
Analysts have kept their $31.20 price target for Silence Therapeutics unchanged, with only minor tweaks to inputs such as discount rate, profit margin and forward P/E assumptions informing the latest update. What's in the News Silence Therapeutics presented follow-up and quality-of-life data from the Phase 1 SANRECO study of divesiran in 21 phlebotomy-dependent polycythemia vera patients at the European Hematology Association 2026 Annual Congress, showing fewer required phlebotomies during and after treatment and reported improvements in PV-related symptoms and overall quality of life.Uppdatering av berättelse • Jun 01
SLN: Future Offering Program Will Shape Upside Risk Reward Profile
Analysts have adjusted their price target on Silence Therapeutics to $31.20. This reflects updated assumptions around growth, profitability and a higher future P/E multiple that together indicate a different risk and reward profile than before.Analysartikel • Feb 05
Revenues Working Against Silence Therapeutics plc's (NASDAQ:SLN) Share Price Following 27% Dive
To the annoyance of some shareholders, Silence Therapeutics plc ( NASDAQ:SLN ) shares are down a considerable 27% in...Analysartikel • Jan 31
Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation
There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...Analysartikel • Oct 19
Here's Why We're Watching Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation
There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...Analysartikel • Sep 28
Pinning Down Silence Therapeutics plc's (NASDAQ:SLN) P/S Is Difficult Right Now
With a median price-to-sales (or "P/S") ratio of close to 9.9x in the Biotechs industry in the United States, you could...Analysartikel • Aug 13
Newsflash: Silence Therapeutics plc (NASDAQ:SLN) Analysts Have Been Trimming Their Revenue Forecasts
NasdaqGM:SLN 1 Year Share Price vs Fair Value Explore Silence Therapeutics's Fair Values from the Community and select...Analysartikel • Aug 12
Silence Therapeutics plc (NASDAQ:SLN) Second-Quarter Results: Here's What Analysts Are Forecasting For This Year
NasdaqGM:SLN 1 Year Share Price vs Fair Value Explore Silence Therapeutics's Fair Values from the Community and select...Uppdatering av berättelse • Aug 08
ALPACAR-360 Success And AstraZeneca Collaboration Will Advance siRNA Pipeline
The upward revision in Silence Therapeutics’ price target reflects significantly improved consensus revenue growth forecasts and a lower future P/E multiple, resulting in an increased fair value estimate from $32.37 to $37.26. What's in the News Silence Therapeutics approved the application of Article 159 of its articles of association, effective from the recent AGM to the next annual general meeting.Analysartikel • May 11
Silence Therapeutics plc (NASDAQ:SLN) First-Quarter Results Just Came Out: Here's What Analysts Are Forecasting For This Year
The analysts might have been a bit too bullish on Silence Therapeutics plc ( NASDAQ:SLN ), given that the company fell...Analysartikel • May 06
Silence Therapeutics plc's (NASDAQ:SLN) Price Is Right But Growth Is Lacking After Shares Rocket 50%
Those holding Silence Therapeutics plc ( NASDAQ:SLN ) shares would be relieved that the share price has rebounded 50...
Ny berättelse • Apr 01
ALPACAR-360 Success And AstraZeneca Collaboration Will Advance siRNA Pipeline
The company's strategic partnerships and collaborations could reduce financial risk and enhance revenue growth through shared commercialization and milestone payments.Analysartikel • Mar 22
Silence Therapeutics plc (NASDAQ:SLN) Looks Inexpensive After Falling 29% But Perhaps Not Attractive Enough
Unfortunately for some shareholders, the Silence Therapeutics plc ( NASDAQ:SLN ) share price has dived 29% in the last...Analysartikel • Mar 06
These Analysts Think Silence Therapeutics plc's (NASDAQ:SLN) Sales Are Under Threat
Market forces rained on the parade of Silence Therapeutics plc ( NASDAQ:SLN ) shareholders today, when the analysts...Analysartikel • Mar 04
We're Keeping An Eye On Silence Therapeutics' (NASDAQ:SLN) Cash Burn Rate
Just because a business does not make any money, does not mean that the stock will go down. For example, although...Analysartikel • Jan 28
Risks Still Elevated At These Prices As Silence Therapeutics plc (NASDAQ:SLN) Shares Dive 26%
Unfortunately for some shareholders, the Silence Therapeutics plc ( NASDAQ:SLN ) share price has dived 26% in the last...Analysartikel • Dec 10
Silence Therapeutics plc (NASDAQ:SLN) May Have Run Too Fast Too Soon With Recent 54% Price Plummet
Silence Therapeutics plc ( NASDAQ:SLN ) shareholders that were waiting for something to happen have been dealt a blow...Analysartikel • Oct 04
Some Shareholders Feeling Restless Over Silence Therapeutics plc's (NASDAQ:SLN) P/S Ratio
You may think that with a price-to-sales (or "P/S") ratio of 38.4x Silence Therapeutics plc ( NASDAQ:SLN ) is a stock...Analysartikel • Aug 18
Silence Therapeutics plc (NASDAQ:SLN) Consensus Forecasts Have Become A Little Darker Since Its Latest Report
As you might know, Silence Therapeutics plc ( NASDAQ:SLN ) last week released its latest second-quarter, and things did...Analysartikel • Jun 17
Silence Therapeutics plc's (NASDAQ:SLN) Shareholders Might Be Looking For Exit
You may think that with a price-to-sales (or "P/S") ratio of 26.8x Silence Therapeutics plc ( NASDAQ:SLN ) is a stock...Analysartikel • May 21
Here's Why We're Not Too Worried About Silence Therapeutics' (NASDAQ:SLN) Cash Burn Situation
We can readily understand why investors are attracted to unprofitable companies. By way of example, Silence...Analysartikel • Feb 07
Need To Know: Analysts Are Much More Bullish On Silence Therapeutics plc (NASDAQ:SLN) Revenues
Silence Therapeutics plc ( NASDAQ:SLN ) shareholders will have a reason to smile today, with the analysts making...Analysartikel • Nov 27
Subdued Growth No Barrier To Silence Therapeutics plc (NASDAQ:SLN) With Shares Advancing 65%
Silence Therapeutics plc ( NASDAQ:SLN ) shares have had a really impressive month, gaining 65% after a shaky period...Seeking Alpha • Sep 08
Silence Therapeutics wins FDA’s fast track status for blood cancer therapy
U.K.-based clinical-stage biotech Silence Therapeutics plc (NASDAQ:SLN) announced Thursday that the FDA granted Fast Track Designation to SLN124 as a treatment for polycythemia vera (PV), a type of blood cancer. SLN124, belonging to a drug class called short interfering ribonucleic acid (siRNA) therapeutics, is set to undergo a Phase 1/2 study in PV this year. The FDA offers the Fast Track designation to accelerate the development and review of drugs targeted at serious conditions with unmet medical needs. It allows developers to communicate frequently with the regulator on plans for clinical studies. If certain criteria are met, such programs will also be able to win the Accelerated Approval and Priority Review, enabling them to reach patients sooner. In a clinical trial last year, SLN124 indicated proof of mechanism and was well tolerated among healthy volunteers.Seeking Alpha • Aug 12
Silence Therapeutics prices 5.95M ADSs at $9.50/share
Silence Therapeutics (NASDAQ:SLN) has priced an underwritten offering of 5.95M American Depositary Shares, each representing three ordinary shares, at a price of $9.50/ADS, for aggregate gross proceeds of ~$56.5M. All of the ADSs are being offered by Silence. Offering is expected to close on or about August 16, 2022. Silence intends to use the net proceeds of the offering, together with its existing cash and cash equivalents to fund the advancement of its clinical trials, including its Phase 2 trial of SLN360 in ASCVD and its Phase 1/2 trial of SLN124 in polycythemia vera, as well as expansion of pipeline programs, working capital and general corporate purposes.Aktieägarnas avkastning
| SLN | US Biotechs | US Marknad | |
|---|---|---|---|
| 7D | 6.5% | 0.9% | -1.5% |
| 1Y | 86.3% | 33.8% | 16.0% |
Avkastning vs industri: SLN översteg US Biotechs branschen som gav 33.8 % under det senaste året.
Avkastning vs Marknaden: SLN översteg US marknaden som gav 16 % under det senaste året.
Prisvolatilitet
| SLN volatility | |
|---|---|
| SLN Average Weekly Movement | 13.6% |
| Biotechs Industry Average Movement | 10.1% |
| Market Average Movement | 7.2% |
| 10% most volatile stocks in US Market | 16.1% |
| 10% least volatile stocks in US Market | 3.2% |
Stabil aktiekurs: SLN s aktiekurs har varit volatil under de senaste 3 månaderna jämfört med marknaden för US.
Volatilitet över tid: SLN s veckovolatilitet ( 14% ) har varit stabil under det senaste året, men är fortfarande högre än 75 % av US aktier.
Om företaget
| Grundad | Anställda | VD OCH KONCERNCHEF | Webbplats |
|---|---|---|---|
| 1994 | 88 | Iain Ross | www.silence-therapeutics.com |
Silence Therapeutics plc är ett bioteknikföretag som bedriver forskning och utveckling av nya molekyler som innehåller kort interfererande ribonukleinsyra (siRNA) för att hämma uttrycket av specifika målgener inom hematologi, kardiovaskulära och sällsynta sjukdomar. Företaget utvecklar Divesiran (SLN124), som befinner sig i fas 2-utveckling för polycytemia vera, och SLN548 för komplementmedierade njursjukdomar. Företaget utvecklar också Zerlasiran (SLN360) för hjärt- och kärlsjukdomar i samband med förhöjt lipoprotein(a), SLN312 för dyslipidemi, SLN365 för hyperkolesterolemi och SLN098 för fetma.
Silence Therapeutics plc Sammanfattning av grunderna
| SLN grundläggande statistik | |
|---|---|
| Börsvärde | US$570.11m |
| Vinst(TTM) | -US$75.04m |
| Intäkter(TTM) | US$839.00k |
650.2x
P/S-förhållande-7.3x
P/E-förhållandeÄr SLN övervärderat?
Se Verkligt värde och värderingsanalysResultat & intäkter
| SLN resultaträkning (TTM) | |
|---|---|
| Intäkter | US$839.00k |
| Kostnad för intäkter | US$172.00k |
| Bruttovinst | US$667.00k |
| Övriga kostnader | US$75.71m |
| Intäkter | -US$75.04m |
Senast redovisade vinst
Mar 31, 2026
Nästa vinstdatum
n/a
| Vinst per aktie (EPS) | -1.59 |
| Bruttomarginal | 79.50% |
| Nettovinstmarginal | -8,943.86% |
| Skuld/egenkapitalförhållande | 0% |
Hur har SLN utvecklats på lång sikt?
Se historisk utveckling och jämförelseFöretagsanalys och finansiella data Status
| Uppgifter | Senast uppdaterad (UTC-tid) |
|---|---|
| Analys av företag | 2026/07/28 21:22 |
| Aktiekurs vid dagens slut | 2026/07/28 00:00 |
| Intäkter | 2026/03/31 |
| Årlig intjäning | 2025/12/31 |
Datakällor
Den data som används i vår företagsanalys kommer från S&P Global Market Intelligence LLC. Följande data används i vår analysmodell för att generera denna rapport. Data är normaliserade vilket kan medföra en fördröjning från det att källan är tillgänglig.
| Paket | Uppgifter | Tidsram | Exempel US-källa |
|---|---|---|---|
| Företagets finansiella ställning | 10 år |
| |
| Analytikernas konsensusuppskattningar | +3 år |
|
|
| Marknadspriser | 30 år |
| |
| Ägarskap | 10 år |
| |
| Förvaltning | 10 år |
| |
| Viktiga utvecklingstendenser | 10 år |
|
* Exempel för amerikanska värdepapper, för icke-amerikanska värdepapper används motsvarande regelverk och källor.
Om inget annat anges är all finansiell data baserad på en årsperiod men uppdateras kvartalsvis. Detta kallas data för efterföljande tolv månader (TTM) eller senaste tolv månader (LTM). Lär dig mer om detta.
Analysmodell och snöflinga
Detaljer om analysmodellen som används för att skapa den här rapporten finns på vår Github-sida, vi har också guider om hur du använder våra rapporter och handledningar på Youtube.
Lär dig mer om det team i världsklass som utformade och byggde analysmodellen Simply Wall St.
Industri- och sektormått
Våra bransch- och sektionsmått beräknas var sjätte timme av Simply Wall St, detaljer om vår process finns tillgängliga på Github.
Källor för analytiker
Silence Therapeutics plc bevakas av 14 analytiker. 7 av dessa analytiker lämnade de uppskattningar av intäkter eller resultat som användes som indata till vår rapport. Analytikernas inskickade estimat uppdateras löpande under dagen.
| Analytiker | Institution |
|---|---|
| Howard Miller | Canaccord Genuity |
| Prakhar Agrawal | Cantor Fitzgerald & Co. |
| Keay Nakae | Chardan Capital Markets, LLC |