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Cartesian Therapeutics, Inc.NasdaqGM:RNAC Stock Report

Market Cap US$254.2m
Share Price
US$8.53
US$35.57
76.0% undervalued intrinsic discount
1Y-18.3%
7D23.1%
Portfolio Value
View

Cartesian Therapeutics, Inc.

NasdaqGM:RNAC Stock Report

Market Cap: US$254.2m

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Cartesian Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Cartesian Therapeutics
Historical stock prices
Current Share PriceUS$8.53
52 Week HighUS$15.57
52 Week LowUS$5.60
Beta0.56
1 Month Change42.64%
3 Month Change31.84%
1 Year Change-18.30%
3 Year Changen/a
5 Year Changen/a
Change since IPO-73.43%

Recent News & Updates

Seeking Alpha Apr 23

Cartesian Therapeutics: A Phase 3 mRNA CAR-T Bet

Summary Cartesian Therapeutics receives a buy rating, driven by a differentiated mRNA CAR-T approach for autoimmune diseases and strong insider/institutional support. RNAC’s lead asset, Descartes-08, demonstrated a 7.1-point MG-ADL reduction at 12 months in Phase 2b, surpassing current biologics in durability and efficacy. The ongoing Phase 3 AURORA trial, with FDA SPA agreement and 100 patients, is a pivotal binary catalyst; $126.9M cash runway extends into mid-2027. RNAC’s valuation reflects deep discount to potential, but risks include Phase 3 failure, dilution, and competitive threats from both established and emerging CAR-T players. Read the full article on Seeking Alpha
Analysis Article Jan 31

Will Cartesian Therapeutics (NASDAQ:RNAC) Spend Its Cash Wisely?

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...

Recent updates

Seeking Alpha Apr 23

Cartesian Therapeutics: A Phase 3 mRNA CAR-T Bet

Summary Cartesian Therapeutics receives a buy rating, driven by a differentiated mRNA CAR-T approach for autoimmune diseases and strong insider/institutional support. RNAC’s lead asset, Descartes-08, demonstrated a 7.1-point MG-ADL reduction at 12 months in Phase 2b, surpassing current biologics in durability and efficacy. The ongoing Phase 3 AURORA trial, with FDA SPA agreement and 100 patients, is a pivotal binary catalyst; $126.9M cash runway extends into mid-2027. RNAC’s valuation reflects deep discount to potential, but risks include Phase 3 failure, dilution, and competitive threats from both established and emerging CAR-T players. Read the full article on Seeking Alpha
Analysis Article Jan 31

Will Cartesian Therapeutics (NASDAQ:RNAC) Spend Its Cash Wisely?

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Analysis Article Oct 04

We Think Cartesian Therapeutics (NASDAQ:RNAC) Can Afford To Drive Business Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Analysis Article May 04

Subdued Growth No Barrier To Cartesian Therapeutics, Inc. (NASDAQ:RNAC) With Shares Advancing 27%

Cartesian Therapeutics, Inc. ( NASDAQ:RNAC ) shareholders are no doubt pleased to see that the share price has bounced...
Analysis Article Mar 18

Cartesian Therapeutics, Inc.'s (NASDAQ:RNAC) Popularity With Investors Under Threat As Stock Sinks 27%

Cartesian Therapeutics, Inc. ( NASDAQ:RNAC ) shares have had a horrible month, losing 27% after a relatively good...
Seeking Alpha Jan 17

Cartesian Therapeutics: Need To Wait For More Data For Its Novel mRNA Therapies

Summary Cartesian Therapeutics develops mRNA cell therapies for autoimmune diseases, leveraging three modalities: mRNA CAR-T, mRNA MSC, and mRNA in situ. Lead asset Descartes-08 targets myasthenia gravis, showing promising phase 2 results despite initial data confusion; phase 3 trial starts in H1 2025. RNAC's market cap is $487mn with $219mn in cash, providing a runway of 11–12 quarters; R&D and G&A expenses total $17.9mn. While RNAC's innovative approach is intriguing, the early-stage pipeline and uncharted science pose risks; I prefer to wait for more data. Read the full article on Seeking Alpha
Analysis Article Jan 05

Risks Still Elevated At These Prices As Cartesian Therapeutics, Inc. (NASDAQ:RNAC) Shares Dive 33%

Cartesian Therapeutics, Inc. ( NASDAQ:RNAC ) shares have had a horrible month, losing 33% after a relatively good...
Seeking Alpha Nov 10

Cartesian Therapeutics: Uncertainty Remains

Summary Cartesian Therapeutics' stock has rebounded sharply recently despite no significant news, driven partly by insider buying after a disappointing Phase 2b trial for Descartes-08 in myasthenia gravis. The company leverages its RNA Armory platform for mRNA cell therapies, focusing on autoimmune diseases, with Descartes-08 and Descartes-15 as its main assets. Descartes-08 showed mixed results in Phase 2b for MG, raising concerns due to endpoint changes and trial anomalies, yet plans continue for a pivotal trial in 2025. An analysis of Cartesian Therapeutics follows in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha Sep 17

Cartesian Therapeutics Seems A 'Strong Buy' After Positive Phase 2 Results

Summary Cartesian Therapeutics, Inc.'s Descartes-08 mRNA CAR-T therapy shows promising Phase 2 results for myasthenia gravis without preconditioning chemotherapy. The company's RNA Armory platform enables precise, temporary cell modulation, reducing long-term side effects and avoiding genomic integration. Descartes-08 has received FDA Orphan and RMAT designations, with a Phase 3 trial expected to begin by the end of 2024. Cartesian Therapeutics has a strong cash position after a $130 million equity raise, extending its runway to support upcoming trials. I believe Cartesian Therapeutics is a strong buy due to its potential to tap into large markets if Phase 3 trials succeed. Read the full article on Seeking Alpha
Seeking Alpha Jul 02

Cartesian: Further Value To Be Unlocked After Positive MG Treatment Data

Summary Cartesian Therapeutics, Inc. achieved positive results from the phase 2b study using Descartes-08 for the treatment of patients with myasthenia gravis; the End of phase 2 meeting with the FDA is expected by the end of 2024. The global market for generalized myasthenia gravis is projected to reach $7.5 billion by 2031. A soon-to-be-initiated phase 2 basket study would explore other autoimmune disorder indications for Descartes-08; The global autoimmune disease therapeutics market is expected to reach $123.5 billion by 2033. Descartes-15 is a next-generation anti-BCMA mRNA CAR-T being developed for the treatment of patients with multiple myeloma. Read the full article on Seeking Alpha

Shareholder Returns

RNACUS BiotechsUS Market
7D23.1%0.1%2.6%
1Y-18.3%35.5%26.2%

Return vs Industry: RNAC underperformed the US Biotechs industry which returned 42% over the past year.

Return vs Market: RNAC underperformed the US Market which returned 31.1% over the past year.

Price Volatility

Is RNAC's price volatile compared to industry and market?
RNAC volatility
RNAC Average Weekly Movement14.3%
Biotechs Industry Average Movement10.7%
Market Average Movement7.2%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: RNAC's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: RNAC's weekly volatility (14%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
n/a75Carsten Brunnwww.cartesiantherapeutics.com

Cartesian Therapeutics, Inc., a clinical-stage biotechnology company, provides mRNA cell therapies for the treatment of autoimmune diseases. The company’s lead product candidate is Descartes-08, an autologous mRNA chimeric antigen receptor T-cell cell therapy (CAR-T) directed against the B cell maturation antigen (BCMA), which is in Phase 2b clinical trials for the treatment of autoimmune diseases, generalized myasthenia gravis, and systemic lupus erythematosus, as well as rare pediatric disease designation for the treatment of juvenile dermatomyositis. It is also developing Descartes-15, which is in phase 1 trials, an autologous autologous B cell maturation antigen (BCMA) directed mRNA CAR-T to treat patients with multiple myeloma.

Cartesian Therapeutics, Inc. Fundamentals Summary

How do Cartesian Therapeutics's earnings and revenue compare to its market cap?
RNAC fundamental statistics
Market capUS$254.15m
Earnings (TTM)-US$151.77m
Revenue (TTM)US$1.78m
141.2x
P/S Ratio
-1.7x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
RNAC income statement (TTM)
RevenueUS$1.78m
Cost of RevenueUS$62.82m
Gross Profit-US$61.05m
Other ExpensesUS$90.73m
Earnings-US$151.77m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-5.17
Gross Margin-3,439.32%
Net Profit Margin-8,550.65%
Debt/Equity Ratio0%

How did RNAC perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/11 09:11
End of Day Share Price 2026/05/11 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Cartesian Therapeutics, Inc. is covered by 10 analysts. 8 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Julian HarrisonBTIG
John NewmanCanaccord Genuity
Kristen KluskaCantor Fitzgerald & Co.