Stock Analysis

Tempus AI (TEM): Assessing Valuation Following Analyst Optimism on Growth Drivers and Precision Medicine Collaboration

Tempus AI (TEM) is drawing new attention after analysts highlighted strong momentum from its Ambry acquisition, advances in rare disease testing, and a new collaboration focused on precision medicine. Investors are watching closely as these factors develop.

See our latest analysis for Tempus AI.

Tempus AI’s share price has surged more than 127% year to date as interest in healthcare innovation grows, even with some volatility along the way. Recent momentum from its Ambry acquisition and new precision medicine partnerships suggests investors see further room for long-term growth.

If you’re curious about what other healthcare innovators are capturing attention, it’s a great moment to discover See the full list for free.

Given these new catalysts and robust growth drivers, the central question becomes whether Tempus AI’s current share price still presents a buying opportunity, or if the market is already pricing in the company’s anticipated growth ahead.

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Most Popular Narrative: 14.4% Undervalued

Tempus AI’s latest fair value estimate stands at $91 per share, significantly higher than the most recent closing price of $77.93. This prominent narrative suggests that the market may not have fully reflected all anticipated growth drivers and potential profitability improvements in its current valuation.

Robust discipline in investment and operating leverage, as evidenced by rapid revenue growth paired with improving adjusted EBITDA and gross margins, supports near-term profitability and strengthens the case for long-term scalable earnings expansion. Secular increases in the adoption of AI and data analytics in drug development, along with broadening regulatory clarity for digital diagnostics, indicate that Tempus AI is uniquely positioned to capture a growing share of healthcare spending. This is expected to directly increase revenue and enhance future opportunities for margin improvement.

Read the complete narrative.

Can a wave of AI-driven margins and long-term revenue acceleration justify this notable valuation? The narrative revolves around whether meaningful improvements in profit and growth will reshape its financial outlook. Want to see the specifics fueling the analysts’ optimism? Unlock the detailed forecasts that support these figures.

Result: Fair Value of $91 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, intensifying competition and looming reimbursement uncertainties could still test the durability of Tempus AI’s growth narrative in the coming years.

Find out about the key risks to this Tempus AI narrative.

Another View: What Do Multiples Say?

While some models point to Tempus AI being undervalued, a closer look at its price-to-sales ratio tells a different story. At 12.5x, it is significantly higher than both the industry average of 3.7x and the peer average of 5.5x, as well as the fair ratio of 9.3x. This raises the possibility that investors have already priced in plenty of optimism, leaving less room for upside based on fundamentals. Could this high valuation signal a riskier entry point?

See what the numbers say about this price — find out in our valuation breakdown.

NasdaqGS:TEM PS Ratio as at Nov 2025
NasdaqGS:TEM PS Ratio as at Nov 2025

Build Your Own Tempus AI Narrative

If you want to dig into the numbers and shape your own perspective, it's easy to build a custom narrative in just a few minutes. Do it your way

A great starting point for your Tempus AI research is our analysis highlighting 2 key rewards and 2 important warning signs that could impact your investment decision.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

Valuation is complex, but we're here to simplify it.

Discover if Tempus AI might be undervalued or overvalued with our detailed analysis, featuring fair value estimates, potential risks, dividends, insider trades, and its financial condition.

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About NasdaqGS:TEM

Tempus AI

Operates as a healthcare technology company.

Slightly overvalued with limited growth.

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