Scholar Rock Holding Corporation

NasdaqGS:SRRK Stock Report

Market Cap: US$6.0b

Scholar Rock Holding Past Earnings Performance

Past criteria checks 0/6

Scholar Rock Holding's earnings have been declining at an average annual rate of -28.1%, while the Biotechs industry saw earnings growing at 36.2% annually. Revenues have been declining at an average rate of 62.9% per year.

Key information

-28.15%

Earnings growth rate

-0.18%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate-62.86%
Return on equity-148.08%
Net Marginn/a
Last Earnings Update31 Mar 2026

Recent past performance updates

Recent updates

New Narrative Mar 07

Muscle-Targeted SMA Therapies And Global Expansion Will Reshape Long-Term Outlook

Catalysts About Scholar Rock Holding Scholar Rock Holding focuses on developing muscle-targeted therapies for rare and severe neuromuscular diseases, led by its apitegromab program for spinal muscular atrophy and a broader anti myostatin pipeline. What are the underlying business or industry changes driving this perspective?
Seeking Alpha Jan 06

Scholar Rock: Apitegromab's Path Forward Remains Intact, Maintaining Buy Rating

Summary I maintain a buy rating on Scholar Rock, raising my target price to $97, reflecting increased confidence in apitegromab's approval and commercial prospects. FDA setbacks are manufacturing-related, not clinical, with no new efficacy or safety concerns; remediation and a second CDMO are underway. Topline phase 3 data support apitegromab's novel mechanism and broad label potential, materially expanding SRRK's addressable market and pricing power. SRRK's risks include potential further manufacturing delays, regulatory timing uncertainties, and possible capital raises if approval is postponed beyond the 2027 cash runway. Read the full article on Seeking Alpha
Seeking Alpha Apr 17

Scholar Rock: Apitegromab Approval And Obesity Shot Make For Rating Upgrade

Summary Scholar Rock Holding Corporation's lead candidate, apitegromab, has shown promising efficacy in treating SMA and is awaiting FDA and EMA approval, with a potential market launch by late 2025. Apitegromab could achieve blockbuster status with peak revenue potential >$2.5bn, especially based on its ability to build muscle mass in combo with gene therapies like Spinraza and Zolgensma. Scholar Rock's obesity therapy potential with apitegromab and GLP-1 RA combo presents a high-risk, high-reward scenario, with significant upside if Phase 2 data is positive. Despite financial challenges and potential dilution, I upgrade SRRK stock to a "Buy" due to its promising pipeline and undervalued stock price at $30. Read the full article on Seeking Alpha
Seeking Alpha Jan 30

Scholar Rock: More Than Just An SMA Biotech With Q2 2025 Obesity Treatment Data

Summary Scholar Rock submitted its BLA of apitegromab for the treatment of patients with Spinal Muscular Atrophy with a request for Priority Review to be given. Apitegromab is being explored in the phase 2 proof-of-concept EMBRAZE study, given alongside GLP-1 drugs to treat patients with obesity; Data from this trial is expected in Q2 of 2025. Positive data from the phase 2 EMBRAZE study would lead to IND of SRK-439 in Q3 of 2025 to target obesity and other cardiometabolic disorders. The global obesity drugs market is expected to reach $200 billion by 2031. Read the full article on Seeking Alpha
Seeking Alpha Dec 24

Scholar Rock: Likely Approval In SMA Plus Obesity Data In 2025 Intrigue, But Price Too High

Summary Scholar Rock's lead candidate, apitegromab, showed promising Phase 3 results in SMA, boosting shares by over 325%, with plans for regulatory submissions in the US and EU. Despite positive data, Scholar Rock faces financial challenges, including significant net losses and limited cash, suggesting potential future fundraisings. The company is exploring apitegromab's potential in obesity treatment, with a Phase 2 study underway, in combo with a GLP-1 agonist drug - results are expected in Q2 2025. Given current valuation and financial risks, I recommend a "Hold" rating, with potential buying opportunities post-approval or pre-obesity study results if the share price dips below $30, I'd suggest. Read the full article on Seeking Alpha
Seeking Alpha Oct 07

Scholar Rock: SMA Program Strides Forward With Positive Clinical Data

Summary Apitegromab met the primary endpoint in its phase 3 SAPPHIRE study for spinal muscular atrophy, setting up BLA & MAA filings in Q1 2025. Apitegromab is the first treatment targeting muscle fiber atrophy in SMA, potentially changing the standard of care and offering a competitive edge. Scholar Rock also has apitegromab being explored in a phase 2 study for obesity, with clinical data expected in Q2 2025, presenting another catalyst. The spinal muscular atrophy market in the 7 major markets [7MM] is expected to reach $13 billion by 2034. Read the full article on Seeking Alpha
Seeking Alpha Jan 12

Scholar Rock: Solid Data And Good Prospects

Summary Scholar Rock's stock price has increased from $6 to $16, indicating increased market interest. Scholar Rock develops apitegromab, a targeted therapy for Spinal Muscular Atrophy (SMA) that inhibits myostatin activation. Phase 2 data shows sustained improvement in motor function for non-ambulatory SMA patients receiving apitegromab. Phase 3 data expected in 4Q 2024. Read the full article on Seeking Alpha

Revenue & Expenses Breakdown

How Scholar Rock Holding makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:SRRK Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 260-4091980
31 Dec 250-3781760
30 Sep 250-3531500
30 Jun 250-3161130
31 Mar 250-264810
31 Dec 240-246680
30 Sep 240-226620
30 Jun 240-204590
31 Mar 240-183540
31 Dec 230-166490
30 Sep 230-159470
30 Jun 230-160440
31 Mar 230-166430
31 Dec 2233-135430
30 Sep 2237-131430
30 Jun 2243-125430
31 Mar 2247-112420
31 Dec 2119-132400
30 Sep 2118-122380
30 Jun 2116-109350
31 Mar 2115-97320
31 Dec 2015-86280
30 Sep 2020-71260
30 Jun 2021-64240
31 Mar 2022-57230
31 Dec 1920-51210
30 Sep 1913-54200
30 Jun 198-49170
31 Mar 193-51160
31 Dec 180-49140
30 Sep 180-43110
30 Jun 180-3890
31 Mar 180-2960
31 Dec 170-2550
31 Dec 160-1640

Quality Earnings: SRRK is currently unprofitable.

Growing Profit Margin: SRRK is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: SRRK is unprofitable, and losses have increased over the past 5 years at a rate of 28.1% per year.

Accelerating Growth: Unable to compare SRRK's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: SRRK is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (54.5%).


Return on Equity

High ROE: SRRK has a negative Return on Equity (-148.08%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/29 12:11
End of Day Share Price 2026/05/29 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Scholar Rock Holding Corporation is covered by 24 analysts. 16 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Madhu KumarBaird
Etzer DaroutBarclays
Evan SeigermanBMO Capital Markets Equity Research