MacroGenics, Inc.

NasdaqGS:MGNX Stock Report

Market Cap: US$200.2m

MacroGenics Management

Management criteria checks 2/4

MacroGenics' CEO is Eric Risser, appointed in Aug 2025, has a tenure of less than a year. total yearly compensation is $2.08M, comprised of 27% salary and 73% bonuses, including company stock and options. directly owns 0.12% of the company’s shares, worth $243.08K. The average tenure of the management team and the board of directors is 2.5 years and 8.5 years respectively.

Key information

Eric Risser

Chief executive officer

US$2.1m

Total compensation

CEO salary percentage27.01%
CEO tenureless than a year
CEO ownership0.1%
Management average tenure2.5yrs
Board average tenure8.5yrs

Recent management updates

Recent updates

Narrative Update Apr 26

MGNX: Antibody Drug Conjugate Pipeline And 2026 Data Will Drive Repricing

Narrative Update on MacroGenics Analysts have raised their price targets on MacroGenics by $2 to $4. They cite updated revenue assumptions and interest in the company’s antibody drug conjugate pipeline as key factors behind the change.
Narrative Update Apr 12

MGNX: Antibody Drug Conjugate Pipeline And Tubulus Deal Will Drive Repricing

Analysts raised their price target for MacroGenics from $5.00 to $9.00, citing updated assumptions for potential revenue growth, slightly higher profit margins, a lower discount rate and recent positive sentiment following the Tubulus deal and the outlook for antibody-drug conjugate data. Analyst Commentary Bullish analysts are pointing to recent research updates as a sign that expectations for MacroGenics are shifting toward a more constructive view, with price targets and ratings adjusted to reflect changing assumptions around future execution and potential revenue streams.
Seeking Alpha Apr 10

MacroGenics: Oncology Opportunities In Play, But Investing Feels Like A Gamble

Summary MacroGenics (MGNX) is rated Hold, reflecting significant upside potential but high risk and a limited funding runway beyond 2027. MGNX’s pipeline includes antibody drug conjugates and lorigerlimab, with the latter’s Phase 2 clinical hold recently lifted by the FDA. Key 2026 catalysts include clinical data from MGC026, MGC028, and the LINNET study, plus an IND submission for MGC030. Despite past setbacks and a $190m cash position, MGNX’s current valuation implies little pipeline value, making study success critical for future funding. Read the full article on Seeking Alpha
Analysis Article Jan 06

There's No Escaping MacroGenics, Inc.'s (NASDAQ:MGNX) Muted Revenues Despite A 26% Share Price Rise

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders are no doubt pleased to see that the share price has bounced 26% in the...
Narrative Update Sep 25

LORIKEET And LINNET Trials Will Spur Advances Amid Liquidity Risks

The consensus analyst price target for MacroGenics increased to $3.75, primarily reflecting a higher expected future P/E multiple despite a decline in net profit margin. What's in the News Eric Risser appointed Chief Executive Officer, succeeding long-time CEO Scott Koenig; Risser has extensive company and industry experience, having led corporate development efforts that generated $1.6 billion in non-dilutive capital.
Analysis Article Sep 08

MacroGenics, Inc.'s (NASDAQ:MGNX) Share Price Boosted 30% But Its Business Prospects Need A Lift Too

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders would be excited to see that the share price has had a great month...
Narrative Update Aug 16

LORIKEET And LINNET Trials Will Spur Advances Amid Liquidity Risks

Despite an improving net profit margin and a sharply lower future P/E multiple reflecting more attractive valuation, the consensus analyst price target for MacroGenics has been notably reduced from $4.20 to $3.40. What's in the News Eric Risser appointed CEO, succeeding longtime leader Scott Koenig; Risser brings significant operational and business development experience, including generating over $1.6 billion in non-dilutive capital for the company.
Analysis Article Jul 24

MacroGenics, Inc. (NASDAQ:MGNX) Surges 37% Yet Its Low P/S Is No Reason For Excitement

MacroGenics, Inc. ( NASDAQ:MGNX ) shares have had a really impressive month, gaining 37% after a shaky period...
Analysis Article May 21

Analyst Forecasts For MacroGenics, Inc. (NASDAQ:MGNX) Are Surging Higher

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders will have a reason to smile today, with the analysts making substantial...
Analysis Article Apr 14

MacroGenics, Inc. (NASDAQ:MGNX) Looks Inexpensive After Falling 42% But Perhaps Not Attractive Enough

Unfortunately for some shareholders, the MacroGenics, Inc. ( NASDAQ:MGNX ) share price has dived 42% in the last thirty...
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New Narrative Apr 02

LORIKEET And LINNET Trials Will Spur Advances Amid Liquidity Risks

Future revenue growth potential hinges on successful trial outcomes and product approvals in ongoing and upcoming clinical studies.
Analysis Article Feb 28

MacroGenics, Inc. (NASDAQ:MGNX) Not Doing Enough For Some Investors As Its Shares Slump 26%

Unfortunately for some shareholders, the MacroGenics, Inc. ( NASDAQ:MGNX ) share price has dived 26% in the last thirty...
Seeking Alpha Feb 27

MacroGenics: Stacking Up A Lot Of Headwinds... But It's Fallen Too Far

Summary MacroGenics' valuation has declined due to continued bad news in 2024, impacting market sentiment. MGNX holds $179.6M in cash and equivalents, with a sustainable cash burn rate for up to 5 years. Sale of the margetuximab franchise poises the company for further financial stability. Operating expenses are expected to rise as clinical programs advance, with management projecting a cash runway into 2026. I think this is a conservative estimate. Although a lot has changed, I think these price levels are attractive for a tentative investment based on catalysts I anticipate in 2025 and beyond. Read the full article on Seeking Alpha
Seeking Alpha Dec 05

MacroGenics: A Productive Biotech With Growing Potential - Still Not A Buy

Summary MacroGenix was previously rated as a "Hold" due to uncertain revenue streams and high annual expenses of ~$300 million. Since the initial rating, MacroGenix's stock has dropped approximately 33%, reflecting ongoing financial challenges. The company's reliance on episodic milestones and minimal product revenues makes it unattractive for new investors. Existing investors might accept the risk, but the current financial outlook remains unattractive for prospective buyers. Read the full article on Seeking Alpha
Analysis Article Aug 01

Party Time: Brokers Just Made Major Increases To Their MacroGenics, Inc. (NASDAQ:MGNX) Earnings Forecasts

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders will have a reason to smile today, with the analysts making substantial...
Analysis Article Jul 30

MacroGenics, Inc.'s (NASDAQ:MGNX) Share Price Boosted 29% But Its Business Prospects Need A Lift Too

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders are no doubt pleased to see that the share price has bounced 29% in the...
Analysis Article Jul 12

We're A Little Worried About MacroGenics' (NASDAQ:MGNX) Cash Burn Rate

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Analysis Article May 13

MacroGenics, Inc.'s (NASDAQ:MGNX) 81% Dip In Price Shows Sentiment Is Matching Revenues

MacroGenics, Inc. ( NASDAQ:MGNX ) shareholders that were waiting for something to happen have been dealt a blow with a...
Seeking Alpha May 13

MacroGenics: Strong Likelihood Bad News Has Caused Overreaction (Rating Upgrade)

Summary Macrogenics' stock valuation has dropped over 70% after its first quarter update, creating a new opportunity for investors. The spotlight is on their product vobramitamab duocarmazine, and the phase 2 TAMARACK trial. Macrogenics has between 4 and 5 quarters of cash and investments on hand. Read the full article on Seeking Alpha
Seeking Alpha Apr 05

MacroGenics: Positive Safety Update Leads To Two Major Inflection Points In 2024

Summary Positive safety update released from phase 2 TAMARACK study, using vobra duo for the treatment of patients with metastatic castration-resistant prostate cancer. Updates to interim data from the phase 2 TAMARACK study expected by May 31st of 2024. Radiographic progression-free survival data from the phase 2 TAMARACK study, expected by fall of 2024. The global prostate cancer market size is estimated to reach $27.51 billion by 2032. Read the full article on Seeking Alpha
Analysis Article Feb 28

MacroGenics, Inc. (NASDAQ:MGNX) Surges 27% Yet Its Low P/S Is No Reason For Excitement

Despite an already strong run, MacroGenics, Inc. ( NASDAQ:MGNX ) shares have been powering on, with a gain of 27% in...
Seeking Alpha Feb 15

MacroGenics: Trying To Build A Better Everything

Summary MacroGenics, Inc. has a pipeline of promising drugs including Vobramitamab Duocarmazine, Lorigerlimab, Tebotelimab, MGD024, and IMGC936. The company has a strong financial position as of their latest report. MacroGenics faces both strengths and risks in their drug development and commercialization efforts. Read the full article on Seeking Alpha
Analysis Article Jan 09

There's No Escaping MacroGenics, Inc.'s (NASDAQ:MGNX) Muted Revenues

With a price-to-sales (or "P/S") ratio of 5.4x MacroGenics, Inc. ( NASDAQ:MGNX ) may be sending very bullish signals at...

CEO Compensation Analysis

How has Eric Risser's remuneration changed compared to MacroGenics's earnings?
DateTotal CompensationSalaryCompany Earnings
Dec 31 2025US$2mUS$562k

-US$75m

Sep 30 2025n/an/a

-US$76m

Jun 30 2025n/an/a

-US$36m

Mar 31 2025n/an/a

-US$56m

Dec 31 2024n/an/a

-US$67m

Sep 30 2024n/an/a

-US$98m

Jun 30 2024n/an/a

-US$136m

Mar 31 2024n/an/a

-US$23m

Dec 31 2023n/an/a

-US$9m

Sep 30 2023n/an/a

US$50m

Jun 30 2023n/an/a

US$7m

Mar 31 2023n/an/a

-US$91m

Dec 31 2022US$2mUS$461k

-US$120m

Sep 30 2022n/an/a

-US$191m

Jun 30 2022n/an/a

-US$219m

Mar 31 2022n/an/a

-US$217m

Dec 31 2021US$2mUS$428k

-US$202m

Sep 30 2021n/an/a

-US$146m

Jun 30 2021n/an/a

-US$129m

Mar 31 2021n/an/a

-US$136m

Dec 31 2020US$1mUS$431k

-US$130m

Sep 30 2020n/an/a

-US$158m

Jun 30 2020n/an/a

-US$167m

Mar 31 2020n/an/a

-US$152m

Dec 31 2019US$2mUS$388k

-US$152m

Compensation vs Market: Eric's total compensation ($USD2.08M) is above average for companies of similar size in the US market ($USD1.59M).

Compensation vs Earnings: Eric's compensation has increased whilst the company is unprofitable.


CEO

Eric Risser (52 yo)

less than a year
Tenure
US$2,078,854
Compensation

Mr. Eric Blasius Risser is President, Chief Executive Officer and Director at MacroGenics, Inc. since August 13, 2025. He served as Chief Operating Officer at MacroGenics, Inc. since February 22, 2022 unti...


Leadership Team

NamePositionTenureCompensationOwnership
Eric Risser
CEO, President & Directorless than a yearUS$2.08m0.12%
$ 243.1k
James Karrels
Senior VP18yrsUS$1.15m0.32%
$ 649.0k
Ezio Bonvini
Senior VP of Research & Chief Scientific Officer9.7yrsUS$1.22m0.23%
$ 459.3k
Thomas Spitznagel
Senior Vice President of Technical Operations3.5yrsUS$1.88m0.061%
$ 121.4k
Jeffrey Peters
Senior VP8.9yrsno data0.049%
$ 98.0k
Steve Harig
Senior Vice President of Human Resourcesno datano datano data
Harish Krishnaswamy
Senior Vice President of Business Development & Portfolio Planningless than a yearno datano data
Frank Perabo
Vice President & Interim Head of Clinical Developmentless than a yearno datano data
Beth Smith
VP, Controller & Treasurer1.5yrsno data0.020%
$ 40.3k
2.5yrs
Average Tenure
58yo
Average Age

Experienced Management: MGNX's management team is considered experienced (2.5 years average tenure).


Board Members

NamePositionTenureCompensationOwnership
Eric Risser
CEO, President & Directorless than a yearUS$2.08m0.12%
$ 243.1k
David Stump
Independent Director12.7yrsUS$95.86k0.017%
$ 34.7k
Federica O'Brien
Independent Director5.3yrsUS$110.48k0.017%
$ 34.7k
Edward Hurwitz
Independent Director21.6yrsUS$85.86k0.069%
$ 138.8k
Margaret Liu
Independent Director3.3yrsUS$85.86k0.017%
$ 34.7k
Scott Koenig
Director24.7yrsUS$969.84k1.36%
$ 2.7m
William Heiden
Independent Chairman of the Board4yrsUS$145.03k0.17%
$ 349.7k
Meenu Chhabra Karson
Independent Director3.3yrsUS$80.22k0.017%
$ 34.7k
Scott Jackson
Independent Director9.3yrsUS$81.91k0.017%
$ 34.7k
Jay Siegel
Independent Director8.5yrsUS$106.28k0.017%
$ 34.7k
Karen Jean Ferrante
Independent Director9.3yrsUS$85.86k0.017%
$ 34.7k
8.5yrs
Average Tenure
67yo
Average Age

Experienced Board: MGNX's board of directors are considered experienced (8.5 years average tenure).


Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/06 05:35
End of Day Share Price 2026/05/06 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

MacroGenics, Inc. is covered by 17 analysts. 5 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Etzer DaroutBarclays
Peter LawsonBarclays
Stephen V. ByrneBofA Global Research