Prothena Corporation plc

NasdaqGS:PRTA Stock Report

Market Cap: US$828.7m

Prothena Valuation

Is PRTA undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

4/6

Valuation Score 4/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Sales vs Peers

  • Price-To-Sales vs Industry

  • Price-To-Sales vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of PRTA when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: PRTA ($15.4) is trading below our estimate of fair value ($53.47)

Significantly Below Fair Value: PRTA is trading below fair value by more than 20%.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for PRTA?

Key metric: As PRTA is unprofitable we use its Price-To-Sales Ratio for relative valuation analysis.

The above table shows the Price to Sales ratio for PRTA. This is calculated by dividing PRTA's market cap by their current revenue.
What is PRTA's PS Ratio?
PS Ratio6.2x
SalesUS$133.35m
Market CapUS$828.65m

Price to Sales Ratio vs Peers

How does PRTA's PS Ratio compare to its peers?

The above table shows the PS ratio for PRTA vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PSEstimated GrowthMarket Cap
Peer Average7.3x
IMTX Immatics
7x-5.6%US$847.4m
GYRE Gyre Therapeutics
9.7xn/aUS$1.0b
CVAC CureVac
9.8x-11.5%US$670.7m
ICPT Intercept Pharmaceuticals
2.5x2.3%US$794.7m
PRTA Prothena
6.2x37.7%US$828.7m

Price-To-Sales vs Peers: PRTA is good value based on its Price-To-Sales Ratio (6.2x) compared to the peer average (8.9x).

Price to Sales Ratio vs Industry

How does PRTA's PS Ratio compare vs other companies in the US Biotechs Industry?

137 CompaniesPrice / SalesEstimated GrowthMarket Cap
BIIB Biogen
2.3x1.3%US$21.72b
MRNA Moderna
3x5.8%US$15.50b
INCY Incyte
3.3x8.9%US$13.47b
EXAS Exact Sciences
4x9.1%US$10.75b
PRTA 6.2xIndustry Avg. 9.9xNo. of Companies137PS01632486480+
137 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Sales vs Industry: PRTA is good value based on its Price-To-Sales Ratio (6.2x) compared to the US Biotechs industry average (9.9x).

Price to Sales Ratio vs Fair Ratio

What is PRTA's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

PRTA PS Ratio vs Fair Ratio.
Fair Ratio
Current PS Ratio6.2x
Fair PS Ratio4.2x

Price-To-Sales vs Fair Ratio: PRTA is expensive based on its Price-To-Sales Ratio (6.2x) compared to the estimated Fair Price-To-Sales Ratio (4.2x).

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst PRTA forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$15.40
US$49.75
+223.1%
49.2%US$94.00US$22.00n/a8
Dec ’25US$16.21
US$60.43
+272.8%
43.4%US$94.00US$24.00n/a7
Nov ’25US$16.65
US$61.14
+267.2%
41.4%US$94.00US$24.00n/a7
Oct ’25US$16.65
US$55.88
+235.6%
43.5%US$94.00US$24.00n/a8
Sep ’25US$22.27
US$62.50
+180.6%
37.7%US$94.00US$24.00n/a8
Aug ’25US$22.31
US$64.75
+190.2%
36.1%US$94.00US$28.00n/a8
Jul ’25US$20.48
US$64.75
+216.2%
36.1%US$94.00US$28.00n/a8
Jun ’25US$20.81
US$64.75
+211.1%
36.1%US$94.00US$28.00n/a8
May ’25US$21.42
US$66.09
+208.5%
32.3%US$94.00US$34.00n/a10
Apr ’25US$26.15
US$65.72
+151.3%
31.0%US$94.00US$34.00n/a11
Mar ’25US$28.53
US$66.08
+131.6%
30.0%US$94.00US$35.00n/a11
Feb ’25US$27.37
US$73.24
+167.6%
29.7%US$100.00US$36.00n/a12
Jan ’25US$36.34
US$81.66
+124.7%
30.9%US$129.00US$43.00n/a12
Dec ’24US$34.89
US$83.45
+139.2%
30.7%US$129.00US$43.00US$16.2111
Nov ’24US$36.68
US$87.89
+139.6%
26.2%US$129.00US$52.90US$16.6510
Oct ’24US$48.25
US$93.44
+93.7%
21.1%US$129.00US$60.00US$16.659
Sep ’24US$55.15
US$93.44
+69.4%
21.1%US$129.00US$60.00US$22.279
Aug ’24US$69.05
US$93.33
+35.2%
21.2%US$129.00US$60.00US$22.319
Jul ’24US$68.28
US$93.00
+36.2%
20.2%US$129.00US$60.00US$20.4810
Jun ’24US$66.39
US$92.10
+38.7%
18.7%US$120.00US$60.00US$20.8110
May ’24US$53.81
US$85.60
+59.1%
20.0%US$120.00US$55.00US$21.4210
Apr ’24US$48.47
US$84.10
+73.5%
21.6%US$120.00US$55.00US$26.1510
Mar ’24US$55.95
US$84.10
+50.3%
21.6%US$120.00US$55.00US$28.5310
Feb ’24US$53.67
US$84.60
+57.6%
21.0%US$120.00US$56.00US$27.3710
Jan ’24US$60.25
US$83.44
+38.5%
22.3%US$120.00US$55.00US$36.349
Dec ’23US$60.89
US$80.89
+32.8%
23.5%US$120.00US$55.00US$34.899

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2024/12/26 01:11
End of Day Share Price 2024/12/24 00:00
Earnings2024/09/30
Annual Earnings2023/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on .

Analyst Sources

Prothena Corporation plc is covered by 25 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Geoffrey MeachamBarclays
Tazeen AhmadBofA Global Research
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