MacroGenics, Inc.

NasdaqGS:MGNX Stock Report

Market Cap: US$187.5m

MacroGenics Past Earnings Performance

Past criteria checks 0/6

MacroGenics has been growing earnings at an average annual rate of 25%, while the Biotechs industry saw earnings growing at 30.5% annually. Revenues have been growing at an average rate of 7.2% per year.

Key information

24.99%

Earnings growth rate

27.41%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate7.17%
Return on equity-134.23%
Net Margin-49.91%
Last Earnings Update31 Dec 2025

Recent past performance updates

Recent updates

Narrative Update Apr 26

MGNX: Antibody Drug Conjugate Pipeline And 2026 Data Will Drive Repricing

Narrative Update on MacroGenics Analysts have raised their price targets on MacroGenics by $2 to $4. They cite updated revenue assumptions and interest in the company’s antibody drug conjugate pipeline as key factors behind the change.
Narrative Update Apr 12

MGNX: Antibody Drug Conjugate Pipeline And Tubulus Deal Will Drive Repricing

Analysts raised their price target for MacroGenics from $5.00 to $9.00, citing updated assumptions for potential revenue growth, slightly higher profit margins, a lower discount rate and recent positive sentiment following the Tubulus deal and the outlook for antibody-drug conjugate data. Analyst Commentary Bullish analysts are pointing to recent research updates as a sign that expectations for MacroGenics are shifting toward a more constructive view, with price targets and ratings adjusted to reflect changing assumptions around future execution and potential revenue streams.
Seeking Alpha Apr 10

MacroGenics: Oncology Opportunities In Play, But Investing Feels Like A Gamble

Summary MacroGenics (MGNX) is rated Hold, reflecting significant upside potential but high risk and a limited funding runway beyond 2027. MGNX’s pipeline includes antibody drug conjugates and lorigerlimab, with the latter’s Phase 2 clinical hold recently lifted by the FDA. Key 2026 catalysts include clinical data from MGC026, MGC028, and the LINNET study, plus an IND submission for MGC030. Despite past setbacks and a $190m cash position, MGNX’s current valuation implies little pipeline value, making study success critical for future funding. Read the full article on Seeking Alpha
Analysis Article Jan 06

There's No Escaping MacroGenics, Inc.'s (NASDAQ:MGNX) Muted Revenues Despite A 26% Share Price Rise

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders are no doubt pleased to see that the share price has bounced 26% in the...
Narrative Update Sep 25

LORIKEET And LINNET Trials Will Spur Advances Amid Liquidity Risks

The consensus analyst price target for MacroGenics increased to $3.75, primarily reflecting a higher expected future P/E multiple despite a decline in net profit margin. What's in the News Eric Risser appointed Chief Executive Officer, succeeding long-time CEO Scott Koenig; Risser has extensive company and industry experience, having led corporate development efforts that generated $1.6 billion in non-dilutive capital.
Analysis Article Sep 08

MacroGenics, Inc.'s (NASDAQ:MGNX) Share Price Boosted 30% But Its Business Prospects Need A Lift Too

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders would be excited to see that the share price has had a great month...
Narrative Update Aug 16

LORIKEET And LINNET Trials Will Spur Advances Amid Liquidity Risks

Despite an improving net profit margin and a sharply lower future P/E multiple reflecting more attractive valuation, the consensus analyst price target for MacroGenics has been notably reduced from $4.20 to $3.40. What's in the News Eric Risser appointed CEO, succeeding longtime leader Scott Koenig; Risser brings significant operational and business development experience, including generating over $1.6 billion in non-dilutive capital for the company.
Analysis Article Jul 24

MacroGenics, Inc. (NASDAQ:MGNX) Surges 37% Yet Its Low P/S Is No Reason For Excitement

MacroGenics, Inc. ( NASDAQ:MGNX ) shares have had a really impressive month, gaining 37% after a shaky period...
Analysis Article May 21

Analyst Forecasts For MacroGenics, Inc. (NASDAQ:MGNX) Are Surging Higher

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders will have a reason to smile today, with the analysts making substantial...
Analysis Article Apr 14

MacroGenics, Inc. (NASDAQ:MGNX) Looks Inexpensive After Falling 42% But Perhaps Not Attractive Enough

Unfortunately for some shareholders, the MacroGenics, Inc. ( NASDAQ:MGNX ) share price has dived 42% in the last thirty...
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New Narrative Apr 02

LORIKEET And LINNET Trials Will Spur Advances Amid Liquidity Risks

Future revenue growth potential hinges on successful trial outcomes and product approvals in ongoing and upcoming clinical studies.
Analysis Article Feb 28

MacroGenics, Inc. (NASDAQ:MGNX) Not Doing Enough For Some Investors As Its Shares Slump 26%

Unfortunately for some shareholders, the MacroGenics, Inc. ( NASDAQ:MGNX ) share price has dived 26% in the last thirty...
Seeking Alpha Feb 27

MacroGenics: Stacking Up A Lot Of Headwinds... But It's Fallen Too Far

Summary MacroGenics' valuation has declined due to continued bad news in 2024, impacting market sentiment. MGNX holds $179.6M in cash and equivalents, with a sustainable cash burn rate for up to 5 years. Sale of the margetuximab franchise poises the company for further financial stability. Operating expenses are expected to rise as clinical programs advance, with management projecting a cash runway into 2026. I think this is a conservative estimate. Although a lot has changed, I think these price levels are attractive for a tentative investment based on catalysts I anticipate in 2025 and beyond. Read the full article on Seeking Alpha
Seeking Alpha Dec 05

MacroGenics: A Productive Biotech With Growing Potential - Still Not A Buy

Summary MacroGenix was previously rated as a "Hold" due to uncertain revenue streams and high annual expenses of ~$300 million. Since the initial rating, MacroGenix's stock has dropped approximately 33%, reflecting ongoing financial challenges. The company's reliance on episodic milestones and minimal product revenues makes it unattractive for new investors. Existing investors might accept the risk, but the current financial outlook remains unattractive for prospective buyers. Read the full article on Seeking Alpha
Analysis Article Aug 01

Party Time: Brokers Just Made Major Increases To Their MacroGenics, Inc. (NASDAQ:MGNX) Earnings Forecasts

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders will have a reason to smile today, with the analysts making substantial...
Analysis Article Jul 30

MacroGenics, Inc.'s (NASDAQ:MGNX) Share Price Boosted 29% But Its Business Prospects Need A Lift Too

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders are no doubt pleased to see that the share price has bounced 29% in the...
Analysis Article Jul 12

We're A Little Worried About MacroGenics' (NASDAQ:MGNX) Cash Burn Rate

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Analysis Article May 13

MacroGenics, Inc.'s (NASDAQ:MGNX) 81% Dip In Price Shows Sentiment Is Matching Revenues

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders that were waiting for something to happen have been dealt a blow with a...
Seeking Alpha May 13

MacroGenics: Strong Likelihood Bad News Has Caused Overreaction (Rating Upgrade)

Summary Macrogenics' stock valuation has dropped over 70% after its first quarter update, creating a new opportunity for investors. The spotlight is on their product vobramitamab duocarmazine, and the phase 2 TAMARACK trial. Macrogenics has between 4 and 5 quarters of cash and investments on hand. Read the full article on Seeking Alpha
Seeking Alpha Apr 05

MacroGenics: Positive Safety Update Leads To Two Major Inflection Points In 2024

Summary Positive safety update released from phase 2 TAMARACK study, using vobra duo for the treatment of patients with metastatic castration-resistant prostate cancer. Updates to interim data from the phase 2 TAMARACK study expected by May 31st of 2024. Radiographic progression-free survival data from the phase 2 TAMARACK study, expected by fall of 2024. The global prostate cancer market size is estimated to reach $27.51 billion by 2032. Read the full article on Seeking Alpha
Analysis Article Feb 28

MacroGenics, Inc. (NASDAQ:MGNX) Surges 27% Yet Its Low P/S Is No Reason For Excitement

Despite an already strong run, MacroGenics, Inc. ( NASDAQ:MGNX ) shares have been powering on, with a gain of 27% in...
Seeking Alpha Feb 15

MacroGenics: Trying To Build A Better Everything

Summary MacroGenics, Inc. has a pipeline of promising drugs including Vobramitamab Duocarmazine, Lorigerlimab, Tebotelimab, MGD024, and IMGC936. The company has a strong financial position as of their latest report. MacroGenics faces both strengths and risks in their drug development and commercialization efforts. Read the full article on Seeking Alpha
Analysis Article Jan 09

There's No Escaping MacroGenics, Inc.'s (NASDAQ:MGNX) Muted Revenues

With a price-to-sales (or "P/S") ratio of 5.4x MacroGenics, Inc. ( NASDAQ:MGNX ) may be sending very bullish signals at...

Revenue & Expenses Breakdown

How MacroGenics makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:MGNX Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Dec 25150-75390
30 Sep 25128-76580
30 Jun 25165-36620
31 Mar 25154-56670
31 Dec 24150-67710
30 Sep 24141-98560
30 Jun 2441-13654-84
31 Mar 2443-23530
31 Dec 2359-9520
30 Sep 2312150530
30 Jun 2315275684
31 Mar 23165-91560
31 Dec 22152-120590
30 Sep 2293-191610
30 Jun 2267-219630
31 Mar 2272-217640
31 Dec 2177-202630
30 Sep 21116-146600
30 Jun 21119-129530
31 Mar 21108-136480
31 Dec 20105-130430
30 Sep 2077-158420
30 Jun 2078-167440
31 Mar 2068-152460
31 Dec 1964-152460
30 Sep 1955-166450
30 Jun 1957-155420
31 Mar 1965-167410
31 Dec 1860-171410
30 Sep 18197-21380
30 Jun 18178-34370
31 Mar 18160-32340
31 Dec 17158-20330
30 Sep 1710-160330
30 Jun 1712-147320
31 Mar 1791-66310
31 Dec 1692-59300
30 Sep 1695-52270
30 Jun 16106-34260
31 Mar 1632-96240
31 Dec 15101-20230
30 Sep 1598-11210
30 Jun 151021190

Quality Earnings: MGNX is currently unprofitable.

Growing Profit Margin: MGNX is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: MGNX is unprofitable, but has reduced losses over the past 5 years at a rate of 25% per year.

Accelerating Growth: Unable to compare MGNX's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: MGNX is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (43%).


Return on Equity

High ROE: MGNX has a negative Return on Equity (-134.23%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/12 22:33
End of Day Share Price 2026/05/12 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

MacroGenics, Inc. is covered by 17 analysts. 6 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Etzer DaroutBarclays
Peter LawsonBarclays
Stephen V. ByrneBofA Global Research