Forte Biosciences（FBRX）株式概要フォルテ・バイオサイエンス社は、米国で臨床段階のバイオ医薬品会社として事業を展開している。 詳細FBRX ファンダメンタル分析スノーフレーク・スコア評価0/6将来の成長0/6過去の実績0/6財務の健全性6/6配当金0/6リスク分析収益が 100 万ドル未満 ( $0 )US市場と比較して、過去 3 か月間の株価の変動が非常に大きい過去1年間で株主の希薄化は大幅に進んだ 今後3年間の収益は年平均37.1%減少すると予測されている。 +1 さらなるリスクすべてのリスクチェックを見るFBRX Community Fair Values Create NarrativeSee what others think this stock is worth. Follow their fair value or set your own to get alerts.NEW480,575 membersJoin community and earn perksGain real feedbackFrom our editorial team, personally. Not silence.Grow your followingReal investors. The kind who actually invest, not scroll past.Unlock free accessFree premium subscription for consistent and quality authors.Learn moreCreate NarrativeBLINRODA480,575 investors already sharing narrativesYour Fair ValueUS$Current PriceUS$76.60該当なし内在価値ディスカウントEst. Revenue$PastFuture-76m212016201920222025202620282031Revenue US$21.1Earnings US$3.7AdvancedSet Fair ValueView all narrativesForte Biosciences, Inc. 競合他社Taysha Gene TherapiesSymbol: NasdaqGS:TSHAMarket cap: US$1.9bStoke TherapeuticsSymbol: NasdaqGS:STOKMarket cap: US$1.9bTyra BiosciencesSymbol: NasdaqGS:TYRAMarket cap: US$1.9bMonte Rosa TherapeuticsSymbol: NasdaqGS:GLUEMarket cap: US$1.9b価格と性能株価の高値、安値、推移の概要Forte Biosciences過去の株価現在の株価US$76.6052週高値US$77.2052週安値US$9.10ベータ2.841ヶ月の変化259.29%3ヶ月変化171.73%1年変化697.09%3年間の変化250.49%5年間の変化-88.62%IPOからの変化-81.76%最新ニュースライブニュース • Jul 29argenx to Acquire Forte Biosciences for $2.2 Billion in Immunology Dealargenx has agreed to acquire Forte Biosciences for about US$2.2 billion in total equity value, with the deal expected to close in the third quarter of 2026 subject to standard closing conditions. The acquisition is expected to bring Forte’s anti-CD122 antibody FB102 into argenx’s immunology portfolio. This transaction is material for Forte Biosciences because it effectively transfers FB102 to a larger immunology platform, which can influence how the asset is funded, developed and potentially commercialized. Forte Biosciences shares trade at US$76.53, with the stock up 259.0% over the past 30 days, reflecting a sharp repricing ahead of the proposed acquisition. The key focus now is deal risk. Investors will be watching regulatory approvals, timing to close and any potential shifts in terms, since the investment case largely hinges on the transaction completing as agreed.Price Target Changed • Jul 27Price target increased by 12% to US$71.60Up from US$63.75, the current price target is an average from 5 analysts. New target price is 6.4% below last closing price of US$76.50. The company is forecast to post a net loss per share of US$3.97 next year compared to a net loss per share of US$4.71 last year.お知らせ • Jul 27argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion.argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion on July 26, 2026. Under the terms of the offer, argenx SE will commence a cash tender offer to acquire all of the outstanding shares of Forte Biosciences’ common stock at a price of $77 in cash per share, representing a total equity value of approximately $2.2 billion. The transaction will be funded entirely from cash on hand. Following the successful completion of the tender offer, a wholly owned subsidiary of argenx will merge with Forte Biosciences and the outstanding Forte Biosciences shares not tendered in the tender offer will be converted into the right to receive the same $77 per share in cash paid in the tender offer. In case of termination of the transaction, seller will be required to pay argenx SE a termination fee of $65 million. The transaction is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of Forte Biosciences, and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act. The deal has been approved by the board of directors of argenx SE and Forte Biosciences, Inc. The acquisition is expected to close in Q3 2026. Goldman Sachs International acted as exclusive financial advisor to argenx SE. Damien Zoubek and Oliver J. Board of Freshfields US LLP acted as legal advisor to argenx SE. Guggenheim Securities, LLC acted as exclusive financial advisor to Forte Biosciences, Inc. Rob Ishii, Remi Korenblit, Dan Koeppen, Ben Capps, Rob Wernli, Megan Schilling, Brandon Gantus, Michael Hostetler, Minyoung Shin, Mark Bellomy, Joshua Gruenspecht, Anne Seymour, Eva Yin, Matthew Staples, Michael O'Brien, Myra Sutanto Shen, Jamillia Ferris, Michelle Yost Hale, and Deirdre Carroll of Wilson Sonsini Goodrich & Rosati, P.C. acted as legal advisor to Forte Biosciences, Inc. Computershare Trust Company, National Association acted as transfer agent for Forte Biosciences, Inc.ライブニュース • Jul 12FB102 Achieves Primary Endpoint in Vitiligo Trial With Durable Improvement at Forte BiosciencesForte Biosciences reported that FB102 met its primary endpoint in a small placebo-controlled vitiligo trial, with statistically significant improvement in facial Vitiligo Area Scoring Index by week 24 and benefits persisting off treatment through week 24. Experts described the FB102 study as a success but highlighted the need for larger confirmatory trials to better quantify efficacy and fully characterize the safety profile. Forte Biosciences’ share price is at $43.92, with the stock up 150.1% over the past 30 days, reflecting a sharp recent repricing around the company’s prospects. The key question now is how future, larger FB102 studies read out, since the current data are early stage and come from a small sample, which can make the stock sensitive to any shift in efficacy or safety signals.New Risk • Jul 09New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 25% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (25% average weekly change). Earnings are forecast to decline by an average of 30% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (100% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$189m net loss in 3 years).お知らせ • Jul 09Forte Biosciences Announces Positive Results From FB102 Double-Blind Placebo-Controlled Phase 1b Study In VitiligoForte Biosciences, Inc. announced positive results from the FB102 double-blind placebo-controlled phase 1b study in vitiligo. FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvements observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 (p-value = 0.006) in subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), including: FVASI50 = 58.8%, FVASI75 = 23.5%. Responder endpoints in overall population achieved FVASI50 in 34.4% of FB102 treated subjects at week 24 with FVASI 75 achieved in 12.5% of FB102 treated subjects at week 24; this endpoint was impacted by one placebo FVASI75 responder, reinforcing the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. The majority of FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) of FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subjects worsened during the 24 week period. FB102 continues to demonstrate a strong safety profile and compared favorably to placebo with only mild to moderate AEs. These independent centrally-reviewed, placebo-controlled data demonstrate statistically significant FB102 mean FVASI improvements from baseline, with progressive improvement and a strong responder profile through week 24 after completion of the 12-week treatment period. The FB102 double-blind placebo-controlled phase 1b vitiligo study enrolled 43 subjects 3:1 randomized with 11 on placebo and 32 on FB102. Forte enrolled 2 FB102 treatment cohorts in the trial including the 3 mg/kg maintenance cohort previously disclosed. There were 15 on FB102 in Cohort A and 17 in Cohort B. The primary endpoint of the study was mean percent FVASI improvement from baseline assessed by central-review. The mean percent FVASI improvement from baseline in the ITT population was 29.6% for FB102 (n=32) compared to a mean deterioration of 16.2% for placebo (n=11), for a placebo-adjusted FB102 benefit of 45.8% (p=0.005). The group of 11 placebo subjects in the ITT population had one subject that was not part of the protocol-defined efficacy-evaluable population due to facial hair and that subject also experienced vitiligo progression during the study. The protocol defined efficacy-evaluable population excluded this one placebo subject (n=10) which also provides a more conservative assessment of the FB102 activity. In the protocol-defined efficacy evaluable population (FB102: 32, PBO:10), FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 vs 7.9% on placebo for a placebo-adjusted FB102 benefit of 21.7% (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvement observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. In Cohort A, FB102 achieved a 28.8% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 20.9% (p-value = 0.04) while in Cohort B, FB102 achieved a 30.4% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 22.5% (p-value = 0.027). In subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 compared to 0.5% for placebo treated subjects for a placebo-adjusted FB102 benefit of 42.7% (p-value = 0.006) with 10 of 17 FB102 treated subjects achieving an FVASI50 (58.8%) and 4 of 17 achieving an FVASI75 (23.5%) compared to 0 of 4 achieving FVASI50 and FVASI 75 for placebo subjects (0%). In the protocol-defined efficacy evaluable population 11 of 32 FB102 treated subjects achieved FVASI50 (34.4%) with 4 of 32 FB102 treated subjects achieving an FVASI 75 (12.5%) compared to 1 of 10 placebo subjects achieving FVASI50/75; the placebo FVASI75 responder reinforces the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subject worsened during the 24 week period. All AEs were mild/moderate with FB102 comparing favorably to placebo, and taken together with the phase1b celiac study, FB102 continues to demonstrate a strong safety profile.最新情報をもっと見るRecent updatesライブニュース • Jul 29argenx to Acquire Forte Biosciences for $2.2 Billion in Immunology Dealargenx has agreed to acquire Forte Biosciences for about US$2.2 billion in total equity value, with the deal expected to close in the third quarter of 2026 subject to standard closing conditions. The acquisition is expected to bring Forte’s anti-CD122 antibody FB102 into argenx’s immunology portfolio. This transaction is material for Forte Biosciences because it effectively transfers FB102 to a larger immunology platform, which can influence how the asset is funded, developed and potentially commercialized. Forte Biosciences shares trade at US$76.53, with the stock up 259.0% over the past 30 days, reflecting a sharp repricing ahead of the proposed acquisition. The key focus now is deal risk. Investors will be watching regulatory approvals, timing to close and any potential shifts in terms, since the investment case largely hinges on the transaction completing as agreed.Price Target Changed • Jul 27Price target increased by 12% to US$71.60Up from US$63.75, the current price target is an average from 5 analysts. New target price is 6.4% below last closing price of US$76.50. The company is forecast to post a net loss per share of US$3.97 next year compared to a net loss per share of US$4.71 last year.お知らせ • Jul 27argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion.argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion on July 26, 2026. Under the terms of the offer, argenx SE will commence a cash tender offer to acquire all of the outstanding shares of Forte Biosciences’ common stock at a price of $77 in cash per share, representing a total equity value of approximately $2.2 billion. The transaction will be funded entirely from cash on hand. Following the successful completion of the tender offer, a wholly owned subsidiary of argenx will merge with Forte Biosciences and the outstanding Forte Biosciences shares not tendered in the tender offer will be converted into the right to receive the same $77 per share in cash paid in the tender offer. In case of termination of the transaction, seller will be required to pay argenx SE a termination fee of $65 million. The transaction is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of Forte Biosciences, and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act. The deal has been approved by the board of directors of argenx SE and Forte Biosciences, Inc. The acquisition is expected to close in Q3 2026. Goldman Sachs International acted as exclusive financial advisor to argenx SE. Damien Zoubek and Oliver J. Board of Freshfields US LLP acted as legal advisor to argenx SE. Guggenheim Securities, LLC acted as exclusive financial advisor to Forte Biosciences, Inc. Rob Ishii, Remi Korenblit, Dan Koeppen, Ben Capps, Rob Wernli, Megan Schilling, Brandon Gantus, Michael Hostetler, Minyoung Shin, Mark Bellomy, Joshua Gruenspecht, Anne Seymour, Eva Yin, Matthew Staples, Michael O'Brien, Myra Sutanto Shen, Jamillia Ferris, Michelle Yost Hale, and Deirdre Carroll of Wilson Sonsini Goodrich & Rosati, P.C. acted as legal advisor to Forte Biosciences, Inc. Computershare Trust Company, National Association acted as transfer agent for Forte Biosciences, Inc.ライブニュース • Jul 12FB102 Achieves Primary Endpoint in Vitiligo Trial With Durable Improvement at Forte BiosciencesForte Biosciences reported that FB102 met its primary endpoint in a small placebo-controlled vitiligo trial, with statistically significant improvement in facial Vitiligo Area Scoring Index by week 24 and benefits persisting off treatment through week 24. Experts described the FB102 study as a success but highlighted the need for larger confirmatory trials to better quantify efficacy and fully characterize the safety profile. Forte Biosciences’ share price is at $43.92, with the stock up 150.1% over the past 30 days, reflecting a sharp recent repricing around the company’s prospects. The key question now is how future, larger FB102 studies read out, since the current data are early stage and come from a small sample, which can make the stock sensitive to any shift in efficacy or safety signals.New Risk • Jul 09New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 25% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (25% average weekly change). Earnings are forecast to decline by an average of 30% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (100% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$189m net loss in 3 years).お知らせ • Jul 09Forte Biosciences Announces Positive Results From FB102 Double-Blind Placebo-Controlled Phase 1b Study In VitiligoForte Biosciences, Inc. announced positive results from the FB102 double-blind placebo-controlled phase 1b study in vitiligo. FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvements observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 (p-value = 0.006) in subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), including: FVASI50 = 58.8%, FVASI75 = 23.5%. Responder endpoints in overall population achieved FVASI50 in 34.4% of FB102 treated subjects at week 24 with FVASI 75 achieved in 12.5% of FB102 treated subjects at week 24; this endpoint was impacted by one placebo FVASI75 responder, reinforcing the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. The majority of FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) of FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subjects worsened during the 24 week period. FB102 continues to demonstrate a strong safety profile and compared favorably to placebo with only mild to moderate AEs. These independent centrally-reviewed, placebo-controlled data demonstrate statistically significant FB102 mean FVASI improvements from baseline, with progressive improvement and a strong responder profile through week 24 after completion of the 12-week treatment period. The FB102 double-blind placebo-controlled phase 1b vitiligo study enrolled 43 subjects 3:1 randomized with 11 on placebo and 32 on FB102. Forte enrolled 2 FB102 treatment cohorts in the trial including the 3 mg/kg maintenance cohort previously disclosed. There were 15 on FB102 in Cohort A and 17 in Cohort B. The primary endpoint of the study was mean percent FVASI improvement from baseline assessed by central-review. The mean percent FVASI improvement from baseline in the ITT population was 29.6% for FB102 (n=32) compared to a mean deterioration of 16.2% for placebo (n=11), for a placebo-adjusted FB102 benefit of 45.8% (p=0.005). The group of 11 placebo subjects in the ITT population had one subject that was not part of the protocol-defined efficacy-evaluable population due to facial hair and that subject also experienced vitiligo progression during the study. The protocol defined efficacy-evaluable population excluded this one placebo subject (n=10) which also provides a more conservative assessment of the FB102 activity. In the protocol-defined efficacy evaluable population (FB102: 32, PBO:10), FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 vs 7.9% on placebo for a placebo-adjusted FB102 benefit of 21.7% (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvement observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. In Cohort A, FB102 achieved a 28.8% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 20.9% (p-value = 0.04) while in Cohort B, FB102 achieved a 30.4% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 22.5% (p-value = 0.027). In subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 compared to 0.5% for placebo treated subjects for a placebo-adjusted FB102 benefit of 42.7% (p-value = 0.006) with 10 of 17 FB102 treated subjects achieving an FVASI50 (58.8%) and 4 of 17 achieving an FVASI75 (23.5%) compared to 0 of 4 achieving FVASI50 and FVASI 75 for placebo subjects (0%). In the protocol-defined efficacy evaluable population 11 of 32 FB102 treated subjects achieved FVASI50 (34.4%) with 4 of 32 FB102 treated subjects achieving an FVASI 75 (12.5%) compared to 1 of 10 placebo subjects achieving FVASI50/75; the placebo FVASI75 responder reinforces the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subject worsened during the 24 week period. All AEs were mild/moderate with FB102 comparing favorably to placebo, and taken together with the phase1b celiac study, FB102 continues to demonstrate a strong safety profile.お知らせ • Jun 29+ 1 more updateForte Biosciences, Inc.(NasdaqCM:FBRX) dropped from Russell Microcap Value Benchmark IndexForte Biosciences, Inc.(NasdaqCM:FBRX) dropped from Russell Microcap Value Benchmark Indexお知らせ • May 02Forte Biosciences, Inc., Annual General Meeting, May 29, 2026Forte Biosciences, Inc., Annual General Meeting, May 29, 2026.お知らせ • Apr 09+ 1 more updateForte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $150.000019 million.Forte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $150.000019 million. Security Name: Common Stock Security Type: Common Stock Securities Offered: 5,709,936 Price\Range: $26.27 Discount Per Security: $1.5762Breakeven Date Change • Apr 02No longer forecast to breakevenThe 4 analysts covering Forte Biosciences no longer expect the company to break even during the foreseeable future. The company was expected to make a profit of US$133.6m in 2026. New consensus forecast suggests the company will make a loss of US$119.0m in 2027.New Risk • Jan 13New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 17% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (17% average weekly change). Earnings are forecast to decline by an average of 30% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (179% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$161m net loss in 3 years).Recent Insider Transactions • Jan 04Chief Financial Officer recently bought US$255k worth of stockOn the 30th of December, Antony Riley bought around 10k shares on-market at roughly US$26.33 per share. This transaction amounted to 30% of their direct individual holding at the time of the trade. This was the largest purchase by an insider in the last 3 months. This was Antony's only on-market trade for the last 12 months.分析記事 • Nov 11We're Not Very Worried About Forte Biosciences' (NASDAQ:FBRX) Cash Burn RateWe can readily understand why investors are attracted to unprofitable companies. For example, Forte Biosciences...お知らせ • Sep 16Forte Biosciences, Inc. Announces Presentation of Fb102 Celiac Disease Trial At Tampere Celiac Disease SymposiumForte Biosciences, Inc. announced additional details from the oral presentation "FB102 prevents histological damage and mitigates gluten challenge-induced symptoms in a celiac disease phase 1b study - Jason Tye-Din, Walter and Eliza Hall Institute; Royal Melbourne Hospital" at the Tampere Celiac Disease Symposium 2025 (Tampere, Finland) on September 12, 2025, further supporting the significant differentiation of FB102 in celiac disease. Highlights of the oral presentation include: FB102 demonstrated a decline in the TCR gd density from baseline of 1.5 compared to an increase of 3.9 for placebo (p=0.0007); TCR gd cells produce pro-inflammatory cytokines including IFN-g and TNF-a and upregulate activating receptors on epithelial cells triggering cytotoxic responses that directly kill the epithelial cells. Ki67-positive intraepithelial cell density increased from baseline by 8.6 on placebo compared to 2.5 on FB102 (p=0.0006); Ki67 is a marker of T cell proliferation (inflammation) on gluten exposure in celiac disease; NK cells declined by 95% following FB102 dosing; IL-15 upregulates activating receptors and confers resistance to activation-induced cell death and enhances T cell epithelial cytotoxicity in celiac disease; No statistically significant difference in Tregs between FB102 and placebo at any timepoint; Regulatory T cells (Tregs) help to modulate the immune response in autoimmune diseases like celiac disease. The phase 2 FB102 celiac disease trial is underway with topline data coming in 2026. The FB102 impact on the additional IEL subtypes in the phase 1b trial is extremely encouraging with respect to the additional therapeutic indications Forte is pursuing, including vitiligo and alopecia areata with data from both of these trials expected next year. In some cases, you can identify forward-looking statements by terms such as " may, "will," "should," "plan," "anticipate," "intend," target, project,contemplates," "bel believes,estimates," "predicts," "pot potential" or "continue" or the negatives of these terms or other similar statements are based on the Company's current beliefs and expectations. Forward-looking statements include statements regarding the Company's beliefs, goals, intentions and expectations regarding its product candidate, FB102 and the therapeutic and commercial market potential of FB102, expectations for patient enrollment and timing of clinical data readouts. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation: risks related to Forte's ability to obtain sufficient additional capital to continue to advance Forte's product candidate, FB102; uncertainties associated with the clinical development and regulatory approval of Forte's product candidate,FB102, including potential delays in the commencement, enrollment and completion of clinical trials, including the timing of the completion of the Company's patient-based trials; the risk that results from preclinical and any interim result of ongoing clinical trials may not be predictive of future results from clinical trials may not be predictive the failure to realize any value from FB102 in light of inherent risks, expense and difficulties involved in successfully bringing product candidates to market; and additional risks, uncertainties, and other information affecting Forte's business and operating results is contained in Forte's quarterly Report on Forms 10-QQQQQQQ.Price Target Changed • Aug 18Price target increased by 14% to US$52.25Up from US$45.67, the current price target is an average from 4 analysts. New target price is 339% above last closing price of US$11.91. Stock is up 44% over the past year. The company is forecast to post a net loss per share of US$4.47 next year compared to a net loss per share of US$12.17 last year.Price Target Changed • Aug 17Price target decreased by 8.2% to US$44.67Down from US$48.67, the current price target is an average from 3 analysts. New target price is 286% above last closing price of US$11.57. Stock is up 54% over the past year. The company is forecast to post a net loss per share of US$4.52 next year compared to a net loss per share of US$12.17 last year.お知らせ • Jun 25+ 1 more updateForte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $75.000052 million.Forte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $75.000052 million. Security Name: Common Stock Security Type: Common Stock Securities Offered: 5,630,450 Price\Range: $12 Discount Per Security: $0.72 Security Name: Pre-Funded Warrants Security Type: Equity Warrant Securities Offered: 619,606 Price\Range: $11.999 Discount Per Security: $0.72お知らせ • Jun 24Forte Biosciences, Inc. Announces Positive Data in Ff102 Celiac Disease Phase 1B StudyForte Biosciences, Inc. announced positive data from a Phase 1b trial in celiac disease for lead program FB102 (FB102-101). Treatment emergent adverse events (TEAE) were primarily mild (grade 1) with no grade 3 or higher SAEs reported in the FB102 arm. Celiac disease is debilitating for many patients with even trace exposure to gluten. FB102 has taken a big step forward towards addressing this very large unmet need with the results from this study. The Phase 2 celiac disease study is initiating with a topline readout expected in 2026. These results are also very encouraging given the biology of the additional FB102 indications including vitiligo, alopecia areata and type 1 diabetes. The company also look forward to reading out the topline results of the FB102 vitiligo study in the first half of 2026.New Risk • Jun 05New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$35m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$35m free cash flow). Share price has been highly volatile over the past 3 months (23% average weekly change). Shareholders have been substantially diluted in the past year (352% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Currently unprofitable and not forecast to become profitable next year (US$44m net loss next year). Market cap is less than US$100m (US$65.7m market cap).お知らせ • Apr 21Forte Biosciences, Inc., Annual General Meeting, May 29, 2025Forte Biosciences, Inc., Annual General Meeting, May 29, 2025.分析記事 • Apr 19We Think Forte Biosciences (NASDAQ:FBRX) Needs To Drive Business Growth CarefullyWe can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...Price Target Changed • Apr 04Price target decreased by 45% to US$59.00Down from US$107, the current price target is an average from 2 analysts. New target price is 903% above last closing price of US$5.88. Stock is down 66% over the past year. The company is forecast to post a net loss per share of US$3.73 next year compared to a net loss per share of US$12.17 last year.New Risk • Mar 24New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 18% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (18% average weekly change). Earnings are forecast to decline by an average of 26% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (339% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$80m net loss in 3 years). Market cap is less than US$100m (US$52.2m market cap).New Risk • Jan 13New major risk - Shareholder dilutionThe company's shareholders have been substantially diluted in the past year. Increase in shares outstanding: 340% This is considered a major risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (39% average weekly change). Earnings have declined by 3.9% per year over the past 5 years. Shareholders have been substantially diluted in the past year (340% increase in shares outstanding). Revenue is less than US$1m.お知らせ • Nov 21Forte Biosciences, Inc. announced that it expects to receive $53 million in funding from OrbiMed Advisors LLC, Janus Henderson Group plc, Tybourne Capital Management Limited, Ikarian Capital, LLC, BVF Partners L.P., Fred Alger Management, LLCForte Biosciences, Inc. announced an private placement of common shares for gross proceeds of $53,000,000 on November 19, 2024. The transaction included participation from new and existing investors including OrbiMed Advisors LLC, Janus Henderson Group plc, Tybourne Capital Management Limited, Ikarian Capital, LLC, BVF Partners L.P., Red Hook Fund LP, Fred Alger Management, LLC. The Private Placement is expected to close on November 21, 2024.Board Change • Oct 01High number of new directorsThere are 6 new directors who have joined the board in the last 3 years. Independent Director Rich Vincent was the last director to join the board, commencing their role in 2024. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.Board Change • Sep 25High number of new directorsThere are 5 new directors who have joined the board in the last 3 years. Director Shivpreet Kapoor was the last director to join the board, commencing their role in 2024. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.New Risk • Sep 19New major risk - Market cap sizeThe company's market capitalization is less than US$10m. Market cap: US$9.83m This is considered a major risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$31m free cash flow). Earnings have declined by 2.4% per year over the past 5 years. Revenue is less than US$1m. Market cap is less than US$10m (US$9.83m market cap). Minor Risk Share price has been volatile over the past 3 months (14% average weekly change).New Risk • Aug 20New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 15% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$31m free cash flow). Share price has been highly volatile over the past 3 months (15% average weekly change). Earnings have declined by 2.4% per year over the past 5 years. Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$12.0m market cap).Price Target Changed • Aug 16Price target increased by 25% to US$4.38Up from US$3.50, the current price target is an average from 2 analysts. New target price is 1,358% above last closing price of US$0.30. Stock is down 64% over the past year. The company posted a net loss per share of US$1.00 last year.お知らせ • Jul 22Forte Biosciences, Inc., Annual General Meeting, Aug 20, 2024Forte Biosciences, Inc., Annual General Meeting, Aug 20, 2024.分析記事 • Jul 17We're A Little Worried About Forte Biosciences' (NASDAQ:FBRX) Cash Burn RateThere's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...New Risk • Jun 28New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 9.8% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$30m free cash flow). Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Share price has been volatile over the past 3 months (9.8% average weekly change). Market cap is less than US$100m (US$17.5m market cap).New Risk • May 15New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$30m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$30m free cash flow). Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$24.7m market cap).分析記事 • Mar 14Is Forte Biosciences (NASDAQ:FBRX) In A Good Position To Deliver On Growth Plans?Just because a business does not make any money, does not mean that the stock will go down. For example, although...New Risk • Nov 24New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 10% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$23m free cash flow). Earnings have declined by 4.6% per year over the past 5 years. Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Share price has been volatile over the past 3 months (10% average weekly change). Market cap is less than US$100m (US$15.6m market cap).New Risk • Nov 16New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$16m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$16m free cash flow). Earnings have declined by 4.6% per year over the past 5 years. Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$14.2m market cap).Board Change • Oct 01High number of new directorsThere are 5 new directors who have joined the board in the last 3 years. Independent Director Mike Hacke was the last director to join the board, commencing their role in 2023. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.お知らせ • Sep 22Forte Biosciences Receives Non-Compliance Letter from NasdaqOn September 14, 2023, Forte Biosciences, Inc. (the Company") received a written notice (the Notice") from the Nasdaq Listing Qualifications staff of The Nasdaq Stock Market LLC (Nasdaq") indicating that, for the last 30 consecutive business days, the minimum bid price of the Company's common stock had been below the $1.00 per share minimum requirement for continued listing on the Nasdaq Capital Market under Nasdaq Listing Rule 5550(a)(2) (the Minimum Bid Price Requirement"). In accordance with Nasdaq Listing Rule 5810(c)(3)(A), the Company has been provided an initial period of 180 calendar days, or until March 12, 2024, to regain compliance with the Minimum Bid Price Requirement. The Notice states that the Nasdaq staff will provide written notification that the Company has achieved compliance with Rule 5550(a)(2) if, at any time before March 12, 2024, the closing bid price of the Company's common stock is $1.00 per share or more for a minimum of ten consecutive business days. The Notice has no immediate effect on the listing or trading of the Company's common stock. In the event the Company does not regain compliance with the Minimum Bid Price Requirement by March 12, 2024, the Company may be eligible for additional time to regain compliance. To qualify, the Company will be required to meet the continued listing requirement for market value of publicly held shares and all other initial listing standards for The Nasdaq Capital Market, with the exception of the Minimum Bid Price Requirement, and will need to provide written notice of its intention to cure the deficiency during the second compliance period, by effecting a reverse stock split, if necessary. If the Company meets these requirements, the Company will be granted an additional 180 calendar days to regain compliance. If the Company does not qualify for or fails to regain compliance during the second compliance period, then the Nasdaq staff will provide written notification to the Company that its common stock will be subject to delisting. The Company would then be entitled to appeal that determination to a Nasdaq hearings panel. The Company intends to actively monitor the closing bid price of its common stock and consider its available options to regain compliance with the Minimum Bid Price Requirement. There can be no assurance that the Company will regain compliance with the Minimum Bid Price Requirement during the 180-day compliance period ending March 12, 2024, secure an extension of the compliance period beyond March 12, 2024 or maintain compliance with any other Nasdaq listing requirements.お知らせ • Sep 21Forte Biosciences, Inc. Announces Directorate AppointmentsForte Biosciences, Inc. at its AGM held on September 19, 2023, approved appointment of Chris McIntyre and Michael G. Hacke as directors.お知らせ • Sep 07Camac Partners Shares Key Facts that Reinforce the Need for Urgent Change in Forte Biosciences’s BoardroomOn September 6, 2023, Camac Partners, LLC and ATG Capital Management, LLC, the Group and its independent director candidates – Michael Hacke and Chris McIntyre – responded to misrepresentations and distortions included in Forte Biosciences, Inc’s recent presentation. Camac Partners stated that Hacke and McIntyre have been nominated by the Group for election to the Company’s Board of Directors at the upcoming Annual Meeting of Stockholders currently scheduled for September 19, 2023. Camac Partners stated that as a reminder, the Group recently filed its own presentation that details why it believes the Company is in urgent need of boardroom change following years of poor performance and worst-in-class governance under Chairman and CEO Paul Wagner. In addition, the Group encourages stockholders to consider the facts before deciding which individuals to support at the upcoming Annual Meeting.お知らせ • Aug 26Forte Biosciences, Inc., Annual General Meeting, Sep 19, 2023Forte Biosciences, Inc., Annual General Meeting, Sep 19, 2023.New Risk • Aug 18New major risk - Shareholder dilutionThe company's shareholders have been substantially diluted in the past year. Increase in shares outstanding: 78% This is considered a major risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Major Risks Earnings have declined by 2.6% per year over the past 5 years. Shareholders have been substantially diluted in the past year (78% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$30.3m market cap).お知らせ • Jan 13Forte Biosciences, Inc appoints David Gryska to the Board of DirectorsForte Biosciences, Inc. announced that Mr. David Gryska has been appointed to the Forte Biosciences Board of Directors. Mr. Gryska was previously the Chief Financial Officer and Executive Vice President at Incyte. Prior to joining Incyte, Mr. Gryska held the position of Chief Financial Officer and Senior Vice President at Celgene prior to its acquisition by Bristol-Myers Squibb. Mr. Gryska has spent over 30 years as a senior executive at life science and biotechnology companies with extensive experience relating to strategic transactions, acquisitions, financings and global expansion.Recent Insider Transactions • Dec 20CEO & Chairman recently bought US$105k worth of stockOn the 16th of December, Paul A. Wagner bought around 100k shares on-market at roughly US$1.05 per share. This transaction amounted to 7.8% of their direct individual holding at the time of the trade. This was the largest purchase by an insider in the last 3 months. This was Paul A.'s only on-market trade for the last 12 months.Board Change • Nov 16High number of new and inexperienced directorsThere are 6 new directors who have joined the board in the last 3 years. The company's board is composed of: 6 new directors. 2 experienced directors. No highly experienced directors. CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.Seeking Alpha • Aug 24Large Forte Biosciences shareholder scolds company board of directorsFunicular Funds, which owns 8% of the outstanding shares of Forte Biosciences (NASDAQ:FBRX), excoriated the company's board of directors in a letter over a recent capital raise. In an SEC filing, Funicular said the letter addressed the "Board’s failure to address the legitimate concerns previously raised by stockholders and its decision to embark on a value-destructive, scorched-earth path with a dilutive and unnecessary capital raise, without so much as an explanation for its actions." Funicular is asking to establish a committee of independent directors to investigate shareholder concerns. In July, a pair of large shareholders demanded changes at Forte (FBRX), including a suggestion that the company liquidate.分析記事 • Aug 17We're Hopeful That Forte Biosciences (NASDAQ:FBRX) Will Use Its Cash WiselyThere's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...Seeking Alpha • Aug 16Forte Biosciences: Lots Of Clinical Risk Ahead And A Questionable Business PlanFB-401, the lead asset failed in clinical trials. The company has one very early-stage asset they intend to move forward in the clinic, FB-102. Investors are likely to encounter dilution, a high degree of clinical risk and there is insufficient evidence to assess whether FB-401 has any advantages over other therapeutics. Summary Creativity is not my strength so I am reusing the title from an article that I wrote a few months back about Vyne Therapeutics, another dermatology company. The shares of Vyne have fallen 60% since then. The story is at Forte is essentially the same and all too common in biotech. Vyne and Forte both experienced setbacks, institutional investors sold and long term investors have fared poorly. Most importantly, for both companies, there is a suboptimal plan to move forward that exposes investors to a high degree of clinical risk, requires hundreds of millions of capital and has a low chance of rewarding investors in a manner commensurate with this outsized risk. I will outline a few reasons I rate Forte Biosciences (FBRX) a SELL Institutional Investors Major institutional investors have sold and cut their losses. Forte Biosciences had an enviable roster of professional investors including BVF, Orbimed and Perceptive Advisors. These are seasoned investors with a staff of PhD/MDs who are highly capable of assessing the future likelihood of success. All three funds sold their entire stake in the company. This is not always the case after a clinical failure. There are many cases where institutional investors increase their stake at a low price. Three institutional investors selling their entire stake strongly suggests these professionals do not see a bright future. For an unprofitable biotech company, institutional investors are an important source of capital. Funding an unprofitable biotech in the capital markets is very challenging currently. It is not clear Forte will be able to obtain future funding and if they do, terms will likely be unfavorable. What is clear is they have very limited cash ($38.5 m currently) and they will need hundreds of million to develop the new molecule. In fact, they have a shelf registration in place. Investors should expect substantial dilution. The Plan Forward The asset the company intends to move forward after the failure of FB-401 in atopic dermatitis is FB-102. Given this asset is in the very early stages of testing, prudence dictates an assessment as to whether the risk is worth the potential reward. This molecule may enter the clinic for testing as late as 2024. The company's presentation noted development plans in graft versus host disease (GvHD), vitiligo and alopecia areata which represent combined markets of over $6 billion. Each indication will require separate clinical trials to prove safety and efficacy adding substantially to the cost of development. Each of these indications has standard of care treatments. The company notes an unmet medical need. GvHD is a disease where there is a legitimate unmet need but there are other companies much further along in testing including Seres Therapeutics (MCRB) and MaaT Pharma. The unmet need may be satisfied by these entrants and MaaT has already produced favorable safety and efficacy data. Alopecia and vitiligo have very effective treatments currently-JAK inhibitors. The company noted the safety profile of JAK inhibitors. Opzelura is a topical JAK and most Doctors consider the safety profile of the cream to be of no concern whatsoever. In alopecia, where oral JAKS are approved, the safety and efficacy data for all 3 JAK inhibitors (Pfizer, Lilly and Concert) has been favorable but there is a black box warning. From an efficacy standpoint, there is no unmet need. From a safety standpoint, the mechanism of action and side effect profile are related. The JAK inhibitors work in vitiligo and alopecia areata by suppressing the immune system. There is nothing to suggest FB-102 can achieve the suppression of the immune system required for efficacy without the same safety issues. Investors are going to spend hundreds of million dollars developing treatments in indications where there are either treatments approved or assets years ahead of Forte's molecule, FB-102. Investors are taking on a huge amount of risk to enter crowded markets with little assurance of any competitive advantage. Of course, there is also the possibility the molecule does not show efficacy or adequate safety and needs to abandoned leaving Forte with no assets. To make development of FB-102 worthwhile, it would have to offer a benefit over existing treatments. The company presentation does not include the mechanism of action of FB-102 making it impossible to ascertain whether the "proprietary molecule" that involves "antagonism of a pathway for autoimmune disease" has any advantages or is even likely to work. The company cites infrequent dosing as a potential benefit of the treatment. This is an extraordinarily poor reason to spend hundreds of millions to develop a treatment. Dosing is a very unimportant issue in diseases such as GvHD which can be fatal. Vitiligo and alopecia areata are diseases where patients have skin discolorations or baldness and patients are highly motivated to take their medicine.Seeking Alpha • Jul 07Forte Biosciences large shareholders make demands for company's futureA pair of large shareholders of Forte Biosciences (NASDAQ:FBRX) are making demands that could impact the company's future, including the suggestion that the company liquidate. In a Wednesday SEC filing, Brad Leonard, managing member of BML Capital Management, which has a 9.1% stake in common shares, wrote that "Forte shareholders would be best served by a complete liquidation as soon as possible." Forte (FBRX) and some shareholders have been at odds over the future of Forte's only asset, FB-102, which is in the preclinical stage for several indications, including alopecia and vitiligo, a conditions that affects skin pigmentation. Leonard noted that since a May announcement on development plans, there has not been a single insider purchase. On Tuesday, Jacob Ma-Weaver, managing member of Funicular Funds, said in a SEC filing that Forte's board had yet to make an "adequate assessment of the potential immediate value creation that could be achieved through a substantial buyback program, tender offer at a premium, or special dividend." Funicular has a 7.5% stake. Seeking Alpha's Quant Rating views Forte (FBRX) as a hold with the only high grade being for valuation.Board Change • Apr 27High number of new and inexperienced directorsThere are 5 new directors who have joined the board in the last 3 years. The company's board is composed of: 5 new directors. 1 experienced director. No highly experienced directors. President, CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.Board Change • Apr 02High number of new and inexperienced directorsThere are 5 new directors who have joined the board in the last 3 years. The company's board is composed of: 5 new directors. 1 experienced director. No highly experienced directors. President, CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.分析記事 • Dec 23We Think Forte Biosciences (NASDAQ:FBRX) Needs To Drive Business Growth CarefullyThere's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...Board Change • Dec 05High number of new and inexperienced directorsThere are 4 new directors who have joined the board in the last 3 years. The company's board is composed of: 4 new directors. 1 experienced director. No highly experienced directors. President, CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The company’s lack of experienced directors is considered a risk according to the Simply Wall St Risk Model.Recent Insider Transactions • Sep 09President recently sold US$4.3m worth of stockOn the 7th of September, Paul A. Wagner sold around 1m shares on-market at roughly US$4.35 per share. This was the largest sale by an insider in the last 3 months. This was Paul A.'s only on-market trade for the last 12 months.Price Target Changed • Sep 04Price target increased to US$103Up from US$88.20, the current price target is an average from 5 analysts. New target price is 1,936% above last closing price of US$5.06. Stock is down 81% over the past year.Executive Departure • Jun 04Director Thomas Darcy has left the companyOn the 28th of May, Thomas Darcy's tenure as Director ended after 13.8 years in the role. As of March 2021, Thomas still personally held 25.14k shares (US$861k worth at the time). Thomas is the only executive to leave the company over the last 12 months. The current median tenure of the management team is less than a year, which is considered inexperienced in the Simply Wall St Risk Model.Breakeven Date Change • May 22Forecast to breakeven in 2025The 5 analysts covering Forte Biosciences expect the company to break even for the first time. New consensus forecast suggests the company will make a profit of US$49.1m in 2025. Average annual earnings growth of 44% is required to achieve expected profit on schedule.分析記事 • Mar 13Are Insiders Buying Forte Biosciences, Inc. (NASDAQ:FBRX) Stock?We often see insiders buying up shares in companies that perform well over the long term. The flip side of that is that...Is New 90 Day High Low • Feb 19New 90-day low: US$30.76The company is down 24% from its price of US$40.27 on 20 November 2020. The American market is up 10.0% over the last 90 days, indicating the company underperformed over that time. It also underperformed the Biotechs industry, which is up 15% over the same period.Is New 90 Day High Low • Jan 28New 90-day low: US$33.73The company is down 7.0% from its price of US$36.38 on 29 October 2020. The American market is up 21% over the last 90 days, indicating the company underperformed over that time. It also underperformed the Biotechs industry, which is up 28% over the same period.分析記事 • Jan 19Do Institutions Own Forte Biosciences, Inc. (NASDAQ:FBRX) Shares?A look at the shareholders of Forte Biosciences, Inc. ( NASDAQ:FBRX ) can tell us which group is most powerful...分析記事 • Nov 25Who Has Been Buying Forte Biosciences, Inc. (NASDAQ:FBRX) Shares?We've lost count of how many times insiders have accumulated shares in a company that goes on to improve markedly. The...Is New 90 Day High Low • Sep 29New 90-day high: US$50.69The company is up 232% from its price of US$15.25 on 01 July 2020. The American market is up 8.0% over the last 90 days, indicating the company outperformed over that time. It also outperformed the Biotechs industry, which is down 4.0% over the same period. According to the Simply Wall St valuation model, the estimated intrinsic value of the company is per share.株主還元FBRXUS BiotechsUS 市場7D39.8%-0.5%1.0%1Y697.1%31.0%19.1%株主還元を見る業界別リターン: FBRX過去 1 年間で31 % の収益を上げたUS Biotechs業界を上回りました。リターン対市場: FBRX過去 1 年間で19.1 % の収益を上げたUS市場を上回りました。価格変動Is FBRX's price volatile compared to industry and market?FBRX volatilityFBRX Average Weekly Movement27.3%Biotechs Industry Average Movement10.0%Market Average Movement7.2%10% most volatile stocks in US Market16.3%10% least volatile stocks in US Market3.2%安定した株価: FBRXの株価は、 US市場と比較して過去 3 か月間で変動しています。時間の経過による変動: FBRXの 週次ボラティリティ は、過去 1 年間で18%から27%に増加しました。会社概要設立従業員CEO（最高経営責任者ウェブサイトn/a22Paul A. Wagnerwww.fortebiorx.comフォルテ・バイオサイエンス社は、米国で臨床段階のバイオ医薬品会社として事業を展開している。同社の主力製品であるFB-102は、セリアック病、尋常性白斑、円形脱毛症、1型糖尿病などの自己免疫疾患および自己免疫関連疾患を適応症とする独自の抗CD122モノクローナル抗体治療薬候補である。フォルテ・バイオサイエンス社はテキサス州ダラスに本社を置いている。もっと見るForte Biosciences, Inc. 基礎のまとめForte Biosciences の収益と売上を時価総額と比較するとどうか。FBRX 基礎統計学時価総額US$1.88b収益（TTM）-US$75.85m売上高(TTM)n/a0.0xP/Sレシオ-24.7xPER（株価収益率FBRX は割高か？公正価値と評価分析を参照収益と収入最新の決算報告書（TTM）に基づく主な収益性統計FBRX 損益計算書（TTM）収益US$0売上原価US$0売上総利益US$0その他の費用US$75.86m収益-US$75.85m直近の収益報告Mar 31, 2026次回決算日該当なし一株当たり利益（EPS）-3.10グロス・マージン0.00%純利益率0.00%有利子負債／自己資本比率0%FBRX の長期的なパフォーマンスは？過去の実績と比較を見るView Valuation企業分析と財務データの現状データ最終更新日（UTC時間）企業分析2026/07/31 15:55終値2026/07/31 00:00収益2026/03/31年間収益2025/12/31データソース企業分析に使用したデータはS&P Global Market Intelligence LLC のものです。本レポートを作成するための分析モデルでは、以下のデータを使用しています。データは正規化されているため、ソースが利用可能になるまでに時間がかかる場合があります。パッケージデータタイムフレーム米国ソース例会社財務10年損益計算書キャッシュ・フロー計算書貸借対照表SECフォーム10-KSECフォーム10-Qアナリストのコンセンサス予想+プラス3年予想財務アナリストの目標株価アナリストリサーチレポートBlue Matrix市場価格30年株価配当、分割、措置ICEマーケットデータSECフォームS-1所有権10年トップ株主インサイダー取引SECフォーム4SECフォーム13Dマネジメント10年リーダーシップ・チーム取締役会SECフォーム10-KSECフォームDEF 14A主な進展10年会社からのお知らせSECフォーム8-K* 米国証券を対象とした例であり、非米国証券については、同等の規制書式および情報源を使用。特に断りのない限り、すべての財務データは1年ごとの期間に基づいていますが、四半期ごとに更新されます。これは、TTM（Trailing Twelve Month）またはLTM（Last Twelve Month）データとして知られています。詳細はこちら。分析モデルとスノーフレークこのレポートを生成するために使用した分析モデルの詳細は、当社のGitHubページでご覧いただけます。また、レポートの活用方法に関するガイドやYouTubeのチュートリアルも用意しています。シンプリー・ウォールストリート分析モデルを設計・構築した世界トップクラスのチームについてご紹介します。業界およびセクターの指標私たちの業界とセクションの指標は、Simply Wall Stによって6時間ごとに計算されます。アナリスト筋Forte Biosciences, Inc. 3 これらのアナリストのうち、弊社レポートのインプットとして使用した売上高または利益の予想を提出したのは、 。アナリストの投稿は一日中更新されます。10 アナリスト機関Etzer DaroutBarclaysKalpit PatelB. Riley Securities, Inc.Kumaraguru RajaBrookline Capital Markets7 その他のアナリストを表示
ライブニュース • Jul 29argenx to Acquire Forte Biosciences for $2.2 Billion in Immunology Dealargenx has agreed to acquire Forte Biosciences for about US$2.2 billion in total equity value, with the deal expected to close in the third quarter of 2026 subject to standard closing conditions. The acquisition is expected to bring Forte’s anti-CD122 antibody FB102 into argenx’s immunology portfolio. This transaction is material for Forte Biosciences because it effectively transfers FB102 to a larger immunology platform, which can influence how the asset is funded, developed and potentially commercialized. Forte Biosciences shares trade at US$76.53, with the stock up 259.0% over the past 30 days, reflecting a sharp repricing ahead of the proposed acquisition. The key focus now is deal risk. Investors will be watching regulatory approvals, timing to close and any potential shifts in terms, since the investment case largely hinges on the transaction completing as agreed.
Price Target Changed • Jul 27Price target increased by 12% to US$71.60Up from US$63.75, the current price target is an average from 5 analysts. New target price is 6.4% below last closing price of US$76.50. The company is forecast to post a net loss per share of US$3.97 next year compared to a net loss per share of US$4.71 last year.
お知らせ • Jul 27argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion.argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion on July 26, 2026. Under the terms of the offer, argenx SE will commence a cash tender offer to acquire all of the outstanding shares of Forte Biosciences’ common stock at a price of $77 in cash per share, representing a total equity value of approximately $2.2 billion. The transaction will be funded entirely from cash on hand. Following the successful completion of the tender offer, a wholly owned subsidiary of argenx will merge with Forte Biosciences and the outstanding Forte Biosciences shares not tendered in the tender offer will be converted into the right to receive the same $77 per share in cash paid in the tender offer. In case of termination of the transaction, seller will be required to pay argenx SE a termination fee of $65 million. The transaction is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of Forte Biosciences, and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act. The deal has been approved by the board of directors of argenx SE and Forte Biosciences, Inc. The acquisition is expected to close in Q3 2026. Goldman Sachs International acted as exclusive financial advisor to argenx SE. Damien Zoubek and Oliver J. Board of Freshfields US LLP acted as legal advisor to argenx SE. Guggenheim Securities, LLC acted as exclusive financial advisor to Forte Biosciences, Inc. Rob Ishii, Remi Korenblit, Dan Koeppen, Ben Capps, Rob Wernli, Megan Schilling, Brandon Gantus, Michael Hostetler, Minyoung Shin, Mark Bellomy, Joshua Gruenspecht, Anne Seymour, Eva Yin, Matthew Staples, Michael O'Brien, Myra Sutanto Shen, Jamillia Ferris, Michelle Yost Hale, and Deirdre Carroll of Wilson Sonsini Goodrich & Rosati, P.C. acted as legal advisor to Forte Biosciences, Inc. Computershare Trust Company, National Association acted as transfer agent for Forte Biosciences, Inc.
ライブニュース • Jul 12FB102 Achieves Primary Endpoint in Vitiligo Trial With Durable Improvement at Forte BiosciencesForte Biosciences reported that FB102 met its primary endpoint in a small placebo-controlled vitiligo trial, with statistically significant improvement in facial Vitiligo Area Scoring Index by week 24 and benefits persisting off treatment through week 24. Experts described the FB102 study as a success but highlighted the need for larger confirmatory trials to better quantify efficacy and fully characterize the safety profile. Forte Biosciences’ share price is at $43.92, with the stock up 150.1% over the past 30 days, reflecting a sharp recent repricing around the company’s prospects. The key question now is how future, larger FB102 studies read out, since the current data are early stage and come from a small sample, which can make the stock sensitive to any shift in efficacy or safety signals.
New Risk • Jul 09New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 25% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (25% average weekly change). Earnings are forecast to decline by an average of 30% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (100% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$189m net loss in 3 years).
お知らせ • Jul 09Forte Biosciences Announces Positive Results From FB102 Double-Blind Placebo-Controlled Phase 1b Study In VitiligoForte Biosciences, Inc. announced positive results from the FB102 double-blind placebo-controlled phase 1b study in vitiligo. FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvements observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 (p-value = 0.006) in subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), including: FVASI50 = 58.8%, FVASI75 = 23.5%. Responder endpoints in overall population achieved FVASI50 in 34.4% of FB102 treated subjects at week 24 with FVASI 75 achieved in 12.5% of FB102 treated subjects at week 24; this endpoint was impacted by one placebo FVASI75 responder, reinforcing the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. The majority of FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) of FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subjects worsened during the 24 week period. FB102 continues to demonstrate a strong safety profile and compared favorably to placebo with only mild to moderate AEs. These independent centrally-reviewed, placebo-controlled data demonstrate statistically significant FB102 mean FVASI improvements from baseline, with progressive improvement and a strong responder profile through week 24 after completion of the 12-week treatment period. The FB102 double-blind placebo-controlled phase 1b vitiligo study enrolled 43 subjects 3:1 randomized with 11 on placebo and 32 on FB102. Forte enrolled 2 FB102 treatment cohorts in the trial including the 3 mg/kg maintenance cohort previously disclosed. There were 15 on FB102 in Cohort A and 17 in Cohort B. The primary endpoint of the study was mean percent FVASI improvement from baseline assessed by central-review. The mean percent FVASI improvement from baseline in the ITT population was 29.6% for FB102 (n=32) compared to a mean deterioration of 16.2% for placebo (n=11), for a placebo-adjusted FB102 benefit of 45.8% (p=0.005). The group of 11 placebo subjects in the ITT population had one subject that was not part of the protocol-defined efficacy-evaluable population due to facial hair and that subject also experienced vitiligo progression during the study. The protocol defined efficacy-evaluable population excluded this one placebo subject (n=10) which also provides a more conservative assessment of the FB102 activity. In the protocol-defined efficacy evaluable population (FB102: 32, PBO:10), FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 vs 7.9% on placebo for a placebo-adjusted FB102 benefit of 21.7% (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvement observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. In Cohort A, FB102 achieved a 28.8% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 20.9% (p-value = 0.04) while in Cohort B, FB102 achieved a 30.4% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 22.5% (p-value = 0.027). In subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 compared to 0.5% for placebo treated subjects for a placebo-adjusted FB102 benefit of 42.7% (p-value = 0.006) with 10 of 17 FB102 treated subjects achieving an FVASI50 (58.8%) and 4 of 17 achieving an FVASI75 (23.5%) compared to 0 of 4 achieving FVASI50 and FVASI 75 for placebo subjects (0%). In the protocol-defined efficacy evaluable population 11 of 32 FB102 treated subjects achieved FVASI50 (34.4%) with 4 of 32 FB102 treated subjects achieving an FVASI 75 (12.5%) compared to 1 of 10 placebo subjects achieving FVASI50/75; the placebo FVASI75 responder reinforces the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subject worsened during the 24 week period. All AEs were mild/moderate with FB102 comparing favorably to placebo, and taken together with the phase1b celiac study, FB102 continues to demonstrate a strong safety profile.
ライブニュース • Jul 29argenx to Acquire Forte Biosciences for $2.2 Billion in Immunology Dealargenx has agreed to acquire Forte Biosciences for about US$2.2 billion in total equity value, with the deal expected to close in the third quarter of 2026 subject to standard closing conditions. The acquisition is expected to bring Forte’s anti-CD122 antibody FB102 into argenx’s immunology portfolio. This transaction is material for Forte Biosciences because it effectively transfers FB102 to a larger immunology platform, which can influence how the asset is funded, developed and potentially commercialized. Forte Biosciences shares trade at US$76.53, with the stock up 259.0% over the past 30 days, reflecting a sharp repricing ahead of the proposed acquisition. The key focus now is deal risk. Investors will be watching regulatory approvals, timing to close and any potential shifts in terms, since the investment case largely hinges on the transaction completing as agreed.
Price Target Changed • Jul 27Price target increased by 12% to US$71.60Up from US$63.75, the current price target is an average from 5 analysts. New target price is 6.4% below last closing price of US$76.50. The company is forecast to post a net loss per share of US$3.97 next year compared to a net loss per share of US$4.71 last year.
お知らせ • Jul 27argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion.argenx SE (ENXTBR:ARGX) entered into a definitive agreement to acquire Forte Biosciences, Inc. (NasdaqCM:FBRX) for $1.6 billion on July 26, 2026. Under the terms of the offer, argenx SE will commence a cash tender offer to acquire all of the outstanding shares of Forte Biosciences’ common stock at a price of $77 in cash per share, representing a total equity value of approximately $2.2 billion. The transaction will be funded entirely from cash on hand. Following the successful completion of the tender offer, a wholly owned subsidiary of argenx will merge with Forte Biosciences and the outstanding Forte Biosciences shares not tendered in the tender offer will be converted into the right to receive the same $77 per share in cash paid in the tender offer. In case of termination of the transaction, seller will be required to pay argenx SE a termination fee of $65 million. The transaction is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of Forte Biosciences, and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act. The deal has been approved by the board of directors of argenx SE and Forte Biosciences, Inc. The acquisition is expected to close in Q3 2026. Goldman Sachs International acted as exclusive financial advisor to argenx SE. Damien Zoubek and Oliver J. Board of Freshfields US LLP acted as legal advisor to argenx SE. Guggenheim Securities, LLC acted as exclusive financial advisor to Forte Biosciences, Inc. Rob Ishii, Remi Korenblit, Dan Koeppen, Ben Capps, Rob Wernli, Megan Schilling, Brandon Gantus, Michael Hostetler, Minyoung Shin, Mark Bellomy, Joshua Gruenspecht, Anne Seymour, Eva Yin, Matthew Staples, Michael O'Brien, Myra Sutanto Shen, Jamillia Ferris, Michelle Yost Hale, and Deirdre Carroll of Wilson Sonsini Goodrich & Rosati, P.C. acted as legal advisor to Forte Biosciences, Inc. Computershare Trust Company, National Association acted as transfer agent for Forte Biosciences, Inc.
ライブニュース • Jul 12FB102 Achieves Primary Endpoint in Vitiligo Trial With Durable Improvement at Forte BiosciencesForte Biosciences reported that FB102 met its primary endpoint in a small placebo-controlled vitiligo trial, with statistically significant improvement in facial Vitiligo Area Scoring Index by week 24 and benefits persisting off treatment through week 24. Experts described the FB102 study as a success but highlighted the need for larger confirmatory trials to better quantify efficacy and fully characterize the safety profile. Forte Biosciences’ share price is at $43.92, with the stock up 150.1% over the past 30 days, reflecting a sharp recent repricing around the company’s prospects. The key question now is how future, larger FB102 studies read out, since the current data are early stage and come from a small sample, which can make the stock sensitive to any shift in efficacy or safety signals.
New Risk • Jul 09New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 25% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (25% average weekly change). Earnings are forecast to decline by an average of 30% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (100% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$189m net loss in 3 years).
お知らせ • Jul 09Forte Biosciences Announces Positive Results From FB102 Double-Blind Placebo-Controlled Phase 1b Study In VitiligoForte Biosciences, Inc. announced positive results from the FB102 double-blind placebo-controlled phase 1b study in vitiligo. FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvements observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 (p-value = 0.006) in subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), including: FVASI50 = 58.8%, FVASI75 = 23.5%. Responder endpoints in overall population achieved FVASI50 in 34.4% of FB102 treated subjects at week 24 with FVASI 75 achieved in 12.5% of FB102 treated subjects at week 24; this endpoint was impacted by one placebo FVASI75 responder, reinforcing the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. The majority of FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) of FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subjects worsened during the 24 week period. FB102 continues to demonstrate a strong safety profile and compared favorably to placebo with only mild to moderate AEs. These independent centrally-reviewed, placebo-controlled data demonstrate statistically significant FB102 mean FVASI improvements from baseline, with progressive improvement and a strong responder profile through week 24 after completion of the 12-week treatment period. The FB102 double-blind placebo-controlled phase 1b vitiligo study enrolled 43 subjects 3:1 randomized with 11 on placebo and 32 on FB102. Forte enrolled 2 FB102 treatment cohorts in the trial including the 3 mg/kg maintenance cohort previously disclosed. There were 15 on FB102 in Cohort A and 17 in Cohort B. The primary endpoint of the study was mean percent FVASI improvement from baseline assessed by central-review. The mean percent FVASI improvement from baseline in the ITT population was 29.6% for FB102 (n=32) compared to a mean deterioration of 16.2% for placebo (n=11), for a placebo-adjusted FB102 benefit of 45.8% (p=0.005). The group of 11 placebo subjects in the ITT population had one subject that was not part of the protocol-defined efficacy-evaluable population due to facial hair and that subject also experienced vitiligo progression during the study. The protocol defined efficacy-evaluable population excluded this one placebo subject (n=10) which also provides a more conservative assessment of the FB102 activity. In the protocol-defined efficacy evaluable population (FB102: 32, PBO:10), FB102 achieved 29.6% mean FVASI improvement from baseline at week 24 vs 7.9% on placebo for a placebo-adjusted FB102 benefit of 21.7% (p-value = 0.020). Response to FB102 was observed early, with statistically significant improvement observed by the day 64 visit (p=0.023), continuing through week 24, after completion of the 12-week treatment period. In Cohort A, FB102 achieved a 28.8% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 20.9% (p-value = 0.04) while in Cohort B, FB102 achieved a 30.4% mean FVASI improvement from baseline at week 24 compared to 7.9% for placebo for a placebo-adjusted FB102 benefit of 22.5% (p-value = 0.027). In subjects with greater disease involvement having baseline FVASI =0.75 (approximately one-quarter of face depigmented), FB102 achieved 43.2% mean FVASI improvement from baseline at week 24 compared to 0.5% for placebo treated subjects for a placebo-adjusted FB102 benefit of 42.7% (p-value = 0.006) with 10 of 17 FB102 treated subjects achieving an FVASI50 (58.8%) and 4 of 17 achieving an FVASI75 (23.5%) compared to 0 of 4 achieving FVASI50 and FVASI 75 for placebo subjects (0%). In the protocol-defined efficacy evaluable population 11 of 32 FB102 treated subjects achieved FVASI50 (34.4%) with 4 of 32 FB102 treated subjects achieving an FVASI 75 (12.5%) compared to 1 of 10 placebo subjects achieving FVASI50/75; the placebo FVASI75 responder reinforces the importance of randomized controlled studies and baseline severity when interpreting vitiligo responder endpoints. FB102 treated subjects continued to improve through week 24 after completion of the 12-week treatment period with an additional 8 percentage point FVASI improvement between week 12 and 24. Among FB102-treated subjects with baseline FVASI =0.75 the mean FVASI improvement increased an additional 14 percentage points between week 12 and 24. 84% (27/32) FB102 treated subjects improved from baseline to week 24 following the 12-week treatment period and 0% (0/32) worsened. 27% (3/11) of placebo subject worsened during the 24 week period. All AEs were mild/moderate with FB102 comparing favorably to placebo, and taken together with the phase1b celiac study, FB102 continues to demonstrate a strong safety profile.
お知らせ • Jun 29+ 1 more updateForte Biosciences, Inc.(NasdaqCM:FBRX) dropped from Russell Microcap Value Benchmark IndexForte Biosciences, Inc.(NasdaqCM:FBRX) dropped from Russell Microcap Value Benchmark Index
お知らせ • May 02Forte Biosciences, Inc., Annual General Meeting, May 29, 2026Forte Biosciences, Inc., Annual General Meeting, May 29, 2026.
お知らせ • Apr 09+ 1 more updateForte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $150.000019 million.Forte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $150.000019 million. Security Name: Common Stock Security Type: Common Stock Securities Offered: 5,709,936 Price\Range: $26.27 Discount Per Security: $1.5762
Breakeven Date Change • Apr 02No longer forecast to breakevenThe 4 analysts covering Forte Biosciences no longer expect the company to break even during the foreseeable future. The company was expected to make a profit of US$133.6m in 2026. New consensus forecast suggests the company will make a loss of US$119.0m in 2027.
New Risk • Jan 13New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 17% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (17% average weekly change). Earnings are forecast to decline by an average of 30% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (179% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Currently unprofitable and not forecast to become profitable over next 3 years (US$161m net loss in 3 years).
Recent Insider Transactions • Jan 04Chief Financial Officer recently bought US$255k worth of stockOn the 30th of December, Antony Riley bought around 10k shares on-market at roughly US$26.33 per share. This transaction amounted to 30% of their direct individual holding at the time of the trade. This was the largest purchase by an insider in the last 3 months. This was Antony's only on-market trade for the last 12 months.
分析記事 • Nov 11We're Not Very Worried About Forte Biosciences' (NASDAQ:FBRX) Cash Burn RateWe can readily understand why investors are attracted to unprofitable companies. For example, Forte Biosciences...
お知らせ • Sep 16Forte Biosciences, Inc. Announces Presentation of Fb102 Celiac Disease Trial At Tampere Celiac Disease SymposiumForte Biosciences, Inc. announced additional details from the oral presentation "FB102 prevents histological damage and mitigates gluten challenge-induced symptoms in a celiac disease phase 1b study - Jason Tye-Din, Walter and Eliza Hall Institute; Royal Melbourne Hospital" at the Tampere Celiac Disease Symposium 2025 (Tampere, Finland) on September 12, 2025, further supporting the significant differentiation of FB102 in celiac disease. Highlights of the oral presentation include: FB102 demonstrated a decline in the TCR gd density from baseline of 1.5 compared to an increase of 3.9 for placebo (p=0.0007); TCR gd cells produce pro-inflammatory cytokines including IFN-g and TNF-a and upregulate activating receptors on epithelial cells triggering cytotoxic responses that directly kill the epithelial cells. Ki67-positive intraepithelial cell density increased from baseline by 8.6 on placebo compared to 2.5 on FB102 (p=0.0006); Ki67 is a marker of T cell proliferation (inflammation) on gluten exposure in celiac disease; NK cells declined by 95% following FB102 dosing; IL-15 upregulates activating receptors and confers resistance to activation-induced cell death and enhances T cell epithelial cytotoxicity in celiac disease; No statistically significant difference in Tregs between FB102 and placebo at any timepoint; Regulatory T cells (Tregs) help to modulate the immune response in autoimmune diseases like celiac disease. The phase 2 FB102 celiac disease trial is underway with topline data coming in 2026. The FB102 impact on the additional IEL subtypes in the phase 1b trial is extremely encouraging with respect to the additional therapeutic indications Forte is pursuing, including vitiligo and alopecia areata with data from both of these trials expected next year. In some cases, you can identify forward-looking statements by terms such as " may, "will," "should," "plan," "anticipate," "intend," target, project,contemplates," "bel believes,estimates," "predicts," "pot potential" or "continue" or the negatives of these terms or other similar statements are based on the Company's current beliefs and expectations. Forward-looking statements include statements regarding the Company's beliefs, goals, intentions and expectations regarding its product candidate, FB102 and the therapeutic and commercial market potential of FB102, expectations for patient enrollment and timing of clinical data readouts. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation: risks related to Forte's ability to obtain sufficient additional capital to continue to advance Forte's product candidate, FB102; uncertainties associated with the clinical development and regulatory approval of Forte's product candidate,FB102, including potential delays in the commencement, enrollment and completion of clinical trials, including the timing of the completion of the Company's patient-based trials; the risk that results from preclinical and any interim result of ongoing clinical trials may not be predictive of future results from clinical trials may not be predictive the failure to realize any value from FB102 in light of inherent risks, expense and difficulties involved in successfully bringing product candidates to market; and additional risks, uncertainties, and other information affecting Forte's business and operating results is contained in Forte's quarterly Report on Forms 10-QQQQQQQ.
Price Target Changed • Aug 18Price target increased by 14% to US$52.25Up from US$45.67, the current price target is an average from 4 analysts. New target price is 339% above last closing price of US$11.91. Stock is up 44% over the past year. The company is forecast to post a net loss per share of US$4.47 next year compared to a net loss per share of US$12.17 last year.
Price Target Changed • Aug 17Price target decreased by 8.2% to US$44.67Down from US$48.67, the current price target is an average from 3 analysts. New target price is 286% above last closing price of US$11.57. Stock is up 54% over the past year. The company is forecast to post a net loss per share of US$4.52 next year compared to a net loss per share of US$12.17 last year.
お知らせ • Jun 25+ 1 more updateForte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $75.000052 million.Forte Biosciences, Inc. has completed a Follow-on Equity Offering in the amount of $75.000052 million. Security Name: Common Stock Security Type: Common Stock Securities Offered: 5,630,450 Price\Range: $12 Discount Per Security: $0.72 Security Name: Pre-Funded Warrants Security Type: Equity Warrant Securities Offered: 619,606 Price\Range: $11.999 Discount Per Security: $0.72
お知らせ • Jun 24Forte Biosciences, Inc. Announces Positive Data in Ff102 Celiac Disease Phase 1B StudyForte Biosciences, Inc. announced positive data from a Phase 1b trial in celiac disease for lead program FB102 (FB102-101). Treatment emergent adverse events (TEAE) were primarily mild (grade 1) with no grade 3 or higher SAEs reported in the FB102 arm. Celiac disease is debilitating for many patients with even trace exposure to gluten. FB102 has taken a big step forward towards addressing this very large unmet need with the results from this study. The Phase 2 celiac disease study is initiating with a topline readout expected in 2026. These results are also very encouraging given the biology of the additional FB102 indications including vitiligo, alopecia areata and type 1 diabetes. The company also look forward to reading out the topline results of the FB102 vitiligo study in the first half of 2026.
New Risk • Jun 05New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$35m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$35m free cash flow). Share price has been highly volatile over the past 3 months (23% average weekly change). Shareholders have been substantially diluted in the past year (352% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Currently unprofitable and not forecast to become profitable next year (US$44m net loss next year). Market cap is less than US$100m (US$65.7m market cap).
お知らせ • Apr 21Forte Biosciences, Inc., Annual General Meeting, May 29, 2025Forte Biosciences, Inc., Annual General Meeting, May 29, 2025.
分析記事 • Apr 19We Think Forte Biosciences (NASDAQ:FBRX) Needs To Drive Business Growth CarefullyWe can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Price Target Changed • Apr 04Price target decreased by 45% to US$59.00Down from US$107, the current price target is an average from 2 analysts. New target price is 903% above last closing price of US$5.88. Stock is down 66% over the past year. The company is forecast to post a net loss per share of US$3.73 next year compared to a net loss per share of US$12.17 last year.
New Risk • Mar 24New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 18% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (18% average weekly change). Earnings are forecast to decline by an average of 26% per year for the foreseeable future. Shareholders have been substantially diluted in the past year (339% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$80m net loss in 3 years). Market cap is less than US$100m (US$52.2m market cap).
New Risk • Jan 13New major risk - Shareholder dilutionThe company's shareholders have been substantially diluted in the past year. Increase in shares outstanding: 340% This is considered a major risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Major Risks Share price has been highly volatile over the past 3 months (39% average weekly change). Earnings have declined by 3.9% per year over the past 5 years. Shareholders have been substantially diluted in the past year (340% increase in shares outstanding). Revenue is less than US$1m.
お知らせ • Nov 21Forte Biosciences, Inc. announced that it expects to receive $53 million in funding from OrbiMed Advisors LLC, Janus Henderson Group plc, Tybourne Capital Management Limited, Ikarian Capital, LLC, BVF Partners L.P., Fred Alger Management, LLCForte Biosciences, Inc. announced an private placement of common shares for gross proceeds of $53,000,000 on November 19, 2024. The transaction included participation from new and existing investors including OrbiMed Advisors LLC, Janus Henderson Group plc, Tybourne Capital Management Limited, Ikarian Capital, LLC, BVF Partners L.P., Red Hook Fund LP, Fred Alger Management, LLC. The Private Placement is expected to close on November 21, 2024.
Board Change • Oct 01High number of new directorsThere are 6 new directors who have joined the board in the last 3 years. Independent Director Rich Vincent was the last director to join the board, commencing their role in 2024. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.
Board Change • Sep 25High number of new directorsThere are 5 new directors who have joined the board in the last 3 years. Director Shivpreet Kapoor was the last director to join the board, commencing their role in 2024. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.
New Risk • Sep 19New major risk - Market cap sizeThe company's market capitalization is less than US$10m. Market cap: US$9.83m This is considered a major risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$31m free cash flow). Earnings have declined by 2.4% per year over the past 5 years. Revenue is less than US$1m. Market cap is less than US$10m (US$9.83m market cap). Minor Risk Share price has been volatile over the past 3 months (14% average weekly change).
New Risk • Aug 20New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 15% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$31m free cash flow). Share price has been highly volatile over the past 3 months (15% average weekly change). Earnings have declined by 2.4% per year over the past 5 years. Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$12.0m market cap).
Price Target Changed • Aug 16Price target increased by 25% to US$4.38Up from US$3.50, the current price target is an average from 2 analysts. New target price is 1,358% above last closing price of US$0.30. Stock is down 64% over the past year. The company posted a net loss per share of US$1.00 last year.
お知らせ • Jul 22Forte Biosciences, Inc., Annual General Meeting, Aug 20, 2024Forte Biosciences, Inc., Annual General Meeting, Aug 20, 2024.
分析記事 • Jul 17We're A Little Worried About Forte Biosciences' (NASDAQ:FBRX) Cash Burn RateThere's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
New Risk • Jun 28New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 9.8% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$30m free cash flow). Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Share price has been volatile over the past 3 months (9.8% average weekly change). Market cap is less than US$100m (US$17.5m market cap).
New Risk • May 15New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$30m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$30m free cash flow). Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$24.7m market cap).
分析記事 • Mar 14Is Forte Biosciences (NASDAQ:FBRX) In A Good Position To Deliver On Growth Plans?Just because a business does not make any money, does not mean that the stock will go down. For example, although...
New Risk • Nov 24New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 10% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$23m free cash flow). Earnings have declined by 4.6% per year over the past 5 years. Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risks Share price has been volatile over the past 3 months (10% average weekly change). Market cap is less than US$100m (US$15.6m market cap).
New Risk • Nov 16New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$16m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risks Less than 1 year of cash runway based on free cash flow trend (-US$16m free cash flow). Earnings have declined by 4.6% per year over the past 5 years. Shareholders have been substantially diluted in the past year (73% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$14.2m market cap).
Board Change • Oct 01High number of new directorsThere are 5 new directors who have joined the board in the last 3 years. Independent Director Mike Hacke was the last director to join the board, commencing their role in 2023. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.
お知らせ • Sep 22Forte Biosciences Receives Non-Compliance Letter from NasdaqOn September 14, 2023, Forte Biosciences, Inc. (the Company") received a written notice (the Notice") from the Nasdaq Listing Qualifications staff of The Nasdaq Stock Market LLC (Nasdaq") indicating that, for the last 30 consecutive business days, the minimum bid price of the Company's common stock had been below the $1.00 per share minimum requirement for continued listing on the Nasdaq Capital Market under Nasdaq Listing Rule 5550(a)(2) (the Minimum Bid Price Requirement"). In accordance with Nasdaq Listing Rule 5810(c)(3)(A), the Company has been provided an initial period of 180 calendar days, or until March 12, 2024, to regain compliance with the Minimum Bid Price Requirement. The Notice states that the Nasdaq staff will provide written notification that the Company has achieved compliance with Rule 5550(a)(2) if, at any time before March 12, 2024, the closing bid price of the Company's common stock is $1.00 per share or more for a minimum of ten consecutive business days. The Notice has no immediate effect on the listing or trading of the Company's common stock. In the event the Company does not regain compliance with the Minimum Bid Price Requirement by March 12, 2024, the Company may be eligible for additional time to regain compliance. To qualify, the Company will be required to meet the continued listing requirement for market value of publicly held shares and all other initial listing standards for The Nasdaq Capital Market, with the exception of the Minimum Bid Price Requirement, and will need to provide written notice of its intention to cure the deficiency during the second compliance period, by effecting a reverse stock split, if necessary. If the Company meets these requirements, the Company will be granted an additional 180 calendar days to regain compliance. If the Company does not qualify for or fails to regain compliance during the second compliance period, then the Nasdaq staff will provide written notification to the Company that its common stock will be subject to delisting. The Company would then be entitled to appeal that determination to a Nasdaq hearings panel. The Company intends to actively monitor the closing bid price of its common stock and consider its available options to regain compliance with the Minimum Bid Price Requirement. There can be no assurance that the Company will regain compliance with the Minimum Bid Price Requirement during the 180-day compliance period ending March 12, 2024, secure an extension of the compliance period beyond March 12, 2024 or maintain compliance with any other Nasdaq listing requirements.
お知らせ • Sep 21Forte Biosciences, Inc. Announces Directorate AppointmentsForte Biosciences, Inc. at its AGM held on September 19, 2023, approved appointment of Chris McIntyre and Michael G. Hacke as directors.
お知らせ • Sep 07Camac Partners Shares Key Facts that Reinforce the Need for Urgent Change in Forte Biosciences’s BoardroomOn September 6, 2023, Camac Partners, LLC and ATG Capital Management, LLC, the Group and its independent director candidates – Michael Hacke and Chris McIntyre – responded to misrepresentations and distortions included in Forte Biosciences, Inc’s recent presentation. Camac Partners stated that Hacke and McIntyre have been nominated by the Group for election to the Company’s Board of Directors at the upcoming Annual Meeting of Stockholders currently scheduled for September 19, 2023. Camac Partners stated that as a reminder, the Group recently filed its own presentation that details why it believes the Company is in urgent need of boardroom change following years of poor performance and worst-in-class governance under Chairman and CEO Paul Wagner. In addition, the Group encourages stockholders to consider the facts before deciding which individuals to support at the upcoming Annual Meeting.
お知らせ • Aug 26Forte Biosciences, Inc., Annual General Meeting, Sep 19, 2023Forte Biosciences, Inc., Annual General Meeting, Sep 19, 2023.
New Risk • Aug 18New major risk - Shareholder dilutionThe company's shareholders have been substantially diluted in the past year. Increase in shares outstanding: 78% This is considered a major risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Major Risks Earnings have declined by 2.6% per year over the past 5 years. Shareholders have been substantially diluted in the past year (78% increase in shares outstanding). Revenue is less than US$1m. Minor Risk Market cap is less than US$100m (US$30.3m market cap).
お知らせ • Jan 13Forte Biosciences, Inc appoints David Gryska to the Board of DirectorsForte Biosciences, Inc. announced that Mr. David Gryska has been appointed to the Forte Biosciences Board of Directors. Mr. Gryska was previously the Chief Financial Officer and Executive Vice President at Incyte. Prior to joining Incyte, Mr. Gryska held the position of Chief Financial Officer and Senior Vice President at Celgene prior to its acquisition by Bristol-Myers Squibb. Mr. Gryska has spent over 30 years as a senior executive at life science and biotechnology companies with extensive experience relating to strategic transactions, acquisitions, financings and global expansion.
Recent Insider Transactions • Dec 20CEO & Chairman recently bought US$105k worth of stockOn the 16th of December, Paul A. Wagner bought around 100k shares on-market at roughly US$1.05 per share. This transaction amounted to 7.8% of their direct individual holding at the time of the trade. This was the largest purchase by an insider in the last 3 months. This was Paul A.'s only on-market trade for the last 12 months.
Board Change • Nov 16High number of new and inexperienced directorsThere are 6 new directors who have joined the board in the last 3 years. The company's board is composed of: 6 new directors. 2 experienced directors. No highly experienced directors. CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.
Seeking Alpha • Aug 24Large Forte Biosciences shareholder scolds company board of directorsFunicular Funds, which owns 8% of the outstanding shares of Forte Biosciences (NASDAQ:FBRX), excoriated the company's board of directors in a letter over a recent capital raise. In an SEC filing, Funicular said the letter addressed the "Board’s failure to address the legitimate concerns previously raised by stockholders and its decision to embark on a value-destructive, scorched-earth path with a dilutive and unnecessary capital raise, without so much as an explanation for its actions." Funicular is asking to establish a committee of independent directors to investigate shareholder concerns. In July, a pair of large shareholders demanded changes at Forte (FBRX), including a suggestion that the company liquidate.
分析記事 • Aug 17We're Hopeful That Forte Biosciences (NASDAQ:FBRX) Will Use Its Cash WiselyThere's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Seeking Alpha • Aug 16Forte Biosciences: Lots Of Clinical Risk Ahead And A Questionable Business PlanFB-401, the lead asset failed in clinical trials. The company has one very early-stage asset they intend to move forward in the clinic, FB-102. Investors are likely to encounter dilution, a high degree of clinical risk and there is insufficient evidence to assess whether FB-401 has any advantages over other therapeutics. Summary Creativity is not my strength so I am reusing the title from an article that I wrote a few months back about Vyne Therapeutics, another dermatology company. The shares of Vyne have fallen 60% since then. The story is at Forte is essentially the same and all too common in biotech. Vyne and Forte both experienced setbacks, institutional investors sold and long term investors have fared poorly. Most importantly, for both companies, there is a suboptimal plan to move forward that exposes investors to a high degree of clinical risk, requires hundreds of millions of capital and has a low chance of rewarding investors in a manner commensurate with this outsized risk. I will outline a few reasons I rate Forte Biosciences (FBRX) a SELL Institutional Investors Major institutional investors have sold and cut their losses. Forte Biosciences had an enviable roster of professional investors including BVF, Orbimed and Perceptive Advisors. These are seasoned investors with a staff of PhD/MDs who are highly capable of assessing the future likelihood of success. All three funds sold their entire stake in the company. This is not always the case after a clinical failure. There are many cases where institutional investors increase their stake at a low price. Three institutional investors selling their entire stake strongly suggests these professionals do not see a bright future. For an unprofitable biotech company, institutional investors are an important source of capital. Funding an unprofitable biotech in the capital markets is very challenging currently. It is not clear Forte will be able to obtain future funding and if they do, terms will likely be unfavorable. What is clear is they have very limited cash ($38.5 m currently) and they will need hundreds of million to develop the new molecule. In fact, they have a shelf registration in place. Investors should expect substantial dilution. The Plan Forward The asset the company intends to move forward after the failure of FB-401 in atopic dermatitis is FB-102. Given this asset is in the very early stages of testing, prudence dictates an assessment as to whether the risk is worth the potential reward. This molecule may enter the clinic for testing as late as 2024. The company's presentation noted development plans in graft versus host disease (GvHD), vitiligo and alopecia areata which represent combined markets of over $6 billion. Each indication will require separate clinical trials to prove safety and efficacy adding substantially to the cost of development. Each of these indications has standard of care treatments. The company notes an unmet medical need. GvHD is a disease where there is a legitimate unmet need but there are other companies much further along in testing including Seres Therapeutics (MCRB) and MaaT Pharma. The unmet need may be satisfied by these entrants and MaaT has already produced favorable safety and efficacy data. Alopecia and vitiligo have very effective treatments currently-JAK inhibitors. The company noted the safety profile of JAK inhibitors. Opzelura is a topical JAK and most Doctors consider the safety profile of the cream to be of no concern whatsoever. In alopecia, where oral JAKS are approved, the safety and efficacy data for all 3 JAK inhibitors (Pfizer, Lilly and Concert) has been favorable but there is a black box warning. From an efficacy standpoint, there is no unmet need. From a safety standpoint, the mechanism of action and side effect profile are related. The JAK inhibitors work in vitiligo and alopecia areata by suppressing the immune system. There is nothing to suggest FB-102 can achieve the suppression of the immune system required for efficacy without the same safety issues. Investors are going to spend hundreds of million dollars developing treatments in indications where there are either treatments approved or assets years ahead of Forte's molecule, FB-102. Investors are taking on a huge amount of risk to enter crowded markets with little assurance of any competitive advantage. Of course, there is also the possibility the molecule does not show efficacy or adequate safety and needs to abandoned leaving Forte with no assets. To make development of FB-102 worthwhile, it would have to offer a benefit over existing treatments. The company presentation does not include the mechanism of action of FB-102 making it impossible to ascertain whether the "proprietary molecule" that involves "antagonism of a pathway for autoimmune disease" has any advantages or is even likely to work. The company cites infrequent dosing as a potential benefit of the treatment. This is an extraordinarily poor reason to spend hundreds of millions to develop a treatment. Dosing is a very unimportant issue in diseases such as GvHD which can be fatal. Vitiligo and alopecia areata are diseases where patients have skin discolorations or baldness and patients are highly motivated to take their medicine.
Seeking Alpha • Jul 07Forte Biosciences large shareholders make demands for company's futureA pair of large shareholders of Forte Biosciences (NASDAQ:FBRX) are making demands that could impact the company's future, including the suggestion that the company liquidate. In a Wednesday SEC filing, Brad Leonard, managing member of BML Capital Management, which has a 9.1% stake in common shares, wrote that "Forte shareholders would be best served by a complete liquidation as soon as possible." Forte (FBRX) and some shareholders have been at odds over the future of Forte's only asset, FB-102, which is in the preclinical stage for several indications, including alopecia and vitiligo, a conditions that affects skin pigmentation. Leonard noted that since a May announcement on development plans, there has not been a single insider purchase. On Tuesday, Jacob Ma-Weaver, managing member of Funicular Funds, said in a SEC filing that Forte's board had yet to make an "adequate assessment of the potential immediate value creation that could be achieved through a substantial buyback program, tender offer at a premium, or special dividend." Funicular has a 7.5% stake. Seeking Alpha's Quant Rating views Forte (FBRX) as a hold with the only high grade being for valuation.
Board Change • Apr 27High number of new and inexperienced directorsThere are 5 new directors who have joined the board in the last 3 years. The company's board is composed of: 5 new directors. 1 experienced director. No highly experienced directors. President, CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.
Board Change • Apr 02High number of new and inexperienced directorsThere are 5 new directors who have joined the board in the last 3 years. The company's board is composed of: 5 new directors. 1 experienced director. No highly experienced directors. President, CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The following issues are considered to be risks according to the Simply Wall St Risk Model: Lack of board continuity. Lack of experienced directors.
分析記事 • Dec 23We Think Forte Biosciences (NASDAQ:FBRX) Needs To Drive Business Growth CarefullyThere's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Board Change • Dec 05High number of new and inexperienced directorsThere are 4 new directors who have joined the board in the last 3 years. The company's board is composed of: 4 new directors. 1 experienced director. No highly experienced directors. President, CEO & Chairman Paul A. Wagner is the most experienced director on the board, commencing their role in 2017. The company’s lack of experienced directors is considered a risk according to the Simply Wall St Risk Model.
Recent Insider Transactions • Sep 09President recently sold US$4.3m worth of stockOn the 7th of September, Paul A. Wagner sold around 1m shares on-market at roughly US$4.35 per share. This was the largest sale by an insider in the last 3 months. This was Paul A.'s only on-market trade for the last 12 months.
Price Target Changed • Sep 04Price target increased to US$103Up from US$88.20, the current price target is an average from 5 analysts. New target price is 1,936% above last closing price of US$5.06. Stock is down 81% over the past year.
Executive Departure • Jun 04Director Thomas Darcy has left the companyOn the 28th of May, Thomas Darcy's tenure as Director ended after 13.8 years in the role. As of March 2021, Thomas still personally held 25.14k shares (US$861k worth at the time). Thomas is the only executive to leave the company over the last 12 months. The current median tenure of the management team is less than a year, which is considered inexperienced in the Simply Wall St Risk Model.
Breakeven Date Change • May 22Forecast to breakeven in 2025The 5 analysts covering Forte Biosciences expect the company to break even for the first time. New consensus forecast suggests the company will make a profit of US$49.1m in 2025. Average annual earnings growth of 44% is required to achieve expected profit on schedule.
分析記事 • Mar 13Are Insiders Buying Forte Biosciences, Inc. (NASDAQ:FBRX) Stock?We often see insiders buying up shares in companies that perform well over the long term. The flip side of that is that...
Is New 90 Day High Low • Feb 19New 90-day low: US$30.76The company is down 24% from its price of US$40.27 on 20 November 2020. The American market is up 10.0% over the last 90 days, indicating the company underperformed over that time. It also underperformed the Biotechs industry, which is up 15% over the same period.
Is New 90 Day High Low • Jan 28New 90-day low: US$33.73The company is down 7.0% from its price of US$36.38 on 29 October 2020. The American market is up 21% over the last 90 days, indicating the company underperformed over that time. It also underperformed the Biotechs industry, which is up 28% over the same period.
分析記事 • Jan 19Do Institutions Own Forte Biosciences, Inc. (NASDAQ:FBRX) Shares?A look at the shareholders of Forte Biosciences, Inc. ( NASDAQ:FBRX ) can tell us which group is most powerful...
分析記事 • Nov 25Who Has Been Buying Forte Biosciences, Inc. (NASDAQ:FBRX) Shares?We've lost count of how many times insiders have accumulated shares in a company that goes on to improve markedly. The...
Is New 90 Day High Low • Sep 29New 90-day high: US$50.69The company is up 232% from its price of US$15.25 on 01 July 2020. The American market is up 8.0% over the last 90 days, indicating the company outperformed over that time. It also outperformed the Biotechs industry, which is down 4.0% over the same period. According to the Simply Wall St valuation model, the estimated intrinsic value of the company is per share.
