Is Progress on Cancer Drug Candidates and Big Pharma Partnerships Altering the Investment Case for ORIC Pharmaceuticals (ORIC)?

Simply Wall St
  • ORIC Pharmaceuticals has attracted attention after advancing its cancer drug candidates, ORIC-114 and ORIC-944, into Phase 1b studies and announcing collaborations with major pharmaceutical firms such as Pfizer, Bayer, and Johnson & Johnson.
  • These partnerships reinforce external confidence in ORIC’s research pipeline and highlight the growing pharmaceutical interest in overcoming cancer treatment resistance.
  • We'll explore how ORIC’s progress with its cancer drug candidates and strong pharma alliances could shape its investment narrative.

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What Is ORIC Pharmaceuticals' Investment Narrative?

For investors considering ORIC Pharmaceuticals, the broader thesis rests on belief in the company’s ability to translate its promising science into successful late-stage drugs targeting cancer resistance. The recent advance of lead candidates ORIC-114 and ORIC-944 into Phase 1b studies, alongside fresh partnerships with pharma heavyweights, potentially brings forward short-term catalysts, mainly new clinical results and potential pipeline expansion opportunities. This could bolster sentiment, given that analyst targets remain well above the current share price. However, it’s not all smooth sailing. ORIC’s losses are still rising, there is no revenue, and forecasts expect continued unprofitability for the next three years. The company’s fundraising and high-profile pharma collaborations help strengthen its case, but any shift in clinical data or regulatory setbacks would remain the biggest risks for now, especially with recent dilution and lack of new board appointments in recent years.
Yet, even with progress in its clinical pipeline, funding risks haven’t disappeared.

Our valuation report here indicates ORIC Pharmaceuticals may be overvalued.

Exploring Other Perspectives

ORIC Earnings & Revenue Growth as at Oct 2025
Eleven fair value estimates from the Simply Wall St Community all converge at US$18.27 per share, hinting at limited diversity in outlook. While consensus is high, ongoing clinical developments and no forecasted revenue show why participants’ views may not capture all potential risks. You can compare these opinions with evolving catalysts and multiple analyst forecasts.

Explore another fair value estimate on ORIC Pharmaceuticals - why the stock might be worth as much as 39% more than the current price!

Build Your Own ORIC Pharmaceuticals Narrative

Disagree with this assessment? Create your own narrative in under 3 minutes - extraordinary investment returns rarely come from following the herd.

  • A great starting point for your ORIC Pharmaceuticals research is our analysis highlighting 4 important warning signs that could impact your investment decision.
  • Our free ORIC Pharmaceuticals research report provides a comprehensive fundamental analysis summarized in a single visual - the Snowflake - making it easy to evaluate ORIC Pharmaceuticals' overall financial health at a glance.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

Valuation is complex, but we're here to simplify it.

Discover if ORIC Pharmaceuticals might be undervalued or overvalued with our detailed analysis, featuring fair value estimates, potential risks, dividends, insider trades, and its financial condition.

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