Protalix BioTherapeutics, Inc.

NYSEAM:PLX Stock Report

Market Cap: US$170.8m

Protalix BioTherapeutics Management

Management criteria checks 4/4

Protalix BioTherapeutics' CEO is Dror Bashan, appointed in Jun 2019, has a tenure of 6.83 years. total yearly compensation is $1.53M, comprised of 24.5% salary and 75.5% bonuses, including company stock and options. directly owns 3.14% of the company’s shares, worth $5.37M. The average tenure of the management team and the board of directors is 5.3 years and 6.3 years respectively.

Key information

Dror Bashan

Chief executive officer

US$1.5m

Total compensation

CEO salary percentage24.49%
CEO tenure6.8yrs
CEO ownership3.1%
Management average tenure5.3yrs
Board average tenure6.3yrs

Recent management updates

Recent updates

PLX: New Dosing Approval And 2026 Revenue Outlook Will Support Upside

Analysts now set Protalix BioTherapeutics' price target at $11.00. The unchanged level reflects only minimal tweaks to inputs such as the discount rate, long term revenue growth, profit margin assumptions and future P/E expectations.

PLX: New Dosing Approval And 2026 Revenue Outlook Will Support Upside

Analysts have maintained their $11.00 price target for Protalix BioTherapeutics, citing relatively stable assumptions around fair value, discount rate, revenue growth, profit margin and future P/E as the basis for keeping their outlook unchanged. What's in the News The European Commission approves a 2 mg/kg every four weeks dosing regimen for pegunigalsidase alfa in adults with Fabry disease who are stable on enzyme replacement therapy, extending the infusion interval from every two weeks to every four weeks (Key Developments).

PLX: New Dosing Approval And 2026 Outlook Will Support Undervalued Upside

Analysts kept their $11.00 price target on Protalix BioTherapeutics unchanged, highlighting revised assumptions for revenue growth, profit margins, the discount rate and future P/E as key drivers behind their updated model. What's in the News Protalix BioTherapeutics issued 2026 total revenue guidance of approximately $78.0 million to $83.0 million, which includes a $25.0 million milestone payment from Chiesi tied to regulatory progress for Elfabrio (company guidance).

PLX: Extended Fabry Dosing Will Support Undervalued Long Term Outlook

Analysts have reiterated an $11.00 price target for Protalix BioTherapeutics, citing only slight tweaks to model inputs such as the discount rate, long-term revenue growth, profit margins, and future P/E assumptions rather than any major shift in their overall view. What's in the News Chiesi Global Rare Diseases and Protalix BioTherapeutics reported that the European Medicines Agency's Committee for Medicinal Product for Human Use issued a positive opinion recommending approval of a 2 mg/kg every 4 weeks dosing regimen of pegunigalsidase alfa for adult Fabry patients who are stable on enzyme replacement therapy (Key Developments).

PLX: Fabry Dosing Extension Will Support Undervalued Long Term Outlook

Analysts are maintaining their $11.00 price target for Protalix BioTherapeutics while slightly refining core modeling inputs such as the discount rate, long term revenue growth, profit margin and future P/E assumptions to better align with their updated risk and earnings outlook. What's in the News CHMP of the EMA issued a positive opinion recommending approval of a 2 mg/kg every 4 weeks dosing regimen for pegunigalsidase alfa in adult Fabry disease patients who are stable on enzyme replacement therapy, potentially giving eligible patients a longer interval between infusions (Product related announcement).

PLX: Renal ASO Pipeline And Fabry Dosing Expansion Will Drive Upside

Analysts have maintained their price target for Protalix BioTherapeutics at US$11.00, citing a combination of updated assumptions regarding the discount rate, revenue growth, profit margins, and a higher future P/E multiple as reasons to keep their existing valuation view. What's in the News Chiesi Global Rare Diseases and Protalix BioTherapeutics reported that the EMA's Committee for Medicinal Products for Human Use issued a positive opinion recommending approval of a 2 mg/kg every 4 weeks dosing regimen of pegunigalsidase alfa for adult Fabry patients who are stable on enzyme replacement therapy, aiming to extend time between infusions so patients can focus more on daily life (Key Developments).

PLX: Renal ASO Collaboration Will Drive Next Phase Of Upside Potential

Analysts have maintained their US$11.00 price target for Protalix BioTherapeutics, citing only slight adjustments to their discount rate, long term revenue growth, profit margin assumptions and future P/E outlook, rather than any major shift in their thesis. What's in the News Protalix BioTherapeutics and Secarna Pharmaceuticals entered a collaboration and option agreement to discover antisense oligonucleotide therapies targeting rare renal indications, with Secarna using its OligoCreator platform to design and profile candidates and Protalix selecting the biological targets (Key Developments).

PLX: Renal Collaboration Agreement Will Drive Next Phase Of Upside Potential

Analysts have maintained their fair value estimate for Protalix BioTherapeutics at US$11.00. This reflects only minor adjustments to assumptions around discount rate, revenue growth, profit margins and future P/E that do not materially change their overall view.

PLX: European Label Expansion Review Will Drive Next Phase Of Upside Potential

Analysts have nudged their price target on Protalix BioTherapeutics slightly higher to $11.00, reflecting marginal adjustments to discount rate, long term growth, and profitability assumptions, while maintaining a broadly consistent valuation framework. What's in the News Chiesi Global Rare Diseases and Protalix BioTherapeutics requested re examination of the EMA CHMP negative opinion on adding a once every 4 weeks 2 mg/kg Elfabrio dosing regimen to the currently approved every 2 weeks regimen, seeking broader label flexibility in Europe (Key Developments) Safety data from Elfabrio clinical trials highlighted hypersensitivity reactions in 14 percent of treated patients and anaphylaxis in 3 percent, underscoring the need for careful infusion monitoring and potential dose adjustments (Key Developments) Additional clinical observations included infusion associated reactions in 29 percent of Elfabrio patients and a reported case of membranoproliferative glomerulonephritis, prompting recommendations to monitor renal function and infusion related symptoms (Key Developments) Protalix BioTherapeutics was added to the S&P Global BMI Index, potentially increasing its visibility and accessibility to global institutional investors (Key Developments) Valuation Changes Fair value estimate maintained at $11.00 per share, indicating no change to the analyst target price.

PLX: European Regulatory Review Will Unlock Next Phase Of Upside Potential

Analysts have lowered their price target for Protalix BioTherapeutics from $12.50 to $11.00, citing a slight reduction in expected revenue growth and profit margins. What's in the News Protalix BioTherapeutics and Chiesi Global Rare Diseases have requested a re-examination of the negative opinion by the European Medicines Agency regarding the new dosing regimen for Elfabrio.

PLX: European Review Process Will Drive Next Phase Of Momentum

Analysts have lowered their price target for Protalix BioTherapeutics from $14.00 to $12.50. They cite more conservative expectations regarding revenue growth and profit margins.
User avatar

Protalix BioTherapeutics aims for $3.20 by year-end amidst strong revenue growth

As of right now the stock as a current yield of about 2.42%, with a return on equity of about 6.79%. So a bit off of my goals of at least 5% and 10%. However over the last 3 years revenue has grown on
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PRX-115 Trials And Elfabrio Launch Will Open Future Markets

Successful Phase II trials and Chiesi's involvement with Elfabrio could drive growth through new marketable products and increased market adoption.

Analysts Expect Protalix BioTherapeutics, Inc. (NYSEMKT:PLX) To Breakeven Soon

Feb 22
Analysts Expect Protalix BioTherapeutics, Inc. (NYSEMKT:PLX) To Breakeven Soon

Have Insiders Been Buying Protalix BioTherapeutics, Inc. (NYSEMKT:PLX) Shares This Year?

Jan 14
Have Insiders Been Buying Protalix BioTherapeutics, Inc. (NYSEMKT:PLX) Shares This Year?

Could The Protalix BioTherapeutics, Inc. (NYSEMKT:PLX) Ownership Structure Tell Us Something Useful?

Dec 10
Could The Protalix BioTherapeutics, Inc. (NYSEMKT:PLX) Ownership Structure Tell Us Something Useful?

CEO Compensation Analysis

How has Dror Bashan's remuneration changed compared to Protalix BioTherapeutics's earnings?
DateTotal CompensationSalaryCompany Earnings
Dec 31 2025n/an/a

-US$7m

Sep 30 2025n/an/a

US$5m

Jun 30 2025n/an/a

US$6m

Mar 31 2025n/an/a

US$4m

Dec 31 2024US$2mUS$374k

US$3m

Sep 30 2024n/an/a

-US$10m

Jun 30 2024n/an/a

-US$15m

Mar 31 2024n/an/a

US$7m

Dec 31 2023US$3mUS$357k

US$8m

Sep 30 2023n/an/a

US$11m

Jun 30 2023n/an/a

US$9m

Mar 31 2023n/an/a

-US$16m

Dec 31 2022US$1mUS$360k

-US$15m

Sep 30 2022n/an/a

-US$18m

Jun 30 2022n/an/a

-US$18m

Mar 31 2022n/an/a

-US$24m

Dec 31 2021US$1mUS$374k

-US$28m

Sep 30 2021n/an/a

-US$21m

Jun 30 2021n/an/a

-US$21m

Mar 31 2021n/an/a

-US$14m

Dec 31 2020US$1mUS$352k

-US$7m

Sep 30 2020n/an/a

-US$7m

Jun 30 2020n/an/a

-US$6m

Mar 31 2020n/an/a

-US$9m

Dec 31 2019US$566kUS$175k

-US$18m

Compensation vs Market: Dror's total compensation ($USD1.53M) is about average for companies of similar size in the US market ($USD1.56M).

Compensation vs Earnings: Dror's compensation has been consistent with company performance over the past year.


CEO

Dror Bashan (58 yo)

6.8yrs
Tenure
US$1,527,792
Compensation

Mr. Dror Bashan has been President, Chief Executive Officer and Director of Protalix BioTherapeutics, Inc. since June 30, 2019. He has experience in the pharmaceutical industry with roles ranging from busi...


Leadership Team

NamePositionTenureCompensationOwnership
Dror Bashan
President6.8yrsUS$1.53m3.14%
$ 5.4m
Yaron Naos
Senior Vice President of Operations7.9yrsUS$639.96k0.29%
$ 493.8k
Gilad Mamlok
Senior VP & CFOless than a yearno datano data
Yael Fellous
Vice President of Human Resources3.7yrsno datano data
5.3yrs
Average Tenure
58yo
Average Age

Experienced Management: PLX's management team is seasoned and experienced (5.3 years average tenure).


Board Members

NamePositionTenureCompensationOwnership
Dror Bashan
President6.8yrsUS$1.53m3.14%
$ 5.4m
Amos Shalev
Independent Director17.8yrsUS$45.00k0.0093%
$ 15.9k
Aharon Schwartz
Independent Director11.4yrsUS$45.00k0.39%
$ 658.3k
Gwen A. Melincoff
Independent Director6.3yrsUS$45.00k0.0093%
$ 15.9k
Charles Arntzen
Member of Scientific Advisory Board9.8yrsno datano data
Alexander Levitzki
Member of Scientific Advisory Boardno datano datano data
Shmuel Ben-Zvi
Independent Director3.8yrsUS$33.75k0.0093%
$ 15.9k
Roger Kornberg
Chairman of Scientific Advisory Boardno dataUS$55.00kno data
Eliot Forster
Independent Chairman2.6yrsUS$70.00k0.0093%
$ 15.9k
Pol Boudes
Independent Director6.3yrsUS$46.35k0.0094%
$ 16.0k
Christian Elze
Directorless than a yearno data0.0093%
$ 15.9k
6.3yrs
Average Tenure
72yo
Average Age

Experienced Board: PLX's board of directors are considered experienced (6.3 years average tenure).


Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/04/29 17:14
End of Day Share Price 2026/04/29 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Industry and Sector Metrics

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Analyst Sources

Protalix BioTherapeutics, Inc. is covered by 8 analysts. 2 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Ritu BaralCanaccord Genuity
Raghuram SelvarajuH.C. Wainwright & Co.
Peter WelfordJefferies LLC