Tillkännagivande • Feb 10

Anixa Biosciences Inc. Reports Encouraging Patient Survival Observations in Ovarian Cancer CAR-T Trial; Achieves Regulatory Approval Enabling Major Dose Escalation

Anixa Biosciences, Inc. provided an update on patient outcomes observed in its ongoing Phase 1 ovarian cancer CAR-T clinical trial, following regulatory approval of a protocol amendment that enables substantial dose escalation. The ongoing Phase 1 trial is enrolling adult women with recurrent ovarian cancer, who have failed standard of care chemotherapy, and progressed after two or more prior therapies. To date, twelve patients have been treated in the trial at four dosage levels. Of these patients, seven have lived beyond their expected median survival of approximately three to four months, based on disease stage and prior therapy history. One patient survived 28 months following treatment, three patients have survived greater than one year following treatment (17, 15 and 14 months, respectively) and three patients have survived 11, 8 and 8 months, respectively. Three patients that have reached 15, 14 and 8 months remain alive, and one additional patient who was treated more recently, is also currently alive.While the study is designed to primarily demonstrate safety, Anixa believes this pattern of extended survival represents encouraging, albeit anecdotal, evidence of clinical activity in a patient population with limited therapeutic options. These survival observations have been accompanied by a clean safety profile. Importantly, no dose-limiting toxicities (DLTs) have been observed to date, prompting Anixa's partner, Moffitt Cancer Center ("Moffitt"), to obtain Institutional Review Board (IRB) approval for a protocol amendment that permits significant dose escalation.Under the amended protocol, dosing may increase from the original range of 1×105 to 1×107 CAR-positive cells per kilogram of body weight ("cells/kg") to as high as 1×10? cells/kg, representing a two-order-of-magnitude increase. If no DLTs are observed at this level, additional escalation may be pursued at the discretion of the principal investigator.Anixa and Moffitt believe the favorable safety profile observed to date is partially attributable to the direct intra-peritoneal delivery of CAR-T cells, which differs from conventional intravenous administration and may reduce systemic toxicity while enhancing localized tumor targeting. As part of the amended study design, the next patient cohort will receive 1×107 cells/kg following treatment with cyclophosphamide and fludarabine, a preparatory regimen known as lymphodepletion. Lymphodepletion reduces competing immune cells, creating a more favorable environment for CAR-T expansion, persistence, and activity. While lymphodepletion is routinely used in CAR-T therapies for hematologic cancers, its role in solid tumors remains investigational. Anixa, Moffitt, and the U.S. Food and Drug Administration view this addition as an important opportunity to assess whether lymphodepletion can further enhance efficacy in a localized solid tumor setting, particularly when combined with intra-peritoneal CAR-T delivery.

Tillkännagivande • Sep 20

Anixa Biosciences, Inc. Establishes Cancer Business Advisory Board

Anixa Biosciences, Inc. announced that it has established a Cancer Business Advisory Board, whose purpose is to provide guidance on the Company's clinical and business development initiatives. The CBAB will be co-chaired by Anixa Chairman and CEO, Dr. Amit Kumar, and Board Director, Dr. Arnold Baskies, and will include the following members: Dr. Kevin Cullen, MD, Dan Heist, Dr. Karen E. Knudsen, MBA, PhD, Dr. Len Lichtenfeld, MD, MACP, Michael T. Marquardt, Scarlott Mueller, MPH, RN, FAAN, Gary Reedy and Rob Youle, JD. Dr. Cullen is the Marlene and Stewart Greenebaum Distinguished Professor in Oncology and Director of the Program in Oncology at the UMSOM. He also serves as director of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center. In 2011, Dr. Cullen was appointed by President Obama to a five-year term as a member of the National Cancer Advisory Board, an advisory committee to the NCI. He previously served as Chairman of the Board of ACS and is a recipient of the ACS Excellence in Research Award. Dr. Cullen received his medical degree from Harvard Medical School. He conducted his residency in internal medicine at Beth Israel Hospital in Boston, MA, and fellowship in oncology with the NCI in Bethesda, MD. Mr. Heist has been the Director of Internal Audit at Penn State since 2003, bringing more than 30 years of auditing and accounting experience. He is active with ACS, serving at the local, state, and national level; and is a past Chairman of the Board of ACS. Previously, Mr. Heist was a Senior Manager at Deloitte & Touche, LLP, and served a variety of both privately and publicly held manufacturing and service industry clients. He received a bachelor of science degree from Penn State. Dr. Knudsen has been the CEO of ACS and its advocacy affiliate, ACS CAN, since 2021. She previously served as Executive Vice President of Oncology Services and Enterprise Director for Sidney Kimmel Cancer Center at Jefferson Health; President for the Association of American Cancer Institutes, representing the 102 leading cancer centers in North America; and on the board of directors of the American Association for Cancer Research. Dr. Knudsen serves on the board of advisors for the National Cancer Institute (NCI) and on 12 external advisory boards for NCI-designated cancer centers. She is an active member of several committees with the American Society for Clinical Oncology, in addition to serving on other academic and for-profit advisory boards. Dr. Knudsen holds a bachelor's degree in biology from George Washington University, a PhD in biological sciences from the University of California San Diego, and an MBA from Temple University Fox School of Business. Dr. Lichtenfeld is an experienced medical oncologist and independent consultant with an extensive background in cancer care, cancer research, healthcare policy, and physician payment. He is a member of the CancerCare board of directors, and an advisor to several early-stage patient- and cancer-focused companies, including Trialjectory and OneHealth. Dr. Lichtenfeld was previously the Chief Medical and Scientific Officer, and Deputy Chief Medical Officer for ACS. He received a bachelor's degree in sociology from the University of Pennsylvania, a medical degree from Hahnemann Medical College (now Drexel University College of Medicine) and medical training at Temple University, Johns Hopkins and the NCI. Mr. Marquardt is the CEO of Global Kompass Strategies, serving as a global advisor to corporations around the world; and CEO of Epi One, a biotech company building a new cancer diagnosis platform. He previously led several companies in the technology and healthcare sectors, and served as President of the global risk management firm founded by former FBI Director Louis J. Freeh. Mr. Marquardt has served on the ACS and ACS CAN boards of directors since 2018 and 2014, respectively, and formerly as Chair of the former ACS South Atlantic Division Board and Chairman of the ACS National Board. He received ACS's St. George National Award in 2017, and was appointed in January 2022 by President Biden to serve on the U.S. Commission for the Preservation of America's Heritage Abroad. Mr. Marquardt received a bachelor's degree in medical biology, humanities from the University of New England; and a master's degree in chemistry from the University of Virginia. Ms. Mueller currently serves on the board of the International Society of Nurses in Cancer Care and has volunteered with ACS and ACS CAN for more than 35 years. She has held numerous leadership positions at ACS, including service as board President/Chair of the former Florida Division and Chair of the ACS board of directors. Ms. Mueller served 21 years as the Vice President and Chief Nursing Officer for the North Florida Regional Medical Center, and previously served on the boards of various organizations, including the Oncology Nursing Society Foundation, Samaritan Counseling Center of North Central Florida, the Oncology Nursing Certification Corporation, and the Oncology Nursing Society-Nominating Committee. Ms. Mueller received a master's degree in public health and a bachelor of science in nursing degree from the University of North Carolina at Chapel Hill. Mr. Reedy was CEO of ACS and ACS CAN from 2015 to 2021, following 15 years of volunteer leadership, including chairing the boards of directors for the organizations. He previously served as Worldwide Vice President, Government Affairs and Policy at Johnson & Johnson, President of Ortho Biotech, and in senior leadership roles at SmithKline Beecham and Centocor. He holds appointments to the board of directors of the Center for Global Health Innovation, the board of councilors for The Carter Center, the Georgia Tech Advisory Board, the Dean's Council at Emory University'sRollins School of Public Health, the Advisory Board for Emory University'sCenter for Ethics, and the MMM Tech Advisory Council. Mr. Reedy graduated from Emory & Henry College and received an honorary Doctorate of Humane Letters from Arcadia University. Mr. Youle is a civil practice attorney based in Denver, Colorado. He was a volunteer for ACS for nearly 30 years, serving at the local, state, regional and national levels. Mr. Youle served as Chairman of the Board of ACS's former Colorado and Rocky Mountain Divisions, its Great West Division and ACS CAN. He served on the ACS National Board since 2006 and was Chairman in 2015. Mr. Youle received a bachelor of science degree in finance from the Gies College of Business - University of Illinois Urbana-Champaign, and a Juris Doctor degree from University of Iowa College of Law.

Total avkastning till aktieägarna	-6.0%
Framtida utdelningsavkastning	n/a
Utdelningstillväxt	n/a
Nästa utbetalningsdag för utdelning	n/a
Ex utdelningsdag	n/a
Utdelning per aktie	n/a
Utdelningsandel	n/a

Segment	Utdelningsavkastning
Företag (ANIX)	n/a
Marknadens lägsta 25% (US)	1.4%
Marknad Topp 25% (US)	4.2%
Genomsnitt för branschen (Biotechs)	2.4%
Prognosanalytiker (ANIX) (upp till 3 år)	n/a

Uppgifter	Senast uppdaterad (UTC-tid)
Analys av företag	2026/06/17 22:31
Aktiekurs vid dagens slut	2026/06/17 00:00
Intäkter	2026/04/30
Årlig intjäning	2025/10/31

Paket	Uppgifter	Tidsram	Exempel US-källa
Företagets finansiella ställning	10 år	Resultaträkning Kassaflödesanalys Balansräkning	SEC Form 10-K SEC Form 10-Q
Analytikernas konsensusuppskattningar	+3 år	Prognos för finansiella poster Analytikernas prismål	Rapporter från analytiker Blue Matrix
Marknadspriser	30 år	Aktiekurser Utdelningar, splittar och åtgärder	ICE Marknadsdata SEC Form S-1
Ägarskap	10 år	Största aktieägare Insiderhandel	SEC Formulär 4 SEC Formulär 13D
Förvaltning	10 år	Ledningsgrupp Styrelse och verkställande direktörer	SEC Form 10-K SEC Form DEF 14A
Viktiga utvecklingstendenser	10 år	Företagsmeddelanden	SEC Formulär 8-K

Analytiker	Institution
Andrew D'Silva	B. Riley Securities, Inc.
Jason Kolbert	D. Boral Capital LLC.
Ilya Zubkov	Freedom Broker

Anixa Biosciences Utdelningar och återköp

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Viktig information

Senaste utdelnings- och återköpsuppdateringar

Anixa Biosciences, Inc. (NasdaqCM:ANIX) announces an Equity Buyback for $5 million worth of its shares.

Recent updates

CEO, Chairman & Co-Chair of CBAB recently bought US$53k worth of stock

Price target decreased by 9.1% to US$10.00

Anixa Biosciences Reports Updated Positive Survival Observations from Ongoing Phase 1 Trial of Lira-Cel Ovarian Cancer Car-T Therapy

Anixa Biosciences, Inc. Advances Breast Cancer Vaccine Toward Phase 2 After Positive Phase 1 Results

We're Not Very Worried About Anixa Biosciences' (NASDAQ:ANIX) Cash Burn Rate

Insufficient new directors

Anixa Biosciences Inc. Reports Encouraging Patient Survival Observations in Ovarian Cancer CAR-T Trial; Achieves Regulatory Approval Enabling Major Dose Escalation

New minor risk - Market cap size

Anixa Biosciences, Inc., Annual General Meeting, Mar 10, 2026

Anixa Biosciences, Inc. Announces World Health Organization Approval of International Non-Pproietary Name for Its Car-T Therapy

CEO, Chairman & Co-Chair of CBAB exercised options and sold US$193k worth of stock

Anixa Biosciences, Inc. Announces Completion of Final Patient Visit in Breast Cancer Vaccine Clinical Trial

New minor risk - Share price stability

Cleveland Clinic to Present Final Results of Phase 1 Clinical Trial for Anixa Biosciences' Breast Cancer Vaccine at 2025 San Antonio Breast Cancer Symposium

Anixa Biosciences and Moffitt Cancer Center Complete Dosing of Fourth Cohort in Ovarian Cancer CAR-T Clinical Trial

Anixa Biosciences, Inc Receives Notice of Allowance from Chinese National Intellectual Property Administration for Patent Covering Breast Cancer Vaccine Technology

Anixa Biosciences, Inc. Announces Treatment of Second Patient in Fourth Cohort of Ovarian Cancer CAR-T Clinical Trial

Anixa Biosciences Announces Commencement of US FDA Approved IND Transfer to Support Upcoming Phase 2 Breast Cancer Vaccine Trial

New minor risk - Market cap size

Anixa Biosciences Receives Notice of Allowance from Canadian Intellectual Property Office for Patent Covering Breast Cancer Vaccine Technology

Anixa Biosciences Initiates Dosing in Fourth Cohort in Its Ovarian Cancer Car-T Clinical Trial

Anixa Biosciences, Inc. Announces Completion of Enrollment in Phase 1 Trial of Breast Cancer Vaccine

Anixa Biosciences Receives Notice of Allowance from U.S. Patent and Trademark Office for Car-T Technology, Further Strengthening Its Robust Intellectual Property Portfolio

Anixa Biosciences Receives Notice of Allowance from USPTO for Ovarian Cancer Vaccine

Anixa Biosciences, Inc. and Moffitt Cancer Center Complete Dosing in Third Cohort in Ovarian Cancer CAR-T Clinical Trial

Anixa Biosciences Announces Approval of Protocol Amendment for Ovarian Cancer CAR-T Clinical Trial

Anixa Biosciences, Inc., Annual General Meeting, Mar 20, 2025

New minor risk - Share price stability

CEO, Chairman & Co-Chair of CBAB recently bought US$96k worth of stock

Are Investors Undervaluing Anixa Biosciences, Inc. (NASDAQ:ANIX) By 40%?

Anixa Biosciences, Inc Initiates Dosing in Third Cohort in its Ovarian Cancer CAR-T Clinical Trial

Anixa Biosciences and Cleveland Clinic Present New Updated Positive Data from Phase 1 Study of Breast Cancer Vaccine at the Society for Immunotherapy of Cancer Annual Meeting

Now 20% undervalued

Anixa Biosciences Announces Second Dose Administered to Patient in Ovarian Cancer CAR-T Clinical Trial

Anixa Biosciences Appoints Suyasha Gupta as Senior Director of Clinical Development

Anixa Biosciences, Inc. Announces Submission of Protocol Amendment for CAR-T Trial

New minor risk - Share price stability

We're Not Very Worried About Anixa Biosciences' (NASDAQ:ANIX) Cash Burn Rate

Lead Independent Director recently bought US$84k worth of stock

Anixa Biosciences Announces Japanese Patent on Breast Cancer Vaccine Technology

Anixa Biosciences, Inc. (NasdaqCM:ANIX) announces an Equity Buyback for $5 million worth of its shares.

Anixa Biosciences Treats Sixth Patient in its Ovarian Cancer CAR-T Clinical Trial

CEO, Chairman & Co-Chair of CBAB recently bought US$60k worth of stock

New major risk - Revenue and earnings growth

Anixa Biosciences, Inc. Commences Treatment of Fifth Patient in Ovarian Cancer CAR-T Clinical Trial

We're Hopeful That Anixa Biosciences (NASDAQ:ANIX) Will Use Its Cash Wisely

Anixa Biosciences Welcomes Sanjay Juneja to Its Cancer Business Advisory Board

CEO, Chairman & Co-Chair of CBAB recently bought US$97k worth of stock

New minor risk - Market cap size

New major risk - Revenue and earnings growth

Anixa Biosciences, Inc., Annual General Meeting, Mar 21, 2024

New minor risk - Share price stability

Anixa Biosciences, Inc. Announces Japanese Patent on Ovarian Cancer Vaccine Technology

We're Not Worried About Anixa Biosciences' (NASDAQ:ANIX) Cash Burn

Anixa Biosciences and Cleveland Clinic Present Positive New Data from Phase 1 Study of Breast Cancer Vaccine

Anixa Biosciences Announces European Patent on Ovarian Cancer Vaccine Technology

Anixa Biosciences, Inc. Appoints Mark A. Goldberg, Md, to Its Cancer Business Advisory Board

Anixa Biosciences, Inc. Completes Treatment of First Patient Cohort in Ovarian Cancer CAR-T Clinical Trial

We Think Anixa Biosciences (NASDAQ:ANIX) Can Easily Afford To Drive Business Growth

Anixa Biosciences, Inc. Establishes Cancer Business Advisory Board

Anixa Biosciences, Inc. Announces Opening of Enrollment for Keytruda® Arm in Ongoing Breast Cancer Vaccine Clinical Trial

Lead Independent Director exercised options to buy US$119k worth of stock.

Press Release: Anixa Biosciences Announces Notice of Allowance of Additional Patent on Ovarian Cancer Vaccine Technology

Is There An Opportunity With Anixa Biosciences, Inc.'s (NASDAQ:ANIX) 41% Undervaluation?

Now 38% undervalued after recent price drop

Price target increased by 11% to US$10.50

Anixa Biosciences, Inc., Annual General Meeting, Mar 09, 2023

Are Investors Undervaluing Anixa Biosciences, Inc. (NASDAQ:ANIX) By 36%?

Forecast to breakeven in 2024

Forecast to breakeven in 2024

Insufficient new directors

Insufficient new directors

Lead Independent Director exercised options to buy US$197k worth of stock.

We're Interested To See How Anixa Biosciences (NASDAQ:ANIX) Uses Its Cash Hoard To Grow