공시 • May 02
Nymox Pharmaceutical Corporation announced delayed 20-F filing On 05/01/2025, Nymox Pharmaceutical Corporation announced that they will be unable to file their next 20-F by the deadline required by the SEC. 공시 • Mar 27
Nymox Pharmaceutical Corporation Reports Victory in Bahamas Litigation Against Terminated Ex-Employees – Court Awards Costs and Damages Nymox Pharmaceutical Corporation reported that the Bahamas Supreme Court has issued a formal Order officially putting an end to the Bahamas litigation brought by terminated ex-employees. The Order also awards to Nymox its costs incurred in defending the ill-conceived lawsuit, as well as damages Nymox has suffered as a result of the litigation. The Court order states the following: The Interim Injunction Order is set aside; The damages caused to the Company shall be assessed by a Registrar and paid by the Claimants (the persons who filed the lawsuit); and The Claimants shall pay the Company’s net costs for the entire Action. This is the first of more than one action by and between the Company and Randall Lanham, (former General Counsel for Nymox), Chris Riley, (former short-term CFO), Richard Cutler (former external Counsel and member of Board), and their financial backers. 공시 • Sep 26
Nymox Pharmaceutical Corporation Announces Submission of New Marketing Authorization Application Submission for NYMOZARFEX (TM) for BPH Nymox Pharmaceutical Corporation announced that a new formal submission has been made by the company in the U.K. for Nymozarfex (TM) for the treatment of benign prostatic hyperplasia (BPH). The Marketing Authorization Application (MAA) was submitted to the U.K. Medicines & Healthcare products Regulatory Agency (MHRA). The new submission includes England, Wales, Scotland and Northern Ireland. The company will provide further information, including with respect to other submissions for Nymozarfex (TM), when the information becomes available. 공시 • Sep 08
The Nasdaq Stock Market to Delist the Common Stock of Nymox Pharmaceutical The Nasdaq Stock Market announced that it will delist the common stock of Nymox Pharmaceutical Corporation. Nymox Pharmaceutical Corporation’s securities were suspended on July 7, 2023, and have not traded on Nasdaq since that time. 공시 • Aug 03
Nymox Pharmaceutical Corporation announced that it expects to receive $2 million in funding Nymox Pharmaceutical Corporation announced a private placement of 2,000,000 common shares at a price of $1.00 per share for gross proceeds of $2,000,000 on August 2, 2023. The company will also issue 500,000 warrants. The transaction included participation from James G. Robinson, an independent director of the company. The investment will close in the upcoming days after the customary formalities are completed. 공시 • Jul 26
Nymox Pharmaceutical Corporation Reports Successful New NYMOZARFEX (TM) Long-Term Prostate Cancer Treatment Clinical Trial Results Nymox Pharmaceutical Corporation announced important new long-term clinical trial results from the company's 146 patient NX03-0040 NYMOZARFEX (TM) U.S. study for low grade localized prostate cancer. New long-term follow-up data from the prospective randomized clinical trial of NYMOZARFEX (TM) for low grade early prostate cancer has indicated that there is strong statistically significant benefit from the treatment compared to controls when all available patient outcomes were included from 18 months to as long as up to >10 years after treatment. These additional 5 to 10-year data points add to the 5-year data that was published in the peer review World Journal of Urology in 2020 (World J Urol 38, 3101–3111 (2020). All clinical trial sites that were still open were contacted for follow-up data on the prostate cancer status of all available patients. A full effort was made to reach all possible subjects. The outcome comparisons showed greatly reduced percentages of subjects treated with NYMOZARFEX (TM) who had progressed by either cancer grade worsening or by prostate cancer surgery, radiotherapy, or chemotherapy; and which remained overall strongly statistically significant compared to the study's randomized controls (p<.01). This unique and successful study is the world's first and only long-term prospective randomized controlled study of an intraprostatic molecular injectable treatment for low-grade localized prostate cancer to have been accomplished. The new data represents the longest term data available from this major study. Study NX03-0040 was undertaken starting in 2012 at investigational sites across the U.S. with 146 men with the biopsy confirmed diagnosis of Grade Group1 prostate cancer. NYMOZARFEX (TM) was administered by a single painless injection directly into the prostate in a relatively simple procedure requiring several minutes or less in an office setting without sedation or anesthesia, and guided by routine ultrasound. NYMOZARFEX (TM) was injected into the area of the prostate where the cancer was previously detected prior to enrollment in NX03-0040. The patients were then biopsied after 6 weeks and then every 18 months, along with serial PSA measurements and long-term follow-up. All subjects with 18 months or more follow-up were compared with the inclusion of follow-up data from up to 10 years or more after a single injection of NYMOZARFEX (TM). For the patients where investigational sites were closed or where patients for unrelated reasons were no longer available, the last known status reports were included if they were 18 months or longer. For any subject with a worsening (increase) in grade of prostate cancer on biopsy; or with prostate cancer surgery, or radiotherapy or chemotherapy, they were included regardless of time after study treatment, and were counted in the calculation as treatment failures. The data shows that the number of patients with one focal injection of NYMOZARFEX (TM) 15 mg directed at the tumor had significantly less progression to more advanced cancer or to major cancer treatments, than the randomized control subjects followed in the study. Low grade localized prostate cancer (Gleason 3+3; T1c) is a very common treatment problem. The Nymox study reported involves patients with initially Gleason grade 3+3 or lower. These patients are found to have these tumors by biopsy which is usually instituted after finding abnormalities in PSA levels, and/or after abnormal digital rectal examination of the prostate, and/or after the patient has experienced lower urinary tract symptoms or other changes. Low grade localized prostate cancer represents a therapeutic challenge. Because of its slow growth and low initial level of malignancy, urologists and patients can be reluctant to proceed to invasive surgical treatments or radiotherapy due to the unpleasant and often permanent side effects these treatments cause in the genitourinary tract, such as sexual functional issues and/or urinary issues. Eventually if and when the tumor progresses, invasive surgical and/or radiotherapeutic procedures become necessary, with greater risk due to the progression. Occasionally the tumors become highly malignant after variable lengths of time. These risks cause understandable anxieties and distress and many men prefer to advance to invasive therapy before running these risks of higher grade cancers. It is widely acknowledged that a treatment like NYMOZARFEX (TM) that can destroy or ablate the low grade cancers of the prostate without the dreaded side effects and morbidities, would be an important benefit for these patients. Prostate cancer is the most commonly diagnosed cancer in men, other than skin cancer, and is the second leading cause of cancer death for men. Approximately 50% of prostate cancers are initially considered low risk. One of the major problems with the main current prostate treatments for localized prostate cancer (radical prostatectomy, external beam radiation, brachytherapy) is the relatively high incidence of serious sexual and other problems post- treatment. In 9 studies, NYMOZARFEX (TM) treatment has been shown to have a negligible significant adverse effect profile post-treatment and no significant adverse effects on sexual or other functions or testosterone levels. Leading urologists have long recognized the unmet need for prostate cancer treatments that can contribute to improved outcomes for their patients together with reduced side effects and stresses that may have significantly impact on quality of life. The goal of NYMOZARFEX (TM) injectable is to allow for an initial and less toxic treatment for low-risk prostate cancer patients, achieving the benefits of molecular ablation with minimal risk of side effects. For many patients, this treatment combined with surveillance would be extremely helpful for the unpleasant and persistent uncertainties, anxieties, and psychological/emotional burdens associated with only selecting active surveillance. 