Vertex Pharmaceuticals Incorporated

NasdaqGS:VRTX Stock Report

Market Cap: US$102.3b

Vertex Pharmaceuticals Valuation

Is VRTX undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

4/6

Valuation Score 4/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Sales vs Peers

  • Price-To-Sales vs Industry

  • Price-To-Sales vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of VRTX when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: VRTX ($397.27) is trading below our estimate of fair value ($881.89)

Significantly Below Fair Value: VRTX is trading below fair value by more than 20%.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for VRTX?

Key metric: As VRTX is unprofitable we use its Price-To-Sales Ratio for relative valuation analysis.

The above table shows the Price to Sales ratio for VRTX. This is calculated by dividing VRTX's market cap by their current revenue.
What is VRTX's PS Ratio?
PS Ratio9.6x
SalesUS$10.63b
Market CapUS$102.31b

Price to Sales Ratio vs Peers

How does VRTX's PS Ratio compare to its peers?

The above table shows the PS ratio for VRTX vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PSEstimated GrowthMarket Cap
Peer Average8.2x
GILD Gilead Sciences
4.1x2.5%US$115.4b
AMGN Amgen
4.4x2.3%US$141.6b
REGN Regeneron Pharmaceuticals
5.5x7.0%US$75.5b
SGEN Seagen
18.8x22.6%US$43.2b
VRTX Vertex Pharmaceuticals
9.6x8.2%US$102.3b

Price-To-Sales vs Peers: VRTX is expensive based on its Price-To-Sales Ratio (9.6x) compared to the peer average (8.2x).

Price to Sales Ratio vs Industry

How does VRTX's PS Ratio compare vs other companies in the US Biotechs Industry?

134 CompaniesPrice / SalesEstimated GrowthMarket Cap
BIIB Biogen
2.2x1.3%US$21.34b
MRNA Moderna
3x5.8%US$15.16b
INCY Incyte
3.3x8.9%US$13.26b
ALKS Alkermes
3.2x-0.7%US$4.81b
VRTX 9.6xIndustry Avg. 9.9xNo. of Companies134PS01632486480+
134 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Sales vs Industry: VRTX is good value based on its Price-To-Sales Ratio (9.6x) compared to the US Biotechs industry average (9.9x).

Price to Sales Ratio vs Fair Ratio

What is VRTX's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

VRTX PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio9.6x
Fair PS Ratio8.4x

Price-To-Sales vs Fair Ratio: VRTX is expensive based on its Price-To-Sales Ratio (9.6x) compared to the estimated Fair Price-To-Sales Ratio (8.4x).

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst VRTX forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$397.27
US$498.24
+25.4%
14.3%US$602.00US$325.00n/a30
Dec ’25US$468.13
US$518.33
+10.7%
12.6%US$602.00US$325.00n/a30
Nov ’25US$471.12
US$508.70
+8.0%
13.1%US$600.00US$325.00n/a31
Oct ’25US$469.76
US$508.23
+8.2%
13.5%US$600.00US$325.00n/a29
Sep ’25US$495.89
US$509.82
+2.8%
13.7%US$600.00US$325.00n/a29
Aug ’25US$505.78
US$483.96
-4.3%
12.7%US$589.00US$325.00n/a30
Jul ’25US$471.25
US$468.27
-0.6%
12.8%US$577.00US$325.00n/a29
Jun ’25US$455.34
US$463.53
+1.8%
12.5%US$577.00US$325.00n/a28
May ’25US$402.14
US$459.72
+14.3%
12.2%US$574.00US$325.00n/a29
Apr ’25US$420.48
US$461.10
+9.7%
12.4%US$574.00US$325.00n/a29
Mar ’25US$432.76
US$461.41
+6.6%
12.6%US$578.00US$325.00n/a28
Feb ’25US$433.87
US$436.63
+0.6%
13.9%US$559.00US$314.00n/a27
Jan ’25US$406.89
US$409.39
+0.6%
11.0%US$500.00US$314.00n/a28
Dec ’24US$351.16
US$395.90
+12.7%
9.2%US$456.00US$314.00US$468.1328
Nov ’24US$369.33
US$386.90
+4.8%
9.4%US$456.00US$314.00US$471.1228
Oct ’24US$347.74
US$384.45
+10.6%
9.3%US$456.00US$314.00US$469.7627
Sep ’24US$351.10
US$384.26
+9.4%
9.4%US$456.00US$314.00US$495.8927
Aug ’24US$347.74
US$379.81
+9.2%
9.9%US$456.00US$306.00US$505.7827
Jul ’24US$351.91
US$375.26
+6.6%
9.3%US$456.00US$306.00US$471.2527
Jun ’24US$323.62
US$372.14
+15.0%
10.0%US$456.00US$305.00US$455.3428
May ’24US$345.00
US$337.23
-2.3%
9.5%US$439.00US$280.00US$402.1426
Apr ’24US$315.07
US$334.11
+6.0%
9.5%US$440.00US$280.00US$420.4826
Mar ’24US$291.23
US$332.40
+14.1%
9.7%US$440.00US$280.00US$432.7626
Feb ’24US$317.27
US$329.37
+3.8%
10.3%US$440.00US$280.00US$433.8726
Jan ’24US$288.78
US$323.74
+12.1%
10.8%US$440.00US$265.00US$406.8925
Dec ’23US$320.76
US$323.74
+0.9%
10.8%US$440.00US$265.00US$351.1625

Analyst Forecast: Target price is more than 20% higher than the current share price and analysts are within a statistically confident range of agreement.

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2024/12/22 02:28
End of Day Share Price 2024/12/20 00:00
Earnings2024/09/30
Annual Earnings2023/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on .

Analyst Sources

Vertex Pharmaceuticals Incorporated is covered by 77 analysts. 33 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Jasper HellwegArgus Research Company
Brian SkorneyBaird
Ishan MajumdarBaptista Research