Shared on 22 Jun 26

Fair value Decreased 2.11%

ZYME: Ovarian Cancer Data And Fast Track Status Will Drive Repricing

New early trial results for Zymeworks’ ovarian and endometrial cancer drug show strong tumor shrinkage, and the FDA gives the program a faster review path — both could shift how investors view the company’s outlook. At the same time, analysts debate how much these results really compare with rivals’ studies, and how quickly new data could swing market mood.

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Shared on 29 Apr 26

ZYME: Royalty Model Shift Will Rely On Upcoming HER2 Gastric Trial Data

Narrative Update on Zymeworks Analysts have lifted Zymeworks' implied price target range into the mid to high $40s, citing the $250m Royalty Pharma debt deal and a shift toward a more royalty focused model as key reasons for refining assumptions around profitability and a higher future P/E multiple. Analyst Commentary Recent Street research has been broadly constructive on Zymeworks, with several price target increases clustered in the mid to high $40s.

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Shared on 14 Apr 26

Fair value Increased 9.92%

ZYME: Royalty Model Outlook Will Hinge On Upcoming HER2 Gastric Cancer Data

Analysts have raised Zymeworks’ fair value estimate from about $36.46 to $40.08, citing higher price targets in the $46 to $48 range, supportive views on the $250m Royalty Pharma financing, and a shift toward a more royalty-focused business model. Analyst Commentary Recent Street research has focused on Zymeworks’ financing decisions, its pivot toward a royalty-driven model, and the pipeline events that could influence how investors think about execution and valuation.

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Shared on 17 Feb 26

Fair value Increased 2.38%

ZYME: Royalty Model Will Be Supported By Upcoming HER2 Gastric Cancer Data

Analysts have raised their price targets on Zymeworks, with one firm moving to $40 from $37 and another to $25 from $17, citing the company's shift toward a royalty-focused model and expectations around upcoming HERIZON GEA-01 data as key drivers. Analyst Commentary Bullish Takeaways Bullish analysts point to the shift toward a royalty-focused model as a key reason for higher price targets, arguing that recurring royalty streams can support more visible revenue over time.

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Shared on 03 Feb 26

Fair value Increased 3.23%

ZYME: Royalty Model Will Be Driven By Positive HER2 Gastric Cancer Data

Narrative Update Analysts have nudged their blended price target for Zymeworks higher from about $34.50 to roughly $35.62 as they factor in the company’s shift toward a royalty-focused model around zani, positive HERIZON-GEA data for Ziihera, and updated views on future profitability and P/E assumptions. Analyst Commentary Street research on Zymeworks is clustering around two main themes: the shift toward a royalty-focused model centered on zani, and the impact of recent clinical data for Ziihera and early pipeline assets.

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Shared on 04 Dec 25

Fair value Increased 0.88%

ZYME: Royalty Model Will Benefit From Positive HER2 Gastric Cancer Data

Analysts nudged their fair value estimate for Zymeworks slightly higher, from $34.20 to $34.50. This reflects growing confidence that the company’s shift toward a royalty aggregator model, coupled with strong HERIZON-GEA-01 data for Ziihera and encouraging early ZW191 results, can drive faster revenue growth and improved profitability.

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Shared on 20 Nov 25

Fair value Increased 40%

ZYME: Recurring Royalty Revenue Will Drive Momentum After Positive Clinical Results

Zymeworks' analyst price target has surged from approximately $24.45 to $34.20 per share. This increase reflects analysts' optimism following the company's positive clinical trial results and strategic shift toward generating recurring royalty revenues.

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Shared on 05 Nov 25

Fair value Increased 3.26%

ZYME: Encouraging Pipeline Data Will Drive Momentum Ahead Of Key Clinical Readouts

Analysts have raised their price target for Zymeworks from $23.68 to $24.45 per share. They cite increased confidence in the company's growth outlook following encouraging clinical data and expanding therapeutic opportunities.

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Shared on 22 Oct 25

Fair value Increased 10%

Analysts have increased their price target for Zymeworks from $21.45 to $23.68 per share. They cite the company's differentiated therapies and upcoming clinical milestones as key drivers for the revised outlook.

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Shared on 08 Oct 25

Fair value Increased 6.95%

Analysts have increased their price target for Zymeworks from $20.06 to $21.45, citing improving revenue growth forecasts, stronger projected profit margins, and growing confidence in the momentum of Zanidatamab in biliary tract cancer. Analyst Commentary Recent commentary from street research reflects a mix of optimism and caution surrounding Zymeworks, particularly as the company advances its lead asset, Zanidatamab, in the biliary tract cancer market.

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Shared on 20 Sep 25

Fair value Decreased 4.72%

Despite raised analyst confidence driven by positive clinical momentum for Zanidatamab and anticipated catalysts, Zymeworks’ consensus analyst price target has been modestly lowered from $21.05 to $20.06. Analyst Commentary Positive momentum for Zanidatamab in biliary tract cancer.

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Shared on 01 May 25

Fair value Decreased 19%

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Shared on 24 Apr 25

Fair value Increased 20%

AnalystConsensusTarget made no meaningful changes to valuation assumptions.

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Shared on 17 Apr 25

Fair value Decreased 17%

1 view

Shared on 09 Apr 25

AnalystConsensusTarget made no meaningful changes to valuation assumptions.

1 view

Shared on 02 Apr 25

Fair value Increased 20%

AnalystConsensusTarget has increased revenue growth from 12.4% to 16.9%, increased profit margin from 10.5% to 19.3%, decreased future PE multiple from 120.8x to 71.9x and increased shares outstanding growth rate from -0.0% to -0.0%.

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Analysts Raise Zymeworks Target on Pipeline Progress While Weighing Risks and Valuation Changes

ZYME: Ovarian Cancer Data And Fast Track Status Will Drive Repricing

ZYME: Royalty Model Shift Will Rely On Upcoming HER2 Gastric Trial Data

ZYME: Royalty Model Outlook Will Hinge On Upcoming HER2 Gastric Cancer Data

ZYME: Royalty Model Will Be Supported By Upcoming HER2 Gastric Cancer Data

ZYME: Royalty Model Will Be Driven By Positive HER2 Gastric Cancer Data

ZYME: Royalty Model Will Benefit From Positive HER2 Gastric Cancer Data

ZYME: Recurring Royalty Revenue Will Drive Momentum After Positive Clinical Results

ZYME: Encouraging Pipeline Data Will Drive Momentum Ahead Of Key Clinical Readouts

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