Last Update 05 Dec 25
HROW: Expanding Ophthalmic Portfolio Will Drive Long-Term Revenue Mix Diversification
Analysts have raised their blended price targets for Harrow into a higher range, highlighted by recent increases to $66, $70, $74, and $94 per share. They cite a stronger long-term revenue and margin outlook supported by ophthalmic biosimilars, Vevye ramp expectations, and a more visible commercial roadmap.
Analyst Commentary
Analyst revisions across the Street underscore growing confidence in Harrow's long term growth algorithm, with successive target hikes clustered in the mid to high double digits. The updates follow both quarterly results and recent investor and analyst days, which have provided greater visibility into the company’s commercial roadmap, revenue mix, and margin trajectory.
While most perspectives remain optimistic, the latest research also highlights execution hurdles that will need to be cleared for the company to fully justify higher valuation levels.
Bullish Takeaways
- Bullish analysts see the higher targets as justified by a clearer line of sight to sustained revenue and margin expansion, driven by the ophthalmic portfolio and scaling of newer assets.
- Multiple models now embed meaningful contributions from Vevye, with expectations that ramping prescriptions and broader market penetration can support a premium growth multiple over the next several years.
- The addition of ophthalmic biosimilars is viewed as an underappreciated growth lever, with some forecasts calling for material revenue contributions beginning in 2026 that could diversify and de risk the top line.
- Management has reiterated its ambition to build to $250M plus in quarterly revenue by late 2027, and bullish analysts argue that the updated targets still leave upside if the company executes even near the midpoint of that framework.
Bearish Takeaways
- Bearish analysts caution that near term Vevye revenue is tracking modestly below prior targets, which raises the bar for 2026 growth and increases sensitivity to payer coverage and competitive dynamics.
- There is concern that the valuation now bakes in a high degree of success on both Vevye and biosimilars, leaving less room for operational missteps or slower than expected adoption.
- Some models flag uncertainty around the specific commercial strategies for the biosimilar franchise, noting that limited disclosure on contracting and field deployment could introduce execution risk to out year estimates.
- Higher price targets tighten the margin for error, and more cautious views emphasize that Harrow will need to consistently hit or beat quarterly milestones to support the upgraded expectations embedded in current models.
What's in the News
- Updated 2025 revenue guidance to a slightly more conservative range of $270 million to $280 million, while noting that the original target of over $280 million remains achievable with strong execution (Company guidance filing)
- Launched the Harrow Access for All program to cap out-of-pocket costs at $59 for eligible patients and expand affordable access across branded, generic, and compounded ophthalmic medicines. The program will start with key specialty products in late 2025 and is expected to scale to the full portfolio by 2027 (Company program announcement)
- Announced the upcoming launch of BYQLOVI, a clobetasol propionate ophthalmic suspension 0.05 percent, as part of the initial phase of the Harrow Access for All rollout to support early adoption of new specialty products (Company program announcement)
- Replaced Crowe LLP with Deloitte and Touche LLP as the independent registered public accounting firm, effective for the 2025 fiscal year audit, following action by the company’s Audit Committee (Company 8 K disclosure)
Valuation Changes
- Fair Value: Unchanged at approximately $70.63 per share, indicating a stable long term intrinsic value assessment.
- Discount Rate: Edged down slightly from about 6.96 percent to 6.96 percent, reflecting a marginally lower implied risk profile.
- Revenue Growth: Essentially flat, holding near 39.51 percent, suggesting no material change in long term top line growth expectations.
- Net Profit Margin: Stable at roughly 26.50 percent, indicating consistent assumptions around long term profitability.
- Future P/E: Remains effectively unchanged at about 19.69x, signaling a steady view on Harrow’s forward valuation multiple.
Key Takeaways
- Accelerating demand for Harrow's specialty eye drugs and expansion into new treatment areas support strong, sustained top-line and margin growth.
- Improved patient access, partnerships, and integration of new innovative products strengthen competitive positioning and enable outsized earnings growth.
- Heavy dependence on flagship products, unsustainable recent growth, high execution risks, and pricing pressures threaten Harrow's revenue stability, margin expansion, and long-term profitability.
Catalysts
About Harrow- An eyecare pharmaceutical company, engages in the discovery, development, and commercialization of ophthalmic pharmaceutical products.
- The rapidly growing demand for Harrow's portfolio of specialty ophthalmic drugs, particularly VEVYE, IHEEZO, and TRIESENCE, is positioned to accelerate further as aging populations and increased prevalence of chronic ocular diseases expand the baseline patient pool-supporting sustainable long-term revenue growth.
- Strategic expansion into new indications and broader patient segments (e.g., TRIESENCE's expected launch into the large ocular inflammation market and BYQLOVI's entry into the post-operative care segment), coupled with rising healthcare access and coverage in the U.S., should increase prescription volumes and elevate top-line performance.
- Operating leverage is set to improve meaningfully as Harrow's scalable commercial infrastructure-already built out and profitable-absorbs additional high-margin revenue from both organic growth (e.g., expanded refill rates, market share gains) and new product launches, likely driving further net margin expansion.
- Enhanced distribution and patient access programs (such as the VAFA initiative and partnerships with Apollo Care) are reducing access barriers and converting more commercial insurance-covered prescriptions at higher average selling prices, directly benefitting both revenue quality and gross margins.
- Harrow's ability to secure, integrate, and commercialize new branded and biosimilar ophthalmic assets (notably the Samsung biosimilars portfolio and BYQLOVI) leverages secular shifts toward preference for innovative/specialty medications, positioning the company for outsized earnings growth as competitive barriers rise in a consolidating, increasingly regulated sector.
Harrow Future Earnings and Revenue Growth
Assumptions
How have these above catalysts been quantified?- Analysts are assuming Harrow's revenue will grow by 37.1% annually over the next 3 years.
- Analysts assume that profit margins will increase from -4.5% today to 35.6% in 3 years time.
- Analysts expect earnings to reach $209.0 million (and earnings per share of $4.03) by about September 2028, up from $-10.2 million today.
- In order for the above numbers to justify the analysts price target, the company would need to trade at a PE ratio of 14.4x on those 2028 earnings, up from -135.1x today. This future PE is lower than the current PE for the US Pharmaceuticals industry at 19.5x.
- Analysts expect the number of shares outstanding to grow by 3.9% per year for the next 3 years.
- To value all of this in today's terms, we will use a discount rate of 6.78%, as per the Simply Wall St company report.
Harrow Future Earnings Per Share Growth
Risks
What could happen that would invalidate this narrative?- Heavy reliance on a few flagship products like VEVYE, IHEEZO, and TRIESENCE exposes Harrow to significant competitive and generic risk; any loss of market exclusivity, failure to achieve further market penetration, or competitive product launches could lead to notable revenue declines and impair long-term earnings.
- Recent rapid growth in flagship products may not be sustainable-management acknowledged that some surges (e.g., VEVYE growth) were driven by temporary patient switches or program-driven boluses, and future growth rates could slow if organic demand normalizes, directly impacting revenue trajectory and earnings growth expectations.
- Harrow's aggressive sales and revenue guidance, especially for the Specialty Branded segment and TRIESENCE, is contingent on "overperforming" in execution, successful penetration into new markets, and ramp-up of new leadership; if key launches underperform or operational challenges emerge, forecasted revenue and net margin expansion could fall short.
- Expansion into biosimilars and new product classes carries integration and execution risk; operational missteps, regulatory delays, or slower-than-expected market uptake could increase SG&A/R&D costs, hurt operating leverage, and delay profitability improvements.
- Persistent pressure on drug pricing and reimbursement in the U.S. and from public payers (especially as Harrow increases exposure to insurance reimbursed markets) could compress average selling prices (ASPs), limit future price increases, and restrict net margin expansion even if prescription volumes rise.
Valuation
How have all the factors above been brought together to estimate a fair value?- The analysts have a consensus price target of $60.1 for Harrow based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $76.0, and the most bearish reporting a price target of just $42.0.
- In order for you to agree with the analyst's consensus, you'd need to believe that by 2028, revenues will be $586.7 million, earnings will come to $209.0 million, and it would be trading on a PE ratio of 14.4x, assuming you use a discount rate of 6.8%.
- Given the current share price of $37.34, the analyst price target of $60.1 is 37.9% higher.
- We always encourage you to reach your own conclusions though. So sense check these analyst numbers against your own assumptions and expectations based on your understanding of the business and what you believe is probable.
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Disclaimer
AnalystConsensusTarget is a tool utilizing a Large Language Model (LLM) that ingests data on consensus price targets, forecasted revenue and earnings figures, as well as the transcripts of earnings calls to produce qualitative analysis. The narratives produced by AnalystConsensusTarget are general in nature and are based solely on analyst data and publicly-available material published by the respective companies. These scenarios are not indicative of the company's future performance and are exploratory in nature. Simply Wall St has no position in the company(s) mentioned. Simply Wall St may provide the securities issuer or related entities with website advertising services for a fee, on an arm's length basis. These relationships have no impact on the way we conduct our business, the content we host, or how our content is served to users. The price targets and estimates used are consensus data, and do not constitute a recommendation to buy or sell any stock, and they do not take account of your objectives, or your financial situation. Note that AnalystConsensusTarget's analysis may not factor in the latest price-sensitive company announcements or qualitative material.



