SEHK:6855
SEHK:6855Biotechs

Ascentage Pharma (SEHK:6855) Is Up 6.9% After FDA Clears IND For First BTK PROTAC Degrader

Ascentage Pharma Group International recently reported that the US FDA has cleared its IND application for APG-3288, a next-generation BTK-targeted PROTAC degrader, allowing the company to begin clinical trials in patients with relapsed or refractory B-cell malignancies. This step not only extends Ascentage Pharma's efforts in targeted protein degradation but also responds to the medical need created by resistance to existing BTK inhibitors. We will now examine how FDA clearance for...
SEHK:1277
SEHK:1277Oil and Gas

Kinetic Development Group (SEHK:1277) Is Up 17.2% After Securing Long-Term Sierra Leone Rutile Rights – Has The Bull Case Changed?

In December 2025, the board of Kinetic Development Group announced that its Sierra Leone subsidiary Metal Mining had signed cooperation agreements with Minenet to develop and operate a rutile project in Rotifunk, securing exclusive rights to explore, mine, process, and sell heavy sand minerals within a designated 50 square kilometre area until 2049. This long-term project, involving about US$18,000,000 of initial investment, plans up to five production lines and could materially expand...