Neurogene Inc.

NasdaqGM:NGNE Stock Report

Market Cap: US$451.9m

Neurogene Past Earnings Performance

Past criteria checks 0/6

Neurogene's earnings have been declining at an average annual rate of -25.7%, while the Biotechs industry saw earnings growing at 36.2% annually. Revenues have been growing at an average rate of 14.4% per year.

Key information

-25.68%

Earnings growth rate

73.21%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate14.36%
Return on equity-41.48%
Net Marginn/a
Last Earnings Update31 Mar 2026

Recent past performance updates

No updates

Recent updates

Analysis Article Apr 20

Companies Like Neurogene (NASDAQ:NGNE) Are In A Position To Invest In Growth

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Feb 27

Neurogene: Stock Soars On FDA Designation For Rett Gene Therapy - I'd Remain Cautious

Summary Neurogene received FDA Breakthrough Therapy Designation for NGN-401 in Rett Syndrome, driving a >25% share price surge. NGN-401 showed clinically meaningful, durable, multidomain improvements in interim Phase 1/2 data, and the pivotal Embolden trial is underway. Despite positive regulatory momentum and a strong cash runway into 2028, I maintain a Hold rating due to sector headwinds and binary risk. Upcoming 2026 catalysts include Embolden data readout and BLA submission, but failure or safety issues could leave NGNE with no clinical assets. Read the full article on Seeking Alpha
Analysis Article Dec 31

Here's Why We're Not Too Worried About Neurogene's (NASDAQ:NGNE) Cash Burn Situation

We can readily understand why investors are attracted to unprofitable companies. For example, although...
Analysis Article Aug 13

We Think Neurogene (NASDAQ:NGNE) Can Afford To Drive Business Growth

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Mar 07

Neurogene: Potential To Target Root Cause Of Rett Syndrome With NGN-401

Summary Additional Neurogene Inc. interim update data from the phase 1/2 study, using AAV9 capsid gene therapy NGN-401 for treatment of patients with Rett syndrome, expected 2nd half of 2025. NGNE plans to provide an update on a potential registrational phase 3 study, using NGN-401 for the treatment of patients with Rett Syndrome, in the 1st half of 2025. The global Rett Syndrome market size is estimated to reach $1.6 billion by the end of 2037. Neurogene had $139 million as of September 30th of 2024 & did an oversubscribed $200 million private placement agreement; Cash on hand enough to fund operations into the 2nd half of 2027. Read the full article on Seeking Alpha
Seeking Alpha Nov 10

Neurogene: Interesting CNS Disease Company, Data Coming Soon

Summary Neurogene, formed from multiple mergers, has a $903M market cap with two phase 1/2 assets, NGN-401 for Rett Syndrome and NGN-101 for CLN5 Batten Disease. NGN-401, an AAV9 gene therapy for Rett Syndrome, shows early safety and efficacy but faces competition from Acadia's FDA-approved trofinetide. Financially, Neurogene has a cash runway until 2026 but may need fundraising post-positive phase 1/2 data; current valuation seems high. The investment thesis hinges on upcoming clinical data to differentiate Neurogene from competitors; cautious optimism until more data is available. Read the full article on Seeking Alpha
Seeking Alpha Mar 26

Neurogene Stock: Gene Therapy Specialist May Break Chain Of Failed Mergers

Summary Neurogene Inc., a clinical-stage company focused on genetic medicines for rare neurological diseases, has seen a significant increase in its share price since joining the Nasdaq in December 2023. The company is progressing two drug candidates, NGN-401 for Rett Syndrome and NGN-101 for CLN5 Batten Disease, with key milestones planned for 2024. Neurogene's success will depend on the outcome of its clinical programs and the potential of its proprietary "transgene regulation technology" platform. Read the full article on Seeking Alpha

Revenue & Expenses Breakdown

How Neurogene makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGM:NGNE Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 260-99280
31 Dec 250-90280
30 Sep 250-85280
30 Jun 250-84270
31 Mar 251-81260
31 Dec 241-75230
30 Sep 241-3190
30 Jun 2412170
31 Mar 2409140
31 Dec 23014110
30 Sep 230-51110
30 Jun 230-499-26
31 Mar 230-529-13
31 Dec 220-5590

Quality Earnings: NGNE is currently unprofitable.

Growing Profit Margin: NGNE is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: NGNE is unprofitable, and losses have increased over the past 5 years at a rate of 25.7% per year.

Accelerating Growth: Unable to compare NGNE's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: NGNE is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (54.5%).


Return on Equity

High ROE: NGNE has a negative Return on Equity (-41.48%), as it is currently unprofitable.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/06/09 07:55
End of Day Share Price 2026/06/09 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Neurogene Inc. is covered by 10 analysts. 7 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Whitney IjemCanaccord Genuity
Gum-Ming LoweCraig-Hallum Capital Group LLC
Debjit ChattopadhyayGuggenheim Securities, LLC