Gubra（GUBR.F）株式概要グブラ社（Gubra A/S）はバイオテクノロジー企業で、ヨーロッパ、北米、および国際的な代謝性・線維性疾患の前臨床受託研究およびペプチドベースの創薬に注力している。 詳細GUBR.F ファンダメンタル分析スノーフレーク・スコア評価2/6将来の成長5/6過去の実績0/6財務の健全性5/6配当金0/6報酬当社が推定した公正価値より75.9%で取引されている 収益は年間7.94%増加すると予測されています リスク分析株式の流動性は非常に低い すべてのリスクチェックを見るGUBR.F Community Fair Values Create NarrativeSee what others think this stock is worth. Follow their fair value or set your own to get alerts.NEW463,747 membersJoin community and earn perksGain real feedbackFrom our editorial team, personally. Not silence.Grow your followingReal investors. The kind who actually invest, not scroll past.Unlock free accessFree premium subscription for consistent and quality authors.Learn moreCreate NarrativeBLINRODA463,747 investors already sharing narrativesYour Fair ValueUS$Current PriceUS$60.15312.6% 割高 内在価値ディスカウントGrowth estimate overAnnual revenue growth rate5 Yearstime period%/yrDecreaseIncreasePastFuture-45m427m2016201920222025202620282031Revenue DKK 426.6mEarnings DKK 54.8mAdvancedSet Fair ValueView all narrativesGubra A/S 競合他社Cytek BiosciencesSymbol: NasdaqGS:CTKBMarket cap: US$605.1mMesa LaboratoriesSymbol: NasdaqGS:MLABMarket cap: US$667.2mCryoportSymbol: NasdaqCM:CYRXMarket cap: US$826.1mAzentaSymbol: NasdaqGS:AZTAMarket cap: US$1.6b価格と性能株価の高値、安値、推移の概要Gubra過去の株価現在の株価DKK 60.1552週高値DKK 102.4152週安値DKK 60.15ベータ0.501ヶ月の変化0%3ヶ月変化n/a1年変化n/a3年間の変化n/a5年間の変化n/aIPOからの変化-35.96%最新ニュースお知らせ • Jul 28Gubra A/S Announces Initiation Of Ambitious Phase 1/2a Clinical Trial Of Lead Asset GUB-UCN2 In ObesityGubra A/S announced the initiation of the first-in-human trial of GUB-UCN2, the company’s next mega program, with the first participant completing the first visit. The Phase 1/2a clinical trial is designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GUB-UCN2, with a particular focus on muscle volume and muscle function. The Phase 1/2a trial will enroll a total of approximately 188 healthy participants and individuals living with obesity, with and without related comorbidities. The trial consists of three parts: a single ascending dose (SAD) component, a multiple ascending dose (MAD) component, and a multiple dose (MD) component with a treatment duration of up to 16 weeks. The trial will investigate GUB-UCN2 as both a standalone therapy and in combination with incretin-based therapy for obesity. Data from the trial are expected to be released on a sequential basis, with initial data from the SAD study in healthy volunteers, including safety, tolerability, and pharmacokinetic assessments, expected in the first half of 2027. The trial is strategically designed to maximize asset value by generating multidimensional clinical data early in development and preparing the regulatory path for further development. GUB-UCN2 has delivered strong and comprehensive preclinical data. Results have shown that GUB-UCN2 substantially and selectively lowers fat mass and increases muscle mass when administered alone and in combination with incretin-based therapy. In combination with a GLP-1 receptor agonist, GUB-UCN2 completely prevented the lean mass loss typically seen with GLP-1 receptor agonist-based therapies and enhanced fat mass reduction. GUB-UCN2 also reversed lean mass loss after prior GLP-1 exposure, positioning it as both a protective and restorative therapy in treatment combination regimens. Beyond body composition, UCN2 has delivered improvements of cardiac and renal function in preclinical models. UCN2 (Urocortin 2), is a 38 amino acid neuropeptide that selectively binds to the corticotropin-releasing hormone receptor 2 (CRHR2). Activation of CRHR2 by UCN2 induces a reprogramming of skeletal muscle toward an exercise-like phenotype, leading to a favorable shift in body composition characterized by increased muscle mass and reduced fat mass. Mechanistically, UCN2 acts directly on CRHR2 receptors expressed in skeletal muscle, where it stimulates muscle growth and enhances performance. This effect is mediated in part through increased protein synthesis within muscle tissue. In parallel, UCN2 reduces intramuscular fat accumulation, contributing to improved muscle quality and metabolic efficiency. Additionally, UCN2 enhances insulin sensitivity in skeletal muscle, further supporting metabolic health and glucose homeostasis.お知らせ • Jun 16Gubra Announces Appointment of Lena Moran-Adams as Group General Counsel, Effective June 16, 2026Gubra announced the appointment of Lena Moran-Adams as the company’s new Group General Counsel, effective June 16, 2026. Lena Moran-Adams joined Gubra as its new Group General Counsel responsible for driving legal strategy and execution across its business. Prior to joining Gubra, she held senior legal leadership roles at Telix Pharmaceuticals (Group General Counsel), Gilead Sciences (Head of Legal & Business Conduct, Intercontinental Region), Novartis (Global Head Legal) and Bristol Myers Squibb (Regional Senior Legal Counsel). Lena is admitted to practice law across three continents and brings more than 25 years of experience leading legal, compliance, intellectual property and corporate governance strategy teams across multiple regions and globally. Her background spans multiple practice areas, jurisdictions, and business models, ranging from start-up biotechnology companies to multinational blue-chip biopharmaceutical organizations.お知らせ • Mar 04Gubra A/S, Annual General Meeting, Mar 26, 2026Gubra A/S, Annual General Meeting, Mar 26, 2026, at 10:00 Romance Standard Time. Location: horsholm kongevej 11b, 2970, Denmarkお知らせ • Feb 19+ 1 more updateGubra A/S to Report First Half, 2026 Results on Aug 20, 2026Gubra A/S announced that they will report first half, 2026 results on Aug 20, 2026お知らせ • Jan 08Amylyx Pharmaceuticals, Inc. Announces Nomination of Amx0318 as A Novel, Long-Acting Glp-1 Receptor AntagonistAmylyx Pharmaceuticals, Inc. announced the selection of AMX0318, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist, as a development candidate for post-bariatric hypoglycemia (PBH) and other rare diseases. AMX0318 was identified through a research collaboration with Gubra A/S. AMX0318 has completed extensive preclinical evaluation, including stability, solubility, potency, in vivo pharmacokinetics and pharmacodynamics, and in vivo tolerability studies. Amylyx expects the program to advance into investigational new drug (IND)-enabling studies later this year, with an IND targeted for 2027, pending successful completion of IND-enabling studies. Under the terms of the research collaboration, Gubra is eligible to receive more than $50 million in success-based development and commercialization milestones plus mid-single digit royalties on worldwide net sales. The selection and handover of the development candidate will provide milestone payments of $4 million to Gubra.お知らせ • Jan 05Gubra Announces Executive ChangesGubra announced the appointment of Thomas Langenickel, M.D., as Chief Medical and Development Officer (CMDO) effective January 5, 2026. Dr. Langenickel brings more than two decades of experience in big pharma and biotech, spanning drug discovery, translational medicine, and clinical development. In his new role, he will join Gubra’s Leadership Team and guide the company’s preclinical and clinical development strategy as its pipeline advances toward key milestones. Dr. Langenickel most recently served as Chief Medical Officer at Ethris, where he led the development of early clinical assets in respiratory and infectious diseases. His prior experience includes senior roles at Novartis as Executive Director of Translational Medicine and Profiling, and at Bristol Myers Squibb as Medical Director. He earned his M.D. from Humboldt University of Berlin and completed a postdoctoral fellowship in vascular biology at the National Heart, Lung, and Blood Institute, NIH (USA). Gubra also extends its gratitude to Dr. Mads Axelsen, who retired in December after serving as CMO. His leadership and contributions have been instrumental in shaping Gubra's development organization and supporting the company's growth.最新情報をもっと見るRecent updatesお知らせ • Jul 28Gubra A/S Announces Initiation Of Ambitious Phase 1/2a Clinical Trial Of Lead Asset GUB-UCN2 In ObesityGubra A/S announced the initiation of the first-in-human trial of GUB-UCN2, the company’s next mega program, with the first participant completing the first visit. The Phase 1/2a clinical trial is designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GUB-UCN2, with a particular focus on muscle volume and muscle function. The Phase 1/2a trial will enroll a total of approximately 188 healthy participants and individuals living with obesity, with and without related comorbidities. The trial consists of three parts: a single ascending dose (SAD) component, a multiple ascending dose (MAD) component, and a multiple dose (MD) component with a treatment duration of up to 16 weeks. The trial will investigate GUB-UCN2 as both a standalone therapy and in combination with incretin-based therapy for obesity. Data from the trial are expected to be released on a sequential basis, with initial data from the SAD study in healthy volunteers, including safety, tolerability, and pharmacokinetic assessments, expected in the first half of 2027. The trial is strategically designed to maximize asset value by generating multidimensional clinical data early in development and preparing the regulatory path for further development. GUB-UCN2 has delivered strong and comprehensive preclinical data. Results have shown that GUB-UCN2 substantially and selectively lowers fat mass and increases muscle mass when administered alone and in combination with incretin-based therapy. In combination with a GLP-1 receptor agonist, GUB-UCN2 completely prevented the lean mass loss typically seen with GLP-1 receptor agonist-based therapies and enhanced fat mass reduction. GUB-UCN2 also reversed lean mass loss after prior GLP-1 exposure, positioning it as both a protective and restorative therapy in treatment combination regimens. Beyond body composition, UCN2 has delivered improvements of cardiac and renal function in preclinical models. UCN2 (Urocortin 2), is a 38 amino acid neuropeptide that selectively binds to the corticotropin-releasing hormone receptor 2 (CRHR2). Activation of CRHR2 by UCN2 induces a reprogramming of skeletal muscle toward an exercise-like phenotype, leading to a favorable shift in body composition characterized by increased muscle mass and reduced fat mass. Mechanistically, UCN2 acts directly on CRHR2 receptors expressed in skeletal muscle, where it stimulates muscle growth and enhances performance. This effect is mediated in part through increased protein synthesis within muscle tissue. In parallel, UCN2 reduces intramuscular fat accumulation, contributing to improved muscle quality and metabolic efficiency. Additionally, UCN2 enhances insulin sensitivity in skeletal muscle, further supporting metabolic health and glucose homeostasis.お知らせ • Jun 16Gubra Announces Appointment of Lena Moran-Adams as Group General Counsel, Effective June 16, 2026Gubra announced the appointment of Lena Moran-Adams as the company’s new Group General Counsel, effective June 16, 2026. Lena Moran-Adams joined Gubra as its new Group General Counsel responsible for driving legal strategy and execution across its business. Prior to joining Gubra, she held senior legal leadership roles at Telix Pharmaceuticals (Group General Counsel), Gilead Sciences (Head of Legal & Business Conduct, Intercontinental Region), Novartis (Global Head Legal) and Bristol Myers Squibb (Regional Senior Legal Counsel). Lena is admitted to practice law across three continents and brings more than 25 years of experience leading legal, compliance, intellectual property and corporate governance strategy teams across multiple regions and globally. Her background spans multiple practice areas, jurisdictions, and business models, ranging from start-up biotechnology companies to multinational blue-chip biopharmaceutical organizations.お知らせ • Mar 04Gubra A/S, Annual General Meeting, Mar 26, 2026Gubra A/S, Annual General Meeting, Mar 26, 2026, at 10:00 Romance Standard Time. Location: horsholm kongevej 11b, 2970, Denmarkお知らせ • Feb 19+ 1 more updateGubra A/S to Report First Half, 2026 Results on Aug 20, 2026Gubra A/S announced that they will report first half, 2026 results on Aug 20, 2026お知らせ • Jan 08Amylyx Pharmaceuticals, Inc. Announces Nomination of Amx0318 as A Novel, Long-Acting Glp-1 Receptor AntagonistAmylyx Pharmaceuticals, Inc. announced the selection of AMX0318, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist, as a development candidate for post-bariatric hypoglycemia (PBH) and other rare diseases. AMX0318 was identified through a research collaboration with Gubra A/S. AMX0318 has completed extensive preclinical evaluation, including stability, solubility, potency, in vivo pharmacokinetics and pharmacodynamics, and in vivo tolerability studies. Amylyx expects the program to advance into investigational new drug (IND)-enabling studies later this year, with an IND targeted for 2027, pending successful completion of IND-enabling studies. Under the terms of the research collaboration, Gubra is eligible to receive more than $50 million in success-based development and commercialization milestones plus mid-single digit royalties on worldwide net sales. The selection and handover of the development candidate will provide milestone payments of $4 million to Gubra.お知らせ • Jan 05Gubra Announces Executive ChangesGubra announced the appointment of Thomas Langenickel, M.D., as Chief Medical and Development Officer (CMDO) effective January 5, 2026. Dr. Langenickel brings more than two decades of experience in big pharma and biotech, spanning drug discovery, translational medicine, and clinical development. In his new role, he will join Gubra’s Leadership Team and guide the company’s preclinical and clinical development strategy as its pipeline advances toward key milestones. Dr. Langenickel most recently served as Chief Medical Officer at Ethris, where he led the development of early clinical assets in respiratory and infectious diseases. His prior experience includes senior roles at Novartis as Executive Director of Translational Medicine and Profiling, and at Bristol Myers Squibb as Medical Director. He earned his M.D. from Humboldt University of Berlin and completed a postdoctoral fellowship in vascular biology at the National Heart, Lung, and Blood Institute, NIH (USA). Gubra also extends its gratitude to Dr. Mads Axelsen, who retired in December after serving as CMO. His leadership and contributions have been instrumental in shaping Gubra's development organization and supporting the company's growth.お知らせ • Jun 27Gubra A/S Approves Distribution of Extraordinary Cash DividendsGubra A/S at its EGM held on June 27, 2025, approved a distribution of extraordinary cash dividends to the Company's shareholders in the amount of DKK 1 billion, corresponding to DKK 61.2 per share of a nominal value of DKK 1.お知らせ • Jun 03Gubra A/S Proposes Extraordinary Cash DividendGubra A/S board of directors proposed that the extraordinary general meeting to be held on 27 June 2025, approves a distribution of extraordinary cash dividends to the Company's shareholders in the amount of DKK 1,000 million, corresponding to DKK 61.2 (rounded) per share of a nominal value of DKK 1.お知らせ • Apr 04Gubra A/S Approves Board ChangesGubra A/S in its annual general meeting held on 3 April, 2025, Henriette Dræbye Rosenquist did not stand for re-election. The Board extends heartfelt Henriette for her significant contributions wishing her all the best in her new endeavours. The Board welcomes Gubra Co-Founder and Scientific Advisor Niels Vrang's re-entry to the board and Claudia Mitchell as new members of the Board. Their collective experience in biotech innovation, research, and entrepreneurship will be a valuable asset to the next chapters in the company's growth journey. Monika Lessl, previously serving as a Board member, has been appointed as the new Chair, succeeding Jacob Jelsing, who remains an active member of the Board. As internationally experienced pharma and life science executive with more than 25 years of R&D and Innovation leadership, Monika brings visionary leadership and deep insight into innovation and sustainability - two key pillars of Gubra's mission.お知らせ • Mar 11Gubra A/S, Annual General Meeting, Apr 03, 2025Gubra A/S, Annual General Meeting, Apr 03, 2025, at 10:00 Romance Standard Time. Location: horsholm kongevej 11b, dk-2970, horsholm, Denmarkお知らせ • Mar 10Gubra A/S Announces Board ChangesGubra A/S announced Henriette Dræbye Rosenquist does not stand for re-election. The board of directors notes that Jacob Jelsing will step down as chair of the board of directors in connection with the annual general meeting but will continue to serve as an ordinary member of the board of directors.お知らせ • Feb 27+ 1 more updateGubra A/S to Report First Half, 2025 Results on Aug 21, 2025Gubra A/S announced that they will report first half, 2025 results on Aug 21, 2025お知らせ • Jan 15Gubra Appoints Anne-Marie Levy Rasmussen as Chief Operating OfficerGubra announced the appointment of Anne-Marie Levy Rasmussen as the company's new Chief Operating Officer (COO). Anne-Marie brings a strong international experience and track record from global pharma companies such as GlaxoSmithKline and Bavarian Nordic within operational leadership, scaling and establishment of solid governance routines in complex settings. Most recently as Head of Global Commercial Operations at Bavarian Nordic. As COO in Gubra, Anne-Marie will be member of the Executive Management Team and be responsible for overseeing the company's operational strategy, optimizing processes, and driving efficiency across departments and key projects. Her extensive background within leadership, scaling and system integration with new digital approaches positions her well to contribute to Gubra's continued growth and innovation. Anne-Marie's theoretical background is a MSc Physics from University of Copenhagen.株主還元GUBR.FUS Life SciencesUS 市場7D0%5.3%-2.1%1Yn/a28.1%18.8%株主還元を見る業界別リターン: GUBR.FがUS Life Sciences業界に対してどのようなパフォーマンスを示したかを判断するにはデータが不十分です。リターン対市場: GUBR.F US市場に対してどのようなパフォーマンスを示したかを判断するにはデータが不十分です。価格変動Is GUBR.F's price volatile compared to industry and market?GUBR.F volatilityGUBR.F Average Weekly Movementn/aLife Sciences Industry Average Movement7.8%Market Average Movement7.2%10% most volatile stocks in US Market16.3%10% least volatile stocks in US Market3.1%安定した株価: GUBR.Fの株価は、 US市場と比較して過去 3 か月間で変動しています。時間の経過による変動: 過去 1 年間のGUBR.Fのボラティリティの変化を判断するには データが不十分です。会社概要設立従業員CEO（最高経営責任者ウェブサイト2008260Henrik Blouwww.gubra.dkバイオテクノロジー企業であるGubra A/S社は、欧州、北米、および国際的に、代謝性疾患および線維性疾患における前臨床受託研究およびペプチドベースの創薬に注力している。同社は3つのセグメントで事業を展開している：前臨床試験受託事業（CRO）、創薬・提携事業、グブラグリーン。同社は、製薬・バイオテクノロジー業界向けに代謝性・線維性疾患の前臨床研究開発受託サービスを提供するほか、in vivo薬理学、バイオマーカーアッセイ、バイオインフォマティクス、次世代シーケンシング、薬物動態学、人工知能病理学による2D・3D組織学などのサービスを提供している。同社は、肥満症治療薬としてベーリンガーインゲルハイム社、出血性疾患治療薬としてヘマブ社、肥満後の低血糖症やその他の希少疾患治療薬として新規長時間作用型GLP-1受容体拮抗薬を開発するエイミリックス・ファーマシューティカルズ社と提携・共同研究を行っている。Gubra A/Sは2008年に設立され、デンマークのホーホルムを拠点としている。もっと見るGubra A/S 基礎のまとめGubra の収益と売上を時価総額と比較するとどうか。GUBR.F 基礎統計学時価総額US$904.48m収益（TTM）-US$5.66m売上高(TTM)US$41.20m22.0xP/Sレシオ-159.9xPER（株価収益率GUBR.F は割高か？公正価値と評価分析を参照収益と収入最新の決算報告書（TTM）に基づく主な収益性統計GUBR.F 損益計算書（TTM）収益DKK 265.74m売上原価DKK 101.24m売上総利益DKK 164.50mその他の費用DKK 201.00m収益-DKK 36.50m直近の収益報告Dec 31, 2024次回決算日Aug 21, 2025一株当たり利益（EPS）-2.24グロス・マージン61.90%純利益率-13.73%有利子負債／自己資本比率0%GUBR.F の長期的なパフォーマンスは？過去の実績と比較を見るView Valuation企業分析と財務データの現状データ最終更新日（UTC時間）企業分析2025/08/03 17:55終値2025/05/06 00:00収益2024/12/31年間収益2024/12/31データソース企業分析に使用したデータはS&P Global Market Intelligence LLC のものです。本レポートを作成するための分析モデルでは、以下のデータを使用しています。データは正規化されているため、ソースが利用可能になるまでに時間がかかる場合があります。パッケージデータタイムフレーム米国ソース例会社財務10年損益計算書キャッシュ・フロー計算書貸借対照表SECフォーム10-KSECフォーム10-Qアナリストのコンセンサス予想+プラス3年予想財務アナリストの目標株価アナリストリサーチレポートBlue Matrix市場価格30年株価配当、分割、措置ICEマーケットデータSECフォームS-1所有権10年トップ株主インサイダー取引SECフォーム4SECフォーム13Dマネジメント10年リーダーシップ・チーム取締役会SECフォーム10-KSECフォームDEF 14A主な進展10年会社からのお知らせSECフォーム8-K* 米国証券を対象とした例であり、非米国証券については、同等の規制書式および情報源を使用。特に断りのない限り、すべての財務データは1年ごとの期間に基づいていますが、四半期ごとに更新されます。これは、TTM（Trailing Twelve Month）またはLTM（Last Twelve Month）データとして知られています。詳細はこちら。分析モデルとスノーフレークこのレポートを生成するために使用した分析モデルの詳細は、当社のGitHubページでご覧いただけます。また、レポートの活用方法に関するガイドやYouTubeのチュートリアルも用意しています。シンプリー・ウォールストリート分析モデルを設計・構築した世界トップクラスのチームについてご紹介します。業界およびセクターの指標私たちの業界とセクションの指標は、Simply Wall Stによって6時間ごとに計算されます。アナリスト筋Gubra A/S 2 これらのアナリストのうち、弊社レポートのインプットとして使用した売上高または利益の予想を提出したのは、 。アナリストの投稿は一日中更新されます。3 アナリスト機関Rune DahlDNB CarnegieJesper IlsøeDNB CarnegieRajan SharmaGoldman Sachs
お知らせ • Jul 28Gubra A/S Announces Initiation Of Ambitious Phase 1/2a Clinical Trial Of Lead Asset GUB-UCN2 In ObesityGubra A/S announced the initiation of the first-in-human trial of GUB-UCN2, the company’s next mega program, with the first participant completing the first visit. The Phase 1/2a clinical trial is designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GUB-UCN2, with a particular focus on muscle volume and muscle function. The Phase 1/2a trial will enroll a total of approximately 188 healthy participants and individuals living with obesity, with and without related comorbidities. The trial consists of three parts: a single ascending dose (SAD) component, a multiple ascending dose (MAD) component, and a multiple dose (MD) component with a treatment duration of up to 16 weeks. The trial will investigate GUB-UCN2 as both a standalone therapy and in combination with incretin-based therapy for obesity. Data from the trial are expected to be released on a sequential basis, with initial data from the SAD study in healthy volunteers, including safety, tolerability, and pharmacokinetic assessments, expected in the first half of 2027. The trial is strategically designed to maximize asset value by generating multidimensional clinical data early in development and preparing the regulatory path for further development. GUB-UCN2 has delivered strong and comprehensive preclinical data. Results have shown that GUB-UCN2 substantially and selectively lowers fat mass and increases muscle mass when administered alone and in combination with incretin-based therapy. In combination with a GLP-1 receptor agonist, GUB-UCN2 completely prevented the lean mass loss typically seen with GLP-1 receptor agonist-based therapies and enhanced fat mass reduction. GUB-UCN2 also reversed lean mass loss after prior GLP-1 exposure, positioning it as both a protective and restorative therapy in treatment combination regimens. Beyond body composition, UCN2 has delivered improvements of cardiac and renal function in preclinical models. UCN2 (Urocortin 2), is a 38 amino acid neuropeptide that selectively binds to the corticotropin-releasing hormone receptor 2 (CRHR2). Activation of CRHR2 by UCN2 induces a reprogramming of skeletal muscle toward an exercise-like phenotype, leading to a favorable shift in body composition characterized by increased muscle mass and reduced fat mass. Mechanistically, UCN2 acts directly on CRHR2 receptors expressed in skeletal muscle, where it stimulates muscle growth and enhances performance. This effect is mediated in part through increased protein synthesis within muscle tissue. In parallel, UCN2 reduces intramuscular fat accumulation, contributing to improved muscle quality and metabolic efficiency. Additionally, UCN2 enhances insulin sensitivity in skeletal muscle, further supporting metabolic health and glucose homeostasis.
お知らせ • Jun 16Gubra Announces Appointment of Lena Moran-Adams as Group General Counsel, Effective June 16, 2026Gubra announced the appointment of Lena Moran-Adams as the company’s new Group General Counsel, effective June 16, 2026. Lena Moran-Adams joined Gubra as its new Group General Counsel responsible for driving legal strategy and execution across its business. Prior to joining Gubra, she held senior legal leadership roles at Telix Pharmaceuticals (Group General Counsel), Gilead Sciences (Head of Legal & Business Conduct, Intercontinental Region), Novartis (Global Head Legal) and Bristol Myers Squibb (Regional Senior Legal Counsel). Lena is admitted to practice law across three continents and brings more than 25 years of experience leading legal, compliance, intellectual property and corporate governance strategy teams across multiple regions and globally. Her background spans multiple practice areas, jurisdictions, and business models, ranging from start-up biotechnology companies to multinational blue-chip biopharmaceutical organizations.
お知らせ • Mar 04Gubra A/S, Annual General Meeting, Mar 26, 2026Gubra A/S, Annual General Meeting, Mar 26, 2026, at 10:00 Romance Standard Time. Location: horsholm kongevej 11b, 2970, Denmark
お知らせ • Feb 19+ 1 more updateGubra A/S to Report First Half, 2026 Results on Aug 20, 2026Gubra A/S announced that they will report first half, 2026 results on Aug 20, 2026
お知らせ • Jan 08Amylyx Pharmaceuticals, Inc. Announces Nomination of Amx0318 as A Novel, Long-Acting Glp-1 Receptor AntagonistAmylyx Pharmaceuticals, Inc. announced the selection of AMX0318, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist, as a development candidate for post-bariatric hypoglycemia (PBH) and other rare diseases. AMX0318 was identified through a research collaboration with Gubra A/S. AMX0318 has completed extensive preclinical evaluation, including stability, solubility, potency, in vivo pharmacokinetics and pharmacodynamics, and in vivo tolerability studies. Amylyx expects the program to advance into investigational new drug (IND)-enabling studies later this year, with an IND targeted for 2027, pending successful completion of IND-enabling studies. Under the terms of the research collaboration, Gubra is eligible to receive more than $50 million in success-based development and commercialization milestones plus mid-single digit royalties on worldwide net sales. The selection and handover of the development candidate will provide milestone payments of $4 million to Gubra.
お知らせ • Jan 05Gubra Announces Executive ChangesGubra announced the appointment of Thomas Langenickel, M.D., as Chief Medical and Development Officer (CMDO) effective January 5, 2026. Dr. Langenickel brings more than two decades of experience in big pharma and biotech, spanning drug discovery, translational medicine, and clinical development. In his new role, he will join Gubra’s Leadership Team and guide the company’s preclinical and clinical development strategy as its pipeline advances toward key milestones. Dr. Langenickel most recently served as Chief Medical Officer at Ethris, where he led the development of early clinical assets in respiratory and infectious diseases. His prior experience includes senior roles at Novartis as Executive Director of Translational Medicine and Profiling, and at Bristol Myers Squibb as Medical Director. He earned his M.D. from Humboldt University of Berlin and completed a postdoctoral fellowship in vascular biology at the National Heart, Lung, and Blood Institute, NIH (USA). Gubra also extends its gratitude to Dr. Mads Axelsen, who retired in December after serving as CMO. His leadership and contributions have been instrumental in shaping Gubra's development organization and supporting the company's growth.
お知らせ • Jul 28Gubra A/S Announces Initiation Of Ambitious Phase 1/2a Clinical Trial Of Lead Asset GUB-UCN2 In ObesityGubra A/S announced the initiation of the first-in-human trial of GUB-UCN2, the company’s next mega program, with the first participant completing the first visit. The Phase 1/2a clinical trial is designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of GUB-UCN2, with a particular focus on muscle volume and muscle function. The Phase 1/2a trial will enroll a total of approximately 188 healthy participants and individuals living with obesity, with and without related comorbidities. The trial consists of three parts: a single ascending dose (SAD) component, a multiple ascending dose (MAD) component, and a multiple dose (MD) component with a treatment duration of up to 16 weeks. The trial will investigate GUB-UCN2 as both a standalone therapy and in combination with incretin-based therapy for obesity. Data from the trial are expected to be released on a sequential basis, with initial data from the SAD study in healthy volunteers, including safety, tolerability, and pharmacokinetic assessments, expected in the first half of 2027. The trial is strategically designed to maximize asset value by generating multidimensional clinical data early in development and preparing the regulatory path for further development. GUB-UCN2 has delivered strong and comprehensive preclinical data. Results have shown that GUB-UCN2 substantially and selectively lowers fat mass and increases muscle mass when administered alone and in combination with incretin-based therapy. In combination with a GLP-1 receptor agonist, GUB-UCN2 completely prevented the lean mass loss typically seen with GLP-1 receptor agonist-based therapies and enhanced fat mass reduction. GUB-UCN2 also reversed lean mass loss after prior GLP-1 exposure, positioning it as both a protective and restorative therapy in treatment combination regimens. Beyond body composition, UCN2 has delivered improvements of cardiac and renal function in preclinical models. UCN2 (Urocortin 2), is a 38 amino acid neuropeptide that selectively binds to the corticotropin-releasing hormone receptor 2 (CRHR2). Activation of CRHR2 by UCN2 induces a reprogramming of skeletal muscle toward an exercise-like phenotype, leading to a favorable shift in body composition characterized by increased muscle mass and reduced fat mass. Mechanistically, UCN2 acts directly on CRHR2 receptors expressed in skeletal muscle, where it stimulates muscle growth and enhances performance. This effect is mediated in part through increased protein synthesis within muscle tissue. In parallel, UCN2 reduces intramuscular fat accumulation, contributing to improved muscle quality and metabolic efficiency. Additionally, UCN2 enhances insulin sensitivity in skeletal muscle, further supporting metabolic health and glucose homeostasis.
お知らせ • Jun 16Gubra Announces Appointment of Lena Moran-Adams as Group General Counsel, Effective June 16, 2026Gubra announced the appointment of Lena Moran-Adams as the company’s new Group General Counsel, effective June 16, 2026. Lena Moran-Adams joined Gubra as its new Group General Counsel responsible for driving legal strategy and execution across its business. Prior to joining Gubra, she held senior legal leadership roles at Telix Pharmaceuticals (Group General Counsel), Gilead Sciences (Head of Legal & Business Conduct, Intercontinental Region), Novartis (Global Head Legal) and Bristol Myers Squibb (Regional Senior Legal Counsel). Lena is admitted to practice law across three continents and brings more than 25 years of experience leading legal, compliance, intellectual property and corporate governance strategy teams across multiple regions and globally. Her background spans multiple practice areas, jurisdictions, and business models, ranging from start-up biotechnology companies to multinational blue-chip biopharmaceutical organizations.
お知らせ • Mar 04Gubra A/S, Annual General Meeting, Mar 26, 2026Gubra A/S, Annual General Meeting, Mar 26, 2026, at 10:00 Romance Standard Time. Location: horsholm kongevej 11b, 2970, Denmark
お知らせ • Feb 19+ 1 more updateGubra A/S to Report First Half, 2026 Results on Aug 20, 2026Gubra A/S announced that they will report first half, 2026 results on Aug 20, 2026
お知らせ • Jan 08Amylyx Pharmaceuticals, Inc. Announces Nomination of Amx0318 as A Novel, Long-Acting Glp-1 Receptor AntagonistAmylyx Pharmaceuticals, Inc. announced the selection of AMX0318, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist, as a development candidate for post-bariatric hypoglycemia (PBH) and other rare diseases. AMX0318 was identified through a research collaboration with Gubra A/S. AMX0318 has completed extensive preclinical evaluation, including stability, solubility, potency, in vivo pharmacokinetics and pharmacodynamics, and in vivo tolerability studies. Amylyx expects the program to advance into investigational new drug (IND)-enabling studies later this year, with an IND targeted for 2027, pending successful completion of IND-enabling studies. Under the terms of the research collaboration, Gubra is eligible to receive more than $50 million in success-based development and commercialization milestones plus mid-single digit royalties on worldwide net sales. The selection and handover of the development candidate will provide milestone payments of $4 million to Gubra.
お知らせ • Jan 05Gubra Announces Executive ChangesGubra announced the appointment of Thomas Langenickel, M.D., as Chief Medical and Development Officer (CMDO) effective January 5, 2026. Dr. Langenickel brings more than two decades of experience in big pharma and biotech, spanning drug discovery, translational medicine, and clinical development. In his new role, he will join Gubra’s Leadership Team and guide the company’s preclinical and clinical development strategy as its pipeline advances toward key milestones. Dr. Langenickel most recently served as Chief Medical Officer at Ethris, where he led the development of early clinical assets in respiratory and infectious diseases. His prior experience includes senior roles at Novartis as Executive Director of Translational Medicine and Profiling, and at Bristol Myers Squibb as Medical Director. He earned his M.D. from Humboldt University of Berlin and completed a postdoctoral fellowship in vascular biology at the National Heart, Lung, and Blood Institute, NIH (USA). Gubra also extends its gratitude to Dr. Mads Axelsen, who retired in December after serving as CMO. His leadership and contributions have been instrumental in shaping Gubra's development organization and supporting the company's growth.
お知らせ • Jun 27Gubra A/S Approves Distribution of Extraordinary Cash DividendsGubra A/S at its EGM held on June 27, 2025, approved a distribution of extraordinary cash dividends to the Company's shareholders in the amount of DKK 1 billion, corresponding to DKK 61.2 per share of a nominal value of DKK 1.
お知らせ • Jun 03Gubra A/S Proposes Extraordinary Cash DividendGubra A/S board of directors proposed that the extraordinary general meeting to be held on 27 June 2025, approves a distribution of extraordinary cash dividends to the Company's shareholders in the amount of DKK 1,000 million, corresponding to DKK 61.2 (rounded) per share of a nominal value of DKK 1.
お知らせ • Apr 04Gubra A/S Approves Board ChangesGubra A/S in its annual general meeting held on 3 April, 2025, Henriette Dræbye Rosenquist did not stand for re-election. The Board extends heartfelt Henriette for her significant contributions wishing her all the best in her new endeavours. The Board welcomes Gubra Co-Founder and Scientific Advisor Niels Vrang's re-entry to the board and Claudia Mitchell as new members of the Board. Their collective experience in biotech innovation, research, and entrepreneurship will be a valuable asset to the next chapters in the company's growth journey. Monika Lessl, previously serving as a Board member, has been appointed as the new Chair, succeeding Jacob Jelsing, who remains an active member of the Board. As internationally experienced pharma and life science executive with more than 25 years of R&D and Innovation leadership, Monika brings visionary leadership and deep insight into innovation and sustainability - two key pillars of Gubra's mission.
お知らせ • Mar 11Gubra A/S, Annual General Meeting, Apr 03, 2025Gubra A/S, Annual General Meeting, Apr 03, 2025, at 10:00 Romance Standard Time. Location: horsholm kongevej 11b, dk-2970, horsholm, Denmark
お知らせ • Mar 10Gubra A/S Announces Board ChangesGubra A/S announced Henriette Dræbye Rosenquist does not stand for re-election. The board of directors notes that Jacob Jelsing will step down as chair of the board of directors in connection with the annual general meeting but will continue to serve as an ordinary member of the board of directors.
お知らせ • Feb 27+ 1 more updateGubra A/S to Report First Half, 2025 Results on Aug 21, 2025Gubra A/S announced that they will report first half, 2025 results on Aug 21, 2025
お知らせ • Jan 15Gubra Appoints Anne-Marie Levy Rasmussen as Chief Operating OfficerGubra announced the appointment of Anne-Marie Levy Rasmussen as the company's new Chief Operating Officer (COO). Anne-Marie brings a strong international experience and track record from global pharma companies such as GlaxoSmithKline and Bavarian Nordic within operational leadership, scaling and establishment of solid governance routines in complex settings. Most recently as Head of Global Commercial Operations at Bavarian Nordic. As COO in Gubra, Anne-Marie will be member of the Executive Management Team and be responsible for overseeing the company's operational strategy, optimizing processes, and driving efficiency across departments and key projects. Her extensive background within leadership, scaling and system integration with new digital approaches positions her well to contribute to Gubra's continued growth and innovation. Anne-Marie's theoretical background is a MSc Physics from University of Copenhagen.
