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Updated 1m ago
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Crescent Biopharma, Inc.NasdaqCM:CBIO Stock Report

Market Cap US$722.9m
Updated 1m ago
Share Price
n/a
1Y30.7%
7D-13.0%
1D0.7%
Portfolio Value
​
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Crescent Biopharma, Inc.

NasdaqCM:CBIO Stock Report

Market Cap: US$722.9m

  • Company Overview
    • Valuation
    • Future Growth
    • Past Performance
    • Financial Health
    • Dividend
  • Management
  • Ownership
  • Other Information
  • Stock Community

Crescent Biopharma (CBIO) Stock Overview

A biotechnology company, researches and develops cancer therapy candidates in the United States. More details

CBIO fundamental analysis
Snowflake Score
Valuation2/6
Future Growth2/6
Past Performance0/6
Financial Health6/6
Dividends0/6

Rewards

Revenue is forecast to grow 56.2% per year

Revenue grew by 121% over the past year

Analysts in good agreement that stock price will rise by 81.2%

Risk Analysis

Shareholders have been substantially diluted in the past year

Earnings are forecast to decline by an average of 13.1% per year for the next 3 years

Currently unprofitable and not forecast to become profitable over the next 3 years


CBIO Community Fair Values

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US$
Current Price
US$16.89719.9% overvalued intrinsic discount
%/yr
Decrease
Increase
PastFuture-247m110m2016201920222025202620282031Revenue US$110.5mEarnings US$19.1m
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Crescent Biopharma, Inc. Competitors

Nuvectis Pharma

Symbol: NasdaqCM:NVCT
Market cap: US$716.8m

Silence Therapeutics

Symbol: NasdaqGM:SLN
Market cap: US$734.6m

MiMedx Group

Symbol: NasdaqCM:MDXG
Market cap: US$693.8m

Sagimet Biosciences

Symbol: NasdaqGM:SGMT
Market cap: US$688.7m

Price History & Performance

Summary of share price highs, lows and changes for Crescent Biopharma
Historical stock prices
Current Share PriceUS$16.89
52 Week HighUS$27.41
52 Week LowUS$8.72
Beta0
1 Month Change-1.52%
3 Month Change-3.87%
1 Year Change30.73%
3 Year Changen/a
5 Year Changen/a
Change since IPO6.93%

Recent News & Updates

Seeking Alpha • Jun 29

Crescent Biopharma: Intriguing Developer Of ADC/PD1-VEGF Assets May Not Be Sufficiently Derisked

Summary Crescent Biopharma is developing CR-001, a PD-1 x VEGF bispecific antibody, aiming to rival Keytruda as an immuno-oncology backbone. I see Crescent's dual strategy—advancing CR-001 and building a best-in-class ADC portfolio—as a bold but high-risk approach in a competitive landscape. Despite promising mechanisms, near-term catalysts are limited, and clinical proof for CR-001, CR-002, and CR-003 remains lacking. I rate CBIO a Hold, preferring to wait for derisking clinical data before considering a more aggressive position. Read the full article on Seeking Alpha
Analysis Article • May 07

Rainbows and Unicorns: Crescent Biopharma, Inc. (NASDAQ:CBIO) Analysts Just Became A Lot More Optimistic

Shareholders in Crescent Biopharma, Inc. ( NASDAQ:CBIO ) may be thrilled to learn that the analysts have just delivered...

Recent updates

Seeking Alpha • Jun 29

Crescent Biopharma: Intriguing Developer Of ADC/PD1-VEGF Assets May Not Be Sufficiently Derisked

Summary Crescent Biopharma is developing CR-001, a PD-1 x VEGF bispecific antibody, aiming to rival Keytruda as an immuno-oncology backbone. I see Crescent's dual strategy—advancing CR-001 and building a best-in-class ADC portfolio—as a bold but high-risk approach in a competitive landscape. Despite promising mechanisms, near-term catalysts are limited, and clinical proof for CR-001, CR-002, and CR-003 remains lacking. I rate CBIO a Hold, preferring to wait for derisking clinical data before considering a more aggressive position. Read the full article on Seeking Alpha
Analysis Article • May 07

Rainbows and Unicorns: Crescent Biopharma, Inc. (NASDAQ:CBIO) Analysts Just Became A Lot More Optimistic

Shareholders in Crescent Biopharma, Inc. ( NASDAQ:CBIO ) may be thrilled to learn that the analysts have just delivered...

Shareholder Returns

CBIOUS BiotechsUS Market
7D-13.0%0.6%-0.2%
1Y30.7%36.5%12.1%

Return vs Industry: CBIO underperformed the US Biotechs industry which returned 36.5% over the past year.

Return vs Market: CBIO exceeded the US Market which returned 12.1% over the past year.

Price Volatility

Is CBIO's price volatile compared to industry and market?
CBIO volatility
CBIO Average Weekly Movement10.2%
Biotechs Industry Average Movement9.5%
Market Average Movement6.8%
10% most volatile stocks in US Market15.1%
10% least volatile stocks in US Market2.9%

Stable Share Price: CBIO has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: CBIO's weekly volatility (10%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
202469Josh Brummcrescentbiopharma.com

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.

Crescent Biopharma, Inc. Fundamentals Summary

How do Crescent Biopharma's earnings and revenue compare to its market cap?
CBIO fundamental statistics
Market capUS$722.91m
Earnings (TTM)-US$165.12m
Revenue (TTM)US$11.88m
60.8x
P/S Ratio
-4.4x
P/E Ratio

Is CBIO overvalued?

See Fair Value and valuation analysis

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
CBIO income statement (TTM)
RevenueUS$11.88m
Cost of RevenueUS$0
Gross ProfitUS$11.88m
Other ExpensesUS$177.01m
Earnings-US$165.12m

Last Reported Earnings

Jun 30, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-3.86
Gross Margin100.00%
Net Profit Margin-1,389.58%
Debt/Equity Ratio0%

How did CBIO perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/09/20 06:14
End of Day Share Price 2026/09/18 00:00
Earnings2026/06/30
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
  • SEC Form 10-K
  • SEC Form 10-Q
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
  • Analyst Research Reports
  • Blue Matrix
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
  • ICE Market Data
  • SEC Form S-1
Ownership10 years
  • Top shareholders
  • Insider trading
  • SEC Form 4
  • SEC Form 13D
Management10 years
  • Leadership team
  • Board of directors
  • SEC Form 10-K
  • SEC Form DEF 14A
Key Developments10 years
  • Company announcements
  • SEC Form 8-K

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Crescent Biopharma, Inc. is covered by 9 analysts. 7 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Eric SchmidtCantor Fitzgerald & Co.
Bradley CaninoGuggenheim Securities, LLC
Mitchell KapoorH.C. Wainwright & Co.

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