TransMedics (TMDX) Valuation: How Recent Upward Earnings Revisions and Bullish Momentum Might Shape Investor Returns

Simply Wall St

TransMedics Group (TMDX) shares have seen renewed investor interest after the company’s earnings estimates were revised upward several times, with no downgrades reported. The stock also climbed above important technical moving averages, which has fueled optimism.

See our latest analysis for TransMedics Group.

Momentum appears to be building for TransMedics Group. After climbing past key moving averages and posting a 5.74% 1-day share price return, the stock has attracted the attention of investors, with its year-to-date share price return rising an impressive 96.89%. Recent participation in high-profile industry conferences and ongoing positive earnings revisions contribute to growing optimism in the company's long-term growth story, and the 1-year total shareholder return is a strong 72.19%.

If TransMedics’ remarkable run has you curious about other innovators in the space, why not explore more healthcare standouts with our See the full list for free.

But with such rapid gains and optimistic projections, is TransMedics stock still trading at a discount, or have all those future growth expectations already been priced in? Could there still be a buying opportunity here, or is the market ahead of itself?

Most Popular Narrative: 7.7% Undervalued

TransMedics Group’s most popular valuation narrative assigns a fair value of $141.91 per share, which stands above the recent closing price of $130.93. With the stock still trading below this projected fair value, investors are eyeing the potential upside predicted by this widely followed perspective.

Expansion into new organ types (notably kidney) and next-generation product launches (Gen 3 OCS platforms for heart, lung, and liver) are expected to materially grow TransMedics' total addressable market, improve product mix, and support higher average selling prices, benefiting earnings and longer-term net margins.

Read the complete narrative.

Want to see what’s really fueling that higher target price? The narrative hints at game-changing growth levers, including future launches, new markets, and financial improvements that could reshape expectations. Ready for the inside story behind these bold projections?

Result: Fair Value of $141.91 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, execution risks remain if clinical trials stumble or if competitive platforms improve. Either of these factors could challenge TransMedics’ projected growth story.

Find out about the key risks to this TransMedics Group narrative.

Another View: Multiples Tell a Different Story

While the fair value model suggests TransMedics is undervalued, a look through the lens of price-to-earnings paints a more cautious picture. The company's current ratio of 48.8x is well above both the industry’s 27.7x and the peer average of 37.8x. It also exceeds its fair ratio of 27.6x. This sizable gap could signal some valuation risk if the market’s optimism fades. Are future earnings expectations running too hot, or could profit momentum justify this premium moving forward?

See what the numbers say about this price — find out in our valuation breakdown.

NasdaqGM:TMDX PE Ratio as at Nov 2025

Build Your Own TransMedics Group Narrative

If you have a different perspective or want a personalized take, you can dig into the numbers and craft your interpretation in just minutes with our Do it your way

A good starting point is our analysis highlighting 3 key rewards investors are optimistic about regarding TransMedics Group.

Looking for More Investment Ideas?

Miss out on the next big winner if you stick to just one stock. Widen your search with these smart investment opportunities and boost your market confidence today.

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

Valuation is complex, but we're here to simplify it.

Discover if TransMedics Group might be undervalued or overvalued with our detailed analysis, featuring fair value estimates, potential risks, dividends, insider trades, and its financial condition.

Access Free Analysis

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com