SLNC.F Stock Overview A biotechnology company, focuses on the discovery and development novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. More details
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Add noteSilence Therapeutics plc Competitors Price History & Performance
Summary of share price highs, lows and changes for Silence Therapeutics Historical stock prices Current Share Price US$2.00 52 Week High US$14.75 52 Week Low US$1.50 Beta 1.04 1 Month Change -63.64% 3 Month Change -70.15% 1 Year Change n/a 3 Year Change -72.03% 5 Year Change -62.26% Change since IPO 51.52%
Recent News & Updates
Silence Therapeutics plc Announces Additional Results from the Phase 1 Open Label Portion of the Sanreco Study of Divesiran Dec 10
Silence Therapeutics plc Presents Late-Breaking Phase 2 Zerlasiran Data at 2024 American Heart Association (AHA) Annual Meeting Nov 19
Silence Therapeutics plc Announces Executive Changes Aug 15
Silence Therapeutics plc Announces Positive Results from Ongoing SANRECO Phase 1 Study of Divesiran in Polycythemia Vera Patients Jun 28
Silence Therapeutics plc Announces Positive Topline 48-Week Data from Phase 2 Study of Zerlasiran in Patients with Elevated Lipoprotein(A) Jun 20
Silence Therapeutics plc Announces Retirement of Alistair Gray from Board of Directors, Effective May 1, 2024 Apr 30 See more updates
Silence Therapeutics plc Announces Additional Results from the Phase 1 Open Label Portion of the Sanreco Study of Divesiran Dec 10
Silence Therapeutics plc Presents Late-Breaking Phase 2 Zerlasiran Data at 2024 American Heart Association (AHA) Annual Meeting Nov 19
Silence Therapeutics plc Announces Executive Changes Aug 15
Silence Therapeutics plc Announces Positive Results from Ongoing SANRECO Phase 1 Study of Divesiran in Polycythemia Vera Patients Jun 28
Silence Therapeutics plc Announces Positive Topline 48-Week Data from Phase 2 Study of Zerlasiran in Patients with Elevated Lipoprotein(A) Jun 20
Silence Therapeutics plc Announces Retirement of Alistair Gray from Board of Directors, Effective May 1, 2024 Apr 30
Silence Therapeutics plc, Annual General Meeting, May 17, 2024 Apr 16
Silence Therapeutics plc Announces JAMA Publication of Additional Phase 1 Data for Zerlasiran in Subjects with Elevated Lipoprotein(a) Apr 10
Silence Therapeutics plc Announces Positive Topline 36-Week Data from Ongoing Phase 2 Study of Zerlasiran in Patients with High Lipoprotein(A) Mar 13
Silence Therapeutics plc to Report Q4, 2023 Results on Mar 13, 2024 Feb 29
Silence Therapeutics plc Announces Executive Changes Dec 01
Silence Therapeutics plc Announces Positive Topline Results from Phase 1 Multiple Dose Study of Zerlasiran in Subjects with High Lipoprotein(a) and Stable Atherosclerotic Cardiovascular Disease Nov 03
Silence Therapeutics plc Announces Retirement of Giles Campion as Chief Medical Officer, Head of Research & Development and Member of Board Jul 04
Silence Therapeutics plc Announces Executive Changes Feb 07
Silence Therapeutics plc Provides SLN360 and SLN124 Clinical Program Updates Jan 13
Silence Therapeutics plc Presents New Analysis from SLN360 Phase 1 Single Dose Study in High Lipoprotein(a) at the American Heart Association (AHA) 2022 Annual Meeting Nov 06
Silence Therapeutics Announces Preliminary Single Dose Results from SLN124 Phase 1 Study in Patients with Thalassemia Sep 30
Silence Therapeutics plc Announces FDA Fast Track Designation for SLN124, a Novel Investigational siRNA Therapy for the Treatment of Polycythemia Vera Sep 09
Silence Therapeutics plc, Annual General Meeting, Jun 14, 2022 May 17
Silence Therapeutics Announces Detailed Results From SLN360 Phase 1 Study in High Lipoprotein(a) Presented in Late Breaker at the American College of Cardiology (ACC.22) Annual Meeting Apr 04
Silence Therapeutics plc to Report Q4, 2021 Results on Mar 17, 2022 Mar 04 Silence Therapeutics plc Announces Executive Changes
Silence Therapeutics Announces Positive Topline Data in SLN360 Phase 1 Single-Ascending Dose Study in Healthy Adults with High Lipoprotein(a) Feb 10
Silence Therapeutics plc Presents Additional Positive Data from the SLN124 Healthy Volunteer Study Dec 13
Silence Therapeutics Updates on AIM Delisting Nov 27
Silence Therapeutics plc announced that it has received $40 million in funding from AstraZeneca PLC May 26
Silence Therapeutics plc Announces Positive Data from GEMINI Phase 1 Study of SLN124 in Healthy Volunteers May 19
Silence Therapeutics plc to Report Fiscal Year 2020 Results on Mar 30, 2021 Mar 01
Silence Therapeutics plc & Mallinckrodt plc Initiate Work on 3Rd Target Feb 27
Silence Therapeutics plc announced that it has received $45.499905 million in funding from a group of investors Feb 19
Silence Therapeutics plc Initiates Dosing in Phase 1 Clinical Trial of Sln360 for Cardiovascular Disease Due to High Lipoprotein(A) Feb 18
Silence Therapeutics Appoints Michael H. Davidson to Board of Directors Jan 07
Silence Therapeutics Appoints Craig Tooman as CFO Jan 06
Silence Therapeutics plc Presents Positive Pre-Clinical Data for SLN360 for the Treatment of Elevated Lipoprotein(a) At American Heart Association 2020 Nov 17
Silence Therapeutics plc Appoints Marie Wikström Lindholm as Senior Vice President, Molecular Design and Member of the Silence Executive Leadership Team Nov 03
Silence Therapeutics plc Announces Rob Quinn, the Current CFO Will Leave the Company in January 2021 Oct 08
Silence Therapeutics Appoints Mark Rothera as Chief Executive Officer Sep 15
Silence Therapeutics plc has completed a Follow-on Equity Offering in the amount of $311.826401 million. Sep 09
Silence Therapeutics plc to Report First Half, 2020 Results on Sep 14, 2020 Sep 02 Shareholder Returns SLNC.F US Biotechs US Market 7D 0% -3.6% -2.4% 1Y n/a -2.6% 23.4%
See full shareholder returns
Return vs Industry: Insufficient data to determine how SLNC.F performed against the US Biotechs industry .
Return vs Market: Insufficient data to determine how SLNC.F performed against the US Market .
Price Volatility Is SLNC.F's price volatile compared to industry and market? SLNC.F volatility SLNC.F Average Weekly Movement 35.3% Biotechs Industry Average Movement 10.8% Market Average Movement 6.3% 10% most volatile stocks in US Market 16.8% 10% least volatile stocks in US Market 3.1%
Stable Share Price: SLNC.F's share price has been volatile over the past 3 months compared to the US market.
Volatility Over Time: Insufficient data to determine SLNC.F's volatility change over the past year.
About the Company Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company’s mRNAi GalNAc Oligonucleotide Discovery platform consists of precision engineered product candidates designed to target specific disease-associated genes in the liver. The company develops Zerlasiran (SLN360), which is in phase 2 clinical trial for cardiovascular disease associated with elevated lipoprotein(a); and Divesiran (SLN124), an siRNA molecule that is in Phase I clinical trials for the treatment of genetic hematological conditions, including polycythemia vera.
Show more Silence Therapeutics plc Fundamentals Summary How do Silence Therapeutics's earnings and revenue compare to its market cap? SLNC.F fundamental statistics Market cap US$324.84m Earnings (TTM ) -US$74.02m Revenue (TTM ) US$20.43m
Earnings & Revenue Key profitability statistics from the latest earnings report (TTM) SLNC.F income statement (TTM ) Revenue UK£16.25m Cost of Revenue UK£8.97m Gross Profit UK£7.27m Other Expenses UK£66.14m Earnings -UK£58.86m
Last Reported Earnings
Sep 30, 2024
Earnings per share (EPS) -1.25 Gross Margin 44.78% Net Profit Margin -362.34% Debt/Equity Ratio 0%
How did SLNC.F perform over the long term?
See historical performance and comparison
Company Analysis and Financial Data Status Data Last Updated (UTC time) Company Analysis 2024/12/22 01:28 End of Day Share Price 2024/12/12 00:00 Earnings 2024/09/30 Annual Earnings 2023/12/31
Data Sources The data used in our company analysis is from S&P Global Market Intelligence LLC . The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
Package Data Timeframe Example US Source * Company Financials 10 years Income statement Cash flow statement Balance sheet Analyst Consensus Estimates +3 years Forecast financials Analyst price targets Market Prices 30 years Stock prices Dividends, Splits and Actions Ownership 10 years Top shareholders Insider trading Management 10 years Leadership team Board of directors Key Developments 10 years
* example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here .
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Analyst Sources Silence Therapeutics plc is covered by 14 analysts. 6 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
Analyst Institution null null BMO Capital Markets Equity Research Konstantinos Biliouris BMO Capital Markets Equity Research Thomas Shrader BTIG
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