Stoke Therapeutics, Inc.

NasdaqGS:STOK Stock Report

Market Cap: US$2.0b

Stoke Therapeutics Future Growth

Future criteria checks 2/6

Stoke Therapeutics is forecast to grow earnings and revenue by 49.3% and 55.9% per annum respectively. EPS is expected to grow by 48.3% per annum. Return on equity is forecast to be -28.4% in 3 years.

Key information

49.3%

Earnings growth rate

48.29%

EPS growth rate

Biotechs earnings growth25.3%
Revenue growth rate55.9%
Future return on equity-28.45%
Analyst coverage

Good

Last updated09 Jul 2026

Recent future growth updates

Analysis Article May 11

Stoke Therapeutics, Inc. (NASDAQ:STOK) Analysts Are Pretty Bullish On The Stock After Recent Results

As you might know, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) just kicked off its latest quarterly results with some very...

Recent updates

Narrative Update Jul 10

STOK: Phase 3 Dravet Data And NDA Timeline Will Drive Upside

Analysts have raised their fair value estimate for Stoke Therapeutics from $39.00 to $60.00, citing updated assumptions related to revenue growth, profitability, and a lower projected future P/E multiple. What’s in the News for Stoke Therapeutics Stoke Therapeutics has completed enrollment of 162 patients in the Phase 3 EMPEROR study of zorevunersen in Dravet syndrome.
Narrative Update Jun 26

None

Analysts have lifted their price target for Stoke Therapeutics from $34.25 to $45.10, citing updated assumptions around revenue growth, profitability, and a lower projected future P/E multiple as key drivers of the change. What’s in the News for Stoke Therapeutics No recent company specific news for Stoke Therapeutics was identified in the provided sources.
Analysis Article May 11

Stoke Therapeutics, Inc. (NASDAQ:STOK) Analysts Are Pretty Bullish On The Stock After Recent Results

As you might know, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) just kicked off its latest quarterly results with some very...
New Narrative May 11

Phase III Trial And Payer Risks Will Shape Dravet Treatment Prospects

Catalysts About Stoke Therapeutics Stoke Therapeutics is a biotechnology company focused on RNA-based medicines, including zorevunersen for Dravet syndrome. What are the underlying business or industry changes driving this perspective?
Seeking Alpha May 01

Stoke Therapeutics: Zorevunersen Has Disease-Modifying Potential In Dravet Syndrome

Summary I initiate Stoke Therapeutics with a Buy rating, driven by late-stage progress for zorevunersen in SCN1A Dravet Syndrome. STOK's phase 3 EMPEROR trial for zorevunersen targets mid-2027 data and a rolling NDA submission in the first half of 2027. Three-year open-label data show durable seizure reduction and functional improvement, supporting disease-modifying potential for zorevunersen. STOK's $390.9M cash position, Biogen partnership, and low burn rate provide runway into mid-2028, mitigating near-term financing risk. Read the full article on Seeking Alpha
Analysis Article Jan 12

Newsflash: Stoke Therapeutics, Inc. (NASDAQ:STOK) Analysts Have Been Trimming Their Revenue Forecasts

The analysts covering Stoke Therapeutics, Inc. ( NASDAQ:STOK ) delivered a dose of negativity to shareholders today, by...
Analysis Article Dec 05

Stoke Therapeutics, Inc.'s (NASDAQ:STOK) Shares Bounce 36% But Its Business Still Trails The Industry

Despite an already strong run, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares have been powering on, with a gain of...
Analysis Article Oct 09

Stoke Therapeutics, Inc. (NASDAQ:STOK) Held Back By Insufficient Growth Even After Shares Climb 39%

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares have continued their recent momentum with a 39% gain in the last month...
Analysis Article Aug 25

Improved Revenues Required Before Stoke Therapeutics, Inc. (NASDAQ:STOK) Stock's 49% Jump Looks Justified

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares have continued their recent momentum with a 49% gain in the last month...
Analysis Article Aug 15

Stoke Therapeutics, Inc. (NASDAQ:STOK) Shares Could Be 25% Above Their Intrinsic Value Estimate

NasdaqGS:STOK 1 Year Share Price vs Fair Value Explore Stoke Therapeutics's Fair Values from the Community and select...
Analysis Article May 20

Stoke Therapeutics, Inc.'s (NASDAQ:STOK) Shares Bounce 28% But Its Business Still Trails The Industry

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders would be excited to see that the share price has had a great...
Analysis Article Apr 16

Analysts Are More Bearish On Stoke Therapeutics, Inc. (NASDAQ:STOK) Than They Used To Be

Market forces rained on the parade of Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders today, when the analysts...
Analysis Article Apr 05

Stoke Therapeutics, Inc.'s (NASDAQ:STOK) 27% Dip Still Leaving Some Shareholders Feeling Restless Over Its P/SRatio

To the annoyance of some shareholders, Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shares are down a considerable 27% in...
Analysis Article Feb 26

We're Hopeful That Stoke Therapeutics (NASDAQ:STOK) Will Use Its Cash Wisely

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Seeking Alpha Feb 16

Stoke Therapeutics: A Pivotal Moment For This RNA Pioneer

Summary Stoke Therapeutics' RNA-based treatments for severe neurological and ophthalmic disorders, particularly zorevunersen for Dravet syndrome, show potential for long-term value beyond a single drug. Financials reveal high R&D spending and cash burn, but revenue growth from Acadia Pharmaceuticals collaboration suggests early monetization and potential non-dilutive funding. The Phase 3 EMPEROR study for zorevunersen is critical, with regulatory alignment and promising early data, but execution and long-term safety monitoring remain challenges. Stoke's broader pipeline, including treatments for SYNGAP1-related disorders, Rett syndrome, and Autosomal Dominant Optic Atrophy, could expand its market potential if RNA modulation proves broadly effective. Read the full article on Seeking Alpha
Analysis Article Nov 08

Earnings Update: Stoke Therapeutics, Inc. (NASDAQ:STOK) Just Reported And Analysts Are Trimming Their Forecasts

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) just released its third-quarter report and things are looking bullish. Results...
Analysis Article Nov 06

Industry Analysts Just Made A Huge Upgrade To Their Stoke Therapeutics, Inc. (NASDAQ:STOK) Revenue Forecasts

Stoke Therapeutics, Inc. ( NASDAQ:STOK ) shareholders will have a reason to smile today, with the analysts making...
Seeking Alpha Sep 07

Stoke Therapeutics: The First Gene Therapy For Dravet Syndrome

Summary STOK's zorevunersen shows strong efficacy in reducing seizures but has safety concerns, particularly elevated CSF protein levels, needing further monitoring. Dravet Syndrome market potential is significant, with 35,000 patients in key regions and existing treatments costing up to $96,000 annually. STOK has a solid cash runway for 7-8 quarters, with a Phase 3 trial expected to start soon, aiming for topline data by mid-2026. Despite recent stock gains, I may consider investing when Phase 3 trial enrollment is announced, given the promising genetic approach to Dravet Syndrome. Read the full article on Seeking Alpha

Earnings and Revenue Growth Forecasts

NasdaqGS:STOK - Analysts future estimates and past financials data (USD Millions)
DateRevenueEarningsFree Cash FlowCash from OpAvg. No. Analysts
12/31/2028122-148-50-988
12/31/202746-212-187-19610
12/31/202626-211-206-19411
3/31/202632-170-148-147N/A
12/31/2025184-74546N/A
9/30/2025206415253N/A
6/30/2025200526162N/A
3/31/2025191506970N/A
12/31/202437-89-87-87N/A
9/30/202417-105-85-84N/A
6/30/202415-104-81-80N/A
3/31/20248-109-86-84N/A
12/31/20239-105-83-81N/A
9/30/20239-103-85-83N/A
6/30/20239-105-91-88N/A
3/31/202315-99-89-86N/A
12/31/202212-101-36-32N/A
9/30/20229-100-30-26N/A
6/30/20226-96-20-18N/A
3/31/20223-94-16-14N/A
12/31/2021N/A-86-68-67N/A
9/30/2021N/A-76-63-62N/A
6/30/2021N/A-67-59-58N/A
3/31/2021N/A-58-52-52N/A
12/31/2020N/A-52-43-42N/A
9/30/2020N/A-48-43-41N/A
6/30/2020N/A-43-41-39N/A
3/31/2020N/A-38-37-35N/A
12/31/2019N/A-32N/A-31N/A
9/30/2019N/A-26N/A-24N/A
6/30/2019N/A-21N/A-19N/A
3/31/2019N/A-16N/A-16N/A
12/31/2018N/A-13N/A-11N/A

Analyst Future Growth Forecasts

Earnings vs Savings Rate: STOK is forecast to remain unprofitable over the next 3 years.

Earnings vs Market: STOK is forecast to remain unprofitable over the next 3 years.

High Growth Earnings: STOK is forecast to remain unprofitable over the next 3 years.

Revenue vs Market: STOK's revenue (55.9% per year) is forecast to grow faster than the US market (12.9% per year).

High Growth Revenue: STOK's revenue (55.9% per year) is forecast to grow faster than 20% per year.


Earnings per Share Growth Forecasts


Future Return on Equity

Future ROE: STOK is forecast to be unprofitable in 3 years.


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/10 08:59
End of Day Share Price 2026/07/10 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Stoke Therapeutics, Inc. is covered by 21 analysts. 11 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Gregory HarrisonBofA Global Research
Thomas ShraderBTIG
Michelle GilsonCanaccord Genuity