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Skye Bioscience, Inc.NasdaqGM:SKYE Stock Report

Market Cap US$30.3m
Share Price
US$0.86
US$8.25
89.5% undervalued intrinsic discount
1Y-57.9%
7D-0.8%
Portfolio Value
View

Skye Bioscience, Inc.

NasdaqGM:SKYE Stock Report

Market Cap: US$30.3m

Skye Bioscience (SKYE) Stock Overview

A clinical-stage biotechnology company, focuses on developing molecules that modulate G-protein-coupled receptors (GPCRs) to treat obesity, overweight, and metabolic diseases. More details

SKYE fundamental analysis
Snowflake Score
Valuation2/6
Future Growth0/6
Past Performance0/6
Financial Health4/6
Dividends0/6

SKYE Community Fair Values

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See what 9 others think this stock is worth. Follow their fair value or set your own to get alerts.

Skye Bioscience, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Skye Bioscience
Historical stock prices
Current Share PriceUS$0.86
52 Week HighUS$5.75
52 Week LowUS$0.57
Beta3.03
1 Month Change19.82%
3 Month Change19.77%
1 Year Change-57.92%
3 Year Change-78.43%
5 Year Change-96.86%
Change since IPO-99.90%

Recent News & Updates

Analysis Article Feb 04

Here's Why Skye Bioscience (NASDAQ:SKYE) Must Use Its Cash Wisely

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...

Recent updates

Analysis Article Feb 04

Here's Why Skye Bioscience (NASDAQ:SKYE) Must Use Its Cash Wisely

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...
Seeking Alpha Oct 01

Skye Bioscience: Promising Nimacimab Data Supports Buy Rating

Summary Skye Bioscience is rated Buy, driven by nimacimab’s strong safety, durable weight-loss profile, and upcoming Phase 2a results. SKYE’s nimacimab targets the expanding anti-obesity market, showing potential as monotherapy, combination, or maintenance therapy, with favorable early data. Risks include clinical trial uncertainties, manufacturing reliance, and regulatory scrutiny, but SKYE’s cash runway extends through Q1 2027, supporting key milestones. SKYE trades at a conservative P/B ratio slightly above the industry average, offering potential upside without excessive premium risk in a competitive sector. Read the full article on Seeking Alpha
Analysis Article Sep 06

Is Skye Bioscience (NASDAQ:SKYE) In A Good Position To Invest In Growth?

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article Apr 22

Will Skye Bioscience (NASDAQ:SKYE) Spend Its Cash Wisely?

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...
Seeking Alpha Apr 16

A Weight Loss Drug Candidate Essentially For Free As Skye Bioscience Is Trading At Cash Value

Summary Weight loss drug stocks like Novo Nordisk have dropped significantly lately. This presents potential value opportunities in a market projected to grow to $105 billion by 2035. Skye Bioscience's nimacimab, in Phase 2a trials, shows promise with significant weight loss results in mouse models, making it a speculative but potentially rewarding investment. 26-week results for the Phase 2a are expected in late Q3 or early Q4, so positive catalysts are on the horizon. SKYE currently trades essentially at cash value, meaning investors who buy in today get a weight loss drug candidate essentially for free. Read the full article on Seeking Alpha
Seeking Alpha Dec 10

Skye Bioscience: Nimacimab Targets Safer Weight Loss, Speculative Buy

Summary Skye Bioscience's Nimacimab shows promising Phase 1 safety data and is in Phase 2 trials, potentially revolutionizing obesity treatment with minimal neuropsychiatric side effects. Nimacimab’s large-molecule design avoids neuropsychiatric side effects, a major issue with earlier CB1 inhibitors like rimonabant and monlunabant. The drug’s preclinical evidence suggests fat-specific weight loss, lean muscle preservation, and appetite regulation, positioning it as a competitive alternative to GLP-1 therapies. SKYE seems undervalued, with a market cap of $67.4 million, a P/B ratio of 1.5, and a cash runway of 2.5 years, suggesting significant upside potential. Despite risks related to early-stage IP and low trading volume, SKYE's promising IP and near-term catalysts justify a speculative "Buy" rating. Read the full article on Seeking Alpha
Seeking Alpha Sep 04

Skye: Moving Weight Loss Drugs To The Next Level

Summary Skye Bioscience, Inc. interim data from phase 2 CBbeyondTM study, using nimacimab for the treatment of patients with obesity, is expected Q2 and Q4 of 2025. Experimental arm added into phase 2 CBeyondTM study, which is combining the use of nimacimab with Wegovy for the treatment of patients with obesity. The global obesity drugs market is expected to reach $105 billion in 2030. Several factors differentiate CB1 inhibitor nimacimab compared to other weight loss drugs, such as: Potential for less frequent dosing, less gastrointestinal side effects and long-term dosing for patient compliance. Read the full article on Seeking Alpha
Analysis Article Aug 11

Is Skye Bioscience (NASDAQ:SKYE) Using Debt In A Risky Way?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...

Shareholder Returns

SKYEUS BiotechsUS Market
7D-0.8%1.3%2.2%
1Y-57.9%42.0%31.1%

Return vs Industry: SKYE underperformed the US Biotechs industry which returned 42% over the past year.

Return vs Market: SKYE underperformed the US Market which returned 31.1% over the past year.

Price Volatility

Is SKYE's price volatile compared to industry and market?
SKYE volatility
SKYE Average Weekly Movement11.2%
Biotechs Industry Average Movement10.7%
Market Average Movement7.3%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: SKYE's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: SKYE's weekly volatility has decreased from 17% to 11% over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
n/a12Punit Dhillonskyebioscience.com

Skye Bioscience, Inc., a clinical-stage biotechnology company, focuses on developing molecules that modulate G-protein-coupled receptors (GPCRs) to treat obesity, overweight, and metabolic diseases. Its lead product candidate is nimacimab, a peripherally restricted negative allosteric modulating antibody targeting cannabinoid receptor 1, a key GPCR involved in metabolic regulation. The company was formerly known as Emerald Bioscience, Inc. and changed its name to Skye Bioscience, Inc. in January 2021.

Skye Bioscience, Inc. Fundamentals Summary

How do Skye Bioscience's earnings and revenue compare to its market cap?
SKYE fundamental statistics
Market capUS$30.30m
Earnings (TTM)-US$55.92m
Revenue (TTM)n/a
0.0x
P/S Ratio
-0.5x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
SKYE income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$55.92m
Earnings-US$55.92m

Last Reported Earnings

Dec 31, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-1.59
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did SKYE perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/11 18:11
End of Day Share Price 2026/05/08 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Skye Bioscience, Inc. is covered by 9 analysts. 8 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Kristen KluskaCantor Fitzgerald & Co.
Jonathan WollebenCitizens JMP Securities, LLC
Gum-Ming LoweCraig-Hallum Capital Group LLC