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Krystal Biotech, Inc.NasdaqGS:KRYS Stock Report

Market Cap US$8.1b
Share Price
US$258.81
n/a
1Y50.6%
7D-5.7%
Portfolio Value
View

Krystal Biotech, Inc.

NasdaqGS:KRYS Stock Report

Market Cap: US$8.1b

Krystal Biotech (KRYS) Stock Overview

A commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. More details

KRYS fundamental analysis
Snowflake Score
Valuation3/6
Future Growth5/6
Past Performance5/6
Financial Health6/6
Dividends0/6

KRYS Community Fair Values

Create Narrative

See what 58 others think this stock is worth. Follow their fair value or set your own to get alerts.

US$291.22
FV
11.1% undervalued intrinsic discount
33.38%
Revenue growth p.a.
245
users have viewed this narrative
0users have liked this narrative
0users have commented on this narrative
23users have followed this narrative
US$233.91
FV
10.6% overvalued intrinsic discount
3.86%
Revenue growth p.a.
25
users have viewed this narrative
0users have liked this narrative
0users have commented on this narrative
1users have followed this narrative
US$21.53
67.5% undervalued intrinsic discount
stuart_roberts's Fair Value
Profit Margin
20%
Future PE
27x
Price in 2030
US$34.67

Krystal Biotech, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Krystal Biotech
Historical stock prices
Current Share PriceUS$258.81
52 Week HighUS$298.30
52 Week LowUS$122.80
Beta0.48
1 Month Change-7.32%
3 Month Change20.34%
1 Year Change50.62%
3 Year Change236.51%
5 Year Change269.20%
Change since IPO2,332.42%

Recent News & Updates

The Rare Disease Rocket Ship

Krystal Biotech reports tomorrow, February 17, 2026. The narrative is no longer about survival; it’s about dominance.

Recent updates

The Rare Disease Rocket Ship

Krystal Biotech reports tomorrow, February 17, 2026. The narrative is no longer about survival; it’s about dominance.

Krystal Biotech: KB707 Program Bolstered By RMAT And 2nd Half 2026 Update

Feb 10

Investors Shouldn't Be Too Comfortable With Krystal Biotech's (NASDAQ:KRYS) Earnings

Nov 10
Investors Shouldn't Be Too Comfortable With Krystal Biotech's (NASDAQ:KRYS) Earnings

Market Participants Recognise Krystal Biotech, Inc.'s (NASDAQ:KRYS) Earnings Pushing Shares 29% Higher

Oct 09
Market Participants Recognise Krystal Biotech, Inc.'s (NASDAQ:KRYS) Earnings Pushing Shares 29% Higher

Why We're Not Concerned Yet About Krystal Biotech, Inc.'s (NASDAQ:KRYS) 26% Share Price Plunge

May 23
Why We're Not Concerned Yet About Krystal Biotech, Inc.'s (NASDAQ:KRYS) 26% Share Price Plunge

Should You Be Adding Krystal Biotech (NASDAQ:KRYS) To Your Watchlist Today?

Apr 21
Should You Be Adding Krystal Biotech (NASDAQ:KRYS) To Your Watchlist Today?

Krystal Biotech Soars As Q4 Earnings Put Blockbuster Commercialization In Focus

Feb 21

Krystal Biotech: Q4 Catalysts Expected With VYJUVEK Revenue Growth Pressing On

Oct 14
User avatar

Expanding Global Reach With VYJUVEK Set To Skyrocket Revenue And Sharpen Market Edge

International expansion and upcoming product launches indicate significant potential for revenue growth and market diversification.

Krystal Biotech: High Valuation Merits Caution Ahead Of Q2 Earnings (Rating Downgrade)

Jul 31

Krystal Biotech's Future Brightens With Vyjuvek's Robust Launch

Feb 28

Krystal Biotech: Ready For Launch

Feb 20

Shareholder Returns

KRYSUS BiotechsUS Market
7D-5.7%1.2%-0.6%
1Y50.6%28.8%15.5%

Return vs Industry: KRYS exceeded the US Biotechs industry which returned 28.8% over the past year.

Return vs Market: KRYS exceeded the US Market which returned 15.5% over the past year.

Price Volatility

Is KRYS's price volatile compared to industry and market?
KRYS volatility
KRYS Average Weekly Movement5.9%
Biotechs Industry Average Movement10.7%
Market Average Movement6.6%
10% most volatile stocks in US Market16.0%
10% least volatile stocks in US Market3.1%

Stable Share Price: KRYS has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: KRYS's weekly volatility (6%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
2016295Krish Krishnanwww.krystalbio.com

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb.

Krystal Biotech, Inc. Fundamentals Summary

How do Krystal Biotech's earnings and revenue compare to its market cap?
KRYS fundamental statistics
Market capUS$8.06b
Earnings (TTM)US$204.83m
Revenue (TTM)US$389.13m
36.9x
P/E Ratio
19.4x
P/S Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
KRYS income statement (TTM)
RevenueUS$389.13m
Cost of RevenueUS$23.05m
Gross ProfitUS$366.08m
Other ExpensesUS$161.25m
EarningsUS$204.83m

Last Reported Earnings

Dec 31, 2025

Next Earnings Date

n/a

Earnings per share (EPS)7.01
Gross Margin94.08%
Net Profit Margin52.64%
Debt/Equity Ratio0%

How did KRYS perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/03/02 05:36
End of Day Share Price 2026/03/02 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Krystal Biotech, Inc. is covered by 20 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Caroline PalomequeBerenberg
Alec StranahanBofA Global Research
Justin ZelinB. Riley Securities, Inc.