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Centessa Pharmaceuticals plcNasdaqGS:CNTA Stock Report

Market Cap US$2.2b
Share Price
US$16.65
My Fair Value
US$32
47.8% undervalued intrinsic discount
1Y27.7%
7D-5.0%
Portfolio Value
View

Centessa Pharmaceuticals plc

NasdaqGS:CNTA Stock Report

Market Cap: US$2.2b

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Centessa Pharmaceuticals plc Competitors

Price History & Performance

Summary of share price highs, lows and changes for Centessa Pharmaceuticals
Historical stock prices
Current Share PriceUS$16.65
52 Week HighUS$19.09
52 Week LowUS$9.60
Beta1.49
1 Month Change9.47%
3 Month Change23.24%
1 Year Change27.68%
3 Year Change266.74%
5 Year Changen/a
Change since IPO-23.45%

Recent News & Updates

Centessa Pharmaceuticals (NASDAQ:CNTA) Is Using Debt Safely

Jul 17
Centessa Pharmaceuticals (NASDAQ:CNTA) Is Using Debt Safely

Recent updates

Centessa Pharmaceuticals (NASDAQ:CNTA) Is Using Debt Safely

Jul 17
Centessa Pharmaceuticals (NASDAQ:CNTA) Is Using Debt Safely

Is There An Opportunity With Centessa Pharmaceuticals plc's (NASDAQ:CNTA) 50% Undervaluation?

Apr 19
Is There An Opportunity With Centessa Pharmaceuticals plc's (NASDAQ:CNTA) 50% Undervaluation?

Does Centessa Pharmaceuticals (NASDAQ:CNTA) Have A Healthy Balance Sheet?

Mar 15
Does Centessa Pharmaceuticals (NASDAQ:CNTA) Have A Healthy Balance Sheet?

Are Investors Undervaluing Centessa Pharmaceuticals plc (NASDAQ:CNTA) By 30%?

Jan 02
Are Investors Undervaluing Centessa Pharmaceuticals plc (NASDAQ:CNTA) By 30%?

Centessa Pharmaceuticals: Orexin Franchise Worth Monitoring

Dec 31

Is Centessa Pharmaceuticals (NASDAQ:CNTA) Using Debt Sensibly?

Nov 14
Is Centessa Pharmaceuticals (NASDAQ:CNTA) Using Debt Sensibly?

Centessa Pharmaceuticals: Progressing SerpinPC Through Registrational Trials In Hemophilia B

Sep 25

Centessa Pharmaceuticals (NASDAQ:CNTA) Has Debt But No Earnings; Should You Worry?

Aug 15
Centessa Pharmaceuticals (NASDAQ:CNTA) Has Debt But No Earnings; Should You Worry?

Centessa: Hemophilia B Data Readout In 2024 Is Major Turning Point

Apr 24

Health Check: How Prudently Does Centessa Pharmaceuticals (NASDAQ:CNTA) Use Debt?

Mar 07
Health Check: How Prudently Does Centessa Pharmaceuticals (NASDAQ:CNTA) Use Debt?

Centessa Pharmaceuticals snaps multi-day losing streak; up 10%

Oct 20

Centessa hemophilia B therapy SerpinPC gets FDA orphan drug status

Sep 14

Centessa Pharmaceuticals GAAP EPS of -$0.69

Aug 10

Checking In On Centessa Pharmaceuticals

Dec 23

Shareholder Returns

CNTAUS BiotechsUS Market
7D-5.0%-1.1%1.9%
1Y27.7%-8.9%17.5%

Return vs Industry: CNTA exceeded the US Biotechs industry which returned -8.9% over the past year.

Return vs Market: CNTA exceeded the US Market which returned 17.5% over the past year.

Price Volatility

Is CNTA's price volatile compared to industry and market?
CNTA volatility
CNTA Average Weekly Movement7.0%
Biotechs Industry Average Movement10.7%
Market Average Movement6.5%
10% most volatile stocks in US Market17.3%
10% least volatile stocks in US Market3.0%

Stable Share Price: CNTA has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: CNTA's weekly volatility (7%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
202098Saurabh Sahacentessa.com

Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines. Its lead clinical-stage program includes ORX750, an orally administered OX2R agonist in a Phase 2a study for the treatment of idiopathic hypersomnia and narcolepsy type 1 and 2. The company also develops ORX142 for the treatment of neurological and neurodegenerative disorders, as well as other potential symptoms, including excessive daytime sleepiness, impaired attention, cognitive deficits, and fatigue; and ORX489 for the treatment of neuropsychiatric disorders.

Centessa Pharmaceuticals plc Fundamentals Summary

How do Centessa Pharmaceuticals's earnings and revenue compare to its market cap?
CNTA fundamental statistics
Market capUS$2.23b
Earnings (TTM)-US$230.37m
Revenue (TTM)US$15.00m
148.8x
P/S Ratio
-9.7x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
CNTA income statement (TTM)
RevenueUS$15.00m
Cost of RevenueUS$0
Gross ProfitUS$15.00m
Other ExpensesUS$245.37m
Earnings-US$230.37m

Last Reported Earnings

Jun 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-1.72
Gross Margin100.00%
Net Profit Margin-1,535.82%
Debt/Equity Ratio31.8%

How did CNTA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/08/28 18:38
End of Day Share Price 2025/08/27 00:00
Earnings2025/06/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Centessa Pharmaceuticals plc is covered by 19 analysts. 11 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
null nullBMO Capital Markets Equity Research
Konstantinos BiliourisBMO Capital Markets Equity Research
Mayank MamtaniB. Riley Securities, Inc.