Skye Bioscience, Inc.

NasdaqGM:SKYE Stock Report

Market Cap: US$30.3m

Skye Bioscience Past Earnings Performance

Past criteria checks 0/6

Skye Bioscience's earnings have been declining at an average annual rate of -37.3%, while the Biotechs industry saw earnings growing at 30.5% annually.

Key information

-37.33%

Earnings growth rate

28.07%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth raten/a
Return on equity-279.29%
Net Marginn/a
Last Earnings Update31 Dec 2025

Recent past performance updates

Recent updates

Analysis Article • Feb 04

Here's Why Skye Bioscience (NASDAQ:SKYE) Must Use Its Cash Wisely

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...
Seeking Alpha • Oct 01

Skye Bioscience: Promising Nimacimab Data Supports Buy Rating

Summary Skye Bioscience is rated Buy, driven by nimacimab’s strong safety, durable weight-loss profile, and upcoming Phase 2a results. SKYE’s nimacimab targets the expanding anti-obesity market, showing potential as monotherapy, combination, or maintenance therapy, with favorable early data. Risks include clinical trial uncertainties, manufacturing reliance, and regulatory scrutiny, but SKYE’s cash runway extends through Q1 2027, supporting key milestones. SKYE trades at a conservative P/B ratio slightly above the industry average, offering potential upside without excessive premium risk in a competitive sector. Read the full article on Seeking Alpha
Analysis Article • Sep 06

Is Skye Bioscience (NASDAQ:SKYE) In A Good Position To Invest In Growth?

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article • Apr 22

Will Skye Bioscience (NASDAQ:SKYE) Spend Its Cash Wisely?

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...
Seeking Alpha • Apr 16

A Weight Loss Drug Candidate Essentially For Free As Skye Bioscience Is Trading At Cash Value

Summary Weight loss drug stocks like Novo Nordisk have dropped significantly lately. This presents potential value opportunities in a market projected to grow to $105 billion by 2035. Skye Bioscience's nimacimab, in Phase 2a trials, shows promise with significant weight loss results in mouse models, making it a speculative but potentially rewarding investment. 26-week results for the Phase 2a are expected in late Q3 or early Q4, so positive catalysts are on the horizon. SKYE currently trades essentially at cash value, meaning investors who buy in today get a weight loss drug candidate essentially for free. Read the full article on Seeking Alpha
Seeking Alpha • Dec 10

Skye Bioscience: Nimacimab Targets Safer Weight Loss, Speculative Buy

Summary Skye Bioscience's Nimacimab shows promising Phase 1 safety data and is in Phase 2 trials, potentially revolutionizing obesity treatment with minimal neuropsychiatric side effects. Nimacimab’s large-molecule design avoids neuropsychiatric side effects, a major issue with earlier CB1 inhibitors like rimonabant and monlunabant. The drug’s preclinical evidence suggests fat-specific weight loss, lean muscle preservation, and appetite regulation, positioning it as a competitive alternative to GLP-1 therapies. SKYE seems undervalued, with a market cap of $67.4 million, a P/B ratio of 1.5, and a cash runway of 2.5 years, suggesting significant upside potential. Despite risks related to early-stage IP and low trading volume, SKYE's promising IP and near-term catalysts justify a speculative "Buy" rating. Read the full article on Seeking Alpha
Seeking Alpha • Sep 04

Skye: Moving Weight Loss Drugs To The Next Level

Summary Skye Bioscience, Inc. interim data from phase 2 CBbeyondTM study, using nimacimab for the treatment of patients with obesity, is expected Q2 and Q4 of 2025. Experimental arm added into phase 2 CBeyondTM study, which is combining the use of nimacimab with Wegovy for the treatment of patients with obesity. The global obesity drugs market is expected to reach $105 billion in 2030. Several factors differentiate CB1 inhibitor nimacimab compared to other weight loss drugs, such as: Potential for less frequent dosing, less gastrointestinal side effects and long-term dosing for patient compliance. Read the full article on Seeking Alpha
Analysis Article • Aug 11

Is Skye Bioscience (NASDAQ:SKYE) Using Debt In A Risky Way?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...

Revenue & Expenses Breakdown

How Skye Bioscience makes and spends money. Based on latest reported earnings, on an LTM basis.

Earnings and Revenue History

NasdaqGM:SKYE Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Dec 250-561642
30 Sep 250-511539
30 Jun 250-421134
31 Mar 250-331224
31 Dec 240-271119
30 Sep 240-211113
30 Jun 240-42139
31 Mar 240-37107
31 Dec 230-3886
30 Sep 230-43136
30 Jun 230-21126
31 Mar 230-22136
31 Dec 220-19126
30 Sep 220-1266
30 Jun 220-1164
31 Mar 220-954
31 Dec 210-953
30 Sep 210-852
30 Jun 210-742
31 Mar 210-642
31 Dec 200-742
30 Sep 200052
30 Jun 200-442
31 Mar 2001353
31 Dec 190142
30 Sep 190-1042
30 Jun 190-741
31 Mar 190-2641
31 Dec 180-1940
30 Sep 180-1440
30 Jun 180-1240
31 Mar 180-1040
31 Dec 170-440
30 Sep 170-540
30 Jun 170-540
31 Mar 170-441
31 Dec 160-441
30 Sep 160-341
30 Jun 160-341
31 Mar 160-640
31 Dec 150-540
30 Sep 150-650

Quality Earnings: SKYE is currently unprofitable.

Growing Profit Margin: SKYE is currently unprofitable.

Free Cash Flow vs Earnings Analysis

Past Earnings Growth Analysis

Earnings Trend: SKYE is unprofitable, and losses have increased over the past 5 years at a rate of 37.3% per year.

Accelerating Growth: Unable to compare SKYE's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: SKYE is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (43%).

Return on Equity

High ROE: SKYE has a negative Return on Equity (-279.29%), as it is currently unprofitable.

Return on Assets

Return on Capital Employed

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/11 18:11
End of Day Share Price 2026/05/08 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Skye Bioscience, Inc. is covered by 9 analysts. 8 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Kristen KluskaCantor Fitzgerald & Co.
Jonathan WollebenCitizens JMP Securities, LLC
Gum-Ming LoweCraig-Hallum Capital Group LLC