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Mereo BioPharma Group plcNasdaqCM:MREO Aktienübersicht

Marktkapitalisierung US$45.1m
Aktienkurs
US$0.27
US$1.75
84.4% unterbewertet intrinsischer Abschlag
1Y-88.1%
7D10.6%
1D
Wert des Portfolios
​
Siehe

Mereo BioPharma Group plc

NasdaqCM:MREO Lagerbericht

Marktkapitalisierung: US$45.1m

Mereo BioPharma Group (MREO) Aktienübersicht

Mereo BioPharma Group plc, ein biopharmazeutisches Unternehmen, entwickelt und vermarktet Therapeutika für die Behandlung seltener Krankheiten im Vereinigten Königreich und in den Vereinigten Staaten. Mehr Details

MREO grundlegende Analyse
Schneeflocken-Punktzahl
Bewertung1/6
Künftiges Wachstum3/6
Vergangene Leistung0/6
Finanzielle Gesundheit5/6
Dividenden0/6

Belohnungen

Prognostiziertes jährliches Umsatzwachstum 52.41%

Risikoanalyse

Erzielt weniger als 1 Million USD an Einnahmen ($500K)

Hat keine nennenswerte Marktkapitalisierung ($45M)

Derzeit unrentabel und in den nächsten 3 Jahren nicht rentabel zu werden prognostiziert


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Mereo BioPharma Group plc Wettbewerber

Preisentwicklung & Leistung

Zusammenfassung der Höchst- und Tiefststände sowie der Veränderungen der Aktienkurse für Mereo BioPharma Group
Historische Aktienkurse
Aktueller AktienkursUS$0.27
52-Wochen-HochUS$3.05
52-Wochen-TiefUS$0.20
Beta0.19
1 Monat Veränderung-16.02%
3 Monate Veränderung-35.81%
1 Jahr Veränderung-88.07%
3 Jahre Veränderung-74.33%
5 Jahre Veränderung-91.52%
Veränderung seit IPO-95.81%

Aktuelle Nachrichten und Updates

Analyseartikel • May 02

Here's Why We're Not Too Worried About Mereo BioPharma Group's (NASDAQ:MREO) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...

Recent updates

Analyseartikel • May 02

Here's Why We're Not Too Worried About Mereo BioPharma Group's (NASDAQ:MREO) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Analyseartikel • Sep 27

Here's Why We're Not At All Concerned With Mereo BioPharma Group's (NASDAQ:MREO) Cash Burn Situation

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analyseartikel • May 19

We're Not Very Worried About Mereo BioPharma Group's (NASDAQ:MREO) Cash Burn Rate

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analyseartikel • Apr 07

Is Mereo BioPharma Group (NASDAQ:MREO) Weighed On By Its Debt Load?

The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
Analyseartikel • Nov 25

Is Mereo BioPharma Group (NASDAQ:MREO) Using Debt Sensibly?

Warren Buffett famously said, 'Volatility is far from synonymous with risk.' So it seems the smart money knows that...
Seeking Alpha • Oct 17

Mereo stock rises 12% on FDA fast-track status for lung disease drug alvelestat

The U.S. Food and Drug Administration (FDA) granted fast track designation to Mereo BioPharma alvelestat (MPH-966) to treat Alpha-1 Antitrypsin Deficiency (AATD)-associated lung disease. The London-based company said it plans to have an end-of-phase 2 meeting with the FDA to discuss the design of a registration-enabling study for alvelestat for AATD-associated lung disease, including a potential opportunity for an accelerated approval pathway. AATD is a genetic disorder characterized by low levels of a protein called alpha-1 antitrypsin (A1AT). The disorder can cause pulmonary emphysema, a progressive lung disease, which can cause shortness of breath, chronic cough and asthma, according to the company. Mereo said it intends to provide update on Oct. 31 on a phase 2 trial called ASTRAEUS of alvelestat in severe AATD-associated emphysema — top-line data from which were reported in May. MREO +12.01% to $1.12 premarket Oct. 17
Seeking Alpha • Oct 03

Rubric Capital boosts Mereo BioPharma board nominees slate to five

Rubric Capital Management has boosted the number of nominees it is backing for Mereo BioPharma (NASDAQ:MREO) to five. The fifth nominee is Rubric founder David Rosen. In a letter to shareholders, Rosen wrote that "the problems on the Board of Mereo (MREO) run deeper than we anticipated." The letter also criticizes Mereo's (MREO) Board for rejecting "our request for a special meeting based on the flimsiest of pretexts." Rubric owns ~14% of the company's outstanding shares. The stock is up 4% in Monday afternoon trading. In September, Mereo (MREO) slammed Rubric for rejecting an offer to put a Rubric principal and another director on the company's board.
Seeking Alpha • Sep 22

Mereo BioPharma: An Activist Pressure With A Potentially Significant Upside

Summary This is an update on the previously written report on Mereo BioPharma Group, a London-based clinical-stage biopharma. Frustrated with the lack of engagement from the management, the activist filled a request for a special shareholder meeting aiming to replace 4 incumbent directors. Rubric Capital, the activist, plans to monetize the pipeline assets, reduce cash burn and distribute excess cash. Activist values the company at $4 per share vs $1/share price today. Despite a potentially large upside, there are several material risks that need to be considered. This is an update following my June report on Mereo BioPharma Group (MREO), a London-based clinical-stage biopharma. More background information on the company and the activist can be found there. A quick recap of main developments - at the time of the initial pitch MREO was trading 10% below $0.87/share of net cash, with the activist, Rubric Capital (14% stake), urging the board to explore strategic alternatives. The main objective of the activist was to monetize the royalty rights to the Setrusumab, a potential treatment for osteogenesis, cost-sharing partnership agreements, and wind down the rest of the pipeline. The activist identified insurmountable costs associated with the development of an early-stage pipeline and the increasing cost of capital as reasons for the change. Rubric valued MREO at $4 per ADS (vs 0.8/share price of MREO at the time) or 540% upside if monetized. Initially, the setup was attractive due to the downside protection provided by the discount to net cash with the activist campaign's success providing a chance for an outsized return. Recent events The day I uploaded the article, rumors came out that AstraZeneca was eyeing a potential acquisition of MREO for $5/share. On the announcement, the stock shot up by 62%, quickly eliminating whatever was left of the discount to net cash reaching a $1.6/share price at the peak. Despite the initial excitement due to lack of updates the shares gradually declined to $1.3/share, still staying well-above net cash levels, up until the emergence of the latest news. Last month Rubric Capital, frustrated with the lack of engagement from the management, sent out a letter to the board calling for a special meeting and nominating a slate of 4 nominees to the board aiming to replace 4 out of 10 incumbent directors including the Chairman as well as the deputy Chairman. The management did not take the request lightly, questioning the experience and fit of the activist nominees in their response letter. Plus the board has identified multiple deficiencies (see below) in the filling procedure for the special shareholder meeting, leaving the feeling that it was done just to drag the process along. The response was not well received by the shareholders. Right after the release of the response letter, MREO shares tumbled by 25% to below $1/share. List of deficiencies identified by the board: Deficiency 1: Rubric owns ADSs, not Ordinary Shares Deficiency 2: The requisition doesn't come from two "members" Deficiency 3: The requisition is in the short-form format and needs to be in the long-form Deficiency 4: Our letter within the requisition exceeds the 1,000-word count limit (by 86 words) Finally, on the 14th of September, the activist released another public letter stating that they have addressed the identified deficiencies and submitted a new request. Unless the management comes up with some other excuse, the special shareholder meeting will likely be convened no later than 21 days after the submission of the request. If the special meeting will be allowed, Rubric has a good chance to win the vote. Further thoughts and valuation First, let's present the activist's model: Activist Letter The most notable asset of the company is Setrusumab, a drug used for the treatment of Osteogenesis imperfecta a rare genetic disease. The integral part of the MREO story is its partnership with Ultragenyx since 2020. The partnership significantly boosted MREO's financial health in the coming years due to a $50 million upfront payment from Ultragenyx. Most importantly, MREO is entitled to significant payments if certain milestones are achieved with further royalty payouts post-FDA approval. These two components make up most of the activist valuation plus the cash on hand (lower by $24m today). Setrusumab will go into Phase 3 trial by the end of the year, which would likely be one of the milestones triggering another payment (the exact details are limited). Moreover, the valuation does not include 5 other earlier-stage drugs that can also yield additional value here. Clearly, despite the contingencies, the potential upside is significant here. Once again, Rubric plans to monetize the potential royalties from Setrusumab, liquidate or license/partner out the rest of the pipeline, reduce the cash burn, and distribute excess cash to shareholders. The success of the campaign will be the catalyst for potentially outsized returns if the assets are monetized at least at a directionally close price to the activist valuation estimates. However, the main questions are whether the activist can succeed in overthrowing the board and if there are any buyers out there for MREO assets. If the shareholder meeting is convened, I believe, the activist has a good chance of succeeding here, for several reasons. Besides its large 14% stake, a close affiliate of Rubric Capital, Point72 Asset Management, also holds a 9% stake in the company and it is highly likely that their vote is in the pocket of the activist. In fact, Rubric Capital was a part of Point72 before it was carved out in 2016. Point72 capital is a hedge fund run by the infamous Steve Cohen whose former analyst was David Rosen, the current CEO of Rubric Capital. Moreover, to request a special shareholder meeting holders of ADS have to convert their ADS into ordinary shares with a $0.05/share conversion fee. Despite this, the activist was willing to incur, basically, a 10% tax just to request the shareholder meeting which speaks highly of their determination and most importantly confidence that the vote will go in their favor. On top of this, shareholder reaction to the management's response clearly shows dissatisfaction with the current management further increasing the likelihood of a successful activist campaign.
Seeking Alpha • Sep 14

Mereo activist investor Rubric asks board again to hold general meeting, nominate directors

Rubric Capital Management submitted a revised requisition to Mereo BioPharma's (NASDAQ:MREO) board for a general meeting of shareholders. Rubric — which claims to own ~14% stake in Mereo — issued an open letter on Sept. 14 criticizing the company and urged Mereo to hold a general meeting and allow shareholders to vote on Rubric's proposals, including the nomination of new board members. On Aug. 22, Mereo had cited certain deficiencies in Rubric's original requisition seeking the general meeting. A few days prior to this, in an Aug. 19 letter, Rubric had asked to hold a general meeting to consider the removal of directors Peter Fellner, Anders Ekblom, Deepika Pakianathan, and Michael Wyzga and to appoint Annalisa Jenkins, Daniel Shames, Marc Yoskowitz, and Justin Roberts as directors. In the Sept. 14 open letter Rubric disclosed the deficiencies cited by Mereo and its response.
Seeking Alpha • Jul 05

Mereo BioPharma Group regains compliance with Nasdaq's listing rule

Mereo BioPharma Group (NASDAQ:MREO) stated Tuesday that it has regained compliance with Nasdaq's minimum $1 bid price requirement as notified by the exchange. Stock is up 2.9% in after-hours trading. Earlier: AstraZeneca considering bid for Mereo BioPharma – Report (update)
Seeking Alpha • Jun 17

Mereo BioPharma: Activist Pressure In A Net-Net Biopharma

Mereo BioPharma Group plc is a London-based clinical-stage biopharma trading at a slight discount to net cash. Recently, one of the company’s largest investors, Rubric Capital Management (14% stake), wrote a letter to the board urging them to explore strategic alternatives. Rubric Capital is estimating that the implied value of MREO today is $4 per ADS.
Seeking Alpha • Dec 08

Mereo BioPharma: Anti-TIGIT Developer In Mid-Stage Development

MREO is a British company developing a new kind of monoclonal antibody for cancer. The company's self-owned pipeline is in the early stage. They recently announced interim data from a phase 1b trial.

Aktionärsrenditen

MREOUS BiotechsUS Markt
7D10.6%-1.6%-0.8%
1Y-88.1%34.4%27.1%

Rendite im Vergleich zur Industrie: MREO unter dem Niveau der Branche US Biotechs , die im vergangenen Jahr eine Rendite von 34.4% erzielte.

Rendite vs. Markt: MREO hinter dem Markt US zurück, der im vergangenen Jahr eine Rendite von 27.1 erzielte.

Preisvolatilität

Is MREO's price volatile compared to industry and market?
MREO volatility
MREO Average Weekly Movement10.3%
Biotechs Industry Average Movement11.0%
Market Average Movement7.2%
10% most volatile stocks in US Market16.3%
10% least volatile stocks in US Market3.2%

Stabiler Aktienkurs: MREO hatte in den letzten 3 Monaten im Vergleich zum US -Markt keine signifikante Preisvolatilität.

Volatilität im Zeitverlauf: MREODie wöchentliche Volatilität der Aktie ist im vergangenen Jahr von 19% auf 10% zurückgegangen.

Über das Unternehmen

GegründetMitarbeiterCEOWebsite
201539Denise Scots-Knightwww.mereobiopharma.com

Mereo BioPharma Group plc, ein biopharmazeutisches Unternehmen, entwickelt und vermarktet Therapeutika für die Behandlung seltener Krankheiten im Vereinigten Königreich und in den Vereinigten Staaten. Das Unternehmen entwickelt Setrusumab, einen Antikörper zur Behandlung der Osteogenesis imperfecta, Alvelestat, ein oral verabreichtes kleines Molekül, das sich in der klinischen Phase II zur Behandlung der mit dem Alpha-1-Antitrypsin-Mangel verbundenen Lungenerkrankung befindet, und Vantictumab, einen monoklonalen Anti-FZD-Antikörper zur Behandlung der autosomal dominanten Osteopetrose Typ 2. Darüber hinaus entwickelt das Unternehmen Leflutrozol, einen oralen Aromatasehemmer, der sich in Phase-2-Studien zur Behandlung des hypogonadotropen Hypogonadismus befindet, sowie Navicixizumab, das klinische Studien der Phase 1b zur Behandlung von Eierstockkrebs in der Spätphase abgeschlossen hat; Etigilimab, ein monoklonaler IgG1-Antikörper, der an den menschlichen TIGIT-Rezeptor auf Immunzellen bindet, zur Behandlung von fortgeschrittenen soliden Tumoren; und Acumapimod, ein p38-MAP-Kinase-Inhibitor, der sich in klinischen Studien der Phase II zur Behandlung akuter Exazerbationen der chronisch obstruktiven Lungenerkrankung befindet.

Mereo BioPharma Group plc's Grundlagenzusammenfassung

Wie verhalten sich die Erträge und Einnahmen von Mereo BioPharma Group im Vergleich zum Marktanteil des Unternehmens?
MREO grundlegende Statistiken
MarktanteilUS$45.12m
Gewinn(TTM)-US$35.71m
Umsatz(TTM)US$500.00k
86.9x
Kurs-Umsatz-Verhältnis
-1.2x
Kurs-Gewinn-Verhältnis

Ist MREO zu teuer?

Siehe Fair Value und Bewertungsanalyse

Erträge & Einnahmen

Wichtige Rentabilitätsstatistiken aus dem letzten Ergebnisbericht (TTM)
MREO Gewinn- und Verlustrechnung (TTM)
EinnahmenUS$500.00k
Kosten der EinnahmenUS$133.00k
BruttogewinnUS$367.00k
Sonstige AusgabenUS$36.08m
Gewinn-US$35.71m

Zuletzt gemeldete Gewinne

Mar 31, 2026

Datum des nächsten Gewinnberichts

k.A.

Gewinn per Aktie (EPS)-0.22
Bruttomarge73.40%
Nettogewinnspanne-7,142.00%
Schulden/Eigenkapital-Verhältnis0%

Wie hat sich MREO auf lange Sicht entwickelt?

Historische Performance und Vergleiche

Unternehmensanalyse und Finanzdaten Status

DatenZuletzt aktualisiert (UTC-Zeit)
Unternehmensanalyse2026/05/21 20:14
Aktienkurs zum Tagesende2026/05/21 00:00
Gewinne2026/03/31
Jährliche Einnahmen2025/12/31

Datenquellen

Die in unserer Unternehmensanalyse verwendeten Daten stammen von S&P Global Market Intelligence LLC. Die folgenden Daten werden in unserem Analysemodell verwendet, um diesen Bericht zu erstellen. Die Daten sind normalisiert, was zu einer Verzögerung bei der Verfügbarkeit der Quelle führen kann.

PaketDatenZeitrahmenBeispiel US-Quelle *
Finanzdaten des Unternehmens10 Jahre
  • Gewinn- und Verlustrechnung
  • Kapitalflussrechnung
  • Bilanz
Konsensschätzungen der Analysten+3 Jahre
  • Finanzielle Vorausschau
  • Kursziele der Analysten
Marktpreise30 Jahre
  • Aktienkurse
  • Dividenden, Splits und Aktionen
Eigentümerschaft10 Jahre
  • Top-Aktionäre
  • Insiderhandel
Verwaltung10 Jahre
  • Das Führungsteam
  • Direktorium
Wichtige Entwicklungen10 Jahre
  • Ankündigungen des Unternehmens

* Beispiel für US-Wertpapiere, für nicht-US-amerikanische Wertpapiere werden gleichwertige regulatorische Formulare und Quellen verwendet.

Sofern nicht anders angegeben, beziehen sich alle Finanzdaten auf einen Jahreszeitraum, werden aber vierteljährlich aktualisiert. Dies wird als Trailing Twelve Month (TTM) oder Last Twelve Month (LTM) Daten bezeichnet. Erfahren Sie mehr.

Analysemodell und Schneeflocke

Einzelheiten zu dem Analysemodell, mit dem dieser Bericht erstellt wurde, finden Sie auf unserer Github-Seite. Außerdem bieten wir Leitfäden zur Verwendung unserer Berichte und Tutorials auf YouTube an.

Erfahren Sie mehr über das Weltklasse-Team, das das Simply Wall St-Analysemodell entworfen und entwickelt hat.

Metriken für Industrie und Sektor

Unsere Branchen- und Sektionskennzahlen werden alle 6 Stunden von Simply Wall St berechnet. Details zu unserem Verfahren finden Sie auf Github.

Analysten-Quellen

Mereo BioPharma Group plc wird von 11 Analysten beobachtet. 7 dieser Analysten hat die Umsatz- oder Gewinnschätzungen übermittelt, die als Grundlage für unseren Bericht dienen. Die von den Analysten übermittelten Daten werden im Laufe des Tages aktualisiert.

AnalystEinrichtung
Jack AllenBaird
Yun ZhongBTIG
Julian HarrisonBTIG