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Schrödinger, Inc.NasdaqGS:SDGR Stock Report

Market Cap US$969.9m
Share Price
US$13.13
US$21.38
38.6% undervalued intrinsic discount
1Y-44.4%
7D11.0%
Portfolio Value
View

Schrödinger, Inc.

NasdaqGS:SDGR Stock Report

Market Cap: US$969.9m

Schrödinger (SDGR) Stock Overview

Develops physics-based computational platform that enables discovery of novel molecules for drug development and materials applications in the United States, the Asia-Pacific, Europe, Middle East, Africa, and internationally. More details

SDGR fundamental analysis
Snowflake Score
Valuation2/6
Future Growth1/6
Past Performance0/6
Financial Health6/6
Dividends0/6

SDGR Community Fair Values

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See what 43 others think this stock is worth. Follow their fair value or set your own to get alerts.

Schrödinger, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Schrödinger
Historical stock prices
Current Share PriceUS$13.28
52 Week HighUS$27.63
52 Week LowUS$10.95
Beta1.58
1 Month Change16.59%
3 Month Change-1.56%
1 Year Change-44.39%
3 Year Change-49.94%
5 Year Change-77.50%
Change since IPO-53.63%

Recent News & Updates

Analysis Article May 08

Analysts Have Lowered Expectations For Schrödinger, Inc. (NASDAQ:SDGR) After Its Latest Results

Shareholders of Schrödinger, Inc. ( NASDAQ:SDGR ) will be pleased this week, given that the stock price is up 11% to...
Narrative Update May 01

SDGR: Hosted Shift And 2026 Outlook Will Shape Risk Reward Balance

Narrative Update Overview Schrödinger's consensus analyst price target has moved to $13, with recent cuts from $18 and $24 as analysts factor in near term revenue pressure from the shift toward hosted software and adjust assumptions around growth, profitability, and valuation multiples. Analyst Commentary Recent research points to a more cautious tone around Schrödinger, with price targets moving lower as analysts factor in execution risk around the shift toward hosted software and its impact on reported revenue and valuation assumptions.
Seeking Alpha Apr 22

Schrodinger: AI Threat Is Looming Large (Rating Downgrade)

Summary The capabilities of AI continue to grow, which is pressuring Schrödinger's share price. This situation has been exacerbated by recent weak software growth and guidance for 2026. While AI displacement risk is real, potential downstream value suggests deep undervaluation for SDGR. Despite this, there is no clear near-term catalyst that will shift investor sentiment and boost the stock. Read the full article on Seeking Alpha

Recent updates

Analysis Article May 08

Analysts Have Lowered Expectations For Schrödinger, Inc. (NASDAQ:SDGR) After Its Latest Results

Shareholders of Schrödinger, Inc. ( NASDAQ:SDGR ) will be pleased this week, given that the stock price is up 11% to...
Narrative Update May 01

SDGR: Hosted Shift And 2026 Outlook Will Shape Risk Reward Balance

Narrative Update Overview Schrödinger's consensus analyst price target has moved to $13, with recent cuts from $18 and $24 as analysts factor in near term revenue pressure from the shift toward hosted software and adjust assumptions around growth, profitability, and valuation multiples. Analyst Commentary Recent research points to a more cautious tone around Schrödinger, with price targets moving lower as analysts factor in execution risk around the shift toward hosted software and its impact on reported revenue and valuation assumptions.
Seeking Alpha Apr 22

Schrodinger: AI Threat Is Looming Large (Rating Downgrade)

Summary The capabilities of AI continue to grow, which is pressuring Schrödinger's share price. This situation has been exacerbated by recent weak software growth and guidance for 2026. While AI displacement risk is real, potential downstream value suggests deep undervaluation for SDGR. Despite this, there is no clear near-term catalyst that will shift investor sentiment and boost the stock. Read the full article on Seeking Alpha
Narrative Update Apr 17

SDGR: Hosted Software Shift And 2026 Booking Timing Will Drive Upside

Analysts have trimmed Schrödinger's implied fair value from $23.50 to $21.38 to reflect recent reductions in Street price targets as they recalibrate revenue growth expectations and factor in mixed views on the near term impact of the shift toward more hosted software. Analyst Commentary Recent research shows a clear reset in expectations around Schrödinger, with several firms lowering price targets while reassessing how the growing mix of hosted software could influence reported results and investor sentiment.
Narrative Update Apr 03

SDGR: Hosted Software Transition Will Set Up 2026 Demand Reappraisal

Narrative Update on Schrödinger The average analyst price target for Schrödinger has reset toward $13, with recent cuts from $33 to $24, $28 to $25, $24 to $20, and $18 to $13 reflecting concerns about near term revenue pressure from the shift toward hosted software and ongoing debate about appropriate valuation multiples, even as analysts highlight stable demand indicators and maintain a mix of Buy, Overweight, Equal Weight, and Neutral views. Analyst Commentary Recent research on Schrödinger shows a cluster of price target resets and overall cautious positioning, even where ratings remain constructive.
Narrative Update Mar 20

SDGR: Sector Pressures And Hosted Software Shift Will Reset 2026 Expectations

Schrödinger's analyst fair value has shifted from $18.00 to $13.00 as analysts recalibrated near term revenue growth assumptions, margin expectations, and future P/E multiples in light of recent price target reductions and commentary around hosted software and sector-wide valuation pressures. Analyst Commentary Recent Street research on Schrödinger has turned more cautious, with several bearish analysts trimming price targets as they reassess near term revenue recognition, margin outlook, and appropriate P/E multiples for the stock.
Narrative Update Mar 06

SDGR: Hosted Software Shift Will Reshape Future Profitability Profile

Analysts have trimmed their average price target for Schrödinger from $27.30 to $23.50. The revision reflects updated views on the revenue impact of the shift toward hosted software, revised profit margin expectations, and a higher assumed future P/E multiple.
Narrative Update Feb 19

SDGR: Sector Recovery And 2026 Guidance Will Reset Growth Expectations

Analysts have modestly reset their views on Schrödinger, with Street price targets clustering in an $18 to $25 range after recent revisions. This reflects a blend of sector-wide multiple compression, cautious sentiment on biotech and a preference for companies with clearer multi year growth frameworks.
Narrative Update Feb 05

SDGR: Sector Recovery And 2026 Guidance Are Expected To Drive Upside

Analysts now set an average price target of about US$19 for Schrödinger, a roughly US$1 move from earlier blended expectations, reflecting mixed but generally constructive views that balance reduced targets from some firms with modest increases and new coverage focused on clearer multi year growth frameworks and sector recovery potential. Analyst Commentary Recent research updates on Schrödinger cluster around price targets in the high teens to mid twenties, with several firms adjusting their views as they recalibrate expectations for healthcare IT and small to mid cap biotech going into 2026.
Analysis Article Feb 04

With A 26% Price Drop For Schrödinger, Inc. (NASDAQ:SDGR) You'll Still Get What You Pay For

Unfortunately for some shareholders, the Schrödinger, Inc. ( NASDAQ:SDGR ) share price has dived 26% in the last thirty...
Narrative Update Jan 22

SDGR: Sector Recovery Themes And 2026 Guidance Will Shape Balanced Outlook

Analysts have nudged their average price target on Schrödinger slightly higher to about $19, reflecting modestly stronger long term growth and margin assumptions, even as some firms trim near term targets to $24 and $25 and others initiate or lift targets around $18 to $19. Analyst Commentary Recent research on Schrödinger clusters around a tight band of price targets, mostly between $18 and $25, with differing opinions on how much upside remains relative to the current share price.
Narrative Update Jan 07

SDGR: Future Outlook Will Balance Software Guidance With Catalyst Partnership Progress

Analysts have adjusted their price expectations for Schrödinger, citing updated assumptions around discount rates, revenue growth, profit margins, and a significantly higher future P/E multiple as the key drivers behind the revised target range and risk profile. What's in the News Schrödinger updated its financial guidance for the year ending December 31, 2025, with software revenue growth now expected in a range of 8% to 13%, compared with a prior range of 10% to 15% (Corporate Guidance).
Narrative Update Dec 16

SDGR: Future Outlook Will Hinge On Software Momentum And Pipeline Data

Analysts have modestly reduced their price target on Schrödinger from $19.00 to $18.00 per share, reflecting a more cautious view on near term revenue growth and margins amid limited visibility on software growth and pending validation from early stage pipeline data. Analyst Commentary Recent research commentary underscores a more balanced but guarded stance on Schrödinger, with the stock viewed as needing further proof points on both its software growth trajectory and its internal pipeline productivity.
Analysis Article Nov 23

What You Can Learn From Schrödinger, Inc.'s (NASDAQ:SDGR) P/S After Its 27% Share Price Crash

Schrödinger, Inc. ( NASDAQ:SDGR ) shareholders won't be pleased to see that the share price has had a very rough month...
Analysis Article Nov 08

Analysts Are Updating Their Schrödinger, Inc. (NASDAQ:SDGR) Estimates After Its Third-Quarter Results

As you might know, Schrödinger, Inc. ( NASDAQ:SDGR ) just kicked off its latest third-quarter results with some very...
Narrative Update Aug 16

Pipeline And Predictive Toxicology Will Unlock Future Success

Schrödinger’s consensus price target has been revised downward to $28.20, reflecting analyst concerns over disappointing progress in its proprietary drug portfolio and broader sector headwinds, partially offset by steady performance in its software business. Analyst Commentary Bearish analysts expressed concerns over disappointing updates from Schrodinger's proprietary drug portfolio, particularly lackluster progress in its early Phase 1 assets, which were previously anticipated to attract significant partner interest.
Analysis Article Apr 28

Schrödinger, Inc. (NASDAQ:SDGR) Looks Just Right With A 33% Price Jump

Schrödinger, Inc. ( NASDAQ:SDGR ) shareholders would be excited to see that the share price has had a great month...
Analysis Article Mar 27

An Intrinsic Calculation For Schrödinger, Inc. (NASDAQ:SDGR) Suggests It's 46% Undervalued

Key Insights The projected fair value for Schrödinger is US$38.44 based on 2 Stage Free Cash Flow to Equity Current...
User avatar
New Narrative Mar 23

Partnerships With Novartis And Lilly Will Strengthen Future Prospects

Expansion in software and partnerships with pharmaceutical giants is expected to boost revenue and margins significantly.
Seeking Alpha Mar 02

Schrödinger: Still Waiting On A Catalyst

Summary Schrödinger's Q4 2024 results and 2025 guidance were solid, yet the company's share price remains low due to ongoing losses. Cash burn is likely to moderate going forward, as investments in the company's internal pipeline have now stabilized. Regardless, cash burn concerns are misplaced, as Schrödinger has demonstrated that it can manage its liquidity position through things like partnerships and licensing. Schrödinger appears attractively priced given the strength of its software business and growing drug discovery business. Despite this, I don't expect the stock to rerate until the company has meaningful clinical success. Read the full article on Seeking Alpha
Analysis Article Feb 28

What Does Schrödinger, Inc.'s (NASDAQ:SDGR) Share Price Indicate?

Schrödinger, Inc. ( NASDAQ:SDGR ), is not the largest company out there, but it saw a double-digit share price rise of...
Seeking Alpha Feb 15

Schrödinger: An Interesting Investment With Immense Potential

Summary SDGR has reported financial losses in five of the last six years. In 2025, the company will report the results of its three experimental drugs that are in Phase 1 of clinical trials. The results will clarify the perspective of SDGR. The losses that SDGR has reported were due to the expenses that it has incurred to implement trials of its three experimental drugs. Read the full article on Seeking Alpha
Analysis Article Jan 25

Market Participants Recognise Schrödinger, Inc.'s (NASDAQ:SDGR) Revenues Pushing Shares 25% Higher

Schrödinger, Inc. ( NASDAQ:SDGR ) shares have continued their recent momentum with a 25% gain in the last month alone...
Analysis Article Jan 06

Companies Like Schrödinger (NASDAQ:SDGR) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Seeking Alpha Nov 21

Schrödinger: Positive Signs Despite The Share Price Decline

Summary Schrödinger's growth was soft in the third quarter, and the company's losses continue to grow due to investments in internal programs. Operating expenses are expected to level out going forward, though, and Schrödinger should soon return to YoY growth. Despite short-term investor skepticism, the Novartis deal and progress by partners further validate Schrödinger's approach to drug discovery. While Schrödinger is deeply undervalued and has sufficient cash to continue advancing internal programs, positive clinical data will likely be needed for the stock to rise. Read the full article on Seeking Alpha
Analysis Article Nov 13

Market Participants Recognise Schrödinger, Inc.'s (NASDAQ:SDGR) Revenues Pushing Shares 26% Higher

Schrödinger, Inc. ( NASDAQ:SDGR ) shareholders would be excited to see that the share price has had a great month...
Seeking Alpha Oct 17

Schrödinger's Path Forward: AI, Cash Burn, And Clinical Uncertainty

Summary Schrödinger's stock has fallen 64% since January 2023, driven by missed revenue and EPS targets, despite ongoing AI-powered drug discovery efforts. Financial health remains stable with a current ratio over 2 and a cash runway of approximately 2 years, despite significant net losses and high R&D investments. The company's proprietary pipeline, including SGR-1505 for B-cell malignancies, faces significant competition and must deliver convincing safety and efficacy data. Maintain "hold" rating due to high operational and financial risks, despite promising AI prospects and a more palatable valuation. Read the full article on Seeking Alpha
Analysis Article Sep 27

Market Participants Recognise Schrödinger, Inc.'s (NASDAQ:SDGR) Revenues

Schrödinger, Inc.'s ( NASDAQ:SDGR ) price-to-sales (or "P/S") ratio of 6.9x may look like a poor investment opportunity...
Seeking Alpha Aug 06

Schrodinger: More Drug Discovery Validation

Summary Schrodinger reported robust software and drug discovery revenue in the second quarter. Lilly's planned multi-billion-dollar acquisition of Morphic also provides another validation point for Schrodinger's approach to drug discovery. Schrodinger's stock remains under pressure due to mounting losses and market jitters though. While Schrodinger is undervalued, investors will likely need to see more evidence of drug discovery success before the stock moves higher. Read the full article on Seeking Alpha
Analysis Article Aug 05

Here's Why We're Watching Schrödinger's (NASDAQ:SDGR) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Analysis Article Jun 12

We Think The Compensation For Schrödinger, Inc.'s (NASDAQ:SDGR) CEO Looks About Right

Key Insights Schrödinger's Annual General Meeting to take place on 18th of June Total pay for CEO Ramy Farid includes...
Seeking Alpha May 07

Schrödinger: More Pharmaceutical Than Software

Summary Market conditions remain tough, which is weighing on demand for both Schrödinger's software and drug discovery services. Investors continue to punish Schrödinger's investments in drug discovery, despite the company progressing drug candidates into clinical trials. While Schrödinger's valuation is attractive, investors are focused on the company's large losses and modest growth. Clinical success may be required before Schrödinger's various ventures are appropriately valued. Read the full article on Seeking Alpha
Analysis Article May 02

Schrödinger, Inc. (NASDAQ:SDGR) Not Flying Under The Radar

When you see that almost half of the companies in the Healthcare Services industry in the United States have...
Analysis Article Mar 01

Schrödinger, Inc. (NASDAQ:SDGR) Analysts Just Cut Their EPS Forecasts Substantially

Market forces rained on the parade of Schrödinger, Inc. ( NASDAQ:SDGR ) shareholders today, when the analysts...
Seeking Alpha Mar 01

Schrodinger: Conservative Guidance Sets The Stock Up For A Solid 2024

Summary Schrodinger reported strong Q4 2023 results, but weak guidance for 2024, causing a significant drop in the share price. The demand environment continues to impact the software business, with growth amongst smaller customers particularly soft. Losses associated with the drug discovery business could continue to weigh on the stock in the near-term. As Schrodinger's proprietary and collaboration programs progress through clinical trials, the stock price is more likely to reflect the true value of Schrodinger's various activities. Read the full article on Seeking Alpha
Analysis Article Feb 28

Is Now An Opportune Moment To Examine Schrödinger, Inc. (NASDAQ:SDGR)?

While Schrödinger, Inc. ( NASDAQ:SDGR ) might not have the largest market cap around , it led the NASDAQGS gainers with...
Analysis Article Feb 01

The Price Is Right For Schrödinger, Inc. (NASDAQ:SDGR) Even After Diving 26%

The Schrödinger, Inc. ( NASDAQ:SDGR ) share price has softened a substantial 26% over the previous 30 days, handing...
Analysis Article Dec 18

Schrödinger, Inc.'s (NASDAQ:SDGR) P/S Still Appears To Be Reasonable

When close to half the companies in the Healthcare Services industry in the United States have price-to-sales ratios...

Shareholder Returns

SDGRUS Healthcare ServicesUS Market
7D11.0%-0.2%2.1%
1Y-44.4%-36.5%30.6%

Return vs Industry: SDGR underperformed the US Healthcare Services industry which returned -37% over the past year.

Return vs Market: SDGR underperformed the US Market which returned 31% over the past year.

Price Volatility

Is SDGR's price volatile compared to industry and market?
SDGR volatility
SDGR Average Weekly Movement7.5%
Healthcare Services Industry Average Movement10.6%
Market Average Movement7.2%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: SDGR has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: SDGR's weekly volatility (7%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
1990850Ramy Faridwww.schrodinger.com

Schrödinger, Inc., together with its subsidiaries, develops physics-based computational platform that enables discovery of novel molecules for drug development and materials applications in the United States, the Asia-Pacific, Europe, Middle East, Africa, and internationally. The company operates in two segments, Software and Drug Discovery. The Software segment sells its software to transform molecular discovery for life sciences and materials science industries.

Schrödinger, Inc. Fundamentals Summary

How do Schrödinger's earnings and revenue compare to its market cap?
SDGR fundamental statistics
Market capUS$969.87m
Earnings (TTM)-US$103.48m
Revenue (TTM)US$254.91m
3.9x
P/S Ratio
-9.6x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
SDGR income statement (TTM)
RevenueUS$254.91m
Cost of RevenueUS$113.87m
Gross ProfitUS$141.04m
Other ExpensesUS$244.52m
Earnings-US$103.48m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-1.38
Gross Margin55.33%
Net Profit Margin-40.60%
Debt/Equity Ratio0%

How did SDGR perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/07 17:06
End of Day Share Price 2026/05/07 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Schrödinger, Inc. is covered by 19 analysts. 7 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Gaurav GoparajuBerenberg
Clarence PowellBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research