OSE Immunotherapeutics (ORPO.F) Stock Overview
A clinical-stage biotechnology company, develops immunotherapies in the areas of immune-oncology and immune-inflammation in France and internationally. More details
| Snowflake Score | |
|---|---|
| Valuation | 0/6 |
| Future Growth | 5/6 |
| Past Performance | 0/6 |
| Financial Health | 3/6 |
| Dividends | 0/6 |
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OSE Immunotherapeutics SA Competitors
Price History & Performance
| Historical stock prices | |
|---|---|
| Current Share Price | €4.43 |
| 52 Week High | €4.43 |
| 52 Week Low | €4.43 |
| Beta | 0.83 |
| 1 Month Change | 0% |
| 3 Month Change | n/a |
| 1 Year Change | n/a |
| 3 Year Change | n/a |
| 5 Year Change | n/a |
| Change since IPO | -6.89% |
Recent News & Updates
Recent updates
Shareholder Returns
| ORPO.F | US Biotechs | US Market | |
|---|---|---|---|
| 7D | 0% | -5.3% | -1.0% |
| 1Y | n/a | 37.0% | 14.1% |
Return vs Industry: Insufficient data to determine how ORPO.F performed against the US Biotechs industry.
Return vs Market: Insufficient data to determine how ORPO.F performed against the US Market.
Price Volatility
| ORPO.F volatility | |
|---|---|
| ORPO.F Average Weekly Movement | n/a |
| Biotechs Industry Average Movement | 9.6% |
| Market Average Movement | 6.9% |
| 10% most volatile stocks in US Market | 15.3% |
| 10% least volatile stocks in US Market | 2.9% |
Stable Share Price: ORPO.F's share price has been volatile over the past 3 months compared to the US market.
Volatility Over Time: Insufficient data to determine ORPO.F's volatility change over the past year.
About the Company
| Founded | Employees | CEO | Website |
|---|---|---|---|
| 2012 | 64 | Marc Le Bozec | www.ose-immuno.com |
OSE Immunotherapeutics SA, a clinical-stage biotechnology company, develops immunotherapies in the areas of immune-oncology and immune-inflammation in France and internationally. The company’s products include Tedopi that is in Phase III clinical trial for the treatment of non-small cell lung cancer, as well as in Phase II clinical trial to pancreatic and ovarian cancer; OSE-279, which is in a Phase I/II clinical trial in patients with advanced solid tumors or lymphomas; OSE-127, a humanized monoclonal antibody that is in Phase II clinical trial for the treatment of ulcerative colitis, as well as Sjögren’s Syndrome; and FR104, which is in Phase I clinical trial for the treatment of rheumatoid arthritis. The company is also developing BI 765063, which is in Phase I clinical trial to treat solid tumors; ABBV-230, an agonist antibody against ChemR23 to resolve chronic inflammation; and CLEC-1, a therapeutic target in immune-oncology and identified monoclonal antibody antagonists; and BiCKI, a new technology of bispecific checkpoint inhibitors targeting the PD1 receptor and other innovative targets.
OSE Immunotherapeutics SA Fundamentals Summary
| ORPO.F fundamental statistics | |
|---|---|
| Market cap | US$86.93m |
| Earnings (TTM) | -US$43.67m |
| Revenue (TTM) | US$3.12m |
Is ORPO.F overvalued?
See Fair Value and valuation analysisEarnings & Revenue
| ORPO.F income statement (TTM) | |
|---|---|
| Revenue | €2.69m |
| Cost of Revenue | €304.00k |
| Gross Profit | €2.39m |
| Other Expenses | €40.08m |
| Earnings | -€37.69m |
Last Reported Earnings
Dec 31, 2025
Next Earnings Date
Sep 28, 2026
| Earnings per share (EPS) | -1.60 |
| Gross Margin | 88.70% |
| Net Profit Margin | -1,400.56% |
| Debt/Equity Ratio | 117.9% |
How did ORPO.F perform over the long term?
See historical performance and comparisonCompany Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2026/08/30 01:08 |
| End of Day Share Price | 2026/06/02 00:00 |
| Earnings | 2025/12/31 |
| Annual Earnings | 2025/12/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
| |
| Analyst Consensus Estimates | +3 years |
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| Market Prices | 30 years |
| |
| Ownership | 10 years |
| |
| Management | 10 years |
| |
| Key Developments | 10 years |
|
* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.
Learn about the who designed and built the Simply Wall St analysis model.
Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
OSE Immunotherapeutics SA is covered by 4 analysts. 4 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| David Seynnaeve | Degroof Petercam |
| Jyoti Prakash | Edison Investment Research |
| Martial Descoutures | ODDO BHF Corporate & Markets |