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Gilead Sciences (GILD): Assessing Valuation After Major Trodelvy Breast Cancer Breakthrough and HIV Advances

Reviewed by Kshitija Bhandaru
Gilead Sciences (GILD) has been drawing attention after releasing promising Phase 3 results for Trodelvy. The results show a marked extension in progression-free survival among metastatic triple-negative breast cancer patients. The company also highlighted advances in HIV prevention and treatment.
See our latest analysis for Gilead Sciences.
All this news comes as Gilead’s share price has surged by nearly 34% year-to-date, with momentum clearly building on the back of major new clinical data, product launches, and ongoing pipeline progress. Long-term holders have been rewarded as well, with a 47% total shareholder return over the past year, showing renewed enthusiasm for the company’s outlook.
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But with shares near their all-time high, some investors may wonder whether Gilead’s strong run still leaves room for upside. Others may question if expectations for future growth are already fully reflected in the stock price.
Most Popular Narrative: 2.5% Undervalued
Compared to Gilead’s last close at $123.11, the most popular narrative estimates a fair value of $126.31. This suggests analysts see further room for shares to climb. The story behind this latest valuation centers on Gilead’s evolving product mix and ramped-up innovation.
The launch and scaling of innovative products (Yeztugo, Trodelvy first-line, Livdelzi) position Gilead to deliver a more favorable product mix and premium pricing, driving higher gross margins and improving long-term earnings trajectory as portfolio diversification reduces overexposure to legacy products.
Want to know the forward-looking math behind this call? The narrative leans on optimistic revenue growth, rising profit margins, and bold future earnings expectations. What specific analyst assumptions make up this fair value? Click through to uncover the numbers and logic powering the valuation.
Result: Fair Value of $126.31 (UNDERVALUED)
Have a read of the narrative in full and understand what's behind the forecasts.
However, policy changes impacting drug pricing or increased competition for HIV treatments could quickly alter Gilead’s growth trajectory. This underscores the importance of ongoing vigilance.
Find out about the key risks to this Gilead Sciences narrative.
Build Your Own Gilead Sciences Narrative
If you have your own perspective or want to see how the facts stack up from a different angle, why not put together your own narrative in just a few minutes? Do it your way
A great starting point for your Gilead Sciences research is our analysis highlighting 4 key rewards and 2 important warning signs that could impact your investment decision.
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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.
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About NasdaqGS:GILD
Gilead Sciences
A biopharmaceutical company, discovers, develops, and commercializes medicines in the areas of unmet medical need in the United States, Europe, and internationally.
Established dividend payer and good value.
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