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Extended Cash Runway Will Support Pivotal Phase III Clinical Milestones

Published
08 Apr 25
Updated
28 Oct 25
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AnalystConsensusTarget's Fair Value
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1Y
-60.8%
7D
-11.0%

Author's Valuation

US$15.6767.1% undervalued intrinsic discount

AnalystConsensusTarget Fair Value

Shared on 28 Oct 25

Fair value Decreased 32%

Karyopharm Therapeutics' analyst price target has been reduced sharply from approximately $23.07 to $15.67 per share. Analysts cite the company’s recent strategic financing measures and updated projections following extended cash runway and upcoming clinical milestones.

Shared on 13 Oct 25

Fair value Decreased 11%

Phase III Trials And Global Partnerships Will Advance Personalized Medicine

Karyopharm Therapeutics' analyst price target has been reduced from $8 to $6. This reflects analysts' views that, while strategic financing has extended the company's cash runway into Q2 2026, financial constraints and the timeline to key clinical trial readouts warrant a tempered outlook.

Shared on 15 Aug 25

Phase III Trials And Global Partnerships Will Advance Personalized Medicine

Karyopharm Therapeutics’ net profit margin has improved and its future P/E has declined—indicating stronger profitability and a more attractive valuation—while the consensus analyst price target remains unchanged at $25.92. What's in the News Provided 2025 earnings guidance, expecting total revenue between $140 million and $155 million, including U.S. XPOVIO net product and partner-derived revenue.

Shared on 01 May 25

Fair value Decreased 42%

Phase III Trials And Global Partnerships Will Advance Personalized Medicine

Shared on 24 Apr 25

Fair value Increased 54%

Phase III SENTRY And XPOVIO Approvals Will Secure Future Success

AnalystConsensusTarget made no meaningful changes to valuation assumptions.

Shared on 17 Apr 25

Fair value Decreased 1.10%

Phase III SENTRY And XPOVIO Approvals Will Secure Future Success