Prime Medicine, Inc.

NasdaqGM:PRME Stock Report

Market Cap: US$352.2m

Prime Medicine Valuation

Is PRME undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

0/6

Valuation Score 0/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Book vs Peers

  • Price-To-Book vs Industry

  • Price-To-Book vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of PRME when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: Insufficient data to calculate PRME's fair value for valuation analysis.

Significantly Below Fair Value: Insufficient data to calculate PRME's fair value for valuation analysis.

Key Valuation Metric

Which metric is best to use when looking at relative valuation for PRME?

Key metric: As PRME barely has revenue we use its Price-To-Book Ratio for relative valuation analysis.

The above table shows the Price to Book ratio for PRME. This is calculated by dividing PRME's market cap by their current book value.
What is PRME's PB Ratio?
PB Ratio1.9x
BookUS$189.50m
Market CapUS$352.16m

Price to Book Ratio vs Peers

How does PRME's PB Ratio compare to its peers?

The above table shows the PB ratio for PRME vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PBEstimated GrowthMarket Cap
Peer Average1.7x
NGNE Neurogene
2.4x-29.9%US$335.4m
GLUE Monte Rosa Therapeutics
2.1x-7.1%US$433.1m
ZNTL Zentalis Pharmaceuticals
0.6x-1.2%US$229.5m
CMPX Compass Therapeutics
1.5x54.3%US$206.4m
PRME Prime Medicine
1.9x-2.5%US$352.2m

Price-To-Book vs Peers: PRME is expensive based on its Price-To-Book Ratio (1.9x) compared to the peer average (1.7x).

Price to Book Ratio vs Industry

How does PRME's PB Ratio compare vs other companies in the US Biotechs Industry?

68 CompaniesPrice / BookEstimated GrowthMarket Cap
GRAL GRAIL
0.2x35.7%US$632.03m
AMRN Amarin
0.4x-7.9%US$187.86m
LYEL Lyell Immunopharma
0.3x-14.9%US$171.13m
NKTX Nkarta
0.4x-11.5%US$165.84m
PRME 1.9xIndustry Avg. 1.7xNo. of Companies83PB01.63.24.86.48+
68 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Book vs Industry: PRME is expensive based on its Price-To-Book Ratio (1.9x) compared to the US Biotechs industry average (1.7x).

Price to Book Ratio vs Fair Ratio

What is PRME's PB Ratio compared to its Fair PB Ratio? This is the expected PB Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

PRME PB Ratio vs Fair Ratio.
Fair Ratio
Current PB Ratio1.9x
Fair PB Ration/a

Price-To-Book vs Fair Ratio: Insufficient data to calculate PRME's Price-To-Book Fair Ratio for valuation analysis.

Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst PRME forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$2.76
US$13.09
+374.3%
26.8%US$19.00US$7.00n/a11
Dec ’25US$3.29
US$12.64
+284.1%
32.8%US$19.00US$5.00n/a11
Nov ’25US$4.03
US$12.91
+220.3%
32.3%US$19.00US$5.00n/a11
Oct ’25US$3.45
US$13.45
+290.0%
25.4%US$19.00US$8.00n/a11
Sep ’25US$4.28
US$14.00
+227.1%
27.9%US$20.00US$8.00n/a11
Aug ’25US$5.19
US$14.18
+173.3%
26.7%US$20.00US$9.00n/a11
Jul ’25US$5.48
US$14.18
+158.8%
26.7%US$20.00US$9.00n/a11
Jun ’25US$6.48
US$14.18
+118.9%
26.7%US$20.00US$9.00n/a11
May ’25US$5.27
US$14.89
+182.5%
28.0%US$20.00US$9.00n/a9
Apr ’25US$6.76
US$15.43
+128.2%
33.0%US$23.00US$9.00n/a7
Mar ’25US$8.74
US$17.57
+101.0%
37.6%US$26.00US$9.00n/a7
Feb ’25US$6.71
US$18.86
+181.0%
29.8%US$26.00US$10.00n/a7
Jan ’25US$8.86
US$18.86
+112.8%
29.8%US$26.00US$10.00n/a7
Dec ’24US$8.06
US$21.33
+164.7%
14.7%US$26.00US$18.00US$3.296
Nov ’24US$6.42
US$22.00
+242.7%
15.7%US$27.00US$18.00US$4.036
Oct ’24US$9.54
US$22.60
+136.9%
15.5%US$27.00US$18.00US$3.455
Sep ’24US$12.78
US$22.33
+74.8%
14.5%US$27.00US$18.00US$4.286
Aug ’24US$14.84
US$22.67
+52.7%
13.2%US$27.00US$18.00US$5.196
Jul ’24US$14.65
US$22.40
+52.9%
14.3%US$27.00US$18.00US$5.485
Jun ’24US$14.76
US$22.40
+51.8%
14.3%US$27.00US$18.00US$6.485
May ’24US$14.01
US$22.60
+61.3%
13.9%US$27.00US$18.00US$5.275
Apr ’24US$12.30
US$23.75
+93.1%
10.0%US$27.00US$21.00US$6.764
Mar ’24US$16.34
US$23.75
+45.3%
10.0%US$27.00US$21.00US$8.744
Feb ’24US$17.65
US$23.75
+34.6%
10.0%US$27.00US$21.00US$6.714
Jan ’24US$18.58
US$24.25
+30.5%
7.9%US$27.00US$22.00US$8.864
Dec ’23US$16.50
US$24.25
+47.0%
7.9%US$27.00US$22.00US$8.064

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2024/12/26 10:08
End of Day Share Price 2024/12/24 00:00
Earnings2024/09/30
Annual Earnings2023/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on .

Analyst Sources

Prime Medicine, Inc. is covered by 17 analysts. 14 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Konstantinos BiliourisBMO Capital Markets Equity Research
Yevgeniya LivshitsChardan Capital Markets, LLC
Samantha Lynn SemenkowCitigroup Inc