How Investors May Respond To Mirum Pharmaceuticals (MIRM) Profitability, Raised Guidance, and Positive Liver Disease Data

• Mirum Pharmaceuticals recently reported strong third-quarter financial results, including a swing to profitability and substantial year-over-year revenue growth, alongside raising its full-year 2025 revenue guidance to the upper end of its prior range.
• The company also announced new and positive clinical data for its key therapies, LIVMARLI and volixibat, to be featured at the American Association for the Study of Liver Diseases’ (AASLD) 2025 Liver Meeting, underscoring advances in addressing rare liver diseases.
• We'll explore how Mirum's raised revenue guidance and positive clinical updates strengthen its investment narrative focused on rare disease therapies.

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Mirum Pharmaceuticals Investment Narrative Recap

To own Mirum Pharmaceuticals stock, you need to believe in the company’s ability to lead and expand in rare liver disease therapies, maintaining momentum in commercial growth while mitigating reliance on LIVMARLI. The uptick in revenue guidance and encouraging clinical updates strengthen near-term confidence in pipeline diversification, but do not eliminate the central risk stemming from concentration in one key therapy and sensitivity to reimbursement trends. The latest financial report stands out, with Mirum swinging to profitability in the third quarter as revenue reached US$133.01 million, reflecting operational progress amidst pipeline execution. In contrast, investors should remain alert to the risk that new therapies or reimbursement changes could rapidly shift Mirum’s growth trajectory…

Read the full narrative on Mirum Pharmaceuticals (it's free!)

Mirum Pharmaceuticals' outlook anticipates $794.3 million in revenue and $102.1 million in earnings by 2028. Achieving this will require annual revenue growth of 22.8% and an earnings increase of $160.7 million from the current earnings of -$58.6 million.

Uncover how Mirum Pharmaceuticals' forecasts yield a $86.09 fair value, a 21% upside to its current price.

Exploring Other Perspectives

Private investors in the Simply Wall St Community valued Mirum between US$34.86 and US$186.18, based on four separate fair value estimates. As optimism builds on recent guidance, opinions remain split on how expansion beyond LIVMARLI might affect future performance.

Explore 4 other fair value estimates on Mirum Pharmaceuticals - why the stock might be worth over 2x more than the current price!

Build Your Own Mirum Pharmaceuticals Narrative

Disagree with existing narratives? Create your own in under 3 minutes - extraordinary investment returns rarely come from following the herd.

• A great starting point for your Mirum Pharmaceuticals research is our analysis highlighting 4 key rewards that could impact your investment decision.
• Our free Mirum Pharmaceuticals research report provides a comprehensive fundamental analysis summarized in a single visual - the Snowflake - making it easy to evaluate Mirum Pharmaceuticals' overall financial health at a glance.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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