Korro Bio（KRRO）株式概要コーロ・バイオ社はバイオ医薬品会社であり、米国において希少疾患や蔓延性の高い疾患の治療のため、RNA編集に基づく遺伝子医薬品の発見、開発、商業化に従事している。 詳細KRRO ファンダメンタル分析スノーフレーク・スコア評価2/6将来の成長2/6過去の実績0/6財務の健全性6/6配当金0/6報酬収益は年間62.8%増加すると予測されています リスク分析過去1年間で株主の希薄化は大幅に進んだ 今後3年間の収益は年平均12.4%減少すると予測されている。 現在は利益が出ておらず、今後3年間で利益が出る見込みはない US市場と比較した過去 3 か月間の株価の変動+2 さらなるリスクすべてのリスクチェックを見るKRRO Community Fair Values Create NarrativeSee what 8 others think this stock is worth. Follow their fair value or set your own to get alerts.NEW489,177 membersJoin community and earn perksGain real feedbackFrom our editorial team, personally. Not silence.Grow your followingReal investors. The kind who actually invest, not scroll past.Unlock free accessFree premium subscription for consistent and quality authors.Learn moreCreate NarrativeINBLROAG489,177 investors already sharing narrativesYour Fair ValueUS$Current PriceUS$13.65415.1% 割高 内在価値ディスカウントGrowth estimate overAnnual revenue growth rate5 Yearstime period%/yrDecreaseIncreasePastFuture-194m44m2016201920222025202620282031Revenue US$43.9mEarnings US$8.1mAdvancedSet Fair ValueView all narrativesKorro Bio, Inc. 競合他社Keros TherapeuticsSymbol: NasdaqGM:KROSMarket cap: US$215.3mInvivydSymbol: NasdaqGM:IVVDMarket cap: US$257.0mCapForceSymbol: OTCPK:CFORMarket cap: US$204.3mNovaBridge BiosciencesSymbol: NasdaqGM:NBPMarket cap: US$230.1m価格と性能株価の高値、安値、推移の概要Korro Bio過去の株価現在の株価US$13.6552週高値US$55.8952週安値US$5.20ベータ2.11ヶ月の変化5.57%3ヶ月変化-2.50%1年変化4.28%3年間の変化n/a5年間の変化n/aIPOからの変化-11.82%最新ニュースRecent Insider Transactions • Jun 18Senior VP recently sold US$72k worth of stockOn the 16th of June, Jeffrey Cerio sold around 7k shares on-market at roughly US$10.83 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. In the last 3 months, there was an even bigger sale from another insider worth US$197k. Insiders have been net sellers, collectively disposing of US$376k more than they bought in the last 12 months.Recent Insider Transactions Derivative • Jun 17Senior VP notifies of intention to sell stockJeffrey Cerio intends to sell 7k shares in the next 90 days after lodging an Intent To Sell Form on the 16th of June. If the sale is conducted around the recent share price of US$10.83, it would amount to US$72k. As of today, Jeffrey currently holds no shares directly (This sale likely refers to shares that have not yet been received). There has only been one transaction (US$197k sale) from insiders over the last 12 months.分析記事 • Jun 16Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...Seeking Alpha • Jun 15Korro Bio: RNA Editor Plots Way Back After AATD Study Fail - I'm HoldingSummary Korro Bio faces high uncertainty after KRRO-110 failed to meet clinical expectations in AATD, prompting a pipeline overhaul. KRRO-121, targeting hyperammonemia, and KRRO-111, a next-gen AATD candidate, show promising preclinical data but lack clinical proof-of-concept. KRRO's $157.1M cash position funds operations into 2H 2028, but late-stage trials will require additional capital if early data are positive. I am holding KRRO for potential upside but advise caution until Phase 1/2 data derisk the platform; risk/reward is high given competition and unproven clinical efficacy. Read the full article on Seeking AlphaNew Risk • Jun 10New minor risk - Insider sellingThere has been significant insider selling in the company's shares over the past 3 months. Total value of shares sold: US$197k This is considered a minor risk. There are several reasons why an insider may be selling, including to cover a tax obligation or pay for some other expense. However, we generally consider it a negative if insiders have been selling, especially if they do so below the current price. It implies that they considered a lower price to be reasonable. This is a weak signal, but if there is a pattern of unexplained selling, it can be a sign the insider believes the company's stock is overpriced. Note: We only include open market transactions and private dispositions of directly owned stock by individuals, not by corporations or trusts. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 12% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (54% increase in shares outstanding). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$123m net loss in 3 years). Share price has been volatile over the past 3 months (12% average weekly change). Significant insider selling over the past 3 months (US$197k sold). Revenue is less than US$5m (US$3.8m revenue).Recent Insider Transactions • Jun 02CEO, President recently sold US$197k worth of stockOn the 29th of May, Ram Aiyar sold around 15k shares on-market at roughly US$12.98 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. This was the largest sale by an insider in the last 3 months. This was Ram's only on-market trade for the last 12 months.最新情報をもっと見るRecent updatesRecent Insider Transactions • Jun 18Senior VP recently sold US$72k worth of stockOn the 16th of June, Jeffrey Cerio sold around 7k shares on-market at roughly US$10.83 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. In the last 3 months, there was an even bigger sale from another insider worth US$197k. Insiders have been net sellers, collectively disposing of US$376k more than they bought in the last 12 months.Recent Insider Transactions Derivative • Jun 17Senior VP notifies of intention to sell stockJeffrey Cerio intends to sell 7k shares in the next 90 days after lodging an Intent To Sell Form on the 16th of June. If the sale is conducted around the recent share price of US$10.83, it would amount to US$72k. As of today, Jeffrey currently holds no shares directly (This sale likely refers to shares that have not yet been received). There has only been one transaction (US$197k sale) from insiders over the last 12 months.分析記事 • Jun 16Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...Seeking Alpha • Jun 15Korro Bio: RNA Editor Plots Way Back After AATD Study Fail - I'm HoldingSummary Korro Bio faces high uncertainty after KRRO-110 failed to meet clinical expectations in AATD, prompting a pipeline overhaul. KRRO-121, targeting hyperammonemia, and KRRO-111, a next-gen AATD candidate, show promising preclinical data but lack clinical proof-of-concept. KRRO's $157.1M cash position funds operations into 2H 2028, but late-stage trials will require additional capital if early data are positive. I am holding KRRO for potential upside but advise caution until Phase 1/2 data derisk the platform; risk/reward is high given competition and unproven clinical efficacy. Read the full article on Seeking AlphaNew Risk • Jun 10New minor risk - Insider sellingThere has been significant insider selling in the company's shares over the past 3 months. Total value of shares sold: US$197k This is considered a minor risk. There are several reasons why an insider may be selling, including to cover a tax obligation or pay for some other expense. However, we generally consider it a negative if insiders have been selling, especially if they do so below the current price. It implies that they considered a lower price to be reasonable. This is a weak signal, but if there is a pattern of unexplained selling, it can be a sign the insider believes the company's stock is overpriced. Note: We only include open market transactions and private dispositions of directly owned stock by individuals, not by corporations or trusts. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 12% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (54% increase in shares outstanding). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$123m net loss in 3 years). Share price has been volatile over the past 3 months (12% average weekly change). Significant insider selling over the past 3 months (US$197k sold). Revenue is less than US$5m (US$3.8m revenue).Recent Insider Transactions • Jun 02CEO, President recently sold US$197k worth of stockOn the 29th of May, Ram Aiyar sold around 15k shares on-market at roughly US$12.98 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. This was the largest sale by an insider in the last 3 months. This was Ram's only on-market trade for the last 12 months.Recent Insider Transactions Derivative • May 31CEO, President notifies of intention to sell stockRam Aiyar intends to sell 15k shares in the next 90 days after lodging an Intent To Sell Form on the 29th of May. If the sale is conducted around the recent share price of US$12.98, it would amount to US$197k. For the year to December 2022, Ram's total compensation was 20% salary and 80% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since March 2026, Ram has owned 4.61k shares directly. There have been no trades via on-market transactions or options from company insiders in the last 12 months.Major Estimate Revision • May 21Consensus revenue estimates increase by 11%, EPS downgradedThe consensus outlook for fiscal year 2026 has been updated. 2026 revenue forecast increased from US$500.0k to US$560.0k. EPS estimate fell from -US$5.27 to -US$5.45 per share. Biotechs industry in the US expected to see average net income decline 9.8% next year. Consensus price target down from US$20.38 to US$19.89. Share price was steady at US$11.20 over the past week.お知らせ • May 20Korro Bio, Inc. Selects Krro-111 As Development Candidate For The Potential Treatment Of Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. announced the addition of KRRO-111 for the potential treatment of AATD to its pipeline of therapeutic programs in development. KRRO-111 is a proprietary GalNAc-conjugated oligonucleotide that is delivered subcutaneously to the liver cells, where it is engineered to co-opt the hepatocytes’ endogenous Adenosine Deaminase Acting on RNA (ADAR) enzyme and repair a pathogenic single nucleotide variant (SNV) on AAT mRNA to restore production of normal AAT protein. This therapeutic profile along with KRRO-111’s rapid onset of action and titratable dosing to treat this disorder, position the compound as a potential best-in-class candidate. AATD is a genetic disorder most commonly caused by a single missense mutation (G-to-A) in the SERPINA1 gene. Affected adults experience pulmonary emphysema and/or hepatic cirrhosis, as well as end organ manifestations. Greater than 95% of severe clinical cases of AATD are homozygous for the PiZ mutation (known as the PiZZ genotype). There are an estimated 3,400,000 individuals with deficiency allele combinations worldwide. The only current FDA-approved treatment for AATD is augmentation therapy, a once-weekly infusion of pooled human plasma-derived AAT protein, which does not adequately address the manifestations of AATD. In preclinical studies, KRRO-111 demonstrated best-in-class RNA editing where >90% of the AAT transcripts in the liver cells have been corrected, translating into ~90% M-AAT protein. In a repeat-dose study, KRRO-111 (3 mg/kg) was administered to PiZZ mice with a loading phase followed by dosing once every two weeks. KRRO-111 nearly eliminated active Z protein production, reducing non-inclusion Z-AAT by ~95% versus vehicle at both days 28 and 56, reflecting near-complete cessation of Z protein synthesis across the hepatocyte population. Pre-existing aggregates were progressively cleared, with inclusion-associated Z-AAT significantly reduced by approximately 69% at day 28, consistent with autophagic clearance of accumulated protein following successful editing; the residual burden reflects pre-existing disease rather than incomplete editing. By simultaneously increasing circulating M-AAT protein and decreasing pathogenic Z-AAT aggregates in the lung, KRRO-111 has the potential to improve both lung and liver manifestations of the disease. The Company plans to present additional data from its KRRO-111 program at a future scientific meeting or Company-hosted event.Major Estimate Revision • May 14Consensus EPS estimates upgraded to US$5.27 lossThe consensus outlook for fiscal year 2026 has been updated. 2026 losses forecast to reduce from -US$6.75 to -US$5.27 per share. Revenue forecast unchanged from US$500.0k at last update. Biotechs industry in the US expected to see average net income decline 9.8% next year. Consensus price target of US$20.38 unchanged from last update. Share price fell 16% to US$11.20 over the past week.Reported Earnings • May 07First quarter 2026 earnings released: US$1.69 loss per share (vs US$2.49 loss in 1Q 2025)First quarter 2026 results: US$1.69 loss per share (improved from US$2.49 loss in 1Q 2025). Net loss: US$19.6m (loss narrowed 16% from 1Q 2025). Revenue is forecast to grow 60% p.a. on average during the next 3 years, compared to a 21% growth forecast for the Biotechs industry in the US.お知らせ • Apr 17Korro Bio, Inc., Annual General Meeting, Jun 10, 2026Korro Bio, Inc., Annual General Meeting, Jun 10, 2026.Major Estimate Revision • Mar 19Consensus revenue estimates increase by 52,586%The consensus outlook for revenues in fiscal year 2026 has improved. 2026 revenue forecast increased from US$1.27m to US$667.4m. Forecast losses expected to reduce from -US$8.27 to -US$6.75 per share. Biotechs industry in the US expected to see average net income decline 12% next year. Consensus price target up from US$19.33 to US$20.00. Share price fell 3.8% to US$11.06 over the past week.New Risk • Mar 13New major risk - Shareholder dilutionThe company's shareholders have been substantially diluted in the past year. Increase in shares outstanding: 54% This is considered a major risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 9.8% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (54% increase in shares outstanding). Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$108m net loss in 3 years).お知らせ • Mar 09Korro Bio, Inc. announced that it expects to receive $84.996839 million in funding from a group of investorsKorro Bio, Inc announced a private placement and entered into a subscription agreement to issue 4,501,928 common shares at price of $11.11 per share for aggregate proceeds of $50,016,420.08 and 3,148,836 pre-funded warrants at a price of $11.109 for aggregate proceeds of $34,980,419.124, total gross proceeds amounting to $84,996,839.204 on March 9. 2026. The transaction included participation from lead Investor Venrock Healthcare Capital Partners, ADAR1 Capital Management, Affinity Asset Advisors, Balyasny Asset Management, Driehaus Capital Management, Kalehua Capital, Lynx1 Capital Management, Nantahala Capital, and New Enterprise Associates. The pre-funded warrants have an exercise price of $0.001 per underlying share of common stock, are immediately exercisable and have no expiration date. The transaction is expected to close on March 10, 2026 subject to customary closing conditions. The securities will be issued in reliance upon the exemption from securities registration afforded by Section 4(a)(2) of the 1933 Act and not in reliance upon any of the safe harbors set forth in Regulation D promulgated thereunder.Price Target Changed • Feb 12Price target increased by 123% to US$19.33Up from US$8.67, the current price target is an average from 6 analysts. New target price is 64% above last closing price of US$11.76. Stock is down 60% over the past year. The company is forecast to post a net loss per share of US$9.05 next year compared to a net loss per share of US$9.37 last year.Board Change • Feb 12High number of new and inexperienced directorsThere are 12 new directors who have joined the board in the last 3 years. The company's board is composed of: 12 new directors. No experienced directors. No highly experienced directors. Independent Director Ali Behbahani is the most experienced director on the board, commencing their role in 2023. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.お知らせ • Nov 13+ 2 more updatesKorro Bio, Inc. Provides Updates on KRRO-110 in Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. provided a program update for its Phase 1/2a REWRITE clinical trial of KRRO-110 in AATD. The REWRITE Phase 1/2a clinical trial is a two-part single and multiple-dose escalating study evaluating the safety and tolerability of KRRO-110, including healthy adults and clinically stable AATD patients with the PiZZ genotype. Korro has completed all six planned single ascending dose (SAD) healthy volunteer (HV) cohorts. Each HV cohort consisted of six participants, with four receiving active drug and two receiving placebo. Doses of KRRO-110 tested in the HVs (n=24) include 0.04, 0.1, 0.2, 0.4, 0.8 and 1.2 mg/kg, with the primary objective to evaluate safety and tolerability. KRRO-110 is currently being evaluated in two AATD patient cohorts at 0.6 mg/kg (n=3) and 0.8 mg/kg (n=4), with seven patients dosed. The AATD patient cohorts are open label with up to four patients in each cohort. There are currently no plans to complete additional SAD patient cohorts for KRRO-110. Korro is evaluating the totality of the clinical data to evaluate the next steps, if any, for KRRO-110 in the multiple-ascending dose (MAD) portion of the REWRITE clinical trial. KRRO-110 Safety Observations (as of the November 6, 2025 Data Cutoff Date): No dose-limiting toxicities or treatment emergent serious adverse events observed. Mild-to-moderate infusion-related reactions (IRRs) observed in two healthy volunteers at the highest dose of 1.2 mg/kg, two AATD patients at 0.6 mg/kg, and two AATD patients at 0.8 mg/kg. All IRRs resolved within 24 hours post KRRO-110 dosing; intervention was limited to antipyretics and antihistamines. KRRO-110 safety profile is consistent with Lipid Nanoparticles (LNP) infusion-related class effects. KRRO-110 Pharmacodynamic and Pharmacokinetic Observations (as of the November 6, 2025 Data Cutoff Date): Across five AATD patients in the two SAD cohorts evaluable with turbidimetry, the greatest peak total AAT protein was approximately 10 µM and the greatest increase of total AAT protein from baseline was approximately 3 µM. The total AAT protein levels following single-dose administration did not reach the protective threshold of 11 µM. In three of the AATD patients dosed with 0.8 mg/kg evaluable with LC/MS, functional M-AAT protein was observed in each of the patients following administration of KRRO-110. The greatest increase of M-AAT protein from baseline observed at any time point was approximately 2 µM. Functional M-AAT protein lasted up to four weeks for the first patient evaluable with LC/MS, consistent with durability of editing and endogenous M-AAT protein half-life. Pharmacokinetic differences in the components of KRRO-110 in plasma were observed between HV and AATD patients, with apparent faster disassociation of KRRO-110, suggesting variability of this formulation in AATD patients compared to HV following a single dose. No evidence of bystander editing observed to date, suggesting high specificity, based on LC/MS data on M-AAT and Z-AAT. KRRO-110 Regulatory Milestones Validate OPERA Platform Potential: First-ever RNA editing technology to receive Investigational New Drug clearance by the U.S. Food and Drug Administration (FDA) to Korro’s knowledge. Fast Track designation granted by the FDA. Orphan Drug Designation granted by both the FDA and European Medicines Agency.分析記事 • Oct 23Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...お知らせ • Oct 08Korro Bio, Inc. Announces Chief Financial Officer Changes, Effective October 17, 2025On October 7, 2025, Vineet Agarwal announced his intention to resign from his position of Chief Financial Officer of Korro Bio, Inc., or Korro, effective October 17, 2025 to pursue another opportunity. In order to ensure the smooth transition of his functions, Mr. Agarwal has agreed to be available to serve as an advisor for 30 days thereafter. The board of directors of Korro, or the Board, and Korro are incredibly thankful to Mr. Agarwal for his long-standing service at Korro. In light of Mr. Agarwal’s resignation, the Board appointed Dr. Ram Aiyar, President and Chief Executive Officer (principal executive officer), to serve as Korro’s interim Chief Financial Officer and principal financial officer, in addition to his current duties effective from October 17, 2025.Price Target Changed • Sep 10Price target decreased by 8.4% to US$92.33Down from US$101, the current price target is an average from 9 analysts. New target price is 156% above last closing price of US$36.12. Stock is down 7.0% over the past year. The company is forecast to post a net loss per share of US$10.14 next year compared to a net loss per share of US$9.37 last year.Major Estimate Revision • Aug 19Consensus revenue estimates increase by 47%, EPS downgradedThe consensus outlook for fiscal year 2025 has been updated. 2025 revenue forecast increased from US$3.31m to US$4.85m. EPS estimate fell from -US$9.55 to -US$10.14 per share. Biotechs industry in the US expected to see average net income decline 12% next year. Consensus price target broadly unchanged at US$99.23. Share price rose 20% to US$19.14 over the past week.分析記事 • Jul 05We're Keeping An Eye On Korro Bio's (NASDAQ:KRRO) Cash Burn RateWe can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...お知らせ • Jun 30+ 5 more updatesKorro Bio, Inc.(NasdaqCM:KRRO) dropped from Russell 3000E Growth IndexKorro Bio, Inc.(NasdaqCM:KRRO) dropped from Russell 3000E Growth IndexNew Risk • Jun 06New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 17% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (17% average weekly change). Earnings are forecast to decline by an average of 9.1% per year for the foreseeable future. Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$146m net loss in 3 years). Revenue is less than US$5m (US$4.8m revenue).Price Target Changed • May 16Price target decreased by 13% to US$102Down from US$117, the current price target is an average from 10 analysts. New target price is 574% above last closing price of US$15.11. Stock is down 72% over the past year. The company is forecast to post a net loss per share of US$9.55 next year compared to a net loss per share of US$9.37 last year.Major Estimate Revision • May 14Consensus revenue estimates increase by 137%The consensus outlook for revenues in fiscal year 2025 has improved. 2025 revenue forecast increased from US$1.35m to US$3.20m. Forecast losses expected to reduce from -US$10.23 to -US$9.51 per share. Biotechs industry in the US expected to see average net income decline 13% next year. Consensus price target down from US$117 to US$102. Share price was steady at US$14.11 over the past week.お知らせ • Apr 30Korro Bio, Inc., Annual General Meeting, Jun 11, 2025Korro Bio, Inc., Annual General Meeting, Jun 11, 2025.Price Target Changed • Apr 29Price target decreased by 7.3% to US$117Down from US$126, the current price target is an average from 10 analysts. New target price is 601% above last closing price of US$16.67. Stock is down 71% over the past year. The company is forecast to post a net loss per share of US$10.23 next year compared to a net loss per share of US$9.37 last year.Major Estimate Revision • Apr 24Consensus revenue estimates increase by 156%The consensus outlook for fiscal year 2025 has been updated. 2025 revenue forecast increased from US$250.0k to US$640.0k. EPS estimate unchanged from -US$10.40 at last update. Biotechs industry in the US expected to see average net income decline 13% next year. Consensus price target down from US$139 to US$122. Share price rose 25% to US$17.44 over the past week.Price Target Changed • Apr 17Price target decreased by 9.9% to US$126Down from US$140, the current price target is an average from 9 analysts. New target price is 807% above last closing price of US$13.90. Stock is down 79% over the past year. The company is forecast to post a net loss per share of US$10.40 next year compared to a net loss per share of US$9.37 last year.お知らせ • Apr 01Korro Bio, Inc. Appoints Loïc Vincent as Chief Scientific OfficerKorro Bio, Inc. announced the appointment of Loïc Vincent as Chief Scientific Officer. Dr. Vincent joins Korro with more than 20 years in drug discovery and translational research across academia, biotech and the pharmaceutical industry. Throughout his career, Dr. Vincent led teams that advanced more than 20 drugs into clinical development based on various therapeutic modalities including small molecules, biologics, viral platforms and cell therapies. Prior to joining Korro, Dr. Vincent served as Chief Scientific Officer at Affini-T Therapeutics leading efforts to advance next-generation therapies. Previously, he was Head of the Oncology Drug Discovery Unit and Immunology Unit at Takeda. Before that, Dr. Vincent led Oncology Drug Discovery Pharmacology, Immunotherapy and Oncology External Innovation teams at Sanofi, and earlier in his career, he headed Pharmacology and Oncology programs at Endotis Pharma. Dr. Vincent currently serves on the Scientific Advisory Boards of bit.bio and General Inception, and is a Director on the Board of Alaya.bio. Dr. Vincent obtained his Ph.D. in pharmacology from the University of Rouen, France, and completed his postdoctoral fellowship in oncology at the Weill Medical College of Cornell University, New York.分析記事 • Mar 19Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?We can readily understand why investors are attracted to unprofitable companies. For example, although...お知らせ • Feb 13Korro Bio, Inc. Appoints Oliver Dolan as Interim Principal Accounting OfficerEffective February 11, 2025, Vineet Agarwal, Chief Financial Officer (principal financial officer and principal accounting officer) of Korro Bio, Inc., is taking a temporary medical leave of absence. Accordingly, effective from February 11, 2025, Korro’s Board of Directors appointed Mr. Oliver Dolan, Senior Vice President, Finance, to serve as Korro’s interim principal accounting officer, in each case, in addition to their current duties. Mr. Dolan, age 42, has served as Korro’s Senior Vice President of Finance since January 2024. Prior to joining Korro, Mr. Dolan served as Vice President, Accounting, Tax and Treasury at Unity Biotechnology from December 2020 to December 2023. Prior to that, Mr. Dolan served as Head of Finance at Haven Healthcare from May 2020 to December 2020. Prior to that, Mr. Dolan served as Vice President of Finance at Compass Therapeutics from October 2018 to May 2020. Mr. Dolan holds an MBA from MIT Sloan School of Management, a Bachelor of Commerce degree from the University College Dublin and he is licensed as a Certified Public Accountant.お知らせ • Jan 13Korro Bio Announces Dosing of First Participants in REWRITE Phase 1/2a Study of KRRO-110 for Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. announced the initiation of dosing in its REWRITE study investigating KRRO-110 as a potential treatment for individuals with Alpha-1 Antitrypsin Deficiency (AATD). REWRITE is a two-part single and multiple dose-escalating study that will evaluate the safety and tolerability of KRRO-110 in up to 64 participants, including healthy adults and clinically stable AATD patients with the PiZZ genotype. Secondary and exploratory endpoints include pharmacokinetic and pharmacodynamic parameters that will guide optimal dose selection for later stage studies. Interim data from Part 1 (single ascending doses in healthy volunteers and individuals with AATD) is expected in the second half of 2025, and completion of the study is anticipated in 2026. For additional information about the REWRITE study, visit ClinicalTrials.gov (NCT06677307). In addition to advancing KRRO-110, Korro is progressing a pipeline of wholly owned programs and a Novo Nordisk partnered program in a cardiometabolic indication towards the clinic.お知らせ • Dec 03Korro Bio, Inc. has filed a Follow-on Equity Offering in the amount of $100 million.Korro Bio, Inc. has filed a Follow-on Equity Offering in the amount of $100 million. Security Name: Common Stock Security Type: Common Stock Transaction Features: At the Market Offering分析記事 • Nov 28We Think Korro Bio (NASDAQ:KRRO) Needs To Drive Business Growth CarefullyJust because a business does not make any money, does not mean that the stock will go down. For example, although...Recent Insider Transactions Derivative • Nov 17Chief Financial Officer notifies of intention to sell stockVineet Agarwal intends to sell 800 shares in the next 90 days after lodging an Intent To Sell Form on the 11th of November. If the sale is conducted around the recent share price of US$70.00, it would amount to US$56k. Since December 2023, Vineet has not owned shares directly (This sale likely refers to shares that have not yet been received). Company insiders have collectively sold US$767k more than they bought, via options and on-market transactions in the last 12 months.お知らせ • Nov 05+ 1 more updateKorro Bio, Inc. Announces Submission to Bellberry HREC for Phase 1/2 Clinical Study of KRRO-110 for AATDKorro Bio, Inc. announced a submission to the Bellberry HREC for a Phase 1/2 clinical study of KRRO-110 for AATD. A Clinical Advisory Board (CAB) comprised of distinguished lung and liver researchers and experts in AATD has also been assembled to help guide the clinical development strategy for KRRO-110. Subject to approval by the HREC and acceptance of the clinical trial notification (CTN) by Australia’s Therapeutic Goods Administration (TGA), Korro anticipates dosing the first participant in the Phase 1/2 study in the first quarter of 2025. An interim data readout for the Phase 1/2 study of KRRO-110 is anticipated in the second half of 2025, and completion of the study is expected in 2026.Recent Insider Transactions Derivative • Oct 20Chief Financial Officer notifies of intention to sell stockVineet Agarwal intends to sell 10k shares in the next 90 days after lodging an Intent To Sell Form on the 17th of October. If the sale is conducted around the recent share price of US$78.26, it would amount to US$800k. Since December 2023, Vineet has not owned shares directly (This sale likely refers to shares that have not yet been received). Company insiders have collectively sold US$761k more than they bought, via options and on-market transactions in the last 12 months.お知らせ • Aug 28Korro Bio, Inc. Announces Board ChangesKorro Bio, Inc. announced that the Board of Directors has appointed Katharine Knobil, M.D. as an Independent Director, effective immediately. Korro also announced that David Lucchino has stepped down from the Board. Dr. Knobil brings a wealth of experience in clinical development and regulatory affairs to Korro. With over 25 years in the pharmaceutical and biotech industries, she has played a pivotal role in advancing numerous therapeutics from early-stage development to regulatory approval and commercialization. She most recently served as Chief Medical Officer at Agilent Technologies, where she established an industry-leading medical affairs organization and was responsible for integrating the voice of patients into business and clinical development strategy and decision-making. Previously, she was Chief Medical Officer and Head of Research and Development at Kaleido Biosciences. Before that, Dr. Knobil spent more than 20 years at GlaxoSmithKline (GSK) in roles of increasing responsibility, most recently serving as Chief Medical Officer. Dr. Knobil is currently a member of the Board of Directors at Nimbus Therapeutics, Marker Therapeutics and Pliant Therapeutics. Dr. Knobil is a recognized leader in the field, having authored numerous publications and presented at major industry conferences. She received an M.D. from the University of Texas Southwestern Medical School and completed her subsequent fellowship in Pulmonary Medicine and Critical Care Medicine at Johns Hopkins University.分析記事 • Aug 15We Think Korro Bio (NASDAQ:KRRO) Needs To Drive Business Growth CarefullyWe can readily understand why investors are attracted to unprofitable companies. For example, although...Board Change • May 17High number of new and inexperienced directorsThere are 6 new directors who have joined the board in the last 3 years. The company's board is composed of: 6 new directors. No experienced directors. 1 highly experienced director. Director David Lucchino is the most experienced director on the board, commencing their role in 2014. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.お知らせ • May 16Korro Bio, Inc. Announces the Appointment of Kemi Olugemo, M.D. as Chief Medical OfficerKorro Bio, Inc. announced the appointment of Dr. Kemi Olugemo as Chief Medical Officer. Dr. Olugemo brings more than 10 years of industry experience focused on clinical development and regulatory strategy. She joins Korro after serving as VP & Therapeutic Head, Neurology Global Clinical Development at Ultragenyx Pharmaceutical. In this role, she directed and oversaw the overall strategy for clinical drug product development, supported the development of global regulatory plans, and identified critical opportunities for external collaborations. Dr. Olugemo holds an M.D. from the University of Maryland School of Medicine and a B.Sc. in Clinical Laboratory Science from the University of Massachusetts, Lowell. With her experience in rare and more prevalent diseases, Dr. Olugemo will provide invaluable expertise and leadership to advance Korro’s clinical and regulatory initiatives.お知らせ • May 01Korro Bio, Inc., Annual General Meeting, Jun 11, 2024Korro Bio, Inc., Annual General Meeting, Jun 11, 2024, at 13:30 US Eastern Standard Time. Agenda: To consider Election of two Class II directors, Ali Behbahani and Timothy Pearson, nominated by board of directors, each to serve for a three-year term expiring at the 2027 annual meeting of stockholders; to consider Approval of an amendment to Restated Certificate of Incorporation to limit the liability of certain officers as permitted by amendments to Delaware law; to consider Ratification of the appointment of Ernst & Young LLP as independent registered public accounting firm for the fiscal year ending December 31, 2024; and to consider other matters.お知らせ • Apr 23Korro Bio, Inc. announced that it has received $69.959848 million in funding from Atlas Venture L.P., Deep Track Capital, LP, Blue Owl Healthcare Opportunities, Rock Springs Capital Management LP, Tri Locum Partners LP, New Enterprise Associates, Inc.On April 22, 2024, Korro Bio, Inc. closed the transaction.お知らせ • Apr 19Korro Bio, Inc. announced that it expects to receive $69.959848 million in funding from Atlas Venture L.P., Deep Track Capital, LP, Blue Owl Healthcare Opportunities, Rock Springs Capital Management LP, Tri Locum Partners LP, New Enterprise Associates, Inc.Korro Bio, Inc. announces it has entered into a subscription agreement with a number of institutional accredited investors to issue 1,249,283 shares of common stock at a issue price of $56 per share for gross proceeds of $69,959,848 on April 17, 2024. The transaction will include participation from Deep Track Capital, as lead investor and Atlas Venture, Blue Owl Healthcare Opportunities, NEA, Rock Springs Capital, Tri Locum Partners, and other leading healthcare investors. The transaction is expected to close on April 22, 2024.分析記事 • Mar 30We Think Korro Bio (NASDAQ:KRRO) Can Afford To Drive Business GrowthWe can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...New Risk • Dec 08New minor risk - Financial data availabilityLess than 3 years of financial data is available. This is considered a minor risk. If the company has been trading for less than 3 years, then it has not had the opportunity to establish a long-term track record. This makes it difficult for investors to assess the true growth potential, sustainability and resilience of the business under different economic conditions. Currently, the following risks have been identified for the company: Major Risks Shares are highly illiquid. Earnings are forecast to decline by an average of 8.4% per year for the foreseeable future. Revenue is less than US$1m. Minor Risks Less than 3 years of financial data is available. Currently unprofitable and not forecast to become profitable over next 3 years (US$93m net loss in 3 years). Significant insider selling over the past 3 months (US$84k sold).お知らせ • Dec 07Korro Announces Selection of Its First Development Candidate for the Potential Treatment of Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. has nominated its first development candidate, KRRO-110, for the potential treatment of AATD. KRRO-110 is a proprietary RNA editing oligonucleotide delivered to liver cells using clinically validated LNP technology licensed from Genevant. KRRO-110 is designed to co-opt an endogenous enzyme Adenosine Deaminase Acting on RNA (ADAR) to repair a pathogenic single nucleotide variant (SNV) on RNA and restore production of normal A1AT. AATD is an inherited genetic disorder caused by SNVs in the SERPINA1 gene that can lead to severe progressive lung disease, including emphysema and chronic obstructive pulmonary disease (COPD), and liver disease. There are an estimated 3.4 million individuals with deficiency allele combinations worldwide. The only current FDA-approved treatment for AATD is augmentation therapy, a once-weekly infusion of pooled human plasma-derived A1AT protein, which does not adequately address the manifestations of AATD.お知らせ • Nov 30Korro Bio, Inc. Appoints Rachel Meyers as Board of Directors, Member of Nominating and Corporate Governance CommitteeKorro Bio, Inc. announced the appointment of Rachel Meyers, PhD, to the company’s board of directors. Dr. Meyers is a seasoned biotechnology veteran whose experience in life sciences spans over two decades. Most recently, Dr. Meyers served as Chief Scientific Officer of Faze Medicines. Previously, she was an Entrepreneur-in-Residence at Third Rock Ventures. Before that, Dr. Meyers held multiple leadership positions at Alnylam Pharmaceuticals for over 13 years, most recently as Senior Vice President of Research and RNAi Lead Development. Rachel completed her post-doctoral training at Harvard University and holds a PhD in Biology from the Massachusetts Institute of Technology and a BA in Biochemistry from Brandeis University. Dr. Meyers was also appointed by the Board upon the recommendation of the NCG Committee to serve as a member of the Nominating and Corporate Governance Committee or NCG Committee.Board Change • Nov 07No independent directorsFollowing the recent departure of a director, there are no independent directors on the board. The company's board is composed of: No independent directors. 7 non-independent directors. Director Omar Khwaja was the last director to join the board, commencing their role in 2020. The company's lack of independent directors is a risk according to the Simply Wall St Risk Model.お知らせ • Nov 07Frequency Therapeutics, Inc. announced that it has received $117.249989 million in funding from a group of investorsOn November 6, 2023, Frequency Therapeutics, Inc. closed the transaction. The company issued 42,176,255 common shares at a price of $2.78 per share for gross proceeds of $117.249989 million.株主還元KRROUS BiotechsUS 市場7D-0.9%3.7%1.6%1Y4.3%37.9%21.1%株主還元を見る業界別リターン: KRRO過去 1 年間で37.9 % の収益を上げたUS Biotechs業界を下回りました。リターン対市場: KRROは、過去 1 年間で21.1 % のリターンを上げたUS市場を下回りました。価格変動Is KRRO's price volatile compared to industry and market?KRRO volatilityKRRO Average Weekly Movement13.1%Biotechs Industry Average Movement10.3%Market Average Movement7.2%10% most volatile stocks in US Market16.7%10% least volatile stocks in US Market3.1%安定した株価: KRROの株価は、 US市場と比較して過去 3 か月間で変動しています。時間の経過による変動: KRROの weekly volatility ( 13% ) は過去 1 年間安定していますが、依然としてUSの株式の 75% よりも高くなっています。会社概要設立従業員CEO（最高経営責任者ウェブサイト201849Ram Aiyarwww.korrobio.comコーロ・バイオ社はバイオ医薬品会社で、米国において希少疾患や高度に蔓延している疾患の治療のため、RNA編集に基づく遺伝子医薬品の発見、開発、商業化に従事している。同社の主要製品候補は高アンモニア血症治療薬のKRRO-121である。同社は、RNA編集プラットフォームであるオリゴヌクレオチドによるRNA編集を促進し、差別化されたRNA編集製品候補を生み出している。同社はまた、パーキンソン病、筋萎縮性側索硬化症、重篤な薬物関連麻酔薬、その他の疼痛を適応症とするプログラムも開発している。コーロ・バイオ社はノボ・ノルディスク社（Novo Nordisk A/S）と心代謝性疾患の治療に関する共同研究契約を結んでいる。Korro Bio, Inc.は2018年に設立され、マサチューセッツ州ケンブリッジに本社を置いている。もっと見るKorro Bio, Inc. 基礎のまとめKorro Bio の収益と売上を時価総額と比較するとどうか。KRRO 基礎統計学時価総額US$196.87m収益（TTM）-US$113.50m売上高(TTM)US$3.84m51.2xP/Sレシオ-1.7xPER（株価収益率KRRO は割高か？公正価値と評価分析を参照収益と収入最新の決算報告書（TTM）に基づく主な収益性統計KRRO 損益計算書（TTM）収益US$3.84m売上原価US$48.17m売上総利益-US$44.33mその他の費用US$69.17m収益-US$113.50m直近の収益報告Mar 31, 2026次回決算日該当なし一株当たり利益（EPS）-7.87グロス・マージン-1,153.88%純利益率-2,954.14%有利子負債／自己資本比率0%KRRO の長期的なパフォーマンスは？過去の実績と比較を見るView Valuation企業分析と財務データの現状データ最終更新日（UTC時間）企業分析2026/07/01 15:23終値2026/07/01 00:00収益2026/03/31年間収益2025/12/31データソース企業分析に使用したデータはS&P Global Market Intelligence LLC のものです。本レポートを作成するための分析モデルでは、以下のデータを使用しています。データは正規化されているため、ソースが利用可能になるまでに時間がかかる場合があります。パッケージデータタイムフレーム米国ソース例会社財務10年損益計算書キャッシュ・フロー計算書貸借対照表SECフォーム10-KSECフォーム10-Qアナリストのコンセンサス予想+プラス3年予想財務アナリストの目標株価アナリストリサーチレポートBlue Matrix市場価格30年株価配当、分割、措置ICEマーケットデータSECフォームS-1所有権10年トップ株主インサイダー取引SECフォーム4SECフォーム13Dマネジメント10年リーダーシップ・チーム取締役会SECフォーム10-KSECフォームDEF 14A主な進展10年会社からのお知らせSECフォーム8-K* 米国証券を対象とした例であり、非米国証券については、同等の規制書式および情報源を使用。特に断りのない限り、すべての財務データは1年ごとの期間に基づいていますが、四半期ごとに更新されます。これは、TTM（Trailing Twelve Month）またはLTM（Last Twelve Month）データとして知られています。詳細はこちら。分析モデルとスノーフレークこのレポートを生成するために使用した分析モデルの詳細は、当社の Github ページ でご覧いただけます。また、レポートの使い方に関する ガイド や YouTube の チュートリアル もご用意しています。シンプリー・ウォールストリート分析モデルを設計・構築した世界トップクラスのチームについてご紹介します。業界およびセクターの指標私たちの業界とセクションの指標は、Simply Wall Stによって6時間ごとに計算されます。アナリスト筋Korro Bio, Inc. 10 これらのアナリストのうち、弊社レポートのインプットとして使用した売上高または利益の予想を提出したのは、 。アナリストの投稿は一日中更新されます。15 アナリスト機関Steven SeedhouseCantor Fitzgerald & Co.Tu Cam NguyenCGS InternationalKeay NakaeChardan Capital Markets, LLC12 その他のアナリストを表示
Recent Insider Transactions • Jun 18Senior VP recently sold US$72k worth of stockOn the 16th of June, Jeffrey Cerio sold around 7k shares on-market at roughly US$10.83 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. In the last 3 months, there was an even bigger sale from another insider worth US$197k. Insiders have been net sellers, collectively disposing of US$376k more than they bought in the last 12 months.
Recent Insider Transactions Derivative • Jun 17Senior VP notifies of intention to sell stockJeffrey Cerio intends to sell 7k shares in the next 90 days after lodging an Intent To Sell Form on the 16th of June. If the sale is conducted around the recent share price of US$10.83, it would amount to US$72k. As of today, Jeffrey currently holds no shares directly (This sale likely refers to shares that have not yet been received). There has only been one transaction (US$197k sale) from insiders over the last 12 months.
分析記事 • Jun 16Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Seeking Alpha • Jun 15Korro Bio: RNA Editor Plots Way Back After AATD Study Fail - I'm HoldingSummary Korro Bio faces high uncertainty after KRRO-110 failed to meet clinical expectations in AATD, prompting a pipeline overhaul. KRRO-121, targeting hyperammonemia, and KRRO-111, a next-gen AATD candidate, show promising preclinical data but lack clinical proof-of-concept. KRRO's $157.1M cash position funds operations into 2H 2028, but late-stage trials will require additional capital if early data are positive. I am holding KRRO for potential upside but advise caution until Phase 1/2 data derisk the platform; risk/reward is high given competition and unproven clinical efficacy. Read the full article on Seeking Alpha
New Risk • Jun 10New minor risk - Insider sellingThere has been significant insider selling in the company's shares over the past 3 months. Total value of shares sold: US$197k This is considered a minor risk. There are several reasons why an insider may be selling, including to cover a tax obligation or pay for some other expense. However, we generally consider it a negative if insiders have been selling, especially if they do so below the current price. It implies that they considered a lower price to be reasonable. This is a weak signal, but if there is a pattern of unexplained selling, it can be a sign the insider believes the company's stock is overpriced. Note: We only include open market transactions and private dispositions of directly owned stock by individuals, not by corporations or trusts. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 12% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (54% increase in shares outstanding). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$123m net loss in 3 years). Share price has been volatile over the past 3 months (12% average weekly change). Significant insider selling over the past 3 months (US$197k sold). Revenue is less than US$5m (US$3.8m revenue).
Recent Insider Transactions • Jun 02CEO, President recently sold US$197k worth of stockOn the 29th of May, Ram Aiyar sold around 15k shares on-market at roughly US$12.98 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. This was the largest sale by an insider in the last 3 months. This was Ram's only on-market trade for the last 12 months.
Recent Insider Transactions • Jun 18Senior VP recently sold US$72k worth of stockOn the 16th of June, Jeffrey Cerio sold around 7k shares on-market at roughly US$10.83 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. In the last 3 months, there was an even bigger sale from another insider worth US$197k. Insiders have been net sellers, collectively disposing of US$376k more than they bought in the last 12 months.
Recent Insider Transactions Derivative • Jun 17Senior VP notifies of intention to sell stockJeffrey Cerio intends to sell 7k shares in the next 90 days after lodging an Intent To Sell Form on the 16th of June. If the sale is conducted around the recent share price of US$10.83, it would amount to US$72k. As of today, Jeffrey currently holds no shares directly (This sale likely refers to shares that have not yet been received). There has only been one transaction (US$197k sale) from insiders over the last 12 months.
分析記事 • Jun 16Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Seeking Alpha • Jun 15Korro Bio: RNA Editor Plots Way Back After AATD Study Fail - I'm HoldingSummary Korro Bio faces high uncertainty after KRRO-110 failed to meet clinical expectations in AATD, prompting a pipeline overhaul. KRRO-121, targeting hyperammonemia, and KRRO-111, a next-gen AATD candidate, show promising preclinical data but lack clinical proof-of-concept. KRRO's $157.1M cash position funds operations into 2H 2028, but late-stage trials will require additional capital if early data are positive. I am holding KRRO for potential upside but advise caution until Phase 1/2 data derisk the platform; risk/reward is high given competition and unproven clinical efficacy. Read the full article on Seeking Alpha
New Risk • Jun 10New minor risk - Insider sellingThere has been significant insider selling in the company's shares over the past 3 months. Total value of shares sold: US$197k This is considered a minor risk. There are several reasons why an insider may be selling, including to cover a tax obligation or pay for some other expense. However, we generally consider it a negative if insiders have been selling, especially if they do so below the current price. It implies that they considered a lower price to be reasonable. This is a weak signal, but if there is a pattern of unexplained selling, it can be a sign the insider believes the company's stock is overpriced. Note: We only include open market transactions and private dispositions of directly owned stock by individuals, not by corporations or trusts. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 12% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (54% increase in shares outstanding). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$123m net loss in 3 years). Share price has been volatile over the past 3 months (12% average weekly change). Significant insider selling over the past 3 months (US$197k sold). Revenue is less than US$5m (US$3.8m revenue).
Recent Insider Transactions • Jun 02CEO, President recently sold US$197k worth of stockOn the 29th of May, Ram Aiyar sold around 15k shares on-market at roughly US$12.98 per share. This transaction amounted to 16% of their direct individual holding at the time of the trade. This was the largest sale by an insider in the last 3 months. This was Ram's only on-market trade for the last 12 months.
Recent Insider Transactions Derivative • May 31CEO, President notifies of intention to sell stockRam Aiyar intends to sell 15k shares in the next 90 days after lodging an Intent To Sell Form on the 29th of May. If the sale is conducted around the recent share price of US$12.98, it would amount to US$197k. For the year to December 2022, Ram's total compensation was 20% salary and 80% other compensation. This indicates that these sales could comprise a meaningful part of their income for the year. Since March 2026, Ram has owned 4.61k shares directly. There have been no trades via on-market transactions or options from company insiders in the last 12 months.
Major Estimate Revision • May 21Consensus revenue estimates increase by 11%, EPS downgradedThe consensus outlook for fiscal year 2026 has been updated. 2026 revenue forecast increased from US$500.0k to US$560.0k. EPS estimate fell from -US$5.27 to -US$5.45 per share. Biotechs industry in the US expected to see average net income decline 9.8% next year. Consensus price target down from US$20.38 to US$19.89. Share price was steady at US$11.20 over the past week.
お知らせ • May 20Korro Bio, Inc. Selects Krro-111 As Development Candidate For The Potential Treatment Of Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. announced the addition of KRRO-111 for the potential treatment of AATD to its pipeline of therapeutic programs in development. KRRO-111 is a proprietary GalNAc-conjugated oligonucleotide that is delivered subcutaneously to the liver cells, where it is engineered to co-opt the hepatocytes’ endogenous Adenosine Deaminase Acting on RNA (ADAR) enzyme and repair a pathogenic single nucleotide variant (SNV) on AAT mRNA to restore production of normal AAT protein. This therapeutic profile along with KRRO-111’s rapid onset of action and titratable dosing to treat this disorder, position the compound as a potential best-in-class candidate. AATD is a genetic disorder most commonly caused by a single missense mutation (G-to-A) in the SERPINA1 gene. Affected adults experience pulmonary emphysema and/or hepatic cirrhosis, as well as end organ manifestations. Greater than 95% of severe clinical cases of AATD are homozygous for the PiZ mutation (known as the PiZZ genotype). There are an estimated 3,400,000 individuals with deficiency allele combinations worldwide. The only current FDA-approved treatment for AATD is augmentation therapy, a once-weekly infusion of pooled human plasma-derived AAT protein, which does not adequately address the manifestations of AATD. In preclinical studies, KRRO-111 demonstrated best-in-class RNA editing where >90% of the AAT transcripts in the liver cells have been corrected, translating into ~90% M-AAT protein. In a repeat-dose study, KRRO-111 (3 mg/kg) was administered to PiZZ mice with a loading phase followed by dosing once every two weeks. KRRO-111 nearly eliminated active Z protein production, reducing non-inclusion Z-AAT by ~95% versus vehicle at both days 28 and 56, reflecting near-complete cessation of Z protein synthesis across the hepatocyte population. Pre-existing aggregates were progressively cleared, with inclusion-associated Z-AAT significantly reduced by approximately 69% at day 28, consistent with autophagic clearance of accumulated protein following successful editing; the residual burden reflects pre-existing disease rather than incomplete editing. By simultaneously increasing circulating M-AAT protein and decreasing pathogenic Z-AAT aggregates in the lung, KRRO-111 has the potential to improve both lung and liver manifestations of the disease. The Company plans to present additional data from its KRRO-111 program at a future scientific meeting or Company-hosted event.
Major Estimate Revision • May 14Consensus EPS estimates upgraded to US$5.27 lossThe consensus outlook for fiscal year 2026 has been updated. 2026 losses forecast to reduce from -US$6.75 to -US$5.27 per share. Revenue forecast unchanged from US$500.0k at last update. Biotechs industry in the US expected to see average net income decline 9.8% next year. Consensus price target of US$20.38 unchanged from last update. Share price fell 16% to US$11.20 over the past week.
Reported Earnings • May 07First quarter 2026 earnings released: US$1.69 loss per share (vs US$2.49 loss in 1Q 2025)First quarter 2026 results: US$1.69 loss per share (improved from US$2.49 loss in 1Q 2025). Net loss: US$19.6m (loss narrowed 16% from 1Q 2025). Revenue is forecast to grow 60% p.a. on average during the next 3 years, compared to a 21% growth forecast for the Biotechs industry in the US.
お知らせ • Apr 17Korro Bio, Inc., Annual General Meeting, Jun 10, 2026Korro Bio, Inc., Annual General Meeting, Jun 10, 2026.
Major Estimate Revision • Mar 19Consensus revenue estimates increase by 52,586%The consensus outlook for revenues in fiscal year 2026 has improved. 2026 revenue forecast increased from US$1.27m to US$667.4m. Forecast losses expected to reduce from -US$8.27 to -US$6.75 per share. Biotechs industry in the US expected to see average net income decline 12% next year. Consensus price target up from US$19.33 to US$20.00. Share price fell 3.8% to US$11.06 over the past week.
New Risk • Mar 13New major risk - Shareholder dilutionThe company's shareholders have been substantially diluted in the past year. Increase in shares outstanding: 54% This is considered a major risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Major Risks Earnings are forecast to decline by an average of 9.8% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (54% increase in shares outstanding). Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$108m net loss in 3 years).
お知らせ • Mar 09Korro Bio, Inc. announced that it expects to receive $84.996839 million in funding from a group of investorsKorro Bio, Inc announced a private placement and entered into a subscription agreement to issue 4,501,928 common shares at price of $11.11 per share for aggregate proceeds of $50,016,420.08 and 3,148,836 pre-funded warrants at a price of $11.109 for aggregate proceeds of $34,980,419.124, total gross proceeds amounting to $84,996,839.204 on March 9. 2026. The transaction included participation from lead Investor Venrock Healthcare Capital Partners, ADAR1 Capital Management, Affinity Asset Advisors, Balyasny Asset Management, Driehaus Capital Management, Kalehua Capital, Lynx1 Capital Management, Nantahala Capital, and New Enterprise Associates. The pre-funded warrants have an exercise price of $0.001 per underlying share of common stock, are immediately exercisable and have no expiration date. The transaction is expected to close on March 10, 2026 subject to customary closing conditions. The securities will be issued in reliance upon the exemption from securities registration afforded by Section 4(a)(2) of the 1933 Act and not in reliance upon any of the safe harbors set forth in Regulation D promulgated thereunder.
Price Target Changed • Feb 12Price target increased by 123% to US$19.33Up from US$8.67, the current price target is an average from 6 analysts. New target price is 64% above last closing price of US$11.76. Stock is down 60% over the past year. The company is forecast to post a net loss per share of US$9.05 next year compared to a net loss per share of US$9.37 last year.
Board Change • Feb 12High number of new and inexperienced directorsThere are 12 new directors who have joined the board in the last 3 years. The company's board is composed of: 12 new directors. No experienced directors. No highly experienced directors. Independent Director Ali Behbahani is the most experienced director on the board, commencing their role in 2023. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.
お知らせ • Nov 13+ 2 more updatesKorro Bio, Inc. Provides Updates on KRRO-110 in Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. provided a program update for its Phase 1/2a REWRITE clinical trial of KRRO-110 in AATD. The REWRITE Phase 1/2a clinical trial is a two-part single and multiple-dose escalating study evaluating the safety and tolerability of KRRO-110, including healthy adults and clinically stable AATD patients with the PiZZ genotype. Korro has completed all six planned single ascending dose (SAD) healthy volunteer (HV) cohorts. Each HV cohort consisted of six participants, with four receiving active drug and two receiving placebo. Doses of KRRO-110 tested in the HVs (n=24) include 0.04, 0.1, 0.2, 0.4, 0.8 and 1.2 mg/kg, with the primary objective to evaluate safety and tolerability. KRRO-110 is currently being evaluated in two AATD patient cohorts at 0.6 mg/kg (n=3) and 0.8 mg/kg (n=4), with seven patients dosed. The AATD patient cohorts are open label with up to four patients in each cohort. There are currently no plans to complete additional SAD patient cohorts for KRRO-110. Korro is evaluating the totality of the clinical data to evaluate the next steps, if any, for KRRO-110 in the multiple-ascending dose (MAD) portion of the REWRITE clinical trial. KRRO-110 Safety Observations (as of the November 6, 2025 Data Cutoff Date): No dose-limiting toxicities or treatment emergent serious adverse events observed. Mild-to-moderate infusion-related reactions (IRRs) observed in two healthy volunteers at the highest dose of 1.2 mg/kg, two AATD patients at 0.6 mg/kg, and two AATD patients at 0.8 mg/kg. All IRRs resolved within 24 hours post KRRO-110 dosing; intervention was limited to antipyretics and antihistamines. KRRO-110 safety profile is consistent with Lipid Nanoparticles (LNP) infusion-related class effects. KRRO-110 Pharmacodynamic and Pharmacokinetic Observations (as of the November 6, 2025 Data Cutoff Date): Across five AATD patients in the two SAD cohorts evaluable with turbidimetry, the greatest peak total AAT protein was approximately 10 µM and the greatest increase of total AAT protein from baseline was approximately 3 µM. The total AAT protein levels following single-dose administration did not reach the protective threshold of 11 µM. In three of the AATD patients dosed with 0.8 mg/kg evaluable with LC/MS, functional M-AAT protein was observed in each of the patients following administration of KRRO-110. The greatest increase of M-AAT protein from baseline observed at any time point was approximately 2 µM. Functional M-AAT protein lasted up to four weeks for the first patient evaluable with LC/MS, consistent with durability of editing and endogenous M-AAT protein half-life. Pharmacokinetic differences in the components of KRRO-110 in plasma were observed between HV and AATD patients, with apparent faster disassociation of KRRO-110, suggesting variability of this formulation in AATD patients compared to HV following a single dose. No evidence of bystander editing observed to date, suggesting high specificity, based on LC/MS data on M-AAT and Z-AAT. KRRO-110 Regulatory Milestones Validate OPERA Platform Potential: First-ever RNA editing technology to receive Investigational New Drug clearance by the U.S. Food and Drug Administration (FDA) to Korro’s knowledge. Fast Track designation granted by the FDA. Orphan Drug Designation granted by both the FDA and European Medicines Agency.
分析記事 • Oct 23Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
お知らせ • Oct 08Korro Bio, Inc. Announces Chief Financial Officer Changes, Effective October 17, 2025On October 7, 2025, Vineet Agarwal announced his intention to resign from his position of Chief Financial Officer of Korro Bio, Inc., or Korro, effective October 17, 2025 to pursue another opportunity. In order to ensure the smooth transition of his functions, Mr. Agarwal has agreed to be available to serve as an advisor for 30 days thereafter. The board of directors of Korro, or the Board, and Korro are incredibly thankful to Mr. Agarwal for his long-standing service at Korro. In light of Mr. Agarwal’s resignation, the Board appointed Dr. Ram Aiyar, President and Chief Executive Officer (principal executive officer), to serve as Korro’s interim Chief Financial Officer and principal financial officer, in addition to his current duties effective from October 17, 2025.
Price Target Changed • Sep 10Price target decreased by 8.4% to US$92.33Down from US$101, the current price target is an average from 9 analysts. New target price is 156% above last closing price of US$36.12. Stock is down 7.0% over the past year. The company is forecast to post a net loss per share of US$10.14 next year compared to a net loss per share of US$9.37 last year.
Major Estimate Revision • Aug 19Consensus revenue estimates increase by 47%, EPS downgradedThe consensus outlook for fiscal year 2025 has been updated. 2025 revenue forecast increased from US$3.31m to US$4.85m. EPS estimate fell from -US$9.55 to -US$10.14 per share. Biotechs industry in the US expected to see average net income decline 12% next year. Consensus price target broadly unchanged at US$99.23. Share price rose 20% to US$19.14 over the past week.
分析記事 • Jul 05We're Keeping An Eye On Korro Bio's (NASDAQ:KRRO) Cash Burn RateWe can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
お知らせ • Jun 30+ 5 more updatesKorro Bio, Inc.(NasdaqCM:KRRO) dropped from Russell 3000E Growth IndexKorro Bio, Inc.(NasdaqCM:KRRO) dropped from Russell 3000E Growth Index
New Risk • Jun 06New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 17% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (17% average weekly change). Earnings are forecast to decline by an average of 9.1% per year for the foreseeable future. Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$146m net loss in 3 years). Revenue is less than US$5m (US$4.8m revenue).
Price Target Changed • May 16Price target decreased by 13% to US$102Down from US$117, the current price target is an average from 10 analysts. New target price is 574% above last closing price of US$15.11. Stock is down 72% over the past year. The company is forecast to post a net loss per share of US$9.55 next year compared to a net loss per share of US$9.37 last year.
Major Estimate Revision • May 14Consensus revenue estimates increase by 137%The consensus outlook for revenues in fiscal year 2025 has improved. 2025 revenue forecast increased from US$1.35m to US$3.20m. Forecast losses expected to reduce from -US$10.23 to -US$9.51 per share. Biotechs industry in the US expected to see average net income decline 13% next year. Consensus price target down from US$117 to US$102. Share price was steady at US$14.11 over the past week.
お知らせ • Apr 30Korro Bio, Inc., Annual General Meeting, Jun 11, 2025Korro Bio, Inc., Annual General Meeting, Jun 11, 2025.
Price Target Changed • Apr 29Price target decreased by 7.3% to US$117Down from US$126, the current price target is an average from 10 analysts. New target price is 601% above last closing price of US$16.67. Stock is down 71% over the past year. The company is forecast to post a net loss per share of US$10.23 next year compared to a net loss per share of US$9.37 last year.
Major Estimate Revision • Apr 24Consensus revenue estimates increase by 156%The consensus outlook for fiscal year 2025 has been updated. 2025 revenue forecast increased from US$250.0k to US$640.0k. EPS estimate unchanged from -US$10.40 at last update. Biotechs industry in the US expected to see average net income decline 13% next year. Consensus price target down from US$139 to US$122. Share price rose 25% to US$17.44 over the past week.
Price Target Changed • Apr 17Price target decreased by 9.9% to US$126Down from US$140, the current price target is an average from 9 analysts. New target price is 807% above last closing price of US$13.90. Stock is down 79% over the past year. The company is forecast to post a net loss per share of US$10.40 next year compared to a net loss per share of US$9.37 last year.
お知らせ • Apr 01Korro Bio, Inc. Appoints Loïc Vincent as Chief Scientific OfficerKorro Bio, Inc. announced the appointment of Loïc Vincent as Chief Scientific Officer. Dr. Vincent joins Korro with more than 20 years in drug discovery and translational research across academia, biotech and the pharmaceutical industry. Throughout his career, Dr. Vincent led teams that advanced more than 20 drugs into clinical development based on various therapeutic modalities including small molecules, biologics, viral platforms and cell therapies. Prior to joining Korro, Dr. Vincent served as Chief Scientific Officer at Affini-T Therapeutics leading efforts to advance next-generation therapies. Previously, he was Head of the Oncology Drug Discovery Unit and Immunology Unit at Takeda. Before that, Dr. Vincent led Oncology Drug Discovery Pharmacology, Immunotherapy and Oncology External Innovation teams at Sanofi, and earlier in his career, he headed Pharmacology and Oncology programs at Endotis Pharma. Dr. Vincent currently serves on the Scientific Advisory Boards of bit.bio and General Inception, and is a Director on the Board of Alaya.bio. Dr. Vincent obtained his Ph.D. in pharmacology from the University of Rouen, France, and completed his postdoctoral fellowship in oncology at the Weill Medical College of Cornell University, New York.
分析記事 • Mar 19Will Korro Bio (NASDAQ:KRRO) Spend Its Cash Wisely?We can readily understand why investors are attracted to unprofitable companies. For example, although...
お知らせ • Feb 13Korro Bio, Inc. Appoints Oliver Dolan as Interim Principal Accounting OfficerEffective February 11, 2025, Vineet Agarwal, Chief Financial Officer (principal financial officer and principal accounting officer) of Korro Bio, Inc., is taking a temporary medical leave of absence. Accordingly, effective from February 11, 2025, Korro’s Board of Directors appointed Mr. Oliver Dolan, Senior Vice President, Finance, to serve as Korro’s interim principal accounting officer, in each case, in addition to their current duties. Mr. Dolan, age 42, has served as Korro’s Senior Vice President of Finance since January 2024. Prior to joining Korro, Mr. Dolan served as Vice President, Accounting, Tax and Treasury at Unity Biotechnology from December 2020 to December 2023. Prior to that, Mr. Dolan served as Head of Finance at Haven Healthcare from May 2020 to December 2020. Prior to that, Mr. Dolan served as Vice President of Finance at Compass Therapeutics from October 2018 to May 2020. Mr. Dolan holds an MBA from MIT Sloan School of Management, a Bachelor of Commerce degree from the University College Dublin and he is licensed as a Certified Public Accountant.
お知らせ • Jan 13Korro Bio Announces Dosing of First Participants in REWRITE Phase 1/2a Study of KRRO-110 for Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. announced the initiation of dosing in its REWRITE study investigating KRRO-110 as a potential treatment for individuals with Alpha-1 Antitrypsin Deficiency (AATD). REWRITE is a two-part single and multiple dose-escalating study that will evaluate the safety and tolerability of KRRO-110 in up to 64 participants, including healthy adults and clinically stable AATD patients with the PiZZ genotype. Secondary and exploratory endpoints include pharmacokinetic and pharmacodynamic parameters that will guide optimal dose selection for later stage studies. Interim data from Part 1 (single ascending doses in healthy volunteers and individuals with AATD) is expected in the second half of 2025, and completion of the study is anticipated in 2026. For additional information about the REWRITE study, visit ClinicalTrials.gov (NCT06677307). In addition to advancing KRRO-110, Korro is progressing a pipeline of wholly owned programs and a Novo Nordisk partnered program in a cardiometabolic indication towards the clinic.
お知らせ • Dec 03Korro Bio, Inc. has filed a Follow-on Equity Offering in the amount of $100 million.Korro Bio, Inc. has filed a Follow-on Equity Offering in the amount of $100 million. Security Name: Common Stock Security Type: Common Stock Transaction Features: At the Market Offering
分析記事 • Nov 28We Think Korro Bio (NASDAQ:KRRO) Needs To Drive Business Growth CarefullyJust because a business does not make any money, does not mean that the stock will go down. For example, although...
Recent Insider Transactions Derivative • Nov 17Chief Financial Officer notifies of intention to sell stockVineet Agarwal intends to sell 800 shares in the next 90 days after lodging an Intent To Sell Form on the 11th of November. If the sale is conducted around the recent share price of US$70.00, it would amount to US$56k. Since December 2023, Vineet has not owned shares directly (This sale likely refers to shares that have not yet been received). Company insiders have collectively sold US$767k more than they bought, via options and on-market transactions in the last 12 months.
お知らせ • Nov 05+ 1 more updateKorro Bio, Inc. Announces Submission to Bellberry HREC for Phase 1/2 Clinical Study of KRRO-110 for AATDKorro Bio, Inc. announced a submission to the Bellberry HREC for a Phase 1/2 clinical study of KRRO-110 for AATD. A Clinical Advisory Board (CAB) comprised of distinguished lung and liver researchers and experts in AATD has also been assembled to help guide the clinical development strategy for KRRO-110. Subject to approval by the HREC and acceptance of the clinical trial notification (CTN) by Australia’s Therapeutic Goods Administration (TGA), Korro anticipates dosing the first participant in the Phase 1/2 study in the first quarter of 2025. An interim data readout for the Phase 1/2 study of KRRO-110 is anticipated in the second half of 2025, and completion of the study is expected in 2026.
Recent Insider Transactions Derivative • Oct 20Chief Financial Officer notifies of intention to sell stockVineet Agarwal intends to sell 10k shares in the next 90 days after lodging an Intent To Sell Form on the 17th of October. If the sale is conducted around the recent share price of US$78.26, it would amount to US$800k. Since December 2023, Vineet has not owned shares directly (This sale likely refers to shares that have not yet been received). Company insiders have collectively sold US$761k more than they bought, via options and on-market transactions in the last 12 months.
お知らせ • Aug 28Korro Bio, Inc. Announces Board ChangesKorro Bio, Inc. announced that the Board of Directors has appointed Katharine Knobil, M.D. as an Independent Director, effective immediately. Korro also announced that David Lucchino has stepped down from the Board. Dr. Knobil brings a wealth of experience in clinical development and regulatory affairs to Korro. With over 25 years in the pharmaceutical and biotech industries, she has played a pivotal role in advancing numerous therapeutics from early-stage development to regulatory approval and commercialization. She most recently served as Chief Medical Officer at Agilent Technologies, where she established an industry-leading medical affairs organization and was responsible for integrating the voice of patients into business and clinical development strategy and decision-making. Previously, she was Chief Medical Officer and Head of Research and Development at Kaleido Biosciences. Before that, Dr. Knobil spent more than 20 years at GlaxoSmithKline (GSK) in roles of increasing responsibility, most recently serving as Chief Medical Officer. Dr. Knobil is currently a member of the Board of Directors at Nimbus Therapeutics, Marker Therapeutics and Pliant Therapeutics. Dr. Knobil is a recognized leader in the field, having authored numerous publications and presented at major industry conferences. She received an M.D. from the University of Texas Southwestern Medical School and completed her subsequent fellowship in Pulmonary Medicine and Critical Care Medicine at Johns Hopkins University.
分析記事 • Aug 15We Think Korro Bio (NASDAQ:KRRO) Needs To Drive Business Growth CarefullyWe can readily understand why investors are attracted to unprofitable companies. For example, although...
Board Change • May 17High number of new and inexperienced directorsThere are 6 new directors who have joined the board in the last 3 years. The company's board is composed of: 6 new directors. No experienced directors. 1 highly experienced director. Director David Lucchino is the most experienced director on the board, commencing their role in 2014. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.
お知らせ • May 16Korro Bio, Inc. Announces the Appointment of Kemi Olugemo, M.D. as Chief Medical OfficerKorro Bio, Inc. announced the appointment of Dr. Kemi Olugemo as Chief Medical Officer. Dr. Olugemo brings more than 10 years of industry experience focused on clinical development and regulatory strategy. She joins Korro after serving as VP & Therapeutic Head, Neurology Global Clinical Development at Ultragenyx Pharmaceutical. In this role, she directed and oversaw the overall strategy for clinical drug product development, supported the development of global regulatory plans, and identified critical opportunities for external collaborations. Dr. Olugemo holds an M.D. from the University of Maryland School of Medicine and a B.Sc. in Clinical Laboratory Science from the University of Massachusetts, Lowell. With her experience in rare and more prevalent diseases, Dr. Olugemo will provide invaluable expertise and leadership to advance Korro’s clinical and regulatory initiatives.
お知らせ • May 01Korro Bio, Inc., Annual General Meeting, Jun 11, 2024Korro Bio, Inc., Annual General Meeting, Jun 11, 2024, at 13:30 US Eastern Standard Time. Agenda: To consider Election of two Class II directors, Ali Behbahani and Timothy Pearson, nominated by board of directors, each to serve for a three-year term expiring at the 2027 annual meeting of stockholders; to consider Approval of an amendment to Restated Certificate of Incorporation to limit the liability of certain officers as permitted by amendments to Delaware law; to consider Ratification of the appointment of Ernst & Young LLP as independent registered public accounting firm for the fiscal year ending December 31, 2024; and to consider other matters.
お知らせ • Apr 23Korro Bio, Inc. announced that it has received $69.959848 million in funding from Atlas Venture L.P., Deep Track Capital, LP, Blue Owl Healthcare Opportunities, Rock Springs Capital Management LP, Tri Locum Partners LP, New Enterprise Associates, Inc.On April 22, 2024, Korro Bio, Inc. closed the transaction.
お知らせ • Apr 19Korro Bio, Inc. announced that it expects to receive $69.959848 million in funding from Atlas Venture L.P., Deep Track Capital, LP, Blue Owl Healthcare Opportunities, Rock Springs Capital Management LP, Tri Locum Partners LP, New Enterprise Associates, Inc.Korro Bio, Inc. announces it has entered into a subscription agreement with a number of institutional accredited investors to issue 1,249,283 shares of common stock at a issue price of $56 per share for gross proceeds of $69,959,848 on April 17, 2024. The transaction will include participation from Deep Track Capital, as lead investor and Atlas Venture, Blue Owl Healthcare Opportunities, NEA, Rock Springs Capital, Tri Locum Partners, and other leading healthcare investors. The transaction is expected to close on April 22, 2024.
分析記事 • Mar 30We Think Korro Bio (NASDAQ:KRRO) Can Afford To Drive Business GrowthWe can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
New Risk • Dec 08New minor risk - Financial data availabilityLess than 3 years of financial data is available. This is considered a minor risk. If the company has been trading for less than 3 years, then it has not had the opportunity to establish a long-term track record. This makes it difficult for investors to assess the true growth potential, sustainability and resilience of the business under different economic conditions. Currently, the following risks have been identified for the company: Major Risks Shares are highly illiquid. Earnings are forecast to decline by an average of 8.4% per year for the foreseeable future. Revenue is less than US$1m. Minor Risks Less than 3 years of financial data is available. Currently unprofitable and not forecast to become profitable over next 3 years (US$93m net loss in 3 years). Significant insider selling over the past 3 months (US$84k sold).
お知らせ • Dec 07Korro Announces Selection of Its First Development Candidate for the Potential Treatment of Alpha-1 Antitrypsin DeficiencyKorro Bio, Inc. has nominated its first development candidate, KRRO-110, for the potential treatment of AATD. KRRO-110 is a proprietary RNA editing oligonucleotide delivered to liver cells using clinically validated LNP technology licensed from Genevant. KRRO-110 is designed to co-opt an endogenous enzyme Adenosine Deaminase Acting on RNA (ADAR) to repair a pathogenic single nucleotide variant (SNV) on RNA and restore production of normal A1AT. AATD is an inherited genetic disorder caused by SNVs in the SERPINA1 gene that can lead to severe progressive lung disease, including emphysema and chronic obstructive pulmonary disease (COPD), and liver disease. There are an estimated 3.4 million individuals with deficiency allele combinations worldwide. The only current FDA-approved treatment for AATD is augmentation therapy, a once-weekly infusion of pooled human plasma-derived A1AT protein, which does not adequately address the manifestations of AATD.
お知らせ • Nov 30Korro Bio, Inc. Appoints Rachel Meyers as Board of Directors, Member of Nominating and Corporate Governance CommitteeKorro Bio, Inc. announced the appointment of Rachel Meyers, PhD, to the company’s board of directors. Dr. Meyers is a seasoned biotechnology veteran whose experience in life sciences spans over two decades. Most recently, Dr. Meyers served as Chief Scientific Officer of Faze Medicines. Previously, she was an Entrepreneur-in-Residence at Third Rock Ventures. Before that, Dr. Meyers held multiple leadership positions at Alnylam Pharmaceuticals for over 13 years, most recently as Senior Vice President of Research and RNAi Lead Development. Rachel completed her post-doctoral training at Harvard University and holds a PhD in Biology from the Massachusetts Institute of Technology and a BA in Biochemistry from Brandeis University. Dr. Meyers was also appointed by the Board upon the recommendation of the NCG Committee to serve as a member of the Nominating and Corporate Governance Committee or NCG Committee.
Board Change • Nov 07No independent directorsFollowing the recent departure of a director, there are no independent directors on the board. The company's board is composed of: No independent directors. 7 non-independent directors. Director Omar Khwaja was the last director to join the board, commencing their role in 2020. The company's lack of independent directors is a risk according to the Simply Wall St Risk Model.
お知らせ • Nov 07Frequency Therapeutics, Inc. announced that it has received $117.249989 million in funding from a group of investorsOn November 6, 2023, Frequency Therapeutics, Inc. closed the transaction. The company issued 42,176,255 common shares at a price of $2.78 per share for gross proceeds of $117.249989 million.
