Septerna's earnings have been declining at an average annual rate of -43.9%, while the Pharmaceuticals industry saw earnings growing at 8.2% annually. Revenues have been growing at an average rate of 7295.6% per year.
How Septerna makes and spends money. Based on latest reported earnings, on an LTM basis.
Earnings and Revenue History
NasdaqGM:SEPN Revenue, expenses and earnings (USD Millions)
Date
Revenue
Earnings
G+A Expenses
R&D Expenses
31 Mar 26
72
-36
33
108
31 Dec 25
46
-49
29
98
30 Sep 25
22
-59
26
85
30 Jun 25
1
-88
24
79
31 Mar 25
1
-79
21
71
31 Dec 24
1
-72
17
65
30 Sep 24
1
-20
14
56
30 Jun 24
1
-10
12
48
31 Mar 24
0
-4
10
41
31 Dec 23
0
1
10
36
Quality Earnings: SEPN is currently unprofitable.
Growing Profit Margin: SEPN is currently unprofitable.
Free Cash Flow vs Earnings Analysis
Past Earnings Growth Analysis
Earnings Trend: SEPN is unprofitable, and losses have increased over the past 5 years at a rate of 43.9% per year.
Accelerating Growth: Unable to compare SEPN's earnings growth over the past year to its 5-year average as it is currently unprofitable
Earnings vs Industry: SEPN is unprofitable, making it difficult to compare its past year earnings growth to the Pharmaceuticals industry (-5%).
Return on Equity
High ROE: SEPN has a negative Return on Equity (-9.52%), as it is currently unprofitable.
Return on Assets
Return on Capital Employed
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Company Analysis and Financial Data Status
Data
Last Updated (UTC time)
Company Analysis
2026/05/12 23:48
End of Day Share Price
2026/05/12 00:00
Earnings
2026/03/31
Annual Earnings
2025/12/31
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
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Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
Septerna, Inc. is covered by 9 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.