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NuCana plcNasdaqCM:NCNA Stock Report

Market Cap US$7.0m
Share Price
US$3.68
My Fair Value
n/a
1Y-98.8%
7D-6.6%
Portfolio Value
View

NuCana plc

NasdaqCM:NCNA Stock Report

Market Cap: US$7.0m

NuCana (NCNA) Stock Overview

A clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer. More details

NCNA fundamental analysis
Snowflake Score
Valuation2/6
Future Growth0/6
Past Performance0/6
Financial Health4/6
Dividends0/6

NCNA Community Fair Values

Create Narrative

See what 7 others think this stock is worth. Follow their fair value or set your own to get alerts.

NuCana plc Competitors

Price History & Performance

Summary of share price highs, lows and changes for NuCana
Historical stock prices
Current Share PriceUS$3.68
52 Week HighUS$332.00
52 Week LowUS$2.78
Beta1.62
1 Month Change-30.96%
3 Month Change-21.87%
1 Year Change-98.82%
3 Year Change-99.93%
5 Year Change-99.98%
Change since IPO-100.00%

Recent News & Updates

Recent updates

Can NuCana (NASDAQ:NCNA) Afford To Invest In Growth?

Aug 21
Can NuCana (NASDAQ:NCNA) Afford To Invest In Growth?

Here's Why NuCana (NASDAQ:NCNA) Must Use Its Cash Wisely

Mar 14
Here's Why NuCana (NASDAQ:NCNA) Must Use Its Cash Wisely

We're Keeping An Eye On NuCana's (NASDAQ:NCNA) Cash Burn Rate

Oct 15
We're Keeping An Eye On NuCana's (NASDAQ:NCNA) Cash Burn Rate

Here's Why We're A Bit Worried About NuCana's (NASDAQ:NCNA) Cash Burn Situation

Jul 01
Here's Why We're A Bit Worried About NuCana's (NASDAQ:NCNA) Cash Burn Situation

Here's Why We're Watching NuCana's (NASDAQ:NCNA) Cash Burn Situation

Mar 15
Here's Why We're Watching NuCana's (NASDAQ:NCNA) Cash Burn Situation

Here's Why We're Watching NuCana's (NASDAQ:NCNA) Cash Burn Situation

Nov 30
Here's Why We're Watching NuCana's (NASDAQ:NCNA) Cash Burn Situation

NuCana: An Intriguing 'Sum Of The Parts' Story

Sep 22

NuCana GAAP EPS of -£0.07

Aug 17

NuCana regains Nasdaq compliance

Jul 27

NuCana: Improving Chemotherapy And A Major Patent Litigation Win Against Gilead

Jul 13

Here's Why We're Watching NuCana's (NASDAQ:NCNA) Cash Burn Situation

May 02
Here's Why We're Watching NuCana's (NASDAQ:NCNA) Cash Burn Situation

We Think NuCana (NASDAQ:NCNA) Can Easily Afford To Drive Business Growth

Jan 17
We Think NuCana (NASDAQ:NCNA) Can Easily Afford To Drive Business Growth

NuCana: Preparing For A Critical 2022

Dec 08

We're Interested To See How NuCana (NASDAQ:NCNA) Uses Its Cash Hoard To Grow

Sep 30
We're Interested To See How NuCana (NASDAQ:NCNA) Uses Its Cash Hoard To Grow

NuCana: The Market Continues To Overlook Its ProTide Platform Technology

Sep 11

We Think NuCana (NASDAQ:NCNA) Can Afford To Drive Business Growth

Jun 01
We Think NuCana (NASDAQ:NCNA) Can Afford To Drive Business Growth

Companies Like NuCana (NASDAQ:NCNA) Are In A Position To Invest In Growth

Feb 15
Companies Like NuCana (NASDAQ:NCNA) Are In A Position To Invest In Growth

How Many NuCana plc (NASDAQ:NCNA) Shares Do Institutions Own?

Dec 22
How Many NuCana plc (NASDAQ:NCNA) Shares Do Institutions Own?

Shareholder Returns

NCNAUS BiotechsUS Market
7D-6.6%-0.5%-2.0%
1Y-98.8%-1.1%12.1%

Return vs Industry: NCNA underperformed the US Biotechs industry which returned -1.1% over the past year.

Return vs Market: NCNA underperformed the US Market which returned 12.1% over the past year.

Price Volatility

Is NCNA's price volatile compared to industry and market?
NCNA volatility
NCNA Average Weekly Movement21.0%
Biotechs Industry Average Movement11.0%
Market Average Movement6.4%
10% most volatile stocks in US Market17.0%
10% least volatile stocks in US Market3.0%

Stable Share Price: NCNA's share price has been volatile over the past 3 months compared to the US market.

Volatility Over Time: NCNA's weekly volatility has decreased from 37% to 21% over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
199721Hugh Griffithwww.nucana.com

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company is developing medicines to overcome the limitations of nucleoside analogs and generate anti-cancer metabolites in cancer cells.

NuCana plc Fundamentals Summary

How do NuCana's earnings and revenue compare to its market cap?
NCNA fundamental statistics
Market capUS$7.02m
Earnings (TTM)-US$41.77m
Revenue (TTM)n/a
0.0x
P/S Ratio
-0.2x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
NCNA income statement (TTM)
RevenueUK£0
Cost of RevenueUK£0
Gross ProfitUK£0
Other ExpensesUK£31.75m
Earnings-UK£31.75m

Last Reported Earnings

Jun 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-16.64
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did NCNA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/11/10 08:56
End of Day Share Price 2025/11/07 00:00
Earnings2025/06/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

NuCana plc is covered by 4 analysts. 0 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Yigal NochomovitzCitigroup Inc
Eun Kyung YangJefferies LLC
Joseph CatanzaroPiper Sandler Companies