Stock Analysis

How Does Wolfe Research’s Support Shape Soleno Therapeutics’ (SLNO) Credibility Amid Heightened Scrutiny?

  • Wolfe Research recently initiated coverage on Soleno Therapeutics, providing a positive outlook for ViCAT XR after concerns were raised over its safety and commercial prospects.
  • This coverage comes in the wake of both a short seller report and ongoing legal investigations, reflecting heightened scrutiny and contrasting expert perspectives for investors.
  • We’ll explore how Wolfe Research’s assessment of ViCAT XR’s insurance access and patient growth prospects shapes the company’s investment narrative.

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What Is Soleno Therapeutics' Investment Narrative?

For anyone considering Soleno Therapeutics as a potential investment, the story increasingly revolves around the ongoing commercialization of VYKAT XR and the company’s ability to navigate recent scrutiny. The core narrative is still focused on VYKAT XR’s adoption among patients with Prader-Willi Syndrome and insurance coverage progress, with Wolfe Research recently reaffirming positive expectations despite short-term hurdles. However, the latest investigations into Soleno’s disclosures, following a sharp price decline and a high-profile short seller report, mark a clear shift in the immediate risk landscape. Where earlier analysis pointed mainly to revenue growth potential and profitability milestones, current catalysts now rest more on restoring investor confidence, managing regulatory scrutiny, and stabilizing prescriber and patient sentiment. As these new challenges unfold, the material impact of litigation and perception risks could potentially outweigh near-term commercial gains.
In contrast to coverage gains, unresolved questions around disclosure practices should not be overlooked by investors.

Soleno Therapeutics' shares have been on the rise but are still potentially undervalued. Find out how large the opportunity might be.

Exploring Other Perspectives

SLNO Community Fair Values as at Dec 2025
SLNO Community Fair Values as at Dec 2025
The Simply Wall St Community has contributed three fair value estimates for Soleno Therapeutics, ranging from US$43 to a very large US$430 per share. These wide differences reflect sharply contrasting growth outlooks among retail investors. With regulatory scrutiny now in focus, a single catalyst or risk has the potential to quickly shift sentiment and drive meaningful share price moves.

Explore 3 other fair value estimates on Soleno Therapeutics - why the stock might be worth over 8x more than the current price!

Build Your Own Soleno Therapeutics Narrative

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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About NasdaqCM:SLNO

Soleno Therapeutics

A clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases.

High growth potential with adequate balance sheet.

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