Kazia Therapeutics (KZIA) Stock Overview

Operates as an oncology-focused biotechnology company in Israel. More details

KZIA fundamental analysis
Snowflake Score
Valuation	0/6
Future Growth	2/6
Past Performance	0/6
Financial Health	5/6
Dividends	0/6

Rewards

Revenue is forecast to grow 87.97% per year

Risk Analysis

Shareholders have been substantially diluted in the past year

Volatile share price over the past 3 months compared to the US market

Does not have meaningful revenue (A$2M)

Currently unprofitable and not forecast to become profitable over the next 3 years

KZIA Community Fair Values

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Kazia Therapeutics Limited Competitors

Price History & Performance

Summary of share price highs, lows and changes for Kazia Therapeutics
Historical stock prices
Current Share Price	US$11.42
52 Week High	US$17.40
52 Week Low	US$4.86
Beta	2.18
1 Month Change	-20.91%
3 Month Change	40.81%
1 Year Change	117.30%
3 Year Change	-82.56%
5 Year Change	-97.87%
Change since IPO	-99.86%

Recent updates

Seeking Alpha • Jul 06

Kazia gains on FDA’s rare pediatric disease designation for childhood cancer therapy

The ADRs of Australian biotech Kazia Therapeutics (NASDAQ:KZIA) gained 8% Wednesday after the company announced that the U.S. Food and Drug Administration (FDA) granted the Rare Pediatric Disease Designation for an experimental therapy targeted at a form of childhood cancer. Paxalisib a brain-penetrant inhibitor received the designation as a treatment for atypical rhabdoid / teratoid tumors (AT/RT), a rare and highly aggressive childhood brain cancer, Kazia (KZIA) said in a press release. In awarding the RPD tag, the federal agency picks drug candidates targeted at serious and life-threatening diseases affecting less than 200K individuals in the U.S. with a primary impact on children aged 18 years or younger. If a drug with a rare pediatric disease designation wins FDA approval, the sponsor of its marketing application is entitled to receive a Priority Review Voucher (PRV) from the regulator. The PRVs valued at more than $100M historically, can be redeemed to receive a priority review for any subsequent marketing application, or it can be sold. In June, Kazia (KZIA) announced that the FDA awarded orphan drug designation for Paxalisib for the same condition.

Shareholder Returns

	KZIA	US Biotechs	US Market
7D	-3.1%	-1.7%	-2.7%
1Y	117.3%	24.3%	22.5%

Return vs Industry: KZIA exceeded the US Biotechs industry which returned 24.3% over the past year.

Return vs Market: KZIA exceeded the US Market which returned 22.5% over the past year.

Price Volatility

Is KZIA's price volatile compared to industry and market?
KZIA volatility
KZIA Average Weekly Movement	13.5%
Biotechs Industry Average Movement	10.8%
Market Average Movement	7.2%
10% most volatile stocks in US Market	16.6%
10% least volatile stocks in US Market	3.1%

Stable Share Price: KZIA's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: KZIA's weekly volatility has decreased from 22% to 13% over the past year, but is still higher than 75% of US stocks.

About the Company

Founded	Employees	CEO	Website
1994	6	John Friend	www.kaziatherapeutics.com

Kazia Therapeutics Limited, together with its subsidiaries, operates as an oncology-focused biotechnology company in Israel. The company's lead development candidate is paxalisib, a small molecule, brain-penetrant inhibitor of the phosphoinositide-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, which is in Phase II/III clinical trial for the treatment of glioblastoma; in Phase II trial to treat isocitrate dehydrogenase-mutant glioma, primary central nervous system (CNS) lymphoma, diffuse intrinsic pontine glioma, and brain metastases; and in pre-clinical studies to treat triple-negative breast cancer, as well as for the treatment of atypical rhabdoid/teratoid tumors. It also develops EVT801, a small-molecule selective inhibitor of vascular endothelial growth factor receptor 3 that is in Phase I clinical trial to treat advanced solid tumors and ovarian cancer.

Kazia Therapeutics Limited Fundamentals Summary

How do Kazia Therapeutics's earnings and revenue compare to its market cap?
KZIA fundamental statistics
Market cap	US$130.27m
Earnings (TTM)	-US$16.06m
Revenue (TTM)	US$1.34m

97.6x

P/S Ratio

-8.1x

P/E Ratio

Is KZIA overvalued?

See Fair Value and valuation analysis

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
KZIA income statement (TTM)
Revenue	AU$1.90m
Cost of Revenue	AU$0
Gross Profit	AU$1.90m
Other Expenses	AU$24.70m
Earnings	-AU$22.80m

Last Reported Earnings

Dec 31, 2025

Next Earnings Date

n/a

Earnings per share (EPS)	-2.00
Gross Margin	100.00%
Net Profit Margin	-1,200.90%
Debt/Equity Ratio	0.2%

How did KZIA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

Data	Last Updated (UTC time)
Company Analysis	2026/06/09 22:27
End of Day Share Price	2026/06/09 00:00
Earnings	2025/12/31
Annual Earnings	2025/06/30

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

Package	Data	Timeframe	Example US Source ^*
Company Financials	10 years	Income statement Cash flow statement Balance sheet	SEC Form 10-K SEC Form 10-Q
Analyst Consensus Estimates	+3 years	Forecast financials Analyst price targets	Analyst Research Reports Blue Matrix
Market Prices	30 years	Stock prices Dividends, Splits and Actions	ICE Market Data SEC Form S-1
Ownership	10 years	Top shareholders Insider trading	SEC Form 4 SEC Form 13D
Management	10 years	Leadership team Board of directors	SEC Form 10-K SEC Form DEF 14A
Key Developments	10 years	Company announcements	SEC Form 8-K

^* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Kazia Therapeutics Limited is covered by 4 analysts. 3 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

Analyst	Institution
Soo Romanoff	Edison Investment Research
Sean Lee	H.C. Wainwright & Co.
I-Eh Jen	Laidlaw & Company (UK) Ltd

Kazia Therapeutics (KZIA) Stock Overview

Rewards

Risk Analysis

Kazia Therapeutics Limited Competitors

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Price History & Performance

Recent News & Updates

New major risk - Revenue and earnings growth

Kazia Therapeutics Limited Announces Appointment of James Levine to Chief Financial Officer, Effective June 1, 2026

Consensus EPS estimates upgraded to AU$0.016 loss

Kazia Therapeutics Expands Ongoing Phase 1B Trial of Paxalisib in Advanced Breast Cancer

Kazia Therapeutics Limited Appoints Dr. Sudha Rao as Chief Scientific Officer

Kazia Therapeutics Limited Expands Oncology Platform with First-In-Class SETDB1 Inhibitor Drug Development Platform

Recent updates

New major risk - Revenue and earnings growth

Kazia Therapeutics Limited Announces Appointment of James Levine to Chief Financial Officer, Effective June 1, 2026

Consensus EPS estimates upgraded to AU$0.016 loss

Kazia Therapeutics Expands Ongoing Phase 1B Trial of Paxalisib in Advanced Breast Cancer

Kazia Therapeutics Limited Appoints Dr. Sudha Rao as Chief Scientific Officer

Kazia Therapeutics Limited Expands Oncology Platform with First-In-Class SETDB1 Inhibitor Drug Development Platform

First half 2026 earnings released: AU$4.02 loss per share (vs AU$12.29 loss in 1H 2025)

New major risk - Negative shareholders equity

Kazia Therapeutics Limited has filed a Follow-on Equity Offering in the amount of $100 million.

Kazia Therapeutics Announces Compelling Preclinical and Translational Data for Nuclear PD-L1 Degrader (NDL2)

Kazia Therapeutics Reports Encouraging Preliminary Clinical Responses in Ongoing Phase 1B Study of Paxalisib in Late-Stage Metastatic Triple-Negative Breast Cancer

Kazia Therapeutics Highlights New Clinical and Translational Findings Demonstrating Paxalisib's Ability to Reinvigorate Anti-Tumor Immunity Across Multiple Advanced Breast Cancer Populations Including TNBC and HER2+

Kazia Therapeutics Limited announced that it expects to receive $50.000896 million in funding from ADAR1 Capital Management, LLC, Ikarian Capital, LLC, Stonepine Capital Management LLC, Velan Capital Partners LP, Revach Capital Management LLC

Kazia Therapeutics Limited Achieves Initial iCR (Immune- Complete Response) in Metastatic TNBC and Delivers Fourth Quarter Business Update with Breakthroughs Across Breast Cancer, Immuno-Oncology, and GBM Regulatory Strategy

Kazia Therapeutics Limited announced delayed 20-F filing

Kazia Therapeutics Limited Plans to Request Type C Meeting with U.S. Food & Drug Administration to Discuss Overall Survival Data in GBM and Potential NDA Filing in Alignment with FDA Initiative Project FrontRunner

Kazia Therapeutics Announces 86% Reduction in Tumor Burden in Expanded-Access Case of Metastatic Tnbc Patient Treatment with Paxalisib-Immunotherapy Regimen

Kazia Therapeutics Reports Complete Ex Vivo Disruption of Large Circulating Tumor Cell Clusters in Stage Iv Her2-Positive Breast Cancer with Paxalisib Monotherapy

Kazia Therapeutics Limited announced that it expects to receive $2.049992 million in funding

Kazia Therapeutics Limited has filed a Follow-on Equity Offering in the amount of $1.906196 million.

Kazia Therapeutics Reports Early Efficacy Data from First Triple-Negative Breast Cancer Patient Receiving Paxalisib Combination Regimen Achieves >50% Reduction in Circulating Tumor Cells in Phase 1B Trial

First half 2025 earnings released: AU$12.29 loss per share (vs AU$18.40 loss in 1H 2024)

Kazia Therapeutics Announces Transformative Preclinical Data Demonstrating Paxalisib's Potential to Overcome Immunotherapy Resistance in Triple-Negative Breast Cancer

Kazia Therapeutics Limited Announces First Patient Dosed in Phase 1b Trial of Paxalisib in Advanced Breast Cancer

New minor risk - Financial data availability

High number of new and inexperienced directors

Kazia Therapeutics Limited Announces the Launch of A Groundbreaking Trial with Paxalisib in Combination with Immunotherapy in Women with Advanced Breast Cancer

Kazia Therapeutics Limited has completed a Follow-on Equity Offering in the amount of $1.999922 million.

Kazia Therapeutics Limited has filed a Follow-on Equity Offering in the amount of $2 million.

Kazia Therapeutics Limited Provides Update on Paxalisib Regulatory Pathway Following Type C Meeting with FDA

Kazia Therapeutics Limited Announces to Present Data Highlighting Synergistic Activity Between Paxalisib and Immunotherapy in Immunotherapy-Resistant Triple Negative Breast Cancer Model at the San Antonio Breast Cancer Symposium

Kazia Therapeutics Limited Announces Granting of Type C Meeting with FDA to Discuss Potential Next Steps for Paxalisib in the Treatment of Newly Diagnosed Glioblastoma Multiforme

Kazia Therapeutics Limited announced delayed 20-F filing

New minor risk - Financial data availability

Kazia Therapeutics Announces Presentation of Evt801 Clinical Data At 15 Biennial Ovarian Cancer Research Symposium

New major risk - Market cap size

Kazia Therapeutics Limited has completed a Follow-on Equity Offering in the amount of $10 million.

Kazia Therapeutics Limited Announces Phase II/III Clinical Trial Results for Paxalisib in Glioblastoma

Kazia Therapeutics Limited Reports Successful Stage 1 Completion of the EVT801 Phase 1 Clinical Trial in Advanced Cancer Patients

Kazia Therapeutics Limited announced that it expects to receive $15 million in funding from Alumni Capital LP

New major risk - Share price stability

New major risk - Financial position

New minor risk - Financial data availability

Kazia Therapeutics Limited Reports Early Conclusion of Clinical Trial After Reaching Primary Endpoint

Kazia Therapeutics Limited Announces Appointment of Board Members

Kazia Therapeutics Limited Announces Executive Changes

New major risk - Revenue and earnings growth

New major risk - Shareholder dilution

Kazia Therapeutics Limited has completed a Follow-on Equity Offering in the amount of $1.981756 million.

Kazia Therapeutics Announces Receipt of Nasdaq Minimum Bid Notification

High number of new and inexperienced directors

Kazia Therapeutics Provides Preliminary Update from Ongoing Phase 2 Study of Paxalisib in Primary Cns Lymphoma

Kazia Therapeutics Limited Announces Clinical Data At ESMO 2023 from Ongoing Phase 1 ESMO Study

Kazia Therapeutics Limited Announces Acceptance of Late-Breaking Abstracts and Oral Presentation of Pnoc022 Clinical Data At 2023 Society for Neuro-Oncology Annual Meeting

Kazia Therapeutics Limited, Annual General Meeting, Nov 08, 2023

Kazia Therapeutics Limited Announces Change to Board of Directors

Kazia Therapeutics Limited Appoints John Friend as Managing Director

Kazia Therapeutics Limited has completed a Follow-on Equity Offering in the amount of AUD 4.5 million.

Kazia Therapeutics Limited Receives Fast Track Designation from FDA for Treatment of Solid Tumor Brain Metastases Harboring PI3K Pathway Mutations in Combination with Radiation Therapy

Kazia Therapeutics Limited Announces Phase II Clinical Study to Investigate Paxalisib in Recurrent/Progressive IDH-Mutant Grade 2 & 3 Glioma

Kazia Therapeutics Limited Appoints Ms. Ebru Davidson to its Board

Kazia gains on FDA’s rare pediatric disease designation for childhood cancer therapy

Shareholder Returns