REC-617 And REC-994 Trials Will Drive Future AI-Driven Drug Discovery Success

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AnalystConsensusTarget
Consensus Narrative from 6 Analysts
Published
22 Mar 25
Updated
01 Aug 25
AnalystConsensusTarget's Fair Value
US$6.67
14.8% undervalued intrinsic discount
01 Aug
US$5.68
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1Y
-19.1%
7D
-12.5%

Author's Valuation

US$6.7

14.8% undervalued intrinsic discount

AnalystConsensusTarget Fair Value

Last Update01 Aug 25
Fair value Decreased 6.67%

Recursion Pharmaceuticals’ consensus price target has been revised downward to $6.67 as analysts cite sector volatility, disappointing early clinical results, unresolved questions around pipeline valuation and revenue drivers, and the company’s early-stage status as key concerns.


Analyst Commentary


  • Volatility driven by macroeconomic factors impacting the biotech sector.
  • Underperformance observed in initial clinical trial results.
  • Ongoing uncertainty regarding valuation and future revenue drivers.
  • Recent pipeline prioritization creating further questions around asset value.
  • Early-stage clinical development status leaving significant open questions about the company's long-term potential.

What's in the News


  • Recursion open-sourced Boltz-2, a next-generation biomolecular AI model that achieves near physics-based accuracy in structure and binding affinity prediction at speeds up to 1,000x faster, addressing a major bottleneck in small molecule discovery; the model, weights, and pipeline are available for both academic and commercial use under an MIT license.
  • Preliminary Phase 1b/2 TUPELO trial results for REC-4881 in Familial Adenomatous Polyposis showed a median 43% reduction in polyp burden at Week 13 among efficacy-evaluable patients; REC-4881 has Fast Track and Orphan Drug designations from both U.S. and European regulators.

Valuation Changes


Summary of Valuation Changes for Recursion Pharmaceuticals

  • The Consensus Analyst Price Target has fallen from $7.14 to $6.67.
  • The Future P/E for Recursion Pharmaceuticals has significantly fallen from 236.64x to 178.94x.
  • The Net Profit Margin for Recursion Pharmaceuticals has significantly risen from 10.54% to 12.20%.

Key Takeaways

  • Successful clinical trials and expanded pipeline indicate promising future revenue growth and earnings from potential drug market entries.
  • Strategic partnerships and operational synergies enhance cash flow, efficiencies, and computational capabilities, supporting robust future earnings growth.
  • Early-stage clinical uncertainties, reliance on partnerships, and high R&D expenses, combined with significant cash burn and integration challenges, pose risks to financial stability.

Catalysts

About Recursion Pharmaceuticals
    Operates as a clinical-stage biotechnology company, engages in the decoding biology and chemistry by integrating technological innovations across biology, chemistry, automation, data science, and engineering to industrialize drug discovery in the United States.
What are the underlying business or industry changes driving this perspective?
  • The positive clinical data readouts from Recursion's REC-617 and REC-994 trials, including the potential best-in-class efficacy signals, suggest future revenue growth potential as these drugs move through further development and potentially to market.
  • The launch of multiple additional trials and continued pipeline expansion with new promising molecules signal future increases in revenue streams and potential for higher earnings upon successful development milestones.
  • The merger with Exscientia has resulted in operational synergies and enhanced data-driven capabilities, indicating improved net margins and increased efficiencies that could impact future earnings positively.
  • Strong partnerships with major pharmaceutical companies like Roche and Sanofi provide milestone payments and validate Recursion's technology, contributing to robust cash flows and improved revenue growth expectations.
  • The development of the BioHive-2 supercomputer with NVIDIA enhances Recursion's computational capabilities, likely leading to faster drug discovery processes, reduced costs, and future growth in earnings and revenue through more efficient operations.

Recursion Pharmaceuticals Earnings and Revenue Growth

Recursion Pharmaceuticals Future Earnings and Revenue Growth

Assumptions

How have these above catalysts been quantified?
  • Analysts are assuming Recursion Pharmaceuticals's revenue will grow by 45.2% annually over the next 3 years.
  • Analysts are not forecasting that Recursion Pharmaceuticals will become profitable in next 3 years. To represent the Analyst Price Target as a Future PE Valuation we will estimate Recursion Pharmaceuticals's profit margin will increase from -961.3% to the average US Biotechs industry of 10.5% in 3 years.
  • If Recursion Pharmaceuticals's profit margin were to converge on the industry average, you could expect earnings to reach $19.3 million (and earnings per share of $0.04) by about July 2028, up from $-574.8 million today.
  • In order for the above numbers to justify the analysts price target, the company would need to trade at a PE ratio of 236.6x on those 2028 earnings, up from -4.9x today. This future PE is greater than the current PE for the US Biotechs industry at 16.5x.
  • Analysts expect the number of shares outstanding to grow by 7.0% per year for the next 3 years.
  • To value all of this in today's terms, we will use a discount rate of 6.4%, as per the Simply Wall St company report.

Recursion Pharmaceuticals Future Earnings Per Share Growth

Recursion Pharmaceuticals Future Earnings Per Share Growth

Risks

What could happen that would invalidate this narrative?
  • The relatively early stage of clinical evidence and reliance on signal-finding studies for programs like REC-617 and REC-994 may introduce uncertainties in proving efficacy, potentially affecting long-term revenue and profitability if these initial results do not lead to successful commercialization.
  • Dependence on achieving milestones and maintaining partnerships for a significant portion of revenue creates variability, as milestone payments are unpredictable and not guaranteed, impacting cash flow and earnings stability.
  • The ambitious technological vision for creating a virtual cell and associated high reliance on complex data and supercomputing capabilities may involve substantial R&D expenses without immediate financial return, affecting net margins and financial sustainability.
  • The market risk of competition or potential industry shifts in the AI-driven drug discovery space could reduce Recursion's perceived competitive edge, potentially impacting future revenue growth and market share.
  • High cash burn rates and the complex integration challenges from the merger with Exscientia may dilute net earnings if expected synergies and operational efficiencies do not materialize as planned.

Valuation

How have all the factors above been brought together to estimate a fair value?
  • The analysts have a consensus price target of $7.143 for Recursion Pharmaceuticals based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $10.0, and the most bearish reporting a price target of just $4.0.
  • In order for you to agree with the analyst's consensus, you'd need to believe that by 2028, revenues will be $183.2 million, earnings will come to $19.3 million, and it would be trading on a PE ratio of 236.6x, assuming you use a discount rate of 6.4%.
  • Given the current share price of $6.54, the analyst price target of $7.14 is 8.4% higher. The relatively low difference between the current share price and the analyst consensus price target indicates that they believe on average, the company is fairly priced.
  • We always encourage you to reach your own conclusions though. So sense check these analyst numbers against your own assumptions and expectations based on your understanding of the business and what you believe is probable.

How well do narratives help inform your perspective?

Disclaimer

AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.

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