Stock Analysis

Soleno Therapeutics (SLNO) Is Down 8.9% After Short Seller Targets VYKAT XR Safety and Market Potential – Has The Bull Case Changed?

  • Rosen Law Firm recently announced an investigation on behalf of Soleno Therapeutics shareholders, following allegations raised by Scorpion Capital’s short report about the safety and commercial prospects of Soleno’s Prader-Willi syndrome treatment, VYKAT XR.
  • The initiation of a potential class action highlights growing legal scrutiny and calls attention to material concerns over Soleno’s core therapeutic pipeline.
  • We’ll explore how the negative attention around VYKAT XR’s safety and market outlook is impacting Soleno Therapeutics’ investment narrative.

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What Is Soleno Therapeutics' Investment Narrative?

For anyone considering Soleno Therapeutics, the fundamental belief hinges on VYKAT XR’s ability to secure and sustain a foothold as a safe and effective treatment for Prader-Willi syndrome, alongside prospects for regulatory traction and commercial adoption. Until now, key short-term catalysts have included the recent FDA approval, European filing, and positive efficacy data, with substantial capital raised to support the launch. However, the emergence of a class action investigation and new scrutiny around VYKAT XR’s safety and market outlook introduce immediate uncertainties that could shift both risks and near-term catalysts. The significant drop in share price since the short report signals that the market is weighing these legal and reputational risks seriously, possibly slowing the momentum Soleno had been building. Investors now have to consider that developments around litigation and ongoing safety concerns may directly impact expectations for growth and value recovery, at least in the short run. On the other hand, what does this mean for the launch and sales expectations?

Despite retreating, Soleno Therapeutics' shares might still be trading above their fair value and there could be some more downside. Discover how much.

Exploring Other Perspectives

SLNO Community Fair Values as at Oct 2025
SLNO Community Fair Values as at Oct 2025
The Simply Wall St Community’s three fair value forecasts for Soleno Therapeutics span a range from US$46.90 to a very large US$469.02 per share, with estimates clustered across several bands. This wide spread highlights how sharply opinions differ, especially now that new legal risks may shift market sentiment and future prospects. Explore more insights and contrasting views from other community analysts.

Explore 3 other fair value estimates on Soleno Therapeutics - why the stock might be worth 21% less than the current price!

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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About NasdaqCM:SLNO

Soleno Therapeutics

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

High growth potential with adequate balance sheet.

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