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Annovis Bio, Inc.NYSE:ANVS Rapporto sulle azioni

Cap. di mercato US$94.9m
Prezzo delle azioni
US$2.01
US$12.5
83.9% sottovalutato sconto intrinseco
1Y1.0%
7D6.2%
1D
Valore del portafoglio
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Annovis Bio, Inc.

Report azionario NYSE:ANVS

Capitalizzazione di mercato: US$94.9m

Annovis Bio (ANVS) Panoramica del titolo

Annovis Bio, Inc. è una società di piattaforma farmacologica in fase clinica che sviluppa farmaci per il trattamento della neurodegenerazione negli Stati Uniti. Maggiori dettagli

ANVS analisi fondamentale
Punteggio fiocco di neve
Valutazione2/6
Crescita futura0/6
Prestazioni passate0/6
Salute finanziaria6/6
Dividendi0/6

Premi

Negoziato a 99.8% al di sotto della nostra stima del suo valore equo

Analisi del rischio

Gli azionisti sono stati sostanzialmente diluiti nell'ultimo anno

Realizza un fatturato inferiore a 1 milione di dollari ( $0 )

Prezzo delle azioni volatile negli ultimi 3 mesi rispetto al mercato US

Attualmente non redditizio e non si prevede che diventerà redditizio nei prossimi 3 anni

+ 1 più rischio

ANVS Community Fair Values

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Concorrenti di Annovis Bio, Inc.

Storia dei prezzi e prestazioni

Riepilogo dei massimi, dei minimi e delle variazioni dei prezzi delle azioni per Annovis Bio
Prezzi storici delle azioni
Prezzo attuale dell'azioneUS$2.06
Massimo di 52 settimaneUS$5.50
Minimo di 52 settimaneUS$1.54
Beta1.26
Variazione di 1 mese18.39%
Variazione a 3 mesi-28.47%
Variazione di 1 anno0.98%
Variazione a 3 anni-83.80%
Variazione a 5 anni-96.42%
Variazione dall'IPO-78.52%

Notizie e aggiornamenti recenti

Articolo di analisi • May 22

3 Parkinson's Biotech Stocks Analysts Think Are Wildly Mispriced

Most biotech stocks working towards a treatment for Parkinson's are already carrying a premium price. These three sit further off the radar, and analysts think the market has them badly wrong.

Recent updates

Articolo di analisi • May 22

3 Parkinson's Biotech Stocks Analysts Think Are Wildly Mispriced

Most biotech stocks working towards a treatment for Parkinson's are already carrying a premium price. These three sit further off the radar, and analysts think the market has them badly wrong.
Articolo di analisi • Jun 25

We Think Annovis Bio (NYSE:ANVS) Needs To Drive Business Growth Carefully

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Articolo di analisi • Dec 06

We're A Little Worried About Annovis Bio's (NYSE:ANVS) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Seeking Alpha • Oct 17

Annovis Bio To Continue Alzheimer's Disease Clinical Trials

Summary In April 2024, Annovis Bio's lead drug, Buntanetap, failed to show efficacy in its phase 2/3 Alzheimer's Disease trial, leading to a 70% stock drop. The company plans to proceed with a phase 3 trial despite the lack of convincing efficacy data and significant financial constraints. Annovis has limited cash reserves and faces challenges in financing further trials, making the future of Buntanetap uncertain. Read the full article on Seeking Alpha
Seeking Alpha • Sep 27

Annovis Bio: Progress With Buntanetap In Parkinson's Disease, But Cash Runway Concerns Loom

Summary Annovis Bio's Buntanetap shows promising results in treating Alzheimer's and Parkinson's, with significant cognitive and motor function improvements in Phase 2/3 and Phase 3 trials. The drug also improved motor function in Phase 3 Parkinson’s trials, especially in advanced cases and PIGD patients. Buntanetap's mechanism of action targets neurotoxic proteins, offering symptomatic and possibly disease-modifying benefits, making it a valuable IP for combination therapies. Buntanetap showed statistically significant cognitive improvement in Phase 2/3 Alzheimer’s trials, particularly at 15mg and 30mg doses. Unfortunately, its short cash runway can't be ignored. So, I maintain a "hold" rating on ANVS until it secures more long-term financing. Read the full article on Seeking Alpha
Seeking Alpha • Jul 08

Annovis Bio Rallies On Missed ITT Parkinson's Study Endpoints

Summary Analysis of Annovis Bio's lead product, buntanetap, tested in neurodegenerative diseases suggests questionable efficacy, in our opinion. Recent topline data from the PD phase 3 study shows no efficacy in the ITT population among positive post-hoc claims. The company intends to meet with the FDA and discuss an NDA filing, which, we believe, is currently not supported by the available evidence. Financial constraints persist, with ~$4M cash left on the balance sheet. Read the full article on Seeking Alpha
Seeking Alpha • Jun 30

Annovis: Strong Sell Reiteration Prior To Phase 3 Data In Parkinson's Disease

Summary Annovis Bio's only potential catalyst is the upcoming Phase 3 readout for Parkinson's disease. The company's changes to the primary endpoints of that trial, contrary to the FDA's wishes, cause concern. There is now more certainty that the Phase 2/3 trial in Alzheimer's disease failed to reach its primary endpoints. A recent CFO resignation, lack of funding and the company's wishes to conduct large further trials lead to a Strong Sell rating. Read the full article on Seeking Alpha
Seeking Alpha • May 02

Annovis Bio: Alzheimer's Phase 2/3 Topline Readout Puts Future For Buntanetap Into Question

Summary Annovis reported topline data from a Phase 2/3 trial in Alzheimer's disease, but the trial was a failure. The exclusion of 37% of the patient population and the focus on mild AD patients were not pre-specified, raising concerns. Annovis faces financial challenges and may see a significant decline in stock prices. Read the full article on Seeking Alpha
Seeking Alpha • Feb 12

Annovis: Potentially Encouraging Anecdotes, Weighing Phase 3 Parkinson's Prospects

Summary A small sample of patient anecdotes on the internet suggest that buntanetap has some degree of underlying activity in Parkinson’s disease (PD). 24-38% of patient anecdotes report a noticeable/measurable improvement in Parkinson’s symptoms, which could suggest that a majority of patients in the higher 20 mg (higher dose) cohort experienced an improvement. A positive topline readout for the buntanetap 20mg dose would have a positive readthrough to the Alzheimer’s results due in 2Q24. The company has the overhang of needing to raise cash imminently and faces general market skepticism. Read the full article on Seeking Alpha
Seeking Alpha • Jan 30

Annovis And Alzheimer's Disease: The Best-Laid Plans

Summary Annovis will likely announce results from it Parkinson's disease and Alzheimer's disease trials in the next couple of month. Annovis inhibits the formation of the amyloid precursor protein. The primary triggers for Alzheimer's disease are unrelated to amyloid, making it unlikely that Annovis' buntanetap will substantially impact disease progression. Anti-amyloid drugs only slow down the progression of Alzheimer's disease in its early stages in APOE4 carriers and may not be effective in the long-term. Read the full article on Seeking Alpha
Seeking Alpha • Jan 20

Annovis Bio: Buntanetap Likely To Disappoint In The Upcoming AD And PD Clinical Trials

Summary Annovis Bio has two upcoming major catalysts, a phase 2/3 AD clinical trial and a phase 3 PD clinical trial. The investigational drug, Buntanetap, is an enantiomer of a molecule previously tested for AD, with no success. We believe that the likelihood of success for Buntanetap in clinical trials is low, and if the drug fails, Annovis Bio's stock could plummet to or below its cash reserves. Read the full article on Seeking Alpha
Seeking Alpha • Oct 16

Annovis: Due Diligence Prior To Parkinson's And Alzheimer's Readouts

Summary Annovis is expected to report data from Phase 3 and Phase 2/3 trials in Parkinson's and Alzheimer's disease, respectively. The efficacy of Annovis' lead compound, Buntanetap, is difficult to align with its proposed disease-modifying mechanism of action. Annovis has a low market cap and may need to raise capital around the upcoming topline data. Given previously seen stock volatility, I believe a good understanding of the upcoming reporting is in place. Read the full article on Seeking Alpha
Articolo di analisi • Sep 08

Annovis Bio (NYSE:ANVS) Will Have To Spend Its Cash Wisely

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha • Jun 28

Annovis Bio: End Of 2023 Parkinson's Data Could Shift Momentum

Summary Results from the phase 3 study, using buntanetap for the treatment of patients with Parkinson's Disease, are expected to be released before the end of 2023. The global Parkinson's Disease drug market is expected to reach $10.4 billion by 2031. Buntanetap is also being explored in an ongoing phase 2/3 study for the treatment of patients with mild to moderate Alzheimer's Disease. Annovis Bio had $16.8 million in cash as of March 31, 2023; enough cash to fund its operations into Q1 of 2024 and will likely need to raise additional cash before end of 2023. Read the full article on Seeking Alpha
Seeking Alpha • Feb 08

Annovis wins EU nod to expand late-stage trial for Parkinson's candidate

Annovis Bio (NYSE:ANVS) announced Wednesday the EU approval to bring additional 48 trial sites for its Phase 3 study for lead candidate buntanetap in the treatment of Parkinson's disease ("PD"). With 50 clinical trial sites open in the U.S., the clinical-stage biotech is currently enrolling patients for the randomized study, which tests buntanetap 10mg or 20mg vs. placebo in addition to standard of care for six months. "We are pleased to significantly expand our geographic reach with the addition of these EU sites that gives us the ability to efficiently enroll European patients in our study," Chief Executive of Annovis (ANVS) Maria Maccecchini remarked. The company intends to enroll early PD patients in these additional trial sites, spread across countries such as Italy, Spain, Hungary, Poland, and Germany. An interim readout is expected in Q2 2023 if there is a sufficient number of patients who have received two months of therapy. Seeking Alpha contributor Terry Chrisomalis issued a Strong Buy rating on Annovis (ANVS) last year, citing the potential of buntanetap in PD.
Articolo di analisi • Jan 28

We Think Annovis Bio (NYSE:ANVS) Can Afford To Drive Business Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha • Jan 25

Annovis gains amid ‘strong’ enrollment in late-stage trial Parkinson's drug

Clinical stage biotech Annovis Bio (NYSE:ANVS) traded higher in the morning hours Wednesday after the company highlighted "strong" patient enrollment in its Phase 3 trial for Parkinson's disease (PD) candidate buntanetap. "We are very pleased with the pace of enrollment in our Phase 3 study, designed to assess the safety and efficacy of buntanetap in early-stage Parkinson's patients," Chief Executive Maria Maccecchini noted. The company has arranged an interim data analysis in Q2 2023 to see if its original target of 150 patients per arm will be enough to demonstrate a treatment effect. "Based on the current enrollment, the Company anticipates having a sufficient number of patients who have received two months of therapy to conduct an interim analysis in the second quarter of 2023," Annovis (ANVS) added. Buntanetap, formerly known as ANVS401 or Posiphen, has potential not only in PD but also in Alzheimer's, Seeking Alpha contributor Terry Chrisomalis points out.
Seeking Alpha • Oct 06

Annovis: Late-Stage Parkinson's Disease Trial Advancement Makes It Worth A Look

Summary Green light received from the FDA to initiate a phase 3 study using buntanetap for the treatment of early-stage Parkinson's Disease patients. The global Parkinson's Disease market is expected to reach $8.38 billion by end of 2026. Potential to receive clearance to initiate a phase 3 study using buntanetap for the treatment of patients with Alzheimer's Disease if end of phase 2 meeting goes well. Other drugs in the pipeline include ANVS301 for advanced Alzheimer's Disease/dementia and ANVS405 for traumatic brain injury and stroke.
Articolo di analisi • Sep 15

We're Hopeful That Annovis Bio (NYSE:ANVS) Will Use Its Cash Wisely

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...

Rendimenti per gli azionisti

ANVSUS BiotechsUS Mercato
7D6.2%2.9%2.5%
1Y1.0%33.0%26.4%

Ritorno vs Industria: ANVS ha avuto una performance inferiore rispetto al US Biotechs che ha registrato un rendimento 33 % nell'ultimo anno.

Rendimento vs Mercato: ANVS ha avuto una performance inferiore al mercato US che ha registrato un rendimento 26.4 % nell'ultimo anno.

Volatilità dei prezzi

Is ANVS's price volatile compared to industry and market?
ANVS volatility
ANVS Average Weekly Movement14.2%
Biotechs Industry Average Movement10.8%
Market Average Movement7.2%
10% most volatile stocks in US Market16.5%
10% least volatile stocks in US Market3.1%

Prezzo delle azioni stabile: Negli ultimi 3 mesi il prezzo delle azioni di ANVS è stato volatile rispetto al mercato US.

Volatilità nel tempo: La volatilità settimanale ( 14% ) di ANVS è rimasta stabile nell'ultimo anno, ma è comunque superiore al 75% delle azioni US.

Informazioni sull'azienda

FondatoI dipendentiAMMINISTRATORE DELEGATOSito web
20087Maria Maccecchiniwww.annovisbio.com

Annovis Bio, Inc. è una piattaforma farmaceutica in fase clinica che sviluppa farmaci per il trattamento della neurodegenerazione negli Stati Uniti. Il candidato principale dell'azienda è Buntanetap, in fase 3 per il trattamento della malattia di Alzheimer e in fase 3 in aperto per il trattamento della malattia di Parkinson. L'azienda sviluppa anche ANVS405, che è in fase 2 e 3 di sperimentazione clinica per il trattamento delle lesioni cerebrali traumatiche e/o dell'ictus, e ANVS301, che ha terminato la fase 1 di sperimentazione clinica per aumentare le capacità cognitive negli ultimi stadi della malattia di Alzheimer e della demenza.

Annovis Bio, Inc. Riepilogo dei fondamenti

Come si confrontano gli utili e i ricavi di Annovis Bio con la sua capitalizzazione di mercato?
ANVS statistiche fondamentali
Capitalizzazione di mercatoUS$94.87m
Utili (TTM)-US$40.92m
Ricavi(TTM)n/a
0.0x
Rapporto P/S
-2.1x
Rapporto P/E

ANVS è sopravvalutato?

Vedi Fair Value e analisi di valutazione

Utili e ricavi

Statistiche chiave sulla redditività dall'ultima relazione sugli utili (TTM)
ANVS Conto economico (TTM)
RicaviUS$0
Costo del fatturatoUS$0
Profitto lordoUS$0
Altre speseUS$40.92m
Utili-US$40.92m

Ultimi utili riportati

Mar 31, 2026

Prossima data di guadagno

n/a

Utile per azione (EPS)-0.96
Margine lordo0.00%
Margine di profitto netto0.00%
Rapporto debito/patrimonio netto0%

Come si è comportato ANVS nel lungo periodo?

Vedi performance storica e confronto

Analisi aziendale e situazione dei dati finanziari

DatiUltimo aggiornamento (ora UTC)
Analisi dell'azienda2026/05/26 18:19
Prezzo dell'azione a fine giornata2026/05/26 00:00
Utili2026/03/31
Utili annuali2025/12/31

Fonti dei dati

I dati utilizzati nella nostra analisi aziendale provengono da S&P Global Market Intelligence LLC. I seguenti dati sono utilizzati nel nostro modello di analisi per generare questo report. I dati sono normalizzati, il che può comportare un ritardo nella disponibilità della fonte.

PacchettoDatiTempisticaEsempio Fonte USA *
Dati finanziari della società10 anni
  • Conto economico
  • Rendiconto finanziario
  • Bilancio
Stime di consenso degli analisti+3 anni
  • Previsioni finanziarie
  • Obiettivi di prezzo degli analisti
Prezzi di mercato30 anni
  • Prezzi delle azioni
  • Dividendi, scissioni e azioni
Proprietà10 anni
  • Top azionisti
  • Insider trading
Gestione10 anni
  • Team di leadership
  • Consiglio di amministrazione
Sviluppi principali10 anni
  • Annunci aziendali

* Esempio per i titoli statunitensi, per i titoli non statunitensi si utilizzano forme e fonti normative equivalenti.

Se non specificato, tutti i dati finanziari si basano su un periodo annuale ma vengono aggiornati trimestralmente. Si tratta dei cosiddetti dati TTM (Trailing Twelve Month) o LTM (Last Twelve Month). Per saperne di più.

Modello di analisi e Snowflake

I dettagli del modello di analisi utilizzato per generare questo report sono disponibili sulla nostra pagina Github; abbiamo anche guide su come utilizzare i nostri report e tutorial su Youtube.

Scoprite il team di livello mondiale che ha progettato e realizzato il modello di analisi Simply Wall St.

Metriche di settore e industriali

Le nostre metriche di settore e di sezione sono calcolate ogni 6 ore da Simply Wall St; i dettagli del nostro processo sono disponibili su Github.

Fonti analitiche

Annovis Bio, Inc. è coperta da 3 analisti. 2 di questi analisti ha fornito le stime di fatturato o di utile utilizzate come input per il nostro report. Le stime degli analisti vengono aggiornate nel corso della giornata.

AnalistaIstituzione
Sumant Satchidanand KulkarniCanaccord Genuity
Jason KolbertD. Boral Capital LLC.
Jason McCarthyMaxim Group