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OnKure Therapeutics, Inc.NasdaqGM:OKUR Stock Report

Market Cap US$133.3m
Share Price
US$3.56
US$20.2
82.4% undervalued intrinsic discount
1Y58.2%
7D4.7%
Portfolio Value
View

OnKure Therapeutics, Inc.

NasdaqGM:OKUR Stock Report

Market Cap: US$133.3m

OnKure Therapeutics (OKUR) Stock Overview

A clinical-stage biopharmaceutical company, focuses on the discovery and development of precision medicines that target biologically validated drivers of cancers and other diseases. More details

OKUR fundamental analysis
Snowflake Score
Valuation2/6
Future Growth2/6
Past Performance0/6
Financial Health6/6
Dividends0/6

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OnKure Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for OnKure Therapeutics
Historical stock prices
Current Share PriceUS$3.56
52 Week HighUS$5.38
52 Week LowUS$1.91
Beta0
1 Month Change-28.66%
3 Month Change34.85%
1 Year Change58.22%
3 Year Changen/a
5 Year Changen/a
Change since IPO-80.91%

Recent News & Updates

Analysis Article Jul 23

Is OnKure Therapeutics (NASDAQ:OKUR) In A Good Position To Deliver On Growth Plans?

Just because a business does not make any money, does not mean that the stock will go down. For example, although...

Recent updates

Analysis Article Jul 23

Is OnKure Therapeutics (NASDAQ:OKUR) In A Good Position To Deliver On Growth Plans?

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Analysis Article Mar 29

We're Keeping An Eye On OnKure Therapeutics' (NASDAQ:OKUR) Cash Burn Rate

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Seeking Alpha Oct 24

OnKure: Looking To Alter PI3K Inhibitor Targeting In Breast Cancer And Beyond

Summary Initial OnKure Therapeutics, Inc. data from the phase 1 PIKture-01 study, using OKI-219 for the treatment of patients with PI3Ka-H1047R breast cancer and solid tumors, is expected in Q4 of 2024. OKI-219 has 80X fold improved selectivity PI3K-a targeting versus wild-type PI3K-a, potentially allowing for higher dosing and reducing unwanted off-target effects. The merger with Reneo Pharmaceuticals and $65 million private placement boosts OnKure's cash to $139 million, funding operations into Q4 2026. Significant market opportunity exists with 15% of breast cancer patients expressing the PI3Ka-H1047R mutation, and the company aims to outperform competitors with greater selectivity of OKI-219. Read the full article on Seeking Alpha

Shareholder Returns

OKURUS BiotechsUS Market
7D4.7%-3.0%-0.3%
1Y58.2%32.9%26.7%

Return vs Industry: OKUR exceeded the US Biotechs industry which returned 28.1% over the past year.

Return vs Market: OKUR exceeded the US Market which returned 23.3% over the past year.

Price Volatility

Is OKUR's price volatile compared to industry and market?
OKUR volatility
OKUR Average Weekly Movement12.0%
Biotechs Industry Average Movement10.9%
Market Average Movement7.2%
10% most volatile stocks in US Market16.2%
10% least volatile stocks in US Market3.2%

Stable Share Price: OKUR's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: OKUR's weekly volatility (12%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
201145Nick Saccomanoonkuretherapeutics.com

OnKure Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision medicines that target biologically validated drivers of cancers and other diseases. Its lead product candidate includes OKI-219, a selective inhibitor of phosphoinositide 3-kinase alpha (PI3Ka) harboring the H1047R mutation that is in Phase 1 clinical trial for the treatment of solid tumors, including breast cancer. The company was founded in 2011 and is headquartered in Boulder, Colorado.

OnKure Therapeutics, Inc. Fundamentals Summary

How do OnKure Therapeutics's earnings and revenue compare to its market cap?
OKUR fundamental statistics
Market capUS$133.31m
Earnings (TTM)-US$58.75m
Revenue (TTM)n/a
0.0x
P/S Ratio
-2.4x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
OKUR income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$58.75m
Earnings-US$58.75m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-1.45
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did OKUR perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/20 22:24
End of Day Share Price 2026/05/20 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

OnKure Therapeutics, Inc. is covered by 4 analysts. 4 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Robert BurnsH.C. Wainwright & Co.
Soumit RoyJonesTrading Institutional Services, LLC
Andrew BerensLeerink Partners LLC