U.S. Pharmaceuticals & Biotech Mid-Large Cap Stocks

PTC Therapeutics

Market Cap: US$4.7b

A biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to children and adults living with rare disorders in the United States and internationally.

Arcellx

Market Cap: US$4.4b

Together with its subsidiary, engages in the development of various immunotherapies for patients with cancer and other incurable diseases in the United States.

YD Bio

Market Cap: US$1.2b

A biopharmaceutical company focuses on blood-based cancer detection and develops stem cell- and exosome-based therapeutics to transform the treatment of spectrum of diseases with unmet medical needs.

Veracyte

Market Cap: US$2.6b

Operates as a diagnostics company in the United States and internationally.

West Pharmaceutical Services

Market Cap: US$18.7b

Designs, manufactures, and sells containment and delivery systems for injectable drugs and healthcare products in the Americas, Europe, the Middle East, Africa, and the Asia Pacific.

Maze Therapeutics

Market Cap: US$1.1b

A clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of renal, cardiovascular, related metabolic diseases, and obesity in the United States.

Indivior

Market Cap: US$2.9b

Develops, manufactures, and sells buprenorphine-based prescription drugs for the treatment of opioid dependence and related disorders in the United States, Europe, Canada, Australia, and internationally.

Mineralys Therapeutics

Market Cap: US$3.0b

A clinical-stage biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States.

Tarsus Pharmaceuticals

Market Cap: US$2.3b

A commercial stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for eye care in the United States.

Waters

Market Cap: US$17.4b

Provides analytical workflow solutions in Asia, the Americas, and Europe.

BGM Group

Market Cap: US$2.0b

Through its subsidiaries, operates as a pharmaceutical and chemical company in China.

Ionis Pharmaceuticals

Market Cap: US$10.2b

A commercial-stage biotechnology company, provides RNA-targeted medicines in the United States.

ImmunityBio

Market Cap: US$2.4b

A commercial stage biotechnology company, develops next-generation therapies that bolster the natural immune systems to defeat cancers and infectious diseases.

BioMarin Pharmaceutical

Market Cap: US$10.3b

A biotechnology company, engages in the development and commercialization of therapies for life-threatening rare diseases and medical conditions in the United States, Europe, Latin America, the Middle East, the Asia Pacific, and internationally.

Sierra Oncology

Market Cap: US$1.3b

Sierra Oncology, Inc., a late-stage biopharmaceutical company, engages in researching, developing, and commercializing therapies for the treatment of patients with hematology and oncology needs.

Ocular Therapeutix

Market Cap: US$2.2b

A biopharmaceutical company, engages in the development and commercialization of therapies for retinal diseases and other eye conditions using its bioresorbable hydrogel-based formulation technology in the United States.

ORIC Pharmaceuticals

Market Cap: US$1.0b

A clinical-stage biopharmaceutical company, engages in the discovery and development of therapies to counter the resistance mechanisms cancers in the United States.

Nuvalent

Market Cap: US$5.7b

A clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer.

Alvotech

Market Cap: US$2.7b

Through its subsidiaries, develops and manufactures biosimilar medicines for patients worldwide.

Agios Pharmaceuticals

Market Cap: US$2.2b

A biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States.

Apellis Pharmaceuticals

Market Cap: US$2.9b

A commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs.

10x Genomics

Market Cap: US$1.5b

A life science technology company, develops and sells instruments, consumables, and software for analyzing biological systems in the Americas, Europe, the Middle East, Africa, China, and the Asia Pacific.

Protagonist Therapeutics

Market Cap: US$4.1b

A biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases.

MannKind

Market Cap: US$1.6b

A biopharmaceutical company, focuses on the development and commercialization of therapeutic products and services for endocrine and orphan lung diseases in the United States.

Avadel Pharmaceuticals

Market Cap: US$1.5b

Operates as a biopharmaceutical company in the United States.

Legend Biotech

Market Cap: US$6.1b

Through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and commercializes novel cell therapies for oncology and other indications in the United States, China, and Europe.

Aurinia Pharmaceuticals

Market Cap: US$1.7b

A biopharmaceutical company that engages in delivering therapies to people living with autoimmune diseases with high unmet medical needs.

Natera

Market Cap: US$22.5b

A diagnostics company, provides molecular testing services worldwide.

Immunovant

Market Cap: US$2.7b

A clinical-stage immunology company, develops monoclonal antibodies for the treatment of autoimmune diseases.

Scholar Rock Holding

Market Cap: US$3.2b

A biopharmaceutical company, focuses on the discovery, development, and delivery of medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role.

Avidity Biosciences

Market Cap: US$6.2b

A biopharmaceutical company, engages in the delivery of RNA therapeutics called antibody oligonucleotide conjugates (AOCs).

Celcuity

Market Cap: US$2.3b

A clinical-stage biotechnology company, focuses on the development of targeted therapies for the treatment of various solid tumors in the United States.

Kymera Therapeutics

Market Cap: US$3.8b

A clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body’s own natural protein degradation system.

Verona Pharma

Market Cap: US$9.2b

A biopharmaceutical company, focuses on development and commercialization of therapies for the treatment of respiratory diseases with unmet medical needs.

Amneal Pharmaceuticals

Market Cap: US$3.0b

A global biopharmaceutical company, develops, manufactures, markets, and distributes generics, injectables, biosimilars, and specialty branded pharmaceutical products worldwide.

Crinetics Pharmaceuticals

Market Cap: US$3.3b

A clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors.