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Spero Therapeutics, Inc. Stock Price

NasdaqGS:SPRO Community·US$148.8m Market Cap
  • 1 Narratives written by author
  • 0 Comments on narratives written by author
  • 27 Fair Values set on narratives written by author

SPRO Share Price Performance

US$2.54
-0.26 (-9.29%)
US$4.00
Fair Value
US$2.54
-0.26 (-9.29%)
36.5% undervalued intrinsic discount
US$4.00
Fair Value
Price US$2.54
AnalystConsensusTarget US$4.00

SPRO Community Narratives

·
Fair Value US$4 36.5% undervalued intrinsic discount

Positive Phase III Efficacy Will Unlock Expanded Antibiotic Markets

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22users have followed this narrative
US$4
36.5% undervalued intrinsic discount
Profit Margin
16.06%
Future PE
129.09x
Price in 2028
US$4.8

Trending Discussion

Updated Narratives

SPRO logo

Positive Phase III Efficacy Will Unlock Expanded Antibiotic Markets

Fair Value: US$4 36.5% undervalued intrinsic discount
22 users have set this as their fair value
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Snowflake Analysis

Flawless balance sheet with proven track record.

1 Risk
2 Rewards

Spero Therapeutics, Inc. Key Details

US$61.2m

Revenue

US$27.8m

Cost of Revenue

US$33.4m

Gross Profit

US$18.2m

Other Expenses

US$15.2m

Earnings

Last Reported Earnings
Mar 31, 2026
Next Reporting Earnings
n/a
0.26
54.61%
24.90%
0%
View Full Analysis

About SPRO

Founded
2013
Employees
25
CEO
Esther Rajavelu
WebsiteView website
sperotherapeutics.com

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company’s product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

Recent SPRO News & Updates

Seeking Alpha Jun 08

Spero Therapeutics: Approval Upside, Commercial Friction (Initiating Hold)

Summary I initiate Spero Therapeutics at hold, citing excessive reliance on tebipenem HBr and limited pipeline optionality. SPRO’s near-term value hinges on tebipenem’s FDA approval, but commercial adoption faces niche market constraints and challenging royalty economics. Regulatory risk remains after the prior CRL; while pivotal data de-risks approval, upside appears priced in, and commercial execution by GSK is critical. Valuation is supported by cash runway into 2028, but binary regulatory and commercial risks limit conviction for a more aggressive rating. Read the full article on Seeking Alpha

Recent updates

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