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Neumora Therapeutics, Inc.NasdaqGS:NMRA Stock Report

Market Cap US$305.1m
Share Price
US$1.72
US$8.91
80.7% undervalued intrinsic discount
1Y127.9%
7D-3.4%
Portfolio Value
View

Neumora Therapeutics, Inc.

NasdaqGS:NMRA Stock Report

Market Cap: US$305.1m

Neumora Therapeutics (NMRA) Stock Overview

A clinical-stage biopharmaceutical company, engages in developing therapeutic treatments for brain diseases, neuropsychiatric disorders, and neurodegenerative diseases in the United States. More details

NMRA fundamental analysis
Snowflake Score
Valuation0/6
Future Growth2/6
Past Performance0/6
Financial Health4/6
Dividends0/6

NMRA Community Fair Values

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See what 11 others think this stock is worth. Follow their fair value or set your own to get alerts.

Neumora Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Neumora Therapeutics
Historical stock prices
Current Share PriceUS$1.72
52 Week HighUS$3.65
52 Week LowUS$0.66
Beta3.05
1 Month Change-21.46%
3 Month Change-50.57%
1 Year Change127.94%
3 Year Changen/a
5 Year Changen/a
Change since IPO-89.42%

Recent News & Updates

New Narrative Apr 15

Multiple Late Stage Brain Disease Programs Will Drive Long Term Upside Potential

Catalysts About Neumora Therapeutics Neumora Therapeutics develops brain penetrant medicines targeting novel mechanisms for psychiatric, neurologic and metabolic diseases. What are the underlying business or industry changes driving this perspective?
New Narrative Apr 01

CNS And Obesity Pipeline Will Create Long Term Value As Late Stage Data Emerges

Catalysts About Neumora Therapeutics Neumora Therapeutics focuses on developing brain penetrant medicines for neuropsychiatric, neurodegenerative, and metabolic diseases. What are the underlying business or industry changes driving this perspective?
Seeking Alpha Mar 30

Neumora Therapeutics: Downgrading After Navacaprant Development Setback

Summary Neumora Therapeutics is downgraded from 'Strong Buy' to 'Hold' following KOASTAL-1's failure in the MDD primary endpoint. KOASTAL-2 and KOASTAL-3 studies for navacaprant in MDD have increased enrollment; topline data is expected in Q2 2026, but success remains uncertain. NMRA-511 showed a promising signal in phase 1b for Alzheimer's Disease agitation, with an enhanced effect in patients with elevated anxiety. Phase 2 study initiation for NMRA-511 in AD agitation is not expected until Q1 2027, making near-term value realization unlikely despite large unmet market need. Read the full article on Seeking Alpha

Recent updates

New Narrative Apr 15

Multiple Late Stage Brain Disease Programs Will Drive Long Term Upside Potential

Catalysts About Neumora Therapeutics Neumora Therapeutics develops brain penetrant medicines targeting novel mechanisms for psychiatric, neurologic and metabolic diseases. What are the underlying business or industry changes driving this perspective?
New Narrative Apr 01

CNS And Obesity Pipeline Will Create Long Term Value As Late Stage Data Emerges

Catalysts About Neumora Therapeutics Neumora Therapeutics focuses on developing brain penetrant medicines for neuropsychiatric, neurodegenerative, and metabolic diseases. What are the underlying business or industry changes driving this perspective?
Seeking Alpha Mar 30

Neumora Therapeutics: Downgrading After Navacaprant Development Setback

Summary Neumora Therapeutics is downgraded from 'Strong Buy' to 'Hold' following KOASTAL-1's failure in the MDD primary endpoint. KOASTAL-2 and KOASTAL-3 studies for navacaprant in MDD have increased enrollment; topline data is expected in Q2 2026, but success remains uncertain. NMRA-511 showed a promising signal in phase 1b for Alzheimer's Disease agitation, with an enhanced effect in patients with elevated anxiety. Phase 2 study initiation for NMRA-511 in AD agitation is not expected until Q1 2027, making near-term value realization unlikely despite large unmet market need. Read the full article on Seeking Alpha
Seeking Alpha Jan 03

Neumora Therapeutics: Tanking On Disastrous MDD Data, Bounce Back Unlikely

Summary Neumora Therapeutics' lead candidate, navacaprant, failed to meet primary and secondary endpoints in its Phase 3 KOASTAL-1 study for major depressive disorder, causing an 80% stock drop yesterday. Despite significant funding and a “promising” Phase 2 study, concerns about endpoint changes and lack of peer-reviewed data undermine confidence in navacaprant's efficacy. With two more Phase 3 studies pending, the market may have overreacted, but the likelihood of a turnaround remains slim given current evidence. Neumora's other assets and cash reserves offer limited near-term revenue prospects, making a contrarian bet on navacaprant risky and ill-advised. Read the full article on Seeking Alpha
Seeking Alpha Dec 24

Neumora: Koastal-1 Readout For MDD Treatment Is First Study On Deck

Summary Neumora Therapeutics is set to release data from the phase 3 KOASTAL-1 study using Navacaprant for the treatment of patients with MDD by the end of 2024; other data in 2025. Navacaprant showed significant efficacy in a phase 2 study for MDD and is also being tested for bipolar depression, with phase 2 data expected in late 2025. Neumora has $341.3 million in cash, enough to fund operations until mid-2026, minimizing near-term dilution risk unless management opts otherwise. Key NMRA risks include the potential failure of KOASTAL-1 to meet primary endpoints and uncertainty in Navacaprant's efficacy for bipolar depression and NMRA-511 for Alzheimer's agitation. Read the full article on Seeking Alpha
Seeking Alpha Oct 16

Neumora Therapeutics: A Story Of A Class II Biotech

Summary Neumora Therapeutics' lead asset, Navacaprant, shows weak efficacy in phase 2 trial, casting doubt on its success in upcoming phase 3 trials. The company's AI-driven precision medicine claims have not materialized in clinical trial designs, undermining their differentiation strategy. Valuation models suggest Neumora's stock is overvalued, with a fair valuation significantly lower than the current market price. Read the full article on Seeking Alpha
Analysis Article Jun 18

We're Hopeful That Neumora Therapeutics (NASDAQ:NMRA) Will Use Its Cash Wisely

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Feb 08

Neumora: Phase 3 MDD Readout In H2-24 Could Get Ball Rolling

Summary Results from the phase 3 KOASTAL-1 study, using Navacaprant for the treatment of patients with Major Depressive Disorder, expected in the 2nd half of 2024. The global Major Depressive Disorder [MDD] treatment market is estimated to reach $14.96 billion by 2032. Company hopes to differentiate itself against other MDD drugs in that Navacaprant has a novel MOA, no side effects seen in approved drugs and treat patients not yet helped. Navacaprant is versatile in that it is believed it could also be used to treat patients with bipolar depression; initiation of phase 2 bipolar depression study using this drug expected in the 1st half of 2024. Read the full article on Seeking Alpha

Shareholder Returns

NMRAUS PharmaceuticalsUS Market
7D-3.4%-0.1%-0.3%
1Y127.9%38.7%26.7%

Return vs Industry: NMRA exceeded the US Pharmaceuticals industry which returned 36.1% over the past year.

Return vs Market: NMRA exceeded the US Market which returned 23.3% over the past year.

Price Volatility

Is NMRA's price volatile compared to industry and market?
NMRA volatility
NMRA Average Weekly Movement11.3%
Pharmaceuticals Industry Average Movement10.0%
Market Average Movement7.2%
10% most volatile stocks in US Market16.2%
10% least volatile stocks in US Market3.2%

Stable Share Price: NMRA's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: NMRA's weekly volatility (11%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
201996n/awww.neumoratx.com

Neumora Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutic treatments for brain diseases, neuropsychiatric disorders, and neurodegenerative diseases in the United States. The company develops navacaprant (NMRA-140), a novel once-daily oral kappa opioid receptor antagonist, which is in phase 3 clinical trials for the treatment of major depressive disorder. It also develops NMRA-511 that is in Phase 1b clinical trials in patients with agitation associated with dementia due to Alzheimer’s disease; and NMRA-861 and NMRA-898, a M4 muscarinic receptor positive allosteric modulators (PAMs) for schizophrenia and other neuropsychiatric disorders.

Neumora Therapeutics, Inc. Fundamentals Summary

How do Neumora Therapeutics's earnings and revenue compare to its market cap?
NMRA fundamental statistics
Market capUS$305.09m
Earnings (TTM)-US$222.39m
Revenue (TTM)n/a
0.0x
P/S Ratio
-1.4x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
NMRA income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$222.39m
Earnings-US$222.39m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-1.22
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio52.5%

How did NMRA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/20 13:46
End of Day Share Price 2026/05/20 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Neumora Therapeutics, Inc. is covered by 10 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Yatin SunejaGuggenheim Securities, LLC
Douglas TsaoH.C. Wainwright & Co.
Tessa RomeroJ.P. Morgan