Appili Therapeutics (APLI.F) Stock Overview
A biopharmaceutical company, focuses on the acquisition and development of novel medicines for unmet needs in infectious disease in Canada. More details
| Snowflake Score | |
|---|---|
| Valuation | 0/6 |
| Future Growth | 0/6 |
| Past Performance | 0/6 |
| Financial Health | 2/6 |
| Dividends | 0/6 |
APLI.F Community Fair Values
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Looking to be second time lucky with a game-changing new product
Key Takeaways Unicycive has successfully completed clinical development of its lead asset, Oxylanthanum Carbonate (OLC). OLC has been designed to improve on current phosphate binders by offering better efficacy, fewer pills, and improved tolerability over alternative treatments for hyperphosphatemia chronic kidney disease patients on dialysis.Read more

Appili Therapeutics Inc. Competitors
Price History & Performance
| Historical stock prices | |
|---|---|
| Current Share Price | CA$0.014 |
| 52 Week High | CA$0.031 |
| 52 Week Low | CA$0.0089 |
| Beta | 0.066 |
| 1 Month Change | -4.70% |
| 3 Month Change | -14.15% |
| 1 Year Change | -44.31% |
| 3 Year Change | -54.49% |
| 5 Year Change | -98.32% |
| Change since IPO | -98.93% |
Recent News & Updates
Recent updates
Shareholder Returns
| APLI.F | US Pharmaceuticals | US Market | |
|---|---|---|---|
| 7D | 0% | -1.3% | 1.0% |
| 1Y | -44.3% | 25.5% | 14.6% |
Return vs Industry: APLI.F underperformed the US Pharmaceuticals industry which returned 25.5% over the past year.
Return vs Market: APLI.F underperformed the US Market which returned 14.6% over the past year.
Price Volatility
| APLI.F volatility | |
|---|---|
| APLI.F Average Weekly Movement | n/a |
| Pharmaceuticals Industry Average Movement | 9.3% |
| Market Average Movement | 6.4% |
| 10% most volatile stocks in US Market | 16.0% |
| 10% least volatile stocks in US Market | 3.0% |
Stable Share Price: APLI.F's share price has been volatile over the past 3 months compared to the US market.
Volatility Over Time: Insufficient data to determine APLI.F's volatility change over the past year.
About the Company
| Founded | Employees | CEO | Website |
|---|---|---|---|
| 2015 | 7 | Don Cilla | appilitherapeutics.com |
Appili Therapeutics Inc., a biopharmaceutical company, focuses on the acquisition and development of novel medicines for unmet needs in infectious disease in Canada. Its anti-infective portfolio includes ATI-1501, a liquid oral taste-masked reformulation of the antibiotic metronidazole to treat anaerobic bacterial, protozoal, and parasitic infections; ATI-1801, a novel topical formulation of paromomycin for the treatment of cutaneous leishmaniasis; and ATI-1701, a live-attenuated vaccine for the treatment of francisella tularensis. The company was incorporated in 2015 and is headquartered in Halifax, Canada.
Appili Therapeutics Inc. Fundamentals Summary
| APLI.F fundamental statistics | |
|---|---|
| Market cap | US$1.93m |
| Earnings (TTM) | -US$2.17m |
| Revenue (TTM) | US$150.77k |
Is APLI.F overvalued?
See Fair Value and valuation analysisEarnings & Revenue
| APLI.F income statement (TTM) | |
|---|---|
| Revenue | CA$206.31k |
| Cost of Revenue | CA$0 |
| Gross Profit | CA$206.31k |
| Other Expenses | CA$3.17m |
| Earnings | -CA$2.96m |
Last Reported Earnings
Dec 31, 2025
Next Earnings Date
n/a
| Earnings per share (EPS) | -0.022 |
| Gross Margin | 100.00% |
| Net Profit Margin | -1,436.49% |
| Debt/Equity Ratio | -76.0% |
How did APLI.F perform over the long term?
See historical performance and comparisonCompany Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2026/02/22 14:35 |
| End of Day Share Price | 2026/02/13 00:00 |
| Earnings | 2025/12/31 |
| Annual Earnings | 2025/03/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
| |
| Analyst Consensus Estimates | +3 years |
|
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| Market Prices | 30 years |
| |
| Ownership | 10 years |
| |
| Management | 10 years |
| |
| Key Developments | 10 years |
|
* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.
Learn about the world class team who designed and built the Simply Wall St analysis model.
Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
Appili Therapeutics Inc. is covered by 2 analysts. 0 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| Douglas Loe | Leede Financial Inc |
| Andre Uddin | Research Capital Corporation |
