Crinetics Pharmaceuticals Future Growth
Future criteria checks 2/6
Crinetics Pharmaceuticals is forecast to grow earnings and revenue by 54.2% and 56% per annum respectively. EPS is expected to grow by 53.3% per annum. Return on equity is forecast to be -28% in 3 years.
Key information
54.2%
Earnings growth rate
53.26%
EPS growth rate
| Pharmaceuticals earnings growth | 19.0% |
| Revenue growth rate | 56.0% |
| Future return on equity | -27.97% |
| Analyst coverage | Good |
| Last updated | 21 Aug 2026 |
Recent future growth updates
Recent updates
Narrative Update • Jul 28
CRNX: Vertex Deal Price Will Anchor Shares As Endocrine Data Progresses
Crinetics Pharmaceuticals' analyst price target has reset toward the agreed $85 per share cash acquisition price, with updated models reflecting the $85.50 fair value estimate and the view from multiple firms that the Vertex deal now anchors both the upside and downside scenarios. Analyst Commentary Recent research on Crinetics Pharmaceuticals points to a clear shift in focus toward the US$85 per share cash offer from Vertex Pharmaceuticals as the key reference point for valuation.
Narrative Update • Jul 10
CRNX: Takeover Offer And Delayed Rival Entry Will Shape Endocrine Outlook
Crinetics Pharmaceuticals' analyst fair value estimate has been trimmed from $97 to $90 as analysts recalibrate expectations around the $85 per share cash acquisition by Vertex Pharmaceuticals and the cluster of rating downgrades to Hold or Neutral that now anchor views closer to the agreed deal price. Analyst Commentary Analysts covering Crinetics Pharmaceuticals are now largely treating the stock as a merger arbitrage situation, with ratings concentrated around Hold or Neutral and price targets aligning closely with the agreed US$85 per share cash offer from Vertex Pharmaceuticals.Seeking Alpha • Jul 07
Vertex To Acquire Crinetics For ~$10bn - What Investors Should Know
Summary Vertex Pharmaceuticals Incorporated acquires Crinetics Pharmaceuticals, Inc. for $85/share, valuing the deal at ~$10bn to diversify beyond its cystic fibrosis franchise. CRNX brings PALSONIFY, a newly approved oral acromegaly therapy with blockbuster potential, and atumelnant, a Phase 3 CAH candidate, strengthening VRTX's rare disease portfolio. VRTX expects Crinetics' assets to deliver up to $5bn peak annual revenues, supporting a path toward five blockbuster products and ~$20bn revenues by 2030. The CRNX acquisition is funded by cash and debt, leveraging VRTX's strong balance sheet, with anticipated deal closure in Q3 2026 and minimal near-term financial strain. Read the full article on Seeking AlphaNarrative Update • Jun 26
CRNX: Delayed Rival Entry Will Support Early Acromegaly Launch Execution
The analyst fair value estimate for Crinetics Pharmaceuticals has been revised from $108.00 to $97.00, with analysts citing a reset to more moderate revenue growth, a slightly higher discount rate, and updated assumptions around future margins and P/E multiples, even as they highlight potential benefits from delayed competitive pressure in acromegaly following the Oclaiz complete response letter. Analyst Commentary Recent research coverage on Crinetics Pharmaceuticals highlights a mix of valuation resets and constructive views on the launch setup for Palsonify in acromegaly.Analysis Article • Jun 19
Crinetics Pharmaceuticals (CRNX) Stock Could Be 56.5% Undervalued After ENDO 2026 Data
Crinetics Pharmaceuticals (CRNX) is back in focus after presenting extensive new data at the Endocrine Society’s 2026 meeting, covering both its approved acromegaly drug PALSONIFY and its investigational ACTH receptor antagonist atumelnant. See our latest analysis for Crinetics Pharmaceuticals. Crinetics Pharmaceuticals’ recent ENDO 2026 updates have arrived alongside a mixed share price picture, with a 7 day share price return of 6.98% contrasting with a year to date decline of 23.24%, while...Analysis Article • May 13
Industry Analysts Just Upgraded Their Crinetics Pharmaceuticals, Inc. (NASDAQ:CRNX) Revenue Forecasts By 11%
Crinetics Pharmaceuticals, Inc. ( NASDAQ:CRNX ) shareholders will have a reason to smile today, with the analysts...Seeking Alpha • Jan 02
Crinetics Pharmaceuticals: Attractive Speculative Bet On Market Weakness
Summary Crinetics Pharmaceuticals is currently overvalued but holds strong Wall Street support with a $75.07 average price target, indicating a 47.43% upside. The FDA accepted Crinetics' NDA for paltusotine, setting a PDUFA date of 09/24/2025. Crinetics is preparing for a fall 2025 launch of paltusotine, engaging with payers and endocrinologists to ensure broad patient access and formulary placement. Despite its valuation, Crinetics' advancements in acromegaly treatment and strong Wall Street backing make it a hold and potential acquisition on pullbacks. Read the full article on Seeking AlphaSeeking Alpha • Aug 12
Crinetics Pharmaceuticals: Stop, Look, And Listen Before Buying This High-Priced Clinical Stage Biotech
Summary Paltusotine in the treatment of acromegaly is Crinetics lead therapy with NDA filing planned in H2 2024. Crinetics has no approved drug and its lead therapy will face significant competition once approved. Investors should be aware of the high-risk nature of investing in Crinetics Pharmaceuticals. Read the full article on Seeking AlphaSeeking Alpha • May 23
Crinetics: Earlier Data Release For CAH Treatment Bodes Well For Upcoming Conference Data
Summary Positive data released from 4 patients from phase 2 study that took Atumelnant for congenital adrenal hyperplasia, showing reductions in key biomarkers of A4 and 17-OHP. An NDA submission of Paltusotine for the treatment of patients with Acromegaly expected in the 2nd half of 2024. Additional results from phase 2 open-label study, using Atumelnant for patients with CAH, to be presented at ENDO Conference on June 3rd 2024 at 12:00 to 1:30 p.m. ET. Pending positive talks with FDA, possible initiation of phase 3 study using Paltusotine for the treatment of patients with Carcinoid Syndrome by end of 2024. Read the full article on Seeking AlphaEarnings and Revenue Growth Forecasts
| Date | Revenue | Earnings | Free Cash Flow | Cash from Op | Avg. No. Analysts |
|---|---|---|---|---|---|
| 12/31/2028 | 436 | -286 | -220 | -339 | 7 |
| 12/31/2027 | 180 | -463 | -361 | -367 | 12 |
| 12/31/2026 | 77 | -507 | -418 | -391 | 12 |
| 6/30/2026 | 42 | -502 | -425 | -423 | N/A |
| 3/31/2026 | 18 | -496 | -420 | -414 | N/A |
| 12/31/2025 | 8 | -465 | -384 | -378 | N/A |
| 9/30/2025 | 2 | -423 | -354 | -348 | N/A |
| 6/30/2025 | 1 | -370 | -310 | -304 | N/A |
| 3/31/2025 | 1 | -328 | -270 | -266 | N/A |
| 12/31/2024 | 1 | -298 | -234 | -230 | N/A |
| 9/30/2024 | 1 | -278 | -206 | -202 | N/A |
| 6/30/2024 | 1 | -259 | -187 | -180 | N/A |
| 3/31/2024 | 2 | -235 | -184 | -178 | N/A |
| 12/31/2023 | 4 | -215 | -173 | -169 | N/A |
| 9/30/2023 | 5 | -199 | -167 | -163 | N/A |
| 6/30/2023 | 5 | -184 | -161 | -160 | N/A |
| 3/31/2023 | 4 | -175 | -144 | -142 | N/A |
| 12/31/2022 | 5 | -164 | -117 | -115 | N/A |
| 9/30/2022 | 5 | -150 | -104 | -103 | N/A |
| 6/30/2022 | 5 | -136 | -91 | -90 | N/A |
| 3/31/2022 | 4 | -119 | -82 | -82 | N/A |
| 12/31/2021 | 1 | -108 | -89 | -89 | N/A |
| 9/30/2021 | N/A | -98 | -82 | -82 | N/A |
| 6/30/2021 | N/A | -89 | -74 | -74 | N/A |
| 3/31/2021 | N/A | -79 | -70 | -70 | N/A |
| 12/31/2020 | 0 | -74 | -62 | -62 | N/A |
| 9/30/2020 | 0 | -67 | -60 | -60 | N/A |
| 6/30/2020 | 1 | -63 | -55 | -55 | N/A |
| 3/31/2020 | 1 | -59 | N/A | -52 | N/A |
| 12/31/2019 | 1 | -50 | N/A | -46 | N/A |
| 9/30/2019 | 2 | -44 | N/A | -39 | N/A |
| 6/30/2019 | 2 | -38 | N/A | -31 | N/A |
| 3/31/2019 | 2 | -31 | N/A | -23 | N/A |
| 12/31/2018 | 2 | -27 | N/A | -19 | N/A |
| 9/30/2018 | 2 | -21 | N/A | -16 | N/A |
| 6/30/2018 | 2 | -16 | N/A | -13 | N/A |
| 3/31/2018 | 2 | -12 | N/A | -11 | N/A |
| 12/31/2017 | 2 | -9 | N/A | -9 | N/A |
| 12/31/2016 | 1 | -6 | N/A | -5 | N/A |
Analyst Future Growth Forecasts
Earnings vs Savings Rate: CRNX is forecast to remain unprofitable over the next 3 years.
Earnings vs Market: CRNX is forecast to remain unprofitable over the next 3 years.
High Growth Earnings: CRNX is forecast to remain unprofitable over the next 3 years.
Revenue vs Market: CRNX's revenue (56% per year) is forecast to grow faster than the US market (12.9% per year).
High Growth Revenue: CRNX's revenue (56% per year) is forecast to grow faster than 20% per year.
Earnings per Share Growth Forecasts
Future Return on Equity
Future ROE: CRNX is forecast to be unprofitable in 3 years.
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Company Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2026/08/24 23:11 |
| End of Day Share Price | 2026/08/24 00:00 |
| Earnings | 2026/06/30 |
| Annual Earnings | 2025/12/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
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| Analyst Consensus Estimates | +3 years |
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| Market Prices | 30 years |
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| Ownership | 10 years |
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| Management | 10 years |
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| Key Developments | 10 years |
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* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
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Industry and Sector Metrics
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Analyst Sources
Crinetics Pharmaceuticals, Inc. is covered by 21 analysts. 12 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| Brian Skorney | Baird |
| Joshua Schimmer | Cantor Fitzgerald & Co. |
| David Lebowitz | Citigroup Inc |