Regulus Therapeutics Inc.

NasdaqCM:RGLS Stock Report

Market Cap: US$617.0m

This company has been acquired

The company may no longer be operating, as it has been acquired. Find out why through their latest events.

Regulus Therapeutics Management

Management criteria checks 3/4

Regulus Therapeutics' CEO is Jay Hagan, appointed in May 2017, has a tenure of 8.08 years. total yearly compensation is $3.88M, comprised of 16.5% salary and 83.5% bonuses, including company stock and options. directly owns 0.38% of the company’s shares, worth $2.37M. The average tenure of the management team and the board of directors is 5.8 years and 8 years respectively.

Key information

Jay Hagan

Chief executive officer

US$3.9m

Total compensation

CEO salary percentage16.50%
CEO tenure8.1yrs
CEO ownership0.4%
Management average tenure5.8yrs
Board average tenure8yrs

Recent management updates

Recent updates

Analysis Article • Sep 28

Companies Like Regulus Therapeutics (NASDAQ:RGLS) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Seeking Alpha • Sep 12

Regulus surges 15% after Phase 1 data for kidney disease candidate

The shares of clinical-stage biotech Regulus Therapeutics Inc. (NASDAQ:RGLS) climbed ~15% in the pre-market trading Monday after the company announced topline data from its Phase 1 Single-Ascending Dose (SAD) trial for kidney disease candidate RGLS8429. RGLS8429, designed to target Autosomal Dominant Polycystic Kidney Disease (ADPKD), belongs to a drug class known as oligonucleotides. The topline safety and pharmacokinetics data from the study involving healthy volunteers indicated that RGLS8429 was well-tolerated with no serious adverse events, RGLS said. Among 32 patients who received the therapy, there were nine adverse events, out of which only one (sinus infection) was found to be moderate in severity. With the data update from the SAD portion of the study, the company announced the launch of the Phase 1b Multiple Ascending Dose (MAD) study for the candidate, which involves ADPKD patients. The topline data from the first cohort of patients are expected in 1H 2023. Read: Seeking Alpha contributor Bret Jensen takes a deep dive into RGLS with a Hold rating on the stock.
Seeking Alpha • Aug 11

Regulus Therapeutics GAAP loss per share narrows

Regulus Therapeutics press release (NASDAQ:RGLS): Q2 GAAP EPS of -$0.50 (vs. -$0.78 Y/Y). As of Jun. 30, Regulus had $47.5M in cash, cash equivalents and marketable securities.
Analysis Article • Oct 12

Does Regulus Therapeutics (NASDAQ:RGLS) Have A Healthy Balance Sheet?

Howard Marks put it nicely when he said that, rather than worrying about share price volatility, 'The possibility of...
Seeking Alpha • Aug 03

The Read On Regulus Therapeutics

Today, we take an in-depth look at Regulus Therapeutics. This small cap developmental firm is focused on microRNA therapeutics and has multiple 'shots on goal' in its pipeline. A full investment analysis follows in the paragraphs below.
Analysis Article • Jun 09

We Think Shareholders Are Less Likely To Approve A Large Pay Rise For Regulus Therapeutics Inc.'s (NASDAQ:RGLS) CEO For Now

Shareholders of Regulus Therapeutics Inc. ( NASDAQ:RGLS ) will have been dismayed by the negative share price return...
Analysis Article • Mar 13

Auditors Are Concerned About Regulus Therapeutics (NASDAQ:RGLS)

Unfortunately for shareholders, when Regulus Therapeutics Inc. ( NASDAQ:RGLS ) reported results for the period to...
Analysis Article • Mar 10

Introducing Regulus Therapeutics (NASDAQ:RGLS), The Stock That Zoomed 101% In The Last Year

Regulus Therapeutics Inc. ( NASDAQ:RGLS ) shareholders might be concerned after seeing the share price drop 10% in the...

CEO Compensation Analysis

How has Jay Hagan's remuneration changed compared to Regulus Therapeutics's earnings?
DateTotal CompensationSalaryCompany Earnings
Mar 31 2025n/an/a

-US$48m

Dec 31 2024US$4mUS$640k

-US$46m

Sep 30 2024n/an/a

-US$42m

Jun 30 2024n/an/a

-US$35m

Mar 31 2024n/an/a

-US$31m

Dec 31 2023US$3mUS$616k

-US$30m

Sep 30 2023n/an/a

-US$29m

Jun 30 2023n/an/a

-US$28m

Mar 31 2023n/an/a

-US$29m

Dec 31 2022US$1mUS$598k

-US$28m

Sep 30 2022n/an/a

-US$29m

Jun 30 2022n/an/a

-US$30m

Mar 31 2022n/an/a

-US$29m

Dec 31 2021US$2mUS$568k

-US$28m

Sep 30 2021n/an/a

-US$22m

Jun 30 2021n/an/a

-US$15m

Mar 31 2021n/an/a

-US$16m

Dec 31 2020US$2mUS$552k

-US$16m

Sep 30 2020n/an/a

-US$19m

Jun 30 2020n/an/a

-US$23m

Mar 31 2020n/an/a

-US$21m

Dec 31 2019US$2mUS$536k

-US$19m

Sep 30 2019n/an/a

-US$22m

Jun 30 2019n/an/a

-US$27m

Mar 31 2019n/an/a

-US$36m

Dec 31 2018US$2mUS$520k

-US$49m

Compensation vs Market: Jay's total compensation ($USD3.88M) is about average for companies of similar size in the US market ($USD3.97M).

Compensation vs Earnings: Jay's compensation has increased whilst the company is unprofitable.

CEO

Jay Hagan (56 yo)

8.1yrs
Tenure
US$3,881,443
Compensation

Mr. Joseph P. Hagan, also known as Jay, served as Independent Director of Zosano Pharma Corporation since May 22, 2015, until May 10, 2022. He has been the Chief Executive Officer and Director of Regulus T...

Leadership Team

NamePositionTenureCompensationOwnership
Joseph Hagan
CEO & Director8.1yrsUS$3.88m0.38%
$ 2.4m
Preston Klassen
President2yrsUS$2.24m0.064%
$ 392.2k
Crispina Calsada
Chief Financial Officer5.8yrsUS$1.93m0.075%
$ 462.9k
Daniel Penksa
VP of Finance & Controller5.9yrsno datano data
Christopher Aker
Senior VP14.3yrsUS$1.09m0.066%
$ 404.3k
Claire Padgett
Senior Vice President of Clinical Operations2.6yrsno datano data
Rekha Garg
Chief Medical Officer2.6yrsno datano data
Edmund Lee
Vice President of Translational Medicineno datano datano data
5.8yrs
Average Tenure
56yo
Average Age

Experienced Management: RGLS's management team is seasoned and experienced (5.8 years average tenure).

Board Members

NamePositionTenureCompensationOwnership
Joseph Hagan
CEO & Director8.1yrsUS$3.88m0.38%
$ 2.4m
Preston Klassen
President2yrsUS$2.24m0.064%
$ 392.2k
William Rastetter
Independent Director12.2yrsUS$184.52k0.052%
$ 318.7k
Timothy Wright
Member of the Scientific Advisory Board6.3yrsUS$1.48mno data
Stelios Papadopoulos
Independent Chairman of the Board16.4yrsUS$216.52k1.29%
$ 8.0m
David Baltimore
Chairman of the Scientific Advisory Board & Independent Director16.4yrsUS$180.52k0.029%
$ 180.9k
Jason Nunn
Independent Director6yrsUS$182.52k0%
$ 0
Thomas Tuschl
Member of the Scientific Advisory Boardno datano datano data
Markus Stoffel
Member of the Scientific Advisory Boardno datano datano data
Hugh Rosen
Independent Director9yrsUS$178.52k0.0023%
$ 14.4k
Kathryn Collier
Independent Director7.2yrsUS$192.52k0.014%
$ 86.1k
Pascale Witz
Independent Director8yrsUS$178.52k0.0063%
$ 38.6k
8.0yrs
Average Tenure
62yo
Average Age

Experienced Board: RGLS's board of directors are considered experienced (8 years average tenure).

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/06/25 00:23
End of Day Share Price 2025/06/24 00:00
Earnings2025/03/31
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Regulus Therapeutics Inc. is covered by 8 analysts. 6 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
James BirchenoughBMO Capital Markets Equity Research
Madhu KumarB. Riley Securities, Inc.
Madhu KumarChardan Capital Markets, LLC