Palisade Bio (PALI) Aktievy

Palisade Bio, Inc. är ett biofarmaceutiskt företag i klinisk fas som utvecklar orala fosfodiesteras-4-hämmande prodroger avsedda för riktad leverans till terminala ileum och kolon i USA. Mer information

PALI fundamental analys
Snöflinga Score
Värdering	1/6
Framtida tillväxt	0/6
Tidigare resultat	0/6
Finansiell hälsa	6/6
Utdelningar	0/6

Riskanalys

Aktieägarna har varit kraftigt utspädda under det senaste året

Ger mindre än 1 miljon USD i intäkter ( $0 )

För närvarande olönsamt och förväntas inte bli lönsamt under de kommande 3 åren

Volatil aktiekurs under de senaste 3 månaderna jämfört med US -marknaden

PALI Community Fair Values

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Palisade Bio, Inc. Konkurrenter

Prishistorik och prestanda

Sammanfattning av aktiekursernas upp- och nedgångar samt förändringar för Palisade Bio
Historiska aktiekurser
Aktuell aktiekurs	US$1.88
52 veckors högsta	US$2.86
52 veckors lägsta	US$0.53
Beta	1.53
1 månads förändring	-24.80%
3 månaders förändring	15.34%
1 års förändring	147.04%
3 års förändring	-91.36%
5 års förändring	-99.90%
Förändring sedan börsintroduktionen	-99.90%

Senaste nyheter och uppdateringar

Recent updates

Seeking Alpha • Dec 23

Palisade Bio: Gut Prodrug For IBD With Catalysts

Summary Palisade Bio’s bull thesis centers on PALI-2108. This is a gut-targeted PDE4 prodrug aiming for local efficacy with fewer systemic PDE4 side effects. The main target indications are UC and FSCD, which promise a sizable TAM if PALI-2108 ultimately succeeds. Naturally, this means PALI’s story remains early-stage and highly data-dependent. Yet, they have a compelling near-term catalyst stack. PALI’s recent October 2025 raise also materially improved their cash runway and liquidity. Using those numbers, its valuation looks compelling relative to its peers. Thus, I lean towards a speculative "Buy" rating on PALI. Read the full article on Seeking Alpha

Seeking Alpha • Oct 11

Palisade Bio announces CEO transition

Palisade Bio (NASDAQ:PALI) announced an executive leadership transition effective October 10, 2022, Thomas Hallam, Ph.D., ceased his duties as CEO. The company’s board of directors has appointed JD Finley, current CFO, as interim CEO, and Mr. Finley has assumed the duties of Dr. Hallam effective October 10, 2022. Prior to joining Palisade Bio, Mr. Finley was the CEO, president and CFO for PointAcross, a software company providing business messaging and communications services.

Seeking Alpha • Sep 15

Palisade Bio streamlines operations, including cutting 20% of employees

Palisade Bio (NASDAQ:PALI) is undergoing a program to streamline operations that includes focusing on lead clinical program LB1148 and laying off 20% of its staff. The gastrointestinal-focused biotech said it is implementing cost-savings measures of more than $1.5M per year. LB1148, a broad-spectrum serine protease inhibitor, is in phase 3 for GI surgery and phase 2 for cardiovascular surgery, both in terms of accelerating return of postoperative GI function. It is also in phase 2 in GI surgery for prevention of post-surgical abdominal adhesions. Seeking Alpha's Quant Rating views Palisade Bio (PALI) as a hold with high marks for valuation, profitability, and revisions.

Seeking Alpha • Aug 15

Palisade Bio GAAP EPS of -$0.12

Palisade Bio press release (NASDAQ:PALI): Q2 GAAP EPS of -$0.12. As of June 30, 2022, the company had cash and cash equivalents of $5M

Seeking Alpha • Jul 27

Palisade Bio begins phase 3 study testing LB1148 for postoperative return of bowel function

Palisade Bio (NASDAQ:PALI) said on Wednesday the first patient had been screened in a Phase 3 study testing its drug, LB1148, to help return bowel function in adult patients undergoing gastrointestinal surgery. The company said it was working to enroll patients and expects to complete enrollment within the next 18-24 months. The drug LB1148 is being developed for administration before the surgeries. The trial is set to enroll about 600 patients and will assess the safety and efficacy of LB1148. The primary endpoint is time to recovery of the upper and lower gastrointestinal tract following surgery. (PALI) rose 1.3% before the bell.

Seeking Alpha • Jun 29

Palisade Bio rises 10% after starting phase 3 study of gastrointestinal surgery therapy

Palisade Bio (NASDAQ:PALI) is trading 10% higher after it begun Phase 3 study evaluating its drug, LB1148, to help return bowel function in patients undergoing gastrointestinal surgery. The late-stage study will enroll about 600 patients. The primary endpoint of the study is time to recovery of the upper and lower gastrointestinal tract following surgery, which is defined as the time from the end of surgery to the toleration of food and first bowel movement.

Analysartikel • Mar 28

Palisade Bio (NASDAQ:PALI) Will Have To Spend Its Cash Wisely

Just because a business does not make any money, does not mean that the stock will go down. For example, although...

Aktieägarnas avkastning

	PALI	US Biotechs	US Marknad
7D	0.5%	-3.0%	-0.3%
1Y	147.0%	32.9%	26.7%

Avkastning vs industri: PALI översteg US Biotechs branschen som gav 32.9 % under det senaste året.

Avkastning vs Marknaden: PALI översteg US marknaden som gav 26.7 % under det senaste året.

Prisvolatilitet

Is PALI's price volatile compared to industry and market?
PALI volatility
PALI Average Weekly Movement	12.7%
Biotechs Industry Average Movement	10.9%
Market Average Movement	7.2%
10% most volatile stocks in US Market	16.2%
10% least volatile stocks in US Market	3.2%

Stabil aktiekurs: PALI s aktiekurs har varit volatil under de senaste 3 månaderna jämfört med marknaden för US.

Volatilitet över tid: PALI s veckovolatilitet har minskat från 18% till 13% under det senaste året, men är fortfarande högre än 75 % av US aktier.

Om företaget

Grundad	Anställda	VD OCH KONCERNCHEF	Webbplats
2001	14	J. Finley	www.palisadebio.com

Palisade Bio, Inc. är ett biofarmaceutiskt företag i klinisk fas som utvecklar orala fosfodiesteras-4-hämmande prodroger avsedda för riktad tillförsel till terminala ileum och kolon i USA. Bolagets ledande kliniska produktkandidat är PALI-2108, som befinner sig i klinisk fas 1b-studie för behandling av patienter med inflammatorisk tarmsjukdom, inklusive ulcerös kolit och fibrostenotisk Crohns sjukdom. Bolaget har ett forskningssamarbete och licensavtal med Giiant Pharma, Inc. för utveckling, tillverkning och kommersialisering av sina substanser, ett licensavtal med Regents of the University of California för det enda syftet att upprätthålla Newsoara Co-Development samt ett avtal om gemensam utveckling och distribution med Newsoara Biopharma Co., Ltd.

Palisade Bio, Inc. Sammanfattning av grunderna

Hur förhåller sig Palisade Bio:s resultat och omsättning till dess börsvärde?
PALI grundläggande statistik
Börsvärde	US$303.04m
Vinst(TTM)	-US$24.15m
Intäkter(TTM)	n/a

0.0x

P/S-förhållande

-13.0x

P/E-förhållande

Är PALI övervärderat?

Se Verkligt värde och värderingsanalys

Resultat & intäkter

Viktig lönsamhetsstatistik från den senaste resultatrapporten (TTM)
PALI resultaträkning (TTM)
Intäkter	US$0
Kostnad för intäkter	US$0
Bruttovinst	US$0
Övriga kostnader	US$24.15m
Intäkter	-US$24.15m

Senast redovisade vinst

Mar 31, 2026

Nästa vinstdatum

n/a

Vinst per aktie (EPS)	-0.14
Bruttomarginal	0.00%
Nettovinstmarginal	0.00%
Skuld/egenkapitalförhållande	0%

Hur har PALI utvecklats på lång sikt?

Se historisk utveckling och jämförelse

Företagsanalys och finansiella data Status

Uppgifter	Senast uppdaterad (UTC-tid)
Analys av företag	2026/05/20 09:46
Aktiekurs vid dagens slut	2026/05/20 00:00
Intäkter	2026/03/31
Årlig intjäning	2025/12/31

Datakällor

Den data som används i vår företagsanalys kommer från S&P Global Market Intelligence LLC. Följande data används i vår analysmodell för att generera denna rapport. Data är normaliserade vilket kan medföra en fördröjning från det att källan är tillgänglig.

Paket	Uppgifter	Tidsram	Exempel US-källa
Företagets finansiella ställning	10 år	Resultaträkning Kassaflödesanalys Balansräkning	SEC Form 10-K SEC Form 10-Q
Analytikernas konsensusuppskattningar	+3 år	Prognos för finansiella poster Analytikernas prismål	Rapporter från analytiker Blue Matrix
Marknadspriser	30 år	Aktiekurser Utdelningar, splittar och åtgärder	ICE Marknadsdata SEC Form S-1
Ägarskap	10 år	Största aktieägare Insiderhandel	SEC Formulär 4 SEC Formulär 13D
Förvaltning	10 år	Ledningsgrupp Styrelse och verkställande direktörer	SEC Form 10-K SEC Form DEF 14A
Viktiga utvecklingstendenser	10 år	Företagsmeddelanden	SEC Formulär 8-K

^* Exempel för amerikanska värdepapper, för icke-amerikanska värdepapper används motsvarande regelverk och källor.

Om inget annat anges är all finansiell data baserad på en årsperiod men uppdateras kvartalsvis. Detta kallas data för efterföljande tolv månader (TTM) eller senaste tolv månader (LTM). Lär dig mer om detta.

Analysmodell och snöflinga

Detaljer om analysmodellen som användes för att skapa den här rapporten finns på vår Github-sida, vi har också guider om hur du använder våra rapporter och tutorials på Youtube.

Lär dig mer om det team i världsklass som utformade och byggde analysmodellen Simply Wall St.

Industri- och sektormått

Våra bransch- och sektionsmått beräknas var sjätte timme av Simply Wall St, detaljer om vår process finns tillgängliga på Github.

Källor för analytiker

Palisade Bio, Inc. bevakas av 9 analytiker. 6 av dessa analytiker lämnade de uppskattningar av intäkter eller resultat som användes som indata till vår rapport. Analytikernas inskickade estimat uppdateras löpande under dagen.

Analytiker	Institution
William Wood	B. Riley Securities, Inc.
Kumaraguru Raja	Brookline Capital Markets
Mitchell Kapoor	H.C. Wainwright & Co.

Palisade Bio (PALI) Aktievy

Riskanalys

Palisade Bio, Inc. Konkurrenter

Benitec Biopharma

SAB Biotherapeutics

Inhibikase Therapeutics

Unicycive Therapeutics

Prishistorik och prestanda

Senaste nyheter och uppdateringar

Palisade Bio Inc Reports Additional Phase 1a/b Data Demonstrating Colon-Targeted Exposure And Sustained IC90 Coverage Supporting Once-Daily Dosing In Ulcerative Colitis

Palisade Bio, Inc., Annual General Meeting, Jun 10, 2026

Price target increased by 7.7% to US$11.13

Palisade Bio, Inc. Reports Positive Topline Data From Phase 1b Clinical Study of PALI-2108 in Fibrostenotic Crohn’s Disease

Palisade Bio, Inc. Reports Rapid Clinical, Histologic and New Mechanistic Colon Tissue RNA Sequencing Data Supporting Targeted Activity of PALI-2108 At ECCO 2026

Palisade Bio, Inc. Appoints Bram Verstockt to Clinical Advisory Board

Recent updates

Palisade Bio Inc Reports Additional Phase 1a/b Data Demonstrating Colon-Targeted Exposure And Sustained IC90 Coverage Supporting Once-Daily Dosing In Ulcerative Colitis

Palisade Bio, Inc., Annual General Meeting, Jun 10, 2026

Price target increased by 7.7% to US$11.13

Palisade Bio, Inc. Reports Positive Topline Data From Phase 1b Clinical Study of PALI-2108 in Fibrostenotic Crohn’s Disease

Palisade Bio, Inc. Reports Rapid Clinical, Histologic and New Mechanistic Colon Tissue RNA Sequencing Data Supporting Targeted Activity of PALI-2108 At ECCO 2026

Palisade Bio, Inc. Appoints Bram Verstockt to Clinical Advisory Board

Palisade Bio, Inc. Announces Clinical Advisory Board Changes

Palisade Bio, Inc. announced that it expects to receive $0.5 million in funding from Crohn's & Colitis Foundation, Inc.

Palisade Bio, Inc. Announces Granting of Japanese Patent Covering Composition of Matter for Lead Product Candidate, PALI-2108

Palisade Bio: Gut Prodrug For IBD With Catalysts

Price target increased by 29% to US$10.33

Palisade Bio, Inc. Appoints Sharon Skare as Vice President, Global Head of Clinical Operations

Palisade Bio Announces First Patients Dosed in Phase 1B Study of Oral First-In-Class PDE4 Inhibitor Prodrug, PALI-2108, for the Treatment of Fibrostenotic Crohn's Disease (FSCD)

Palisade Bio, Inc. has completed a Follow-on Equity Offering in the amount of $120 million.

Palisade Bio, Inc. has filed a Follow-on Equity Offering.

Palisade Bio Reports Positive PALI-2108 Phase 1b Clinical Data

Palisade Bio, Inc., Annual General Meeting, Oct 17, 2025

Palisade Bio, Inc. Receives Health Canada Clearance for Phase 1b Trial of PALI-2108 in Fibrostenotic Crohn's Disease (FSCD)

New major risk - Financial position

Palisade Bio, Inc. Reports 100% Clinical Response in Phase 1b Ulcerative Colitis Cohort with Novel PDE4 Inhibitor, Pali-2108

High number of new and inexperienced directors

New minor risk - Share price stability

Palisade Bio, Inc. Appoints Emil Chuang to Its Board of Directors

Palisade Bio, Inc. has withdrawn its Follow-on Equity Offering.

Palisade Bio, Inc. Reports Positive Phase 1A Results for PALI-2108

Palisade Bio, Inc. has filed a Follow-on Equity Offering.

Palisade Bio, Inc. Presents Positive Preclinical Data Highlighting Potential of PALI-2108 as A Promising Colon-Specific Pde4 Inhibitor for the Treatment of Ulcerative Colitis and Other Inflammatory Bowel Diseases

Palisade Bio Receives Notice from the Nasdaq Stock Market

Palisade Bio, Inc. Completes Dosing in Phase 1a Portion of Ongoing Phase 1a/b Study of PALI-2108

New major risk - Financial position

Palisade Bio, Inc. Commences Dosing in First Ulcerative Colitis Patient Cohort in Ongoing Phase 1A/B Study of PALI-2108

Palisade Bio, Inc. Presents Positive Preclinical Data of PALI-2108 for the Treatment of Ulcerative Colitis

Palisade Bio, Inc. Completes All Five SAD Cohorts and Advances to MAD Cohorts of Phase 1a/b Study of PALI-2108 for Treatment of Ulcerative Colitis

High number of new and inexperienced directors

Palisade Bio, Inc. Appoints Brian G. Feagan to its Clinical Advisory Board

Palisade Bio, Inc. Announces Preliminary Data from Phase 1 Clinical Study of PALI-2108 for the Treatment of Moderate-To-Severe Ulcerative Colitis Is to Be Safe and Well Tolerated in Treated Subjects

Palisade Bio to Present Preclinical Results for PALI-2108 Demonstrating Engagement of Key Fibrotic Pathways of Crohn's Disease and Ulcerative Colitis

Price target increased by 33% to US$45.00

Palisade Bio Announces First Subject Dosed in Phase 1 Clinical Study of PALI-2108 for the Treatment of Moderate-to-Severe Ulcerative Colitis (UC)

Palisade Bio, Inc. Announces Positive Data from Two Ex Vivo Translational Studies of PALI-2108 for the Treatment of Ulcerative Colitis

Palisade Bio, Inc. has filed a Follow-on Equity Offering.

Palisade Bio Cleared by Health Canada to Commence Phase 1 Clinical Study for Lead Program, PALI-2108 for the Treatment of Ulcerative Colitis

Palisade Bio Reports Data Demonstrating PDE4B Expression in Patient Cohorts Could Be Utilized as a Potential Marker for Patient Stratification

New major risk - Financial position

Palisade Bio, Inc. Selects Dose for Upcoming Phase 1 Clinical Study of PALI-2108 for Ulcerative Colitis

Palisade Bio, Inc. Successfully Completes Microbiome Study Confirming Bacterial Enzymes for Local Bioactivation of Leading Product Candidate, PALI-2108

Palisade Bio, Inc. Announces Successful Completion of First GMP Manufacturing of PALI-2108 Drug Substance and Engineering Batches of Drug Product

Palisade Bio, Inc., Annual General Meeting, Jul 08, 2024

Palisade Bio, Inc. Announces Presentation of Positive Preclinical Data from PALI-2108

Price target decreased by 33% to US$22.50

Palisade Bio, Inc. announced that it has received $3.999943 million in funding

Palisade Bio, Inc. Appoints Margery Fischbein to Its Board of Directors

Palisade Bio, Inc. announced that it expects to receive $3.999996 million in funding

Palisade Bio’s Lead Product Candidate, PALI-2108 Demonstrates Potent Anti-Inflammatory Effects in Ex-Vivo Study of Whole Blood Samples Challenged with Pro-Inflammatory Lipopolysaccharide (LPS)

Palisade Bio Successfully Demonstrates Bioactivation of PALI-2108 In Ex-Vivo Study of Normal Healthy and Ulcerative Colitis Patients’ Stool

Palisade Bio, Inc. Receives Notice from the Listing Qualifications Department of the Nasdaq Stock Market LLC Regarding Non-Compliance with the Audit Committee Requirements

Palisade Bio, Inc. Announces Advisory Board Appointments

New major risk - Share price stability

Palisade Bio, Inc. has withdrawn its Follow-on Equity Offering in the amount of $5 million.

Palisade Bio, Inc. has filed a Follow-on Equity Offering in the amount of $5 million.

New major risk - Revenue and earnings growth

Price target decreased by 81% to US$3.00

Palisade Bio Receives Non-Compliance Notice from Nasdaq

Palisade Bio, Inc. has completed a Follow-on Equity Offering in the amount of $1.965094 million.