공시 • Mar 10
Aptorum Group Limited and DiamiR Biosciences Corp Announce Publication of MicroRNA-Based Glioblastoma Biomarkers Using Blood Plasma Specimens Aptorum Group Limited and DiamiR Biosciences Corp. announced the publication of a paper by Giliberto, et. al. titled "Development of microRNA-Based Glioblastoma Biomarkers Using Blood Plasma Specimens" in Diagnostics, a peer-reviewed journal focused on clinical diagnostics and biomarker research. This study, conducted in collaboration with clinical researchers at the Perelman School of Medicine at the University of Pennsylvania, demonstrates the feasibility of detecting glioblastoma (GBM) — the most aggressive and lethal form of brain cancer — through a minimally invasive blood plasma test. The research identifies specific microRNA signatures in blood plasma that show significant promise as non-invasive biomarkers for glioblastoma diagnosis and monitoring. GBM is among the deadliest of all human cancers, with a median survival of fewer than 15 months following diagnosis. Current diagnostic approaches rely on invasive surgical biopsies or costly imaging procedures. DiamiR’s microRNA platform represents a potential paradigm shift, one that the company believe will enable earlier detection and improve patient monitoring through a simple blood draw. 공시 • Feb 09
Aptorum Group Limited, Annual General Meeting, Mar 10, 2026 Aptorum Group Limited, Annual General Meeting, Mar 10, 2026, at 09:00 China Standard Time. Location: 17/f., guangdong investment tower, 148 connaught road central, Hong Kong New Risk • Dec 18
New major risk - Market cap size The company's market capitalization is less than US$10m. Market cap: US$8.96m This is considered a major risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Major Risks Shareholders have been substantially diluted in the past year (45% increase in shares outstanding). Revenue is less than US$1m. Market cap is less than US$10m (US$8.96m market cap). Minor Risk Share price has been volatile over the past 3 months (14% average weekly change). 공시 • Oct 11
Aptorum Group Limited has filed a Follow-on Equity Offering in the amount of $2 million. Aptorum Group Limited has filed a Follow-on Equity Offering in the amount of $2 million.
Security Name: Class A Ordinary Shares
Security Type: Common Stock
Securities Offered: 1,000,000
Price\Range: $2
Transaction Features: Registered Direct Offering 공시 • Oct 10
Aptorum Group Limited Announces Board and Executive Appointments Aptorum Group Limited announced the addition of Dr. Laura A. Philips to its board of directors as an independent director at closing of the merger with DiamiR Biosciences Corp. Dr. Philips is the co-founder, President, and Chief Executive Officer of Spheryx Inc., a technology company developing holographic microscopic techniques for a broad range of applications in areas including the pharmaceutical industry, semiconductor manufacturing, cosmetics, consumer products, quality assurance, and process control. In addition to co-founding Spheryx in 2014, Dr. Philips has served on the Boards of Directors of multiple private and public life sciences companies, including WellGen Inc., Delcath Systems, and China Yongxin Pharmaceuticals. From 2003-2006, Dr. Philips was COO and Chief Financial Officer at NexGenix Pharmaceuticals. She held a variety of executive positions at Corning Incorporated from 1997-2002. Dr. Philips served in the Clinton Administration both as a Fellow in the White House Office of Science and Technology Policy and as a Presidential Appointee in the position of Senior Policy Advisor to Secretary Ronald Brown in the Department of Commerce. Dr. Philips holds a Ph.D. in Chemistry from the University of California, Berkeley, and an MBA from Cornell University, and was on the Faculty of Cornell University in the Department of Chemistry from 1987-1993. As was previously announced on July 16, 2025, Aptorum Group and DiamiR entered into a definitive agreement for an all-stock merger transaction. As a result of this transaction and subject to stockholder approval of both companies and customary closing conditions, DiamiR will become a wholly-owned subsidiary of Aptorum Group upon consummation of the merger. The transaction is expected to close in the fourth quarter of 2025. Once the merger is closed, Dr. Kira Sheinerman, DiamiR’s co-founder and director, will be joining the combined company board as a director, and Dr. Alidad Mireskandari, DiamiR’s Chief Executive Officer, will be taking an observer seat on the board and joining the combined company as its President and Chief Operating Officer. Dr. Mireskandari has extensive life sciences industry experience with a focus on molecular diagnostic test development and commercialization, including regulatory and reimbursement expertise. Dr. Mireskandari most recently served as Chief Development Officer of Interpace Biosciences from 2013 to 2022, and prior to that as President & Chief Executive Officer of JS Genetics from 2009 to 2013. From 2000 to 2009, Dr. Mireskandari was a hedge fund manager in charge of Life Sciences trading portfolios of Nomura Securities, BNP Paribas and Raeburn Advisors. Dr. Mireskandari holds a Ph.D. in Genetics from George Washington University and an MBA from the University of Michigan Ross School of Business. Dr. Sheinerman is DiamiR’s co-founder and Executive Director. Since November 2015, she has served as a Managing Director, Healthcare Investment Banking at H.C. Wainwright & Co., where she works on financial and strategic transactions for growth life sciences companies. Previously, she was a Managing Director of Healthcare Investment Banking at Rodman & Renshaw from 2005 to 2012. From 2015 through 2018 she served as the founding co-chair of Alzheimer’s Association Business Consortium. Dr. Sheinerman received her Ph.D. in Biomedical Sciences from Mount Sinai School of Medicine for her work on molecular mechanisms of Alzheimer’s Disease. Dr. Sheinerman also holds an Honors MBA from the Zicklin School of Business, Baruch College/CUNY. 공시 • Aug 21
DiamiR Biosciences and Aptorum Group Announce New York State Approval for DiamiR's APOE Genotyping Test DiamiR Biosciences Corp. and Aptorum Group Limited announced that DiamiR received a Clinical Laboratory Evaluation Program (CLEP) Test Approval for its APOE Genotyping test from the New York State Department of Health (NYSDOH). This milestone allows DiamiR to offer its validated APOE Genotyping molecular testing in a variety of biological samples, such as blood, buccal swab, saliva, and tissue, through its Clinical Laboratory Improvement Amendments (CLIA) certified, College of American Pathologists (CAP) accredited clinical laboratory by licensed healthcare providers in New York State and nationwide. New York State DOH CLEP is known for having stringent validation standards for laboratory-developed tests (LDTs). Clinical laboratories testing biospecimens from New York residents must obtain a clinical laboratory permit from NYSDOH to help ensure the accuracy and reliability of clinical tests. 